Basic Information
ID: ALA1686369
Type: Binding
Description: Inhibition of ADAMTS-4 assessed as substrate cleavage by measuring increase in fluorescence after 16 hrs
Format: BAO_0000357
Target: ADAMTS4(ALA2318)
Document: ALA1681676
Inhibition of ADAMTS-4 assessed as substrate cleavage by measuring increase in fluorescence after 16 hrs: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1686369
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 563.48 | 4.03 | 4.03 |
| 511.62 | 3.00 | 3.00 |
| 469.51 | 1.62 | 1.62 |
| 549.45 | 3.64 | 3.64 |
| 483.54 | 2.01 | 2.01 |
| 562.50 | 3.21 | 3.21 |
| 561.51 | 4.70 | 4.70 |
| 562.50 | 3.61 | 3.61 |
| 595.06 | 5.06 | 5.06 |
| 541.09 | 4.35 | 4.35 |
| 589.50 | 4.29 | 4.29 |
| 545.05 | 4.18 | 4.18 |
| 578.60 | 4.55 | 4.55 |
| 524.63 | 3.84 | 3.84 |
| 574.64 | 4.72 | 4.72 |
| 600.68 | 5.29 | 5.29 |
| 520.67 | 4.01 | 4.01 |
| 521.66 | 3.40 | 3.40 |
| 521.66 | 3.40 | 3.40 |
| 527.69 | 3.46 | 3.46 |
| 521.66 | 3.40 | 3.40 |
| 596.05 | 4.46 | 4.46 |
| 575.63 | 4.11 | 4.11 |
| 605.15 | 3.45 | 3.45 |
| 510.64 | 2.43 | 2.43 |