Basic Information
ID: ALA1686709
Type: Binding
Description: Inhibition of mPGES-1 expressed in LPS-stimulated human A549 cells mitochondrial fraction assessed as conversion of PGH2 to PGE2
Format: BAO_0000219
Cell type: A549
Target: Prostaglandin E synthase(ALA5658)
Document: ALA1681685
Inhibition of mPGES-1 expressed in LPS-stimulated human A549 cells mitochondrial fraction assessed as conversion of PGH2 to PGE2: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1686709
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 472.09 | 8.01 | 8.01 |
| 449.96 | 6.56 | 6.56 |
| 471.97 | 7.10 | 7.10 |
| 456.35 | 6.60 | 6.60 |
| 463.99 | 6.25 | 6.25 |
| 449.96 | 6.56 | 6.56 |
| 534.13 | 8.54 | 8.54 |
| 498.01 | 7.61 | 7.61 |
| 498.01 | 7.61 | 7.61 |
| 523.02 | 7.48 | 7.48 |
| 504.06 | 7.99 | 7.99 |
| 514.01 | 7.74 | 7.74 |
| 512.03 | 7.48 | 7.48 |
| 512.03 | 7.54 | 7.54 |
| 510.02 | 7.52 | 7.52 |