ID: ALA1693386
Type: Binding
Description: Inhibition of Plasmodium falciparum falcipain 3 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence spectrophotometry
Organism: Plasmodium falciparum
Bioactivity
Activity Types for Assay ALA1693386
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
319.88 | 4.81 | 4.81 |
357.41 | -1.46 | -1.46 |
246.27 | 1.13 | 1.13 |
188.23 | 1.54 | 1.54 |
222.68 | 2.19 | 2.19 |
222.68 | 2.19 | 2.19 |
222.68 | 2.19 | 2.19 |
202.26 | 1.57 | 1.57 |
267.35 | 3.91 | 3.91 |
236.27 | 3.09 | 3.09 |
336.39 | 2.74 | 2.74 |
343.47 | 3.15 | 3.15 |
377.92 | 3.80 | 3.80 |
377.92 | 3.80 | 3.80 |
377.92 | 3.80 | 3.80 |
357.50 | 3.17 | 3.17 |
287.36 | 1.73 | 1.73 |
391.52 | 3.73 | 3.73 |
411.93 | 4.00 | 4.00 |
425.96 | 4.39 | 4.39 |
378.86 | 4.27 | 4.27 |
413.31 | 4.93 | 4.93 |
413.31 | 4.93 | 4.93 |
413.31 | 4.93 | 4.93 |
392.89 | 4.30 | 4.30 |
399.28 | 4.54 | 4.54 |