ID: ALA1697798
Type: ADME
Description: FDA HLAED, alkaline phosphatase increase
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA1697798
Alkaline Phosphatase Increase - Activity Score
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
383.41 | 1.78 | 1.78 |
162.24 | 1.85 | 1.85 |
361.37 | 1.54 | 1.54 |
357.79 | 3.93 | 3.93 |
331.35 | 1.58 | 1.58 |
319.34 | 1.27 | 1.27 |
365.84 | 2.08 | 2.08 |
303.29 | 1.77 | 1.77 |
430.38 | 2.88 | 2.88 |
284.75 | 3.15 | 3.15 |
267.37 | 1.61 | 1.61 |
252.27 | 1.77 | 1.77 |
314.86 | 4.53 | 4.53 |
231.09 | 1.81 | 1.81 |
454.61 | 5.09 | 5.09 |
398.40 | 3.70 | 3.70 |
414.53 | 3.37 | 3.37 |
266.34 | 0.45 | 0.45 |
180.16 | 1.31 | 1.31 |
407.51 | 4.95 | 4.95 |
307.43 | 2.39 | 2.39 |
302.24 | 2.91 | 2.91 |
328.41 | 2.14 | 2.14 |
297.75 | -0.35 | -0.35 |
330.75 | 1.89 | 1.89 |
250.28 | 0.86 | 0.86 |
300.44 | 5.60 | 5.60 |
262.31 | 1.31 | 1.31 |
309.33 | 4.44 | 4.44 |
326.83 | 3.72 | 3.72 |
263.38 | 3.83 | 3.83 |
250.34 | 3.57 | 3.57 |
293.37 | 3.13 | 3.13 |
385.51 | 2.09 | 2.09 |
211.22 | 0.44 | 0.44 |
302.37 | 3.57 | 3.57 |
375.87 | 4.43 | 4.43 |
340.43 | 2.88 | 2.88 |
354.49 | 5.65 | 5.65 |
266.30 | 2.65 | 2.65 |
314.47 | 5.74 | 5.74 |
444.49 | -0.14 | -0.14 |
76.05 | -0.96 | -0.96 |
414.41 | 2.41 | 2.41 |
137.14 | -0.31 | -0.31 |
255.27 | 2.29 | 2.29 |
272.37 | 1.09 | 1.09 |
494.01 | 3.64 | 3.64 |
267.25 | -1.98 | -1.98 |
370.59 | 5.89 | 5.89 |
369.37 | 3.52 | 3.52 |
586.69 | 4.09 | 4.09 |
232.28 | 1.35 | 1.35 |
329.37 | 3.33 | 3.33 |
371.52 | 6.00 | 6.00 |
654.61 | 3.19 | 3.19 |
421.45 | 1.85 | 1.85 |
410.49 | 3.59 | 3.59 |
299.80 | 2.00 | 2.00 |
853.92 | 3.74 | 3.74 |
354.49 | 3.48 | 3.48 |
261.09 | 1.88 | 1.88 |
316.43 | 0.50 | 0.50 |
248.33 | 1.91 | 1.91 |
924.09 | 0.71 | 0.71 |
236.30 | 2.73 | 2.73 |
198.27 | 2.70 | 2.70 |
404.55 | 4.20 | 4.20 |
296.15 | 4.74 | 4.74 |
214.05 | 1.16 | 1.16 |
187.20 | 1.02 | 1.02 |
339.48 | 3.36 | 3.36 |
206.28 | 3.07 | 3.07 |
178.27 | 3.64 | 3.64 |
331.35 | 1.58 | 1.58 |
383.41 | -0.56 | -0.56 |
749.00 | 1.90 | 1.90 |
314.50 | 4.27 | 4.27 |
733.94 | 1.79 | 1.79 |
384.59 | 4.16 | 4.16 |
306.28 | 0.74 | 0.74 |
300.44 | 5.60 | 5.60 |
208.26 | 1.16 | 1.16 |
236.27 | 3.39 | 3.39 |
144.21 | 2.29 | 2.29 |
179.26 | 2.03 | 2.03 |
351.35 | 1.80 | 1.80 |
352.77 | 2.81 | 2.81 |
244.26 | 3.68 | 3.68 |
151.16 | 1.35 | 1.35 |
403.98 | 3.94 | 3.94 |
356.42 | 4.37 | 4.37 |
254.29 | 3.11 | 3.11 |
238.16 | 0.07 | 0.07 |
376.45 | 1.60 | 1.60 |
670.86 | 3.09 | 3.09 |
613.80 | 2.87 | 2.87 |
369.43 | 2.74 | 2.74 |
471.69 | 6.45 | 6.45 |
336.48 | 4.14 | 4.14 |
163.20 | -0.49 | -0.49 |
341.41 | 1.53 | 1.53 |
575.69 | 5.70 | 5.70 |
382.54 | 3.95 | 3.95 |
146.24 | -1.92 | -1.92 |
291.73 | 2.85 | 2.85 |
387.44 | 1.06 | 1.06 |
383.47 | -0.31 | -0.31 |
371.87 | 2.36 | 2.36 |
287.36 | 3.38 | 3.38 |
470.02 | 3.55 | 3.55 |
287.41 | 4.99 | 4.99 |
278.31 | 0.19 | 0.19 |
277.41 | 4.17 | 4.17 |
295.41 | 1.32 | 1.32 |
341.45 | 3.24 | 3.24 |
392.47 | 1.90 | 1.90 |
645.32 | 6.94 | 6.94 |
416.53 | 1.38 | 1.38 |
358.43 | 1.77 | 1.77 |
277.41 | 3.04 | 3.04 |
267.24 | -0.20 | -0.20 |
381.91 | 4.30 | 4.30 |
235.33 | 1.34 | 1.34 |
336.43 | 2.37 | 2.37 |
294.44 | 4.12 | 4.12 |
325.45 | 2.37 | 2.37 |
343.22 | 4.23 | 4.23 |
245.11 | 1.76 | 1.76 |
374.48 | 1.80 | 1.80 |
414.35 | 3.44 | 3.44 |
230.10 | 2.36 | 2.36 |
265.36 | 2.48 | 2.48 |
325.77 | 4.32 | 4.32 |
272.39 | 3.61 | 3.61 |
386.56 | 4.21 | 4.21 |
151.25 | 1.91 | 1.91 |
308.77 | 3.58 | 3.58 |
277.41 | 4.21 | 4.21 |
126.00 | -0.16 | -0.16 |
171.16 | 0.09 | 0.09 |
275.40 | 4.55 | 4.55 |
189.22 | 0.16 | 0.16 |
367.81 | 0.62 | 0.62 |
244.29 | 2.67 | 2.67 |
295.30 | 2.97 | 2.97 |
296.15 | 4.36 | 4.36 |
241.29 | 3.75 | 3.75 |
143.14 | 0.37 | 0.37 |
213.66 | 1.86 | 1.86 |
517.56 | -0.24 | -0.24 |
153.14 | 0.67 | 0.67 |
451.48 | 1.72 | 1.72 |
372.55 | 3.81 | 3.81 |
229.26 | -0.59 | -0.59 |
239.31 | 1.31 | 1.31 |
312.44 | 3.44 | 3.44 |
386.53 | 4.66 | 4.66 |
500.63 | 2.59 | 2.59 |
406.48 | 3.74 | 3.74 |
437.53 | 4.31 | 4.31 |
167.20 | 0.60 | 0.60 |
75.07 | -0.49 | -0.49 |
256.10 | 2.01 | 2.01 |
234.20 | 2.78 | 2.78 |
371.35 | 2.48 | 2.48 |
376.50 | 5.12 | 5.12 |
295.38 | 1.53 | 1.53 |
327.47 | 3.37 | 3.37 |
294.75 | 3.27 | 3.27 |
454.45 | 0.27 | 0.27 |
209.25 | -0.13 | -0.13 |
230.26 | 3.04 | 3.04 |
378.32 | 4.45 | 4.45 |
243.22 | -2.56 | -2.56 |
276.21 | 3.21 | 3.21 |
381.69 | 5.80 | 5.80 |
306.24 | 5.18 | 5.18 |
312.42 | 2.32 | 2.32 |
318.34 | 3.20 | 3.20 |
246.31 | -0.28 | -0.28 |
291.44 | 4.88 | 4.88 |
320.32 | 0.66 | 0.66 |
327.81 | 3.77 | 3.77 |
263.79 | 3.96 | 3.96 |
235.07 | -1.66 | -1.66 |
435.44 | -1.17 | -1.17 |
546.59 | -1.30 | -1.30 |
424.50 | 2.57 | 2.57 |
292.38 | 1.70 | 1.70 |
292.14 | 1.76 | 1.76 |
416.65 | 5.70 | 5.70 |
392.41 | 2.08 | 2.08 |
305.21 | 1.93 | 1.93 |
211.22 | -0.50 | -0.50 |
458.58 | 5.35 | 5.35 |
218.26 | 0.54 | 0.54 |
246.10 | 1.55 | 1.55 |
204.31 | -0.29 | -0.29 |
320.34 | 2.73 | 2.73 |
588.56 | 1.34 | 1.34 |
249.10 | -1.27 | -1.27 |
206.03 | -0.99 | -0.99 |
321.34 | 0.54 | 0.54 |
263.20 | -1.29 | -1.29 |
239.75 | 3.30 | 3.30 |
357.45 | 1.71 | 1.71 |
374.91 | 3.06 | 3.06 |
285.37 | 2.20 | 2.20 |
250.20 | 3.04 | 3.04 |
337.46 | -0.77 | -0.77 |
543.53 | 0.00 | 0.00 |
307.40 | 3.25 | 3.25 |
501.67 | 5.51 | 5.51 |
246.19 | -1.68 | -1.68 |
554.59 | -1.20 | -1.20 |
301.39 | 2.96 | 2.96 |
197.38 | 2.51 | 2.51 |
720.96 | 5.91 | 5.91 |
171.24 | 1.37 | 1.37 |
405.97 | 6.56 | 6.56 |
260.31 | 3.17 | 3.17 |
179.31 | 2.55 | 2.55 |
296.55 | 3.62 | 3.62 |
300.75 | 2.47 | 2.47 |
324.81 | 3.93 | 3.93 |
352.74 | 4.09 | 4.09 |
187.29 | 2.18 | 2.18 |
164.18 | -0.20 | -0.20 |
705.65 | 5.58 | 5.58 |
312.41 | 2.53 | 2.53 |
339.44 | 2.51 | 2.51 |
1100.18 | ||
317.48 | 5.77 | 5.77 |
224.22 | -0.71 | -0.71 |
427.46 | 0.10 | 0.10 |
382.89 | 4.89 | 4.89 |
388.90 | 3.15 | 3.15 |
376.45 | 2.00 | 2.00 |
214.23 | -0.25 | -0.25 |
366.55 | 4.83 | 4.83 |
349.77 | 0.71 | 0.71 |
261.09 | 1.88 | 1.88 |
213.28 | 0.55 | 0.55 |
131.18 | 0.59 | 0.59 |
432.60 | 4.19 | 4.19 |
418.57 | 4.59 | 4.59 |
287.36 | 2.35 | 2.35 |
435.53 | 4.16 | 4.16 |
352.48 | 4.36 | 4.36 |
228.29 | 3.37 | 3.37 |
293.32 | 4.03 | 4.03 |
364.42 | 3.04 | 3.04 |
445.55 | 2.08 | 2.08 |
231.26 | 3.25 | 3.25 |
427.53 | 4.11 | 4.11 |
253.72 | 1.72 | 1.72 |
824.97 | 3.52 | 3.52 |
365.41 | 0.02 | 0.02 |
136.20 | 0.69 | 0.69 |
238.24 | 0.96 | 0.96 |
298.30 | 2.75 | 2.75 |
379.44 | 3.68 | 3.68 |
313.79 | 3.43 | 3.43 |
497.50 | 1.02 | 1.02 |
296.20 | -0.80 | -0.80 |
352.47 | 3.41 | 3.41 |
424.53 | 2.44 | 2.44 |
462.51 | -0.23 | -0.23 |
348.43 | 2.53 | 2.53 |
161.20 | -1.81 | -1.81 |
498.58 | 2.58 | 2.58 |
416.52 | 2.38 | 2.38 |
344.50 | 4.84 | 4.84 |
176.18 | 0.60 | 0.60 |
133.19 | 1.50 | 1.50 |
443.64 | 3.47 | 3.47 |
262.22 | 0.84 | 0.84 |
397.76 | 6.52 | 6.52 |
405.50 | 1.24 | 1.24 |
188.22 | 1.89 | 1.89 |
184.49 | 2.35 | 2.35 |
184.49 | 2.35 | 2.35 |
429.13 | 6.12 | 6.12 |
415.57 | 4.11 | 4.11 |
412.53 | 6.68 | 6.68 |
317.22 | 2.45 | 2.45 |
291.44 | 3.47 | 3.47 |
309.41 | 2.27 | 2.27 |
473.41 | 7.49 | 7.49 |
324.42 | 3.17 | 3.17 |
411.79 | 6.64 | 6.64 |
531.44 | 4.21 | 4.21 |
532.47 | 4.46 | 4.46 |
191.14 | -1.28 | -1.28 |
163.20 | -0.49 | -0.49 |
221.30 | 1.05 | 1.05 |
324.34 | -0.80 | -0.80 |
929.16 | 8.07 | 8.07 |
430.54 | 2.72 | 2.72 |
312.45 | 3.88 | 3.88 |
416.58 | 4.85 | 4.85 |
527.53 | 1.03 | 1.03 |
293.37 | 2.93 | 2.93 |
207.27 | 2.44 | 2.44 |
461.56 | 5.86 | 5.86 |
288.43 | 3.88 | 3.88 |
152.18 | 0.64 | 0.64 |
822.95 | 4.34 | 4.34 |
418.45 | 2.97 | 2.97 |
392.47 | 1.90 | 1.90 |
255.23 | -1.97 | -1.97 |
225.21 | -1.33 | -1.33 |
324.45 | 0.61 | 0.61 |
339.37 | -0.40 | -0.40 |
130.08 | -0.80 | -0.80 |
149.21 | 0.11 | 0.11 |
129.17 | -1.03 | -1.03 |
457.48 | 0.19 | 0.19 |
454.52 | -0.64 | -0.64 |
424.39 | -0.54 | -0.54 |
480.57 | -1.28 | -1.28 |
444.44 | -0.21 | -0.21 |
166.25 | 1.28 | 1.28 |
414.48 | 2.48 | 2.48 |
366.84 | 5.51 | 5.51 |
180.17 | -1.04 | -1.04 |
204.30 | 2.15 | 2.15 |
210.28 | 0.07 | 0.07 |
236.23 | -0.21 | -0.21 |
129.09 | -0.51 | -0.51 |
308.33 | 3.61 | 3.61 |
136.11 | 0.06 | 0.06 |
847.02 | 4.62 | 4.62 |
392.58 | 4.48 | 4.48 |
337.46 | 4.22 | 4.22 |
384.26 | 3.96 | 3.96 |
490.63 | 3.07 | 3.07 |
479.53 | 3.68 | 3.68 |
422.92 | 4.27 | 4.27 |
558.65 | 6.31 | 6.31 |
408.88 | 2.27 | 2.27 |
476.59 | 3.64 | 3.64 |
285.34 | 1.63 | 1.63 |
346.34 | 2.18 | 2.18 |
345.42 | 2.90 | 2.90 |
356.51 | 5.35 | 5.35 |
434.50 | 2.27 | 2.27 |
170.24 | 1.38 | 1.38 |
430.55 | 2.77 | 2.77 |
231.26 | 3.25 | 3.25 |
391.29 | 6.11 | 6.11 |
253.26 | -0.90 | -0.90 |
453.46 | -0.54 | -0.54 |
277.27 | 1.15 | 1.15 |
392.58 | 4.48 | 4.48 |
1255.44 | ||
926.11 | 0.94 | 0.94 |
217.29 | 0.63 | 0.63 |
467.65 | 4.41 | 4.41 |
645.61 | -8.56 | -8.56 |
285.24 | -1.84 | -1.84 |
656.66 | 2.75 | 2.75 |
475.59 | -3.20 | -3.20 |
440.41 | 5.18 | 5.18 |
268.27 | -1.18 | -1.18 |
465.53 | 1.30 | 1.30 |
408.92 | 2.17 | 2.17 |
438.52 | 2.57 | 2.57 |
423.47 | 0.48 | 0.48 |
542.58 | -0.92 | -0.92 |
410.43 | -0.05 | -0.05 |
575.63 | -1.40 | -1.40 |
309.41 | 0.63 | 0.63 |
512.51 | -0.04 | -0.04 |
285.69 | -0.30 | -0.30 |
244.21 | -3.01 | -3.01 |
363.39 | 0.15 | 0.15 |
371.39 | 2.58 | 2.58 |
434.50 | 2.47 | 2.47 |
351.47 | 4.43 | 4.43 |
427.46 | -0.54 | -0.54 |
645.68 | -1.11 | -1.11 |
245.37 | 3.11 | 3.11 |
791.11 | -0.41 | -0.41 |
388.42 | 3.20 | 3.20 |
347.40 | 0.44 | 0.44 |
465.95 | 3.36 | 3.36 |
455.47 | -0.62 | -0.62 |
539.59 | -0.23 | -0.23 |
778.95 | 4.75 | 4.75 |
268.27 | -2.71 | -2.71 |
747.96 | 2.44 | 2.44 |
467.52 | -6.30 | -6.30 |
138.06 | -0.09 | -0.09 |
192.26 | 1.59 | 1.59 |
274.41 | 3.51 | 3.51 |
240.30 | 0.70 | 0.70 |
414.37 | 3.05 | 3.05 |
510.48 | -0.17 | -0.17 |
337.42 | 3.59 | 3.59 |
400.60 | 6.40 | 6.40 |
341.43 | 0.28 | 0.28 |
496.58 | 3.76 | 3.76 |
504.60 | 3.82 | 3.82 |
283.33 | -1.04 | -1.04 |
387.72 | 5.86 | 5.86 |
821.14 | -1.63 | -1.63 |
386.80 | 5.03 | 5.03 |
1550.19 | ||
434.50 | 2.47 | 2.47 |
807.11 | -2.02 | -2.02 |
370.53 | 4.50 | 4.50 |
637.74 | 5.97 | 5.97 |
609.69 | 4.41 | 4.41 |
412.61 | 5.09 | 5.09 |
862.06 | 2.68 | 2.68 |
200.05 | 2.42 | 2.42 |
273.74 | 1.62 | 1.62 |
762.71 | 3.63 | 3.63 |
502.58 | 3.52 | 3.52 |
168.04 | 2.08 | 2.08 |
434.53 | 1.80 | 1.80 |
591.78 | 8.00 | 8.00 |
195.22 | 0.74 | 0.74 |
777.09 | -1.01 | -1.01 |
549.70 | 6.83 | 6.83 |
396.57 | 6.13 | 6.13 |
521.05 | 3.94 | 3.94 |
557.61 | 0.83 | 0.83 |
182.22 | -0.25 | -0.25 |
451.62 | 3.19 | 3.19 |
412.61 | 6.40 | 6.40 |
384.52 | 4.58 | 4.58 |
310.44 | 3.92 | 3.92 |
471.55 | -0.73 | -0.73 |
307.44 | 4.42 | 4.42 |
254.29 | -0.19 | -0.19 |
325.46 | 2.29 | 2.29 |
291.39 | 2.33 | 2.33 |
351.44 | 2.84 | 2.84 |
474.55 | 2.22 | 2.22 |
311.64 | 0.26 | 0.26 |
314.26 | 1.74 | 1.74 |
461.56 | 5.16 | 5.16 |
362.28 | 1.55 | 1.55 |
428.90 | 3.09 | 3.09 |
408.92 | 2.02 | 2.02 |
410.91 | 3.14 | 3.14 |
444.52 | 3.47 | 3.47 |
427.37 | 3.41 | 3.41 |
314.73 | 2.58 | 2.58 |
263.38 | 2.63 | 2.63 |
1106.14 | ||
476.87 | 0.22 | 0.22 |
476.59 | 3.64 | 3.64 |
412.37 | 2.85 | 2.85 |
420.53 | 4.89 | 4.89 |
279.38 | 3.96 | 3.96 |
265.22 | -2.89 | -2.89 |
472.58 | 3.34 | 3.34 |
651.82 | 3.04 | 3.04 |
504.60 | 3.67 | 3.67 |
518.62 | 4.21 | 4.21 |
568.56 | 0.24 | 0.24 |
528.57 | 3.92 | 3.92 |
504.60 | 3.82 | 3.82 |
384.52 | 5.18 | 5.18 |
384.56 | 6.13 | 6.13 |
788.68 | 9.41 | 9.41 |
440.67 | 7.69 | 7.69 |
484.72 | 7.53 | 7.53 |
406.57 | 5.67 | 5.67 |
314.41 | 1.46 | 1.46 |
239.27 | 1.42 | 1.42 |
1060.46 | 2.36 | 2.36 |
372.55 | 6.26 | 6.26 |
790.00 | 2.75 | 2.75 |
411.47 | 4.63 | 4.63 |
835.09 | 2.20 | 2.20 |
563.67 | 6.12 | 6.12 |
331.47 | 1.32 | 1.32 |
389.43 | 0.71 | 0.71 |
861.94 | 3.26 | 3.26 |
315.22 | -1.66 | -1.66 |
740.76 | 1.54 | 1.54 |