Basic Information
ID: ALA1697802
Type: ADME
Description: FDA HLAED, gamma-glutamyl transferase (GGT) increase
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1697802
GGT Increase - Activity Score
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.41 | 1.78 | 1.78 |
| 162.24 | 1.85 | 1.85 |
| 361.37 | 1.54 | 1.54 |
| 357.79 | 3.93 | 3.93 |
| 331.35 | 1.58 | 1.58 |
| 319.34 | 1.27 | 1.27 |
| 365.84 | 2.08 | 2.08 |
| 303.29 | 1.77 | 1.77 |
| 430.38 | 2.88 | 2.88 |
| 284.75 | 3.15 | 3.15 |
| 267.37 | 1.61 | 1.61 |
| 252.27 | 1.77 | 1.77 |
| 314.86 | 4.53 | 4.53 |
| 231.09 | 1.81 | 1.81 |
| 454.61 | 5.09 | 5.09 |
| 398.40 | 3.70 | 3.70 |
| 414.53 | 3.37 | 3.37 |
| 266.34 | 0.45 | 0.45 |
| 180.16 | 1.31 | 1.31 |
| 407.51 | 4.95 | 4.95 |
| 307.43 | 2.39 | 2.39 |
| 302.24 | 2.91 | 2.91 |
| 328.41 | 2.14 | 2.14 |
| 297.75 | -0.35 | -0.35 |
| 330.75 | 1.89 | 1.89 |
| 250.28 | 0.86 | 0.86 |
| 300.44 | 5.60 | 5.60 |
| 262.31 | 1.31 | 1.31 |
| 309.33 | 4.44 | 4.44 |
| 326.83 | 3.72 | 3.72 |
| 263.38 | 3.83 | 3.83 |
| 250.34 | 3.57 | 3.57 |
| 293.37 | 3.13 | 3.13 |
| 385.51 | 2.09 | 2.09 |
| 211.22 | 0.44 | 0.44 |
| 302.37 | 3.57 | 3.57 |
| 375.87 | 4.43 | 4.43 |
| 340.43 | 2.88 | 2.88 |
| 354.49 | 5.65 | 5.65 |
| 266.30 | 2.65 | 2.65 |
| 314.47 | 5.74 | 5.74 |
| 444.49 | -0.14 | -0.14 |
| 76.05 | -0.96 | -0.96 |
| 414.41 | 2.41 | 2.41 |
| 137.14 | -0.31 | -0.31 |
| 255.27 | 2.29 | 2.29 |
| 272.37 | 1.09 | 1.09 |
| 494.01 | 3.64 | 3.64 |
| 267.25 | -1.98 | -1.98 |
| 370.59 | 5.89 | 5.89 |
| 369.37 | 3.52 | 3.52 |
| 586.69 | 4.09 | 4.09 |
| 232.28 | 1.35 | 1.35 |
| 329.37 | 3.33 | 3.33 |
| 371.52 | 6.00 | 6.00 |
| 654.61 | 3.19 | 3.19 |
| 421.45 | 1.85 | 1.85 |
| 410.49 | 3.59 | 3.59 |
| 299.80 | 2.00 | 2.00 |
| 853.92 | 3.74 | 3.74 |
| 354.49 | 3.48 | 3.48 |
| 261.09 | 1.88 | 1.88 |
| 316.43 | 0.50 | 0.50 |
| 248.33 | 1.91 | 1.91 |
| 924.09 | 0.71 | 0.71 |
| 236.30 | 2.73 | 2.73 |
| 198.27 | 2.70 | 2.70 |
| 404.55 | 4.20 | 4.20 |
| 296.15 | 4.74 | 4.74 |
| 214.05 | 1.16 | 1.16 |
| 187.20 | 1.02 | 1.02 |
| 339.48 | 3.36 | 3.36 |
| 206.28 | 3.07 | 3.07 |
| 178.27 | 3.64 | 3.64 |
| 331.35 | 1.58 | 1.58 |
| 383.41 | -0.56 | -0.56 |
| 749.00 | 1.90 | 1.90 |
| 314.50 | 4.27 | 4.27 |
| 733.94 | 1.79 | 1.79 |
| 384.59 | 4.16 | 4.16 |
| 306.28 | 0.74 | 0.74 |
| 300.44 | 5.60 | 5.60 |
| 208.26 | 1.16 | 1.16 |
| 236.27 | 3.39 | 3.39 |
| 144.21 | 2.29 | 2.29 |
| 179.26 | 2.03 | 2.03 |
| 351.35 | 1.80 | 1.80 |
| 352.77 | 2.81 | 2.81 |
| 244.26 | 3.68 | 3.68 |
| 151.16 | 1.35 | 1.35 |
| 403.98 | 3.94 | 3.94 |
| 356.42 | 4.37 | 4.37 |
| 254.29 | 3.11 | 3.11 |
| 238.16 | 0.07 | 0.07 |
| 376.45 | 1.60 | 1.60 |
| 670.86 | 3.09 | 3.09 |
| 613.80 | 2.87 | 2.87 |
| 369.43 | 2.74 | 2.74 |
| 471.69 | 6.45 | 6.45 |
| 336.48 | 4.14 | 4.14 |
| 163.20 | -0.49 | -0.49 |
| 341.41 | 1.53 | 1.53 |
| 575.69 | 5.70 | 5.70 |
| 382.54 | 3.95 | 3.95 |
| 146.24 | -1.92 | -1.92 |
| 291.73 | 2.85 | 2.85 |
| 387.44 | 1.06 | 1.06 |
| 383.47 | -0.31 | -0.31 |
| 371.87 | 2.36 | 2.36 |
| 287.36 | 3.38 | 3.38 |
| 470.02 | 3.55 | 3.55 |
| 287.41 | 4.99 | 4.99 |
| 278.31 | 0.19 | 0.19 |
| 277.41 | 4.17 | 4.17 |
| 295.41 | 1.32 | 1.32 |
| 341.45 | 3.24 | 3.24 |
| 392.47 | 1.90 | 1.90 |
| 645.32 | 6.94 | 6.94 |
| 416.53 | 1.38 | 1.38 |
| 358.43 | 1.77 | 1.77 |
| 277.41 | 3.04 | 3.04 |
| 267.24 | -0.20 | -0.20 |
| 381.91 | 4.30 | 4.30 |
| 235.33 | 1.34 | 1.34 |
| 336.43 | 2.37 | 2.37 |
| 294.44 | 4.12 | 4.12 |
| 325.45 | 2.37 | 2.37 |
| 343.22 | 4.23 | 4.23 |
| 245.11 | 1.76 | 1.76 |
| 374.48 | 1.80 | 1.80 |
| 414.35 | 3.44 | 3.44 |
| 230.10 | 2.36 | 2.36 |
| 265.36 | 2.48 | 2.48 |
| 325.77 | 4.32 | 4.32 |
| 272.39 | 3.61 | 3.61 |
| 386.56 | 4.21 | 4.21 |
| 151.25 | 1.91 | 1.91 |
| 308.77 | 3.58 | 3.58 |
| 277.41 | 4.21 | 4.21 |
| 126.00 | -0.16 | -0.16 |
| 171.16 | 0.09 | 0.09 |
| 275.40 | 4.55 | 4.55 |
| 189.22 | 0.16 | 0.16 |
| 367.81 | 0.62 | 0.62 |
| 244.29 | 2.67 | 2.67 |
| 295.30 | 2.97 | 2.97 |
| 296.15 | 4.36 | 4.36 |
| 241.29 | 3.75 | 3.75 |
| 143.14 | 0.37 | 0.37 |
| 213.66 | 1.86 | 1.86 |
| 517.56 | -0.24 | -0.24 |
| 153.14 | 0.67 | 0.67 |
| 451.48 | 1.72 | 1.72 |
| 372.55 | 3.81 | 3.81 |
| 229.26 | -0.59 | -0.59 |
| 239.31 | 1.31 | 1.31 |
| 312.44 | 3.44 | 3.44 |
| 386.53 | 4.66 | 4.66 |
| 500.63 | 2.59 | 2.59 |
| 406.48 | 3.74 | 3.74 |
| 437.53 | 4.31 | 4.31 |
| 167.20 | 0.60 | 0.60 |
| 75.07 | -0.49 | -0.49 |
| 256.10 | 2.01 | 2.01 |
| 234.20 | 2.78 | 2.78 |
| 371.35 | 2.48 | 2.48 |
| 376.50 | 5.12 | 5.12 |
| 295.38 | 1.53 | 1.53 |
| 327.47 | 3.37 | 3.37 |
| 294.75 | 3.27 | 3.27 |
| 454.45 | 0.27 | 0.27 |
| 209.25 | -0.13 | -0.13 |
| 230.26 | 3.04 | 3.04 |
| 378.32 | 4.45 | 4.45 |
| 243.22 | -2.56 | -2.56 |
| 276.21 | 3.21 | 3.21 |
| 381.69 | 5.80 | 5.80 |
| 306.24 | 5.18 | 5.18 |
| 312.42 | 2.32 | 2.32 |
| 318.34 | 3.20 | 3.20 |
| 246.31 | -0.28 | -0.28 |
| 291.44 | 4.88 | 4.88 |
| 320.32 | 0.66 | 0.66 |
| 327.81 | 3.77 | 3.77 |
| 263.79 | 3.96 | 3.96 |
| 235.07 | -1.66 | -1.66 |
| 435.44 | -1.17 | -1.17 |
| 546.59 | -1.30 | -1.30 |
| 424.50 | 2.57 | 2.57 |
| 292.38 | 1.70 | 1.70 |
| 292.14 | 1.76 | 1.76 |
| 416.65 | 5.70 | 5.70 |
| 392.41 | 2.08 | 2.08 |
| 305.21 | 1.93 | 1.93 |
| 211.22 | -0.50 | -0.50 |
| 458.58 | 5.35 | 5.35 |
| 218.26 | 0.54 | 0.54 |
| 246.10 | 1.55 | 1.55 |
| 204.31 | -0.29 | -0.29 |
| 320.34 | 2.73 | 2.73 |
| 588.56 | 1.34 | 1.34 |
| 249.10 | -1.27 | -1.27 |
| 206.03 | -0.99 | -0.99 |
| 321.34 | 0.54 | 0.54 |
| 263.20 | -1.29 | -1.29 |
| 239.75 | 3.30 | 3.30 |
| 357.45 | 1.71 | 1.71 |
| 374.91 | 3.06 | 3.06 |
| 285.37 | 2.20 | 2.20 |
| 250.20 | 3.04 | 3.04 |
| 337.46 | -0.77 | -0.77 |
| 543.53 | 0.00 | 0.00 |
| 307.40 | 3.25 | 3.25 |
| 501.67 | 5.51 | 5.51 |
| 246.19 | -1.68 | -1.68 |
| 554.59 | -1.20 | -1.20 |
| 301.39 | 2.96 | 2.96 |
| 197.38 | 2.51 | 2.51 |
| 720.96 | 5.91 | 5.91 |
| 171.24 | 1.37 | 1.37 |
| 405.97 | 6.56 | 6.56 |
| 260.31 | 3.17 | 3.17 |
| 179.31 | 2.55 | 2.55 |
| 296.55 | 3.62 | 3.62 |
| 300.75 | 2.47 | 2.47 |
| 324.81 | 3.93 | 3.93 |
| 352.74 | 4.09 | 4.09 |
| 187.29 | 2.18 | 2.18 |
| 164.18 | -0.20 | -0.20 |
| 705.65 | 5.58 | 5.58 |
| 312.41 | 2.53 | 2.53 |
| 339.44 | 2.51 | 2.51 |
| 1100.18 | ||
| 317.48 | 5.77 | 5.77 |
| 224.22 | -0.71 | -0.71 |
| 427.46 | 0.10 | 0.10 |
| 382.89 | 4.89 | 4.89 |
| 388.90 | 3.15 | 3.15 |
| 376.45 | 2.00 | 2.00 |
| 214.23 | -0.25 | -0.25 |
| 366.55 | 4.83 | 4.83 |
| 349.77 | 0.71 | 0.71 |
| 261.09 | 1.88 | 1.88 |
| 213.28 | 0.55 | 0.55 |
| 131.18 | 0.59 | 0.59 |
| 432.60 | 4.19 | 4.19 |
| 418.57 | 4.59 | 4.59 |
| 287.36 | 2.35 | 2.35 |
| 435.53 | 4.16 | 4.16 |
| 352.48 | 4.36 | 4.36 |
| 228.29 | 3.37 | 3.37 |
| 293.32 | 4.03 | 4.03 |
| 364.42 | 3.04 | 3.04 |
| 445.55 | 2.08 | 2.08 |
| 231.26 | 3.25 | 3.25 |
| 427.53 | 4.11 | 4.11 |
| 253.72 | 1.72 | 1.72 |
| 824.97 | 3.52 | 3.52 |
| 365.41 | 0.02 | 0.02 |
| 136.20 | 0.69 | 0.69 |
| 238.24 | 0.96 | 0.96 |
| 298.30 | 2.75 | 2.75 |
| 379.44 | 3.68 | 3.68 |
| 313.79 | 3.43 | 3.43 |
| 497.50 | 1.02 | 1.02 |
| 296.20 | -0.80 | -0.80 |
| 352.47 | 3.41 | 3.41 |
| 424.53 | 2.44 | 2.44 |
| 462.51 | -0.23 | -0.23 |
| 348.43 | 2.53 | 2.53 |
| 161.20 | -1.81 | -1.81 |
| 498.58 | 2.58 | 2.58 |
| 416.52 | 2.38 | 2.38 |
| 344.50 | 4.84 | 4.84 |
| 176.18 | 0.60 | 0.60 |
| 133.19 | 1.50 | 1.50 |
| 443.64 | 3.47 | 3.47 |
| 262.22 | 0.84 | 0.84 |
| 397.76 | 6.52 | 6.52 |
| 405.50 | 1.24 | 1.24 |
| 188.22 | 1.89 | 1.89 |
| 184.49 | 2.35 | 2.35 |
| 184.49 | 2.35 | 2.35 |
| 429.13 | 6.12 | 6.12 |
| 415.57 | 4.11 | 4.11 |
| 412.53 | 6.68 | 6.68 |
| 317.22 | 2.45 | 2.45 |
| 291.44 | 3.47 | 3.47 |
| 309.41 | 2.27 | 2.27 |
| 473.41 | 7.49 | 7.49 |
| 324.42 | 3.17 | 3.17 |
| 411.79 | 6.64 | 6.64 |
| 531.44 | 4.21 | 4.21 |
| 532.47 | 4.46 | 4.46 |
| 191.14 | -1.28 | -1.28 |
| 163.20 | -0.49 | -0.49 |
| 221.30 | 1.05 | 1.05 |
| 324.34 | -0.80 | -0.80 |
| 929.16 | 8.07 | 8.07 |
| 430.54 | 2.72 | 2.72 |
| 312.45 | 3.88 | 3.88 |
| 416.58 | 4.85 | 4.85 |
| 527.53 | 1.03 | 1.03 |
| 293.37 | 2.93 | 2.93 |
| 207.27 | 2.44 | 2.44 |
| 461.56 | 5.86 | 5.86 |
| 288.43 | 3.88 | 3.88 |
| 152.18 | 0.64 | 0.64 |
| 822.95 | 4.34 | 4.34 |
| 418.45 | 2.97 | 2.97 |
| 392.47 | 1.90 | 1.90 |
| 255.23 | -1.97 | -1.97 |
| 225.21 | -1.33 | -1.33 |
| 324.45 | 0.61 | 0.61 |
| 339.37 | -0.40 | -0.40 |
| 130.08 | -0.80 | -0.80 |
| 149.21 | 0.11 | 0.11 |
| 129.17 | -1.03 | -1.03 |
| 457.48 | 0.19 | 0.19 |
| 454.52 | -0.64 | -0.64 |
| 424.39 | -0.54 | -0.54 |
| 480.57 | -1.28 | -1.28 |
| 444.44 | -0.21 | -0.21 |
| 166.25 | 1.28 | 1.28 |
| 414.48 | 2.48 | 2.48 |
| 366.84 | 5.51 | 5.51 |
| 180.17 | -1.04 | -1.04 |
| 204.30 | 2.15 | 2.15 |
| 210.28 | 0.07 | 0.07 |
| 236.23 | -0.21 | -0.21 |
| 129.09 | -0.51 | -0.51 |
| 308.33 | 3.61 | 3.61 |
| 136.11 | 0.06 | 0.06 |
| 847.02 | 4.62 | 4.62 |
| 392.58 | 4.48 | 4.48 |
| 337.46 | 4.22 | 4.22 |
| 384.26 | 3.96 | 3.96 |
| 490.63 | 3.07 | 3.07 |
| 479.53 | 3.68 | 3.68 |
| 422.92 | 4.27 | 4.27 |
| 558.65 | 6.31 | 6.31 |
| 408.88 | 2.27 | 2.27 |
| 476.59 | 3.64 | 3.64 |
| 285.34 | 1.63 | 1.63 |
| 346.34 | 2.18 | 2.18 |
| 345.42 | 2.90 | 2.90 |
| 356.51 | 5.35 | 5.35 |
| 434.50 | 2.27 | 2.27 |
| 170.24 | 1.38 | 1.38 |
| 430.55 | 2.77 | 2.77 |
| 231.26 | 3.25 | 3.25 |
| 391.29 | 6.11 | 6.11 |
| 253.26 | -0.90 | -0.90 |
| 453.46 | -0.54 | -0.54 |
| 277.27 | 1.15 | 1.15 |
| 392.58 | 4.48 | 4.48 |
| 1255.44 | ||
| 926.11 | 0.94 | 0.94 |
| 217.29 | 0.63 | 0.63 |
| 467.65 | 4.41 | 4.41 |
| 645.61 | -8.56 | -8.56 |
| 285.24 | -1.84 | -1.84 |
| 656.66 | 2.75 | 2.75 |
| 475.59 | -3.20 | -3.20 |
| 440.41 | 5.18 | 5.18 |
| 268.27 | -1.18 | -1.18 |
| 465.53 | 1.30 | 1.30 |
| 408.92 | 2.17 | 2.17 |
| 438.52 | 2.57 | 2.57 |
| 423.47 | 0.48 | 0.48 |
| 542.58 | -0.92 | -0.92 |
| 410.43 | -0.05 | -0.05 |
| 575.63 | -1.40 | -1.40 |
| 309.41 | 0.63 | 0.63 |
| 512.51 | -0.04 | -0.04 |
| 285.69 | -0.30 | -0.30 |
| 244.21 | -3.01 | -3.01 |
| 363.39 | 0.15 | 0.15 |
| 371.39 | 2.58 | 2.58 |
| 434.50 | 2.47 | 2.47 |
| 351.47 | 4.43 | 4.43 |
| 427.46 | -0.54 | -0.54 |
| 645.68 | -1.11 | -1.11 |
| 245.37 | 3.11 | 3.11 |
| 791.11 | -0.41 | -0.41 |
| 388.42 | 3.20 | 3.20 |
| 347.40 | 0.44 | 0.44 |
| 465.95 | 3.36 | 3.36 |
| 455.47 | -0.62 | -0.62 |
| 539.59 | -0.23 | -0.23 |
| 778.95 | 4.75 | 4.75 |
| 268.27 | -2.71 | -2.71 |
| 747.96 | 2.44 | 2.44 |
| 467.52 | -6.30 | -6.30 |
| 138.06 | -0.09 | -0.09 |
| 192.26 | 1.59 | 1.59 |
| 274.41 | 3.51 | 3.51 |
| 240.30 | 0.70 | 0.70 |
| 414.37 | 3.05 | 3.05 |
| 510.48 | -0.17 | -0.17 |
| 337.42 | 3.59 | 3.59 |
| 400.60 | 6.40 | 6.40 |
| 341.43 | 0.28 | 0.28 |
| 496.58 | 3.76 | 3.76 |
| 504.60 | 3.82 | 3.82 |
| 283.33 | -1.04 | -1.04 |
| 387.72 | 5.86 | 5.86 |
| 821.14 | -1.63 | -1.63 |
| 386.80 | 5.03 | 5.03 |
| 1550.19 | ||
| 434.50 | 2.47 | 2.47 |
| 807.11 | -2.02 | -2.02 |
| 370.53 | 4.50 | 4.50 |
| 637.74 | 5.97 | 5.97 |
| 609.69 | 4.41 | 4.41 |
| 412.61 | 5.09 | 5.09 |
| 862.06 | 2.68 | 2.68 |
| 200.05 | 2.42 | 2.42 |
| 273.74 | 1.62 | 1.62 |
| 762.71 | 3.63 | 3.63 |
| 502.58 | 3.52 | 3.52 |
| 168.04 | 2.08 | 2.08 |
| 434.53 | 1.80 | 1.80 |
| 591.78 | 8.00 | 8.00 |
| 195.22 | 0.74 | 0.74 |
| 777.09 | -1.01 | -1.01 |
| 549.70 | 6.83 | 6.83 |
| 396.57 | 6.13 | 6.13 |
| 521.05 | 3.94 | 3.94 |
| 557.61 | 0.83 | 0.83 |
| 182.22 | -0.25 | -0.25 |
| 451.62 | 3.19 | 3.19 |
| 412.61 | 6.40 | 6.40 |
| 384.52 | 4.58 | 4.58 |
| 310.44 | 3.92 | 3.92 |
| 471.55 | -0.73 | -0.73 |
| 307.44 | 4.42 | 4.42 |
| 254.29 | -0.19 | -0.19 |
| 325.46 | 2.29 | 2.29 |
| 291.39 | 2.33 | 2.33 |
| 351.44 | 2.84 | 2.84 |
| 474.55 | 2.22 | 2.22 |
| 311.64 | 0.26 | 0.26 |
| 314.26 | 1.74 | 1.74 |
| 461.56 | 5.16 | 5.16 |
| 362.28 | 1.55 | 1.55 |
| 428.90 | 3.09 | 3.09 |
| 408.92 | 2.02 | 2.02 |
| 410.91 | 3.14 | 3.14 |
| 444.52 | 3.47 | 3.47 |
| 427.37 | 3.41 | 3.41 |
| 314.73 | 2.58 | 2.58 |
| 263.38 | 2.63 | 2.63 |
| 1106.14 | ||
| 476.87 | 0.22 | 0.22 |
| 476.59 | 3.64 | 3.64 |
| 412.37 | 2.85 | 2.85 |
| 420.53 | 4.89 | 4.89 |
| 279.38 | 3.96 | 3.96 |
| 265.22 | -2.89 | -2.89 |
| 472.58 | 3.34 | 3.34 |
| 651.82 | 3.04 | 3.04 |
| 504.60 | 3.67 | 3.67 |
| 518.62 | 4.21 | 4.21 |
| 568.56 | 0.24 | 0.24 |
| 528.57 | 3.92 | 3.92 |
| 504.60 | 3.82 | 3.82 |
| 384.52 | 5.18 | 5.18 |
| 384.56 | 6.13 | 6.13 |
| 788.68 | 9.41 | 9.41 |
| 440.67 | 7.69 | 7.69 |
| 484.72 | 7.53 | 7.53 |
| 406.57 | 5.67 | 5.67 |
| 314.41 | 1.46 | 1.46 |
| 239.27 | 1.42 | 1.42 |
| 1060.46 | 2.36 | 2.36 |
| 372.55 | 6.26 | 6.26 |
| 790.00 | 2.75 | 2.75 |
| 411.47 | 4.63 | 4.63 |
| 835.09 | 2.20 | 2.20 |
| 563.67 | 6.12 | 6.12 |
| 331.47 | 1.32 | 1.32 |
| 389.43 | 0.71 | 0.71 |
| 861.94 | 3.26 | 3.26 |
| 315.22 | -1.66 | -1.66 |
| 740.76 | 1.54 | 1.54 |