Basic Information
ID: ALA1737868
Type: Functional
Description: PUBCHEM_BIOASSAY: Validation screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493143, AID504466]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1737868
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 317.18 | 4.50 | 4.50 |
| 383.41 | 1.78 | 1.78 |
| 246.19 | -1.69 | -1.69 |
| 430.38 | 2.88 | 2.88 |
| 314.86 | 4.53 | 4.53 |
| 407.51 | 4.95 | 4.95 |
| 270.24 | 2.58 | 2.58 |
| 326.83 | 3.54 | 3.54 |
| 399.97 | 5.97 | 5.97 |
| 393.47 | 4.51 | 4.51 |
| 305.21 | 1.93 | 1.93 |
| 270.24 | 2.58 | 2.58 |
| 329.36 | 4.06 | 4.06 |
| 168.15 | -0.14 | -0.14 |
| 196.20 | 0.64 | 0.64 |
| 214.22 | 0.73 | 0.73 |
| 254.24 | 2.87 | 2.87 |
| 361.53 | 4.84 | 4.84 |
| 444.49 | -0.14 | -0.14 |
| 348.36 | 2.08 | 2.08 |
| 301.33 | 3.03 | 3.03 |
| 1202.63 | ||
| 376.50 | 4.72 | 4.72 |
| 654.61 | 3.19 | 3.19 |
| 380.49 | 6.09 | 6.09 |
| 440.42 | 0.24 | 0.24 |
| 160.18 | 0.92 | 0.92 |
| 414.41 | 2.41 | 2.41 |
| 103.12 | -0.19 | -0.19 |
| 287.41 | 4.70 | 4.70 |
| 174.26 | 0.23 | 0.23 |
| 332.34 | 3.43 | 3.43 |
| 348.38 | 3.72 | 3.72 |
| 314.47 | 4.72 | 4.72 |
| 344.85 | 5.38 | 5.38 |
| 394.86 | 5.13 | 5.13 |
| 399.44 | 2.87 | 2.87 |
| 283.26 | 3.06 | 3.06 |
| 270.33 | 3.01 | 3.01 |
| 238.33 | 2.85 | 2.85 |
| 253.27 | 0.83 | 0.83 |
| 285.69 | 2.77 | 2.77 |
| 345.37 | 2.56 | 2.56 |
| 360.35 | 4.85 | 4.85 |
| 471.69 | 6.45 | 6.45 |
| 371.40 | 0.36 | 0.36 |
| 246.31 | 4.49 | 4.49 |
| 450.57 | 5.32 | 5.32 |
| 502.77 | 7.28 | 7.28 |
| 231.04 | 2.35 | 2.35 |
| 275.40 | 4.55 | 4.55 |
| 353.51 | 4.66 | 4.66 |
| 414.59 | 5.04 | 5.04 |
| 406.48 | 3.74 | 3.74 |
| 373.95 | 4.58 | 4.58 |
| 234.20 | 2.78 | 2.78 |
| 550.76 | 5.98 | 5.98 |
| 522.71 | 5.20 | 5.20 |
| 347.86 | 4.47 | 4.47 |
| 472.09 | 8.01 | 8.01 |
| 542.42 | 4.16 | 4.16 |
| 434.52 | 3.70 | 3.70 |
| 422.57 | 3.83 | 3.83 |
| 395.47 | 4.23 | 4.23 |
| 454.45 | 0.27 | 0.27 |
| 267.28 | 3.05 | 3.05 |
| 342.44 | 3.48 | 3.48 |
| 276.21 | 3.21 | 3.21 |
| 306.24 | 5.18 | 5.18 |
| 180.21 | 2.78 | 2.78 |
| 258.28 | 1.55 | 1.55 |
| 477.05 | 5.09 | 5.09 |
| 292.34 | 3.17 | 3.17 |
| 338.21 | 4.10 | 4.10 |
| 434.20 | 6.77 | 6.77 |
| 370.46 | 5.59 | 5.59 |
| 495.64 | 5.27 | 5.27 |
| 365.84 | 2.71 | 2.71 |
| 336.44 | 2.75 | 2.75 |
| 480.65 | 4.94 | 4.94 |
| 327.18 | 4.09 | 4.09 |
| 225.25 | 2.03 | 2.03 |
| 434.53 | 4.60 | 4.60 |
| 390.52 | 3.95 | 3.95 |
| 308.31 | 2.76 | 2.76 |
| 308.34 | 2.36 | 2.36 |
| 270.21 | 3.25 | 3.25 |
| 296.55 | 3.62 | 3.62 |
| 291.44 | 4.56 | 4.56 |
| 351.86 | 2.69 | 2.69 |
| 331.80 | 3.33 | 3.33 |
| 193.25 | 2.79 | 2.79 |
| 203.25 | 1.52 | 1.52 |
| 436.62 | 7.51 | 7.51 |
| 228.25 | 2.97 | 2.97 |
| 325.45 | 3.77 | 3.77 |
| 244.25 | 2.68 | 2.68 |
| 335.36 | -0.21 | -0.21 |
| 382.89 | 4.89 | 4.89 |
| 469.67 | 7.22 | 7.22 |
| 251.29 | 2.00 | 2.00 |
| 385.51 | 1.20 | 1.20 |
| 282.39 | 4.42 | 4.42 |
| 287.32 | 3.10 | 3.10 |
| 316.33 | 3.79 | 3.79 |
| 253.72 | 1.72 | 1.72 |
| 264.33 | 3.25 | 3.25 |
| 195.26 | 3.56 | 3.56 |
| 213.24 | 3.51 | 3.51 |
| 303.41 | 4.89 | 4.89 |
| 136.20 | 0.69 | 0.69 |
| 650.76 | 3.93 | 3.93 |
| 286.36 | 3.59 | 3.59 |
| 356.56 | 4.40 | 4.40 |
| 291.38 | 1.22 | 1.22 |
| 497.50 | 1.02 | 1.02 |
| 118.16 | -0.22 | -0.22 |
| 309.49 | 4.40 | 4.40 |
| 371.22 | 4.05 | 4.05 |
| 284.31 | 2.90 | 2.90 |
| 130.22 | 0.83 | 0.83 |
| 327.34 | 3.05 | 3.05 |
| 523.74 | 6.49 | 6.49 |
| 456.68 | 6.17 | 6.17 |
| 317.43 | 3.24 | 3.24 |
| 510.29 | 0.41 | 0.41 |
| 386.41 | -0.33 | -0.33 |
| 304.35 | 3.84 | 3.84 |
| 212.21 | 1.31 | 1.31 |
| 604.70 | 3.54 | 3.54 |
| 277.28 | 4.42 | 4.42 |
| 256.26 | 2.70 | 2.70 |
| 385.42 | 0.48 | 0.48 |
| 416.95 | 4.61 | 4.61 |
| 392.50 | 3.41 | 3.41 |
| 265.34 | 0.73 | 0.73 |
| 292.21 | 4.79 | 4.79 |
| 139.18 | -0.78 | -0.78 |
| 531.44 | 4.21 | 4.21 |
| 356.18 | 5.18 | 5.18 |
| 385.90 | 3.93 | 3.93 |
| 434.71 | 4.01 | 4.01 |
| 345.47 | 3.94 | 3.94 |
| 592.69 | 2.88 | 2.88 |
| 244.24 | 3.42 | 3.42 |
| 279.10 | -0.20 | -0.20 |
| 337.42 | 4.41 | 4.41 |
| 281.27 | -1.52 | -1.52 |
| 395.42 | 2.53 | 2.53 |
| 305.29 | 3.12 | 3.12 |
| 305.73 | 1.07 | 1.07 |
| 478.55 | 5.18 | 5.18 |
| 130.08 | -0.80 | -0.80 |
| 307.10 | -1.06 | -1.06 |
| 584.66 | -1.51 | -1.51 |
| 433.72 | 4.61 | 4.61 |
| 476.79 | 4.68 | 4.68 |
| 451.68 | 5.28 | 5.28 |
| 362.47 | 1.78 | 1.78 |
| 426.52 | 4.60 | 4.60 |
| 396.83 | 3.76 | 3.76 |
| 276.68 | 3.50 | 3.50 |
| 479.53 | 3.68 | 3.68 |
| 417.63 | 6.79 | 6.79 |
| 244.21 | -3.17 | -3.17 |
| 611.74 | 6.48 | 6.48 |
| 346.34 | 2.18 | 2.18 |
| 147.27 | 1.30 | 1.30 |
| 452.46 | 2.74 | 2.74 |
| 361.40 | 0.02 | 0.02 |
| 343.34 | 0.18 | 0.18 |
| 395.54 | 4.55 | 4.55 |
| 241.25 | 1.91 | 1.91 |
| 343.43 | 4.69 | 4.69 |
| 207.25 | 1.81 | 1.81 |
| 241.25 | 1.51 | 1.51 |
| 249.34 | 2.80 | 2.80 |
| 492.53 | 4.28 | 4.28 |
| 360.44 | 4.55 | 4.55 |
| 308.30 | -1.84 | -1.84 |
| 343.90 | 5.10 | 5.10 |
| 264.13 | 2.99 | 2.99 |
| 220.25 | 1.29 | 1.29 |
| 311.34 | 3.21 | 3.21 |
| 285.40 | 3.33 | 3.33 |
| 376.58 | 5.66 | 5.66 |
| 316.47 | 4.18 | 4.18 |
| 496.68 | 3.80 | 3.80 |
| 490.65 | 3.87 | 3.87 |
| 257.27 | 1.95 | 1.95 |
| 260.34 | 1.80 | 1.80 |
| 361.53 | 5.53 | 5.53 |
| 193.16 | 1.66 | 1.66 |
| 371.46 | 2.64 | 2.64 |
| 399.41 | -0.61 | -0.61 |
| 452.56 | 3.91 | 3.91 |
| 328.36 | 4.43 | 4.43 |
| 267.36 | 3.13 | 3.13 |
| 652.26 | 10.29 | 10.29 |
| 285.23 | 2.33 | 2.33 |
| 181.22 | 0.28 | 0.28 |
| 231.08 | 2.66 | 2.66 |
| 277.21 | 2.38 | 2.38 |
| 235.34 | 2.95 | 2.95 |
| 358.36 | -0.24 | -0.24 |
| 523.63 | 5.53 | 5.53 |
| 398.42 | 2.91 | 2.91 |
| 429.60 | 5.41 | 5.41 |
| 404.43 | 2.96 | 2.96 |
| 366.46 | 4.15 | 4.15 |
| 491.65 | 5.96 | 5.96 |
| 198.23 | 1.87 | 1.87 |
| 410.51 | 1.52 | 1.52 |
| 287.75 | 4.00 | 4.00 |
| 541.63 | -0.98 | -0.98 |
| 438.58 | 5.32 | 5.32 |
| 467.42 | 3.81 | 3.81 |
| 139.15 | 0.28 | 0.28 |
| 824.97 | 3.52 | 3.52 |
| 481.48 | 3.98 | 3.98 |
| 394.49 | 4.04 | 4.04 |
| 357.23 | 4.39 | 4.39 |
| 220.28 | 3.48 | 3.48 |
| 810.99 | 3.99 | 3.99 |
| 473.30 | -1.02 | -1.02 |
| 355.50 | 4.51 | 4.51 |
| 365.84 | 2.98 | 2.98 |
| 268.32 | 2.72 | 2.72 |
| 416.58 | 4.85 | 4.85 |
| 586.68 | -1.44 | -1.44 |
| 419.35 | 3.74 | 3.74 |
| 230.68 | 1.90 | 1.90 |
| 337.46 | 4.22 | 4.22 |
| 508.45 | 5.68 | 5.68 |
| 272.39 | 4.64 | 4.64 |
| 280.36 | 2.11 | 2.11 |
| 310.46 | 5.07 | 5.07 |
| 351.36 | -1.24 | -1.24 |
| 375.17 | -0.39 | -0.39 |
| 448.55 | 0.94 | 0.94 |
| 471.82 | 1.99 | 1.99 |
| 616.84 | 5.75 | 5.75 |
| 392.50 | 2.39 | 2.39 |
| 875.11 | 5.60 | 5.60 |