Basic Information
ID: ALA1737951
Type: Functional
Description: PUBCHEM_BIOASSAY: Confirmation assay for inhibitors of Trypanosoma brucei hexokinase 1-Analogue-first series. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1430, AID1632, AID2516, AID2560, AID2579, AID2600, AID449725, AID492951]
Organism: Trypanosoma brucei
Activity Charts
Bioactivity
Activity Types for Assay ALA1737951
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 302.24 | 1.99 | 1.99 |
| 209.20 | 0.51 | 0.51 |
| 663.08 | 7.12 | 7.12 |
| 227.29 | 3.05 | 3.05 |
| 271.27 | 2.65 | 2.65 |
| 228.28 | 2.45 | 2.45 |
| 257.31 | 3.06 | 3.06 |
| 261.73 | 3.71 | 3.71 |
| 177.23 | 1.90 | 1.90 |
| 201.94 | ||
| 319.74 | 3.39 | 3.39 |
| 324.16 | 4.03 | 4.03 |
| 319.74 | 3.39 | 3.39 |
| 191.25 | 2.21 | 2.21 |
| 253.33 | 3.57 | 3.57 |
| 251.05 | ||
| 223.28 | 3.84 | 3.84 |
| 259.31 | 3.50 | 3.50 |
| 241.32 | 3.36 | 3.36 |
| 334.42 | 2.30 | 2.30 |
| 305.72 | 3.30 | 3.30 |
| 305.72 | 3.30 | 3.30 |
| 245.28 | 3.19 | 3.19 |
| 319.74 | 3.23 | 3.23 |
| 329.78 | 4.34 | 4.34 |
| 261.73 | 3.71 | 3.71 |
| 343.69 | 4.31 | 4.31 |
| 340.79 | 2.25 | 2.25 |
| 279.72 | 3.84 | 3.84 |
| 296.18 | 4.36 | 4.36 |
| 303.79 | 4.60 | 4.60 |
| 275.69 | 3.29 | 3.29 |
| 312.39 | 2.72 | 2.72 |
| 305.72 | 3.30 | 3.30 |
| 289.72 | 3.60 | 3.60 |
| 272.29 | 2.96 | 2.96 |
| 289.72 | 3.60 | 3.60 |
| 279.72 | 3.84 | 3.84 |
| 271.27 | 2.65 | 2.65 |
| 352.34 | 3.72 | 3.72 |
| 410.70 | 5.35 | 5.35 |
| 252.30 | 2.92 | 2.92 |
| 303.75 | 3.91 | 3.91 |
| 245.28 | 3.19 | 3.19 |
| 272.29 | 2.96 | 2.96 |
| 245.28 | 3.19 | 3.19 |
| 270.31 | 3.14 | 3.14 |
| 252.30 | 2.92 | 2.92 |
| 298.37 | 2.38 | 2.38 |
| 276.36 | 2.08 | 2.08 |
| 347.37 | 4.31 | 4.31 |
| 302.33 | 2.84 | 2.84 |
| 397.17 | 3.25 | 3.25 |
| 300.31 | 2.52 | 2.52 |
| 286.72 | 3.47 | 3.47 |
| 295.30 | 2.13 | 2.13 |
| 298.37 | 3.26 | 3.26 |
| 355.80 | 2.94 | 2.94 |
| 363.24 | 3.46 | 3.46 |
| 318.79 | 3.36 | 3.36 |
| 315.76 | 3.78 | 3.78 |
| 333.77 | 3.29 | 3.29 |
| 247.29 | 3.37 | 3.37 |
| 363.24 | 3.46 | 3.46 |
| 341.77 | 2.85 | 2.85 |
| 284.34 | 3.01 | 3.01 |
| 283.71 | 2.40 | 2.40 |
| 319.74 | 3.32 | 3.32 |
| 319.74 | 3.39 | 3.39 |
| 319.74 | 3.69 | 3.69 |
| 315.76 | 4.32 | 4.32 |
| 224.26 | 2.33 | 2.33 |
| 410.24 | 3.31 | 3.31 |
| 327.41 | 2.77 | 2.77 |
| 261.28 | 2.86 | 2.86 |
| 302.33 | 2.84 | 2.84 |
| 259.31 | 3.25 | 3.25 |
| 329.75 | 2.78 | 2.78 |
| 366.24 | 5.24 | 5.24 |
| 340.16 | 3.95 | 3.95 |
| 302.33 | 2.84 | 2.84 |
| 325.75 | 4.44 | 4.44 |
| 306.71 | 3.51 | 3.51 |
| 284.34 | 2.70 | 2.70 |
| 165.22 | 1.60 | 1.60 |
| 384.61 | 4.06 | 4.06 |
| 318.79 | 3.36 | 3.36 |
| 309.35 | 2.57 | 2.57 |
| 376.25 | 4.70 | 4.70 |
| 301.30 | 2.65 | 2.65 |
| 352.34 | 3.72 | 3.72 |
| 331.80 | 4.49 | 4.49 |
| 284.34 | 3.01 | 3.01 |
| 319.70 | 3.02 | 3.02 |
| 306.18 | 3.81 | 3.81 |
| 350.17 | 3.41 | 3.41 |
| 257.31 | 3.06 | 3.06 |
| 306.71 | 2.69 | 2.69 |
| 277.71 | 3.31 | 3.31 |
| 312.39 | 2.89 | 2.89 |
| 263.27 | 3.33 | 3.33 |
| 318.76 | 3.36 | 3.36 |
| 302.33 | 2.84 | 2.84 |
| 351.79 | 4.96 | 4.96 |
| 213.62 | 2.00 | 2.00 |
| 366.24 | 5.24 | 5.24 |
| 303.75 | 3.91 | 3.91 |
| 285.30 | 2.95 | 2.95 |
| 285.25 | 2.34 | 2.34 |
| 289.26 | 2.78 | 2.78 |
| 305.72 | 3.30 | 3.30 |
| 335.02 | 3.42 | 3.42 |
| 341.84 | 4.87 | 4.87 |
| 327.41 | 2.77 | 2.77 |
| 306.18 | 3.81 | 3.81 |
| 333.77 | 3.29 | 3.29 |
| 305.72 | 3.30 | 3.30 |
| 273.33 | 3.81 | 3.81 |
| 357.82 | 5.02 | 5.02 |
| 315.76 | 4.17 | 4.17 |
| 365.82 | 4.88 | 4.88 |
| 151.19 | 1.59 | 1.59 |
| 277.73 | 3.37 | 3.37 |
| 320.21 | 4.16 | 4.16 |
| 331.80 | 4.59 | 4.59 |
| 317.77 | 4.24 | 4.24 |
| 348.20 | 3.96 | 3.96 |
| 303.75 | 3.85 | 3.85 |
| 317.73 | 3.21 | 3.21 |
| 298.37 | 3.01 | 3.01 |
| 265.65 | 2.88 | 2.88 |
| 349.79 | 4.73 | 4.73 |
| 276.68 | 2.69 | 2.69 |
| 359.69 | 4.19 | 4.19 |
| 284.34 | 2.82 | 2.82 |
| 257.31 | 3.06 | 3.06 |
| 211.22 | 2.58 | 2.58 |
| 305.72 | 3.30 | 3.30 |
| 355.83 | 4.07 | 4.07 |
| 286.29 | 3.04 | 3.04 |
| 410.24 | 3.31 | 3.31 |
| 257.31 | 3.06 | 3.06 |
| 321.31 | 2.64 | 2.64 |
| 283.75 | 3.95 | 3.95 |
| 284.70 | 1.90 | 1.90 |
| 298.37 | 3.09 | 3.09 |
| 261.71 | 3.60 | 3.60 |
| 305.72 | 3.30 | 3.30 |
| 266.64 | 2.28 | 2.28 |
| 237.28 | 1.63 | 1.63 |
| 363.24 | 3.46 | 3.46 |
| 314.37 | 2.71 | 2.71 |
| 349.46 | 5.24 | 5.24 |
| 317.77 | 4.41 | 4.41 |
| 317.77 | 4.41 | 4.41 |
| 281.72 | 3.35 | 3.35 |
| 410.24 | 3.31 | 3.31 |
| 319.74 | 3.23 | 3.23 |
| 319.74 | 3.61 | 3.61 |
| 314.37 | 2.71 | 2.71 |
| 365.77 | 3.32 | 3.32 |
| 314.37 | 2.71 | 2.71 |
| 295.29 | 4.07 | 4.07 |
| 290.39 | 2.51 | 2.51 |
| 223.28 | 3.16 | 3.16 |
| 310.14 | 3.94 | 3.94 |
| 285.30 | 2.25 | 2.25 |
| 255.30 | 2.75 | 2.75 |
| 287.70 | 3.15 | 3.15 |
| 296.71 | 2.24 | 2.24 |
| 277.71 | 3.79 | 3.79 |
| 297.78 | 4.34 | 4.34 |
| 261.73 | 3.71 | 3.71 |
| 305.72 | 3.30 | 3.30 |
| 306.18 | 3.81 | 3.81 |
| 298.37 | 3.01 | 3.01 |
| 352.34 | 3.72 | 3.72 |
| 317.77 | 3.94 | 3.94 |
| 309.35 | 2.57 | 2.57 |
| 315.76 | 3.58 | 3.58 |
| 165.22 | 1.60 | 1.60 |
| 278.33 | 0.92 | 0.92 |
| 322.18 | 3.48 | 3.48 |
| 339.27 | 3.66 | 3.66 |
| 269.73 | 3.56 | 3.56 |
| 272.26 | 2.04 | 2.04 |
| 315.71 | 4.04 | 4.04 |
| 335.74 | 3.31 | 3.31 |
| 257.31 | 3.06 | 3.06 |
| 245.28 | 3.19 | 3.19 |
| 279.24 | 2.93 | 2.93 |