ID: ALA1737963
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS for the identification of inhibitors of NALP3 in yeast using a luminescent assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2825, AID2832]
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA1737963
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
252.27 | 3.47 | 3.47 |
541.51 | 4.73 | 4.73 |
364.78 | 2.69 | 2.69 |
610.73 | 7.85 | 7.85 |
318.38 | 4.03 | 4.03 |
315.59 | 5.29 | 5.29 |
292.21 | 2.55 | 2.55 |
252.28 | 2.24 | 2.24 |
340.69 | 3.97 | 3.97 |
351.36 | 1.63 | 1.63 |
366.87 | 4.13 | 4.13 |
251.28 | 2.69 | 2.69 |
461.37 | 4.04 | 4.04 |
375.38 | 3.30 | 3.30 |
355.33 | 1.46 | 1.46 |
317.69 | 2.86 | 2.86 |
419.35 | 4.65 | 4.65 |
528.07 | 3.35 | 3.35 |
328.80 | 4.44 | 4.44 |
362.14 | 2.97 | 2.97 |
317.68 | 3.73 | 3.73 |
227.26 | 2.95 | 2.95 |
333.34 | 1.48 | 1.48 |
341.36 | 4.50 | 4.50 |
298.37 | 3.43 | 3.43 |
280.37 | 2.71 | 2.71 |
258.36 | 4.25 | 4.25 |
272.70 | 2.64 | 2.64 |
423.25 | 2.31 | 2.31 |
378.91 | 4.09 | 4.09 |
431.24 | 6.27 | 6.27 |
343.86 | 4.00 | 4.00 |
346.48 | 3.29 | 3.29 |
360.89 | 3.21 | 3.21 |
319.39 | 2.08 | 2.08 |
377.37 | 4.97 | 4.97 |
265.36 | 4.32 | 4.32 |
296.29 | 1.29 | 1.29 |
321.30 | 4.00 | 4.00 |
430.51 | 3.51 | 3.51 |
316.15 | 4.45 | 4.45 |
299.17 | 4.30 | 4.30 |
383.76 | 4.28 | 4.28 |
354.41 | 3.82 | 3.82 |
407.30 | 3.54 | 3.54 |
246.27 | 1.78 | 1.78 |
578.00 | 3.59 | 3.59 |
401.88 | 3.66 | 3.66 |
271.71 | 3.86 | 3.86 |
317.41 | 3.36 | 3.36 |
278.31 | 3.36 | 3.36 |
375.49 | 2.77 | 2.77 |
363.46 | 2.49 | 2.49 |
381.40 | 4.70 | 4.70 |
274.32 | 1.60 | 1.60 |
308.29 | 2.37 | 2.37 |
329.38 | 1.82 | 1.82 |
372.47 | 1.81 | 1.81 |
340.22 | 1.70 | 1.70 |
332.24 | 4.20 | 4.20 |
333.41 | 2.39 | 2.39 |
319.36 | 4.08 | 4.08 |
254.31 | 3.75 | 3.75 |
310.38 | 3.65 | 3.65 |
622.45 | 3.70 | 3.70 |
405.97 | 6.56 | 6.56 |
450.46 | 2.38 | 2.38 |
282.35 | 2.97 | 2.97 |
415.53 | 3.33 | 3.33 |