Basic Information
ID: ALA1737980
Type: Functional
Description: PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors: Validation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493163, AID504444, AID504648]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1737980
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 317.18 | 4.50 | 4.50 |
| 232.24 | 1.42 | 1.42 |
| 357.79 | 3.93 | 3.93 |
| 246.19 | -1.69 | -1.69 |
| 160.22 | 1.67 | 1.67 |
| 202.26 | 1.82 | 1.82 |
| 391.56 | 6.86 | 6.86 |
| 168.15 | 1.22 | 1.22 |
| 454.61 | 5.09 | 5.09 |
| 414.53 | 3.37 | 3.37 |
| 407.51 | 4.95 | 4.95 |
| 121.14 | 0.79 | 0.79 |
| 252.35 | 0.60 | 0.60 |
| 211.26 | 1.13 | 1.13 |
| 300.44 | 5.60 | 5.60 |
| 263.38 | 3.83 | 3.83 |
| 399.97 | 5.97 | 5.97 |
| 393.47 | 4.51 | 4.51 |
| 305.21 | 1.93 | 1.93 |
| 329.36 | 4.06 | 4.06 |
| 394.42 | 3.70 | 3.70 |
| 315.76 | 4.04 | 4.04 |
| 196.20 | 0.64 | 0.64 |
| 214.22 | 0.73 | 0.73 |
| 254.24 | 2.87 | 2.87 |
| 385.51 | 2.09 | 2.09 |
| 335.45 | 5.43 | 5.43 |
| 361.53 | 4.84 | 4.84 |
| 444.49 | -0.14 | -0.14 |
| 395.48 | 3.22 | 3.22 |
| 348.36 | 2.08 | 2.08 |
| 301.33 | 3.03 | 3.03 |
| 494.01 | 3.64 | 3.64 |
| 370.59 | 5.89 | 5.89 |
| 369.37 | 3.52 | 3.52 |
| 1202.63 | ||
| 376.50 | 4.72 | 4.72 |
| 204.23 | 0.83 | 0.83 |
| 473.59 | 6.08 | 6.08 |
| 654.61 | 3.19 | 3.19 |
| 853.92 | 3.74 | 3.74 |
| 440.42 | 0.24 | 0.24 |
| 160.18 | 0.92 | 0.92 |
| 319.45 | 3.94 | 3.94 |
| 414.41 | 2.41 | 2.41 |
| 125.17 | 0.30 | 0.30 |
| 296.15 | 4.74 | 4.74 |
| 304.22 | 3.38 | 3.38 |
| 332.34 | 3.43 | 3.43 |
| 348.38 | 3.72 | 3.72 |
| 348.49 | 6.29 | 6.29 |
| 562.67 | 7.50 | 7.50 |
| 314.47 | 4.72 | 4.72 |
| 238.29 | 3.12 | 3.12 |
| 344.85 | 5.38 | 5.38 |
| 211.66 | 1.17 | 1.17 |
| 394.86 | 5.13 | 5.13 |
| 399.44 | 2.87 | 2.87 |
| 283.26 | 3.06 | 3.06 |
| 270.33 | 3.01 | 3.01 |
| 242.27 | 2.75 | 2.75 |
| 325.54 | 5.13 | 5.13 |
| 285.69 | 2.77 | 2.77 |
| 331.35 | 4.65 | 4.65 |
| 360.35 | 4.85 | 4.85 |
| 204.30 | 2.15 | 2.15 |
| 371.40 | 0.36 | 0.36 |
| 339.39 | 3.86 | 3.86 |
| 403.53 | 4.06 | 4.06 |
| 170.24 | 0.58 | 0.58 |
| 246.31 | 4.49 | 4.49 |
| 230.31 | 3.30 | 3.30 |
| 450.57 | 5.32 | 5.32 |
| 502.77 | 7.28 | 7.28 |
| 341.45 | 3.24 | 3.24 |
| 294.44 | 4.12 | 4.12 |
| 151.25 | 1.91 | 1.91 |
| 1297.30 | ||
| 393.57 | 6.21 | 6.21 |
| 252.19 | 0.42 | 0.42 |
| 213.66 | 1.86 | 1.86 |
| 179.22 | 2.12 | 2.12 |
| 110.11 | 1.10 | 1.10 |
| 373.95 | 4.58 | 4.58 |
| 234.20 | 2.78 | 2.78 |
| 308.38 | 0.53 | 0.53 |
| 303.83 | 4.19 | 4.19 |
| 472.09 | 8.01 | 8.01 |
| 542.42 | 4.16 | 4.16 |
| 434.52 | 3.70 | 3.70 |
| 422.57 | 3.83 | 3.83 |
| 582.92 | 7.22 | 7.22 |
| 395.47 | 4.23 | 4.23 |
| 312.80 | 2.57 | 2.57 |
| 454.45 | 0.27 | 0.27 |
| 267.28 | 3.05 | 3.05 |
| 342.44 | 3.48 | 3.48 |
| 369.47 | 3.46 | 3.46 |
| 516.55 | 5.40 | 5.40 |
| 243.22 | -2.56 | -2.56 |
| 276.21 | 3.21 | 3.21 |
| 179.31 | 2.69 | 2.69 |
| 180.21 | 2.78 | 2.78 |
| 275.09 | 1.27 | 1.27 |
| 582.79 | 6.80 | 6.80 |
| 258.28 | 1.55 | 1.55 |
| 145.11 | -1.11 | -1.11 |
| 182.17 | -0.23 | -0.23 |
| 477.05 | 5.09 | 5.09 |
| 292.34 | 3.17 | 3.17 |
| 246.10 | 1.55 | 1.55 |
| 475.58 | 5.31 | 5.31 |
| 368.52 | 5.11 | 5.11 |
| 334.42 | 2.38 | 2.38 |
| 195.22 | 2.68 | 2.68 |
| 370.46 | 5.59 | 5.59 |
| 495.64 | 5.27 | 5.27 |
| 302.41 | 3.62 | 3.62 |
| 274.18 | ||
| 480.65 | 4.94 | 4.94 |
| 327.18 | 4.09 | 4.09 |
| 518.56 | 6.38 | 6.38 |
| 153.18 | 0.38 | 0.38 |
| 225.25 | 2.03 | 2.03 |
| 390.52 | 3.95 | 3.95 |
| 308.31 | 2.76 | 2.76 |
| 504.64 | -0.02 | -0.02 |
| 280.28 | 2.64 | 2.64 |
| 418.28 | 3.49 | 3.49 |
| 270.21 | 3.25 | 3.25 |
| 419.42 | 0.64 | 0.64 |
| 296.55 | 3.62 | 3.62 |
| 351.86 | 2.69 | 2.69 |
| 331.80 | 3.33 | 3.33 |
| 282.22 | 3.54 | 3.54 |
| 182.08 | ||
| 312.41 | 2.53 | 2.53 |
| 193.25 | 2.79 | 2.79 |
| 256.26 | 0.63 | 0.63 |
| 463.34 | 3.94 | 3.94 |
| 436.62 | 7.51 | 7.51 |
| 448.44 | 1.65 | 1.65 |
| 228.25 | 2.97 | 2.97 |
| 244.25 | 2.68 | 2.68 |
| 382.89 | 4.89 | 4.89 |
| 469.67 | 7.22 | 7.22 |
| 520.95 | 5.01 | 5.01 |
| 447.36 | 4.83 | 4.83 |
| 333.47 | 3.40 | 3.40 |
| 385.51 | 1.20 | 1.20 |
| 282.39 | 4.42 | 4.42 |
| 218.30 | 1.76 | 1.76 |
| 287.32 | 3.10 | 3.10 |
| 330.47 | 3.84 | 3.84 |
| 268.74 | 1.40 | 1.40 |
| 293.32 | 4.03 | 4.03 |
| 264.33 | 3.25 | 3.25 |
| 195.26 | 3.56 | 3.56 |
| 213.24 | 3.51 | 3.51 |
| 302.37 | 3.57 | 3.57 |
| 136.20 | 0.69 | 0.69 |
| 650.76 | 3.93 | 3.93 |
| 286.36 | 3.59 | 3.59 |
| 313.79 | 3.43 | 3.43 |
| 307.35 | 3.30 | 3.30 |
| 291.38 | 1.22 | 1.22 |
| 380.50 | 3.12 | 3.12 |
| 399.56 | 5.72 | 5.72 |
| 327.34 | 3.05 | 3.05 |
| 523.74 | 6.49 | 6.49 |
| 346.47 | 2.67 | 2.67 |
| 335.67 | 3.04 | 3.04 |
| 499.53 | -0.16 | -0.16 |
| 456.68 | 6.17 | 6.17 |
| 510.29 | 0.41 | 0.41 |
| 375.47 | 4.20 | 4.20 |
| 212.21 | 1.31 | 1.31 |
| 277.28 | 4.42 | 4.42 |
| 363.80 | 5.76 | 5.76 |
| 425.23 | -0.26 | -0.26 |
| 354.46 | 3.20 | 3.20 |
| 272.70 | 0.80 | 0.80 |
| 385.42 | 0.48 | 0.48 |
| 265.34 | 0.73 | 0.73 |
| 317.22 | 2.45 | 2.45 |
| 402.44 | 3.86 | 3.86 |
| 531.44 | 4.21 | 4.21 |
| 244.29 | 2.29 | 2.29 |
| 200.11 | 0.91 | 0.91 |
| 356.18 | 5.18 | 5.18 |
| 573.64 | ||
| 434.71 | 4.01 | 4.01 |
| 376.20 | 4.80 | 4.80 |
| 406.50 | 3.21 | 3.21 |
| 606.78 | 8.68 | 8.68 |
| 367.37 | 4.23 | 4.23 |
| 596.43 | 6.73 | 6.73 |
| 244.24 | 3.42 | 3.42 |
| 332.48 | 3.77 | 3.77 |
| 413.43 | 2.88 | 2.88 |
| 357.41 | -1.25 | -1.25 |
| 279.10 | -0.20 | -0.20 |
| 337.42 | 4.41 | 4.41 |
| 310.44 | 5.95 | 5.95 |
| 270.37 | 3.82 | 3.82 |
| 395.42 | 2.53 | 2.53 |
| 305.29 | 3.12 | 3.12 |
| 319.76 | 0.54 | 0.54 |
| 461.56 | 5.86 | 5.86 |
| 478.55 | 5.18 | 5.18 |
| 130.08 | -0.80 | -0.80 |
| 444.44 | -0.35 | -0.35 |
| 584.66 | -1.51 | -1.51 |
| 433.72 | 4.61 | 4.61 |
| 476.79 | 4.68 | 4.68 |
| 451.68 | 5.28 | 5.28 |
| 362.47 | 1.78 | 1.78 |
| 360.01 | 3.51 | 3.51 |
| 327.12 | 3.86 | 3.86 |
| 396.83 | 3.76 | 3.76 |
| 434.28 | 6.35 | 6.35 |
| 394.44 | 0.62 | 0.62 |
| 481.68 | 6.23 | 6.23 |
| 479.53 | 3.68 | 3.68 |
| 198.18 | -1.03 | -1.03 |
| 310.40 | 1.73 | 1.73 |
| 417.63 | 6.79 | 6.79 |
| 244.21 | -3.17 | -3.17 |
| 304.32 | 2.98 | 2.98 |
| 611.74 | 6.48 | 6.48 |
| 346.47 | 2.81 | 2.81 |
| 346.34 | 2.18 | 2.18 |
| 430.55 | 2.77 | 2.77 |
| 343.34 | 0.18 | 0.18 |
| 241.25 | 1.91 | 1.91 |
| 249.34 | 3.06 | 3.06 |
| 308.34 | 2.88 | 2.88 |
| 218.21 | 1.57 | 1.57 |
| 343.43 | 4.69 | 4.69 |
| 241.25 | -1.70 | -1.70 |
| 207.25 | 1.81 | 1.81 |
| 119.08 | -0.26 | -0.26 |
| 492.53 | 4.28 | 4.28 |
| 360.44 | 4.55 | 4.55 |
| 248.32 | 2.76 | 2.76 |
| 308.30 | -1.84 | -1.84 |
| 179.14 | -1.41 | -1.41 |
| 264.13 | 2.99 | 2.99 |
| 244.21 | -3.01 | -3.01 |
| 264.22 | 0.41 | 0.41 |
| 311.34 | 3.21 | 3.21 |
| 320.05 | 5.93 | 5.93 |
| 384.31 | 1.45 | 1.45 |
| 316.47 | 4.18 | 4.18 |
| 544.74 | 1.06 | 1.06 |
| 496.68 | 3.80 | 3.80 |
| 490.65 | 3.87 | 3.87 |
| 257.27 | 1.95 | 1.95 |
| 361.53 | 5.53 | 5.53 |
| 193.16 | 1.66 | 1.66 |
| 371.46 | 2.64 | 2.64 |
| 452.56 | 3.91 | 3.91 |
| 402.44 | 1.90 | 1.90 |
| 603.76 | 4.11 | 4.11 |
| 774.17 | 3.85 | 3.85 |
| 836.39 | -2.45 | -2.45 |
| 267.36 | 3.13 | 3.13 |
| 319.25 | 3.93 | 3.93 |
| 246.22 | 1.93 | 1.93 |
| 652.26 | 10.29 | 10.29 |
| 244.23 | 1.82 | 1.82 |
| 181.22 | 0.28 | 0.28 |
| 231.08 | 2.66 | 2.66 |
| 286.40 | 3.70 | 3.70 |
| 555.66 | 4.26 | 4.26 |
| 277.21 | 2.38 | 2.38 |
| 185.23 | 2.15 | 2.15 |
| 330.41 | 2.22 | 2.22 |
| 523.63 | 5.53 | 5.53 |
| 300.31 | 3.34 | 3.34 |
| 334.50 | 3.57 | 3.57 |
| 466.48 | 0.42 | 0.42 |
| 343.81 | 4.29 | 4.29 |
| 296.43 | 4.33 | 4.33 |
| 323.35 | 3.27 | 3.27 |
| 339.44 | 3.25 | 3.25 |
| 321.16 | 4.09 | 4.09 |
| 429.60 | 5.41 | 5.41 |
| 277.35 | 0.83 | 0.83 |
| 404.43 | 2.96 | 2.96 |
| 366.46 | 4.15 | 4.15 |
| 402.51 | 3.85 | 3.85 |
| 276.61 | 3.51 | 3.51 |
| 211.20 | 1.35 | 1.35 |
| 327.43 | 5.74 | 5.74 |
| 491.65 | 5.96 | 5.96 |
| 198.23 | 1.87 | 1.87 |
| 171.29 | 0.19 | 0.19 |
| 287.75 | 4.00 | 4.00 |
| 213.67 | 4.04 | 4.04 |
| 438.58 | 5.32 | 5.32 |
| 268.23 | 0.97 | 0.97 |
| 392.55 | 5.74 | 5.74 |
| 456.50 | 1.53 | 1.53 |
| 824.97 | 3.52 | 3.52 |
| 394.49 | 4.04 | 4.04 |
| 220.28 | 3.48 | 3.48 |
| 225.20 | -1.63 | -1.63 |
| 810.99 | 3.99 | 3.99 |
| 319.14 | 1.02 | 1.02 |
| 588.56 | 1.69 | 1.69 |
| 264.28 | 1.67 | 1.67 |
| 268.32 | 2.72 | 2.72 |
| 415.49 | 3.84 | 3.84 |
| 586.68 | -1.44 | -1.44 |
| 408.92 | 2.17 | 2.17 |
| 390.57 | 3.68 | 3.68 |
| 419.35 | 3.74 | 3.74 |
| 331.35 | 1.80 | 1.80 |
| 343.20 | 1.52 | 1.52 |
| 337.46 | 4.22 | 4.22 |
| 508.45 | 5.68 | 5.68 |
| 293.35 | 0.26 | 0.26 |
| 280.36 | 2.11 | 2.11 |
| 249.36 | 2.74 | 2.74 |
| 332.53 | 4.99 | 4.99 |
| 310.46 | 5.07 | 5.07 |
| 375.17 | -0.39 | -0.39 |
| 448.55 | 0.94 | 0.94 |
| 222.31 | 0.64 | 0.64 |
| 392.47 | 1.90 | 1.90 |
| 257.38 | 3.04 | 3.04 |
| 222.31 | 0.64 | 0.64 |
| 220.23 | 4.43 | 4.43 |
| 314.21 | 3.78 | 3.78 |
| 392.50 | 2.39 | 2.39 |
| 875.11 | 5.60 | 5.60 |
| 427.67 | 5.01 | 5.01 |