Basic Information
ID: ALA1737990
Type: Functional
Description: PUBCHEM_BIOASSAY: qHTS for Small Molecule Agonists and Allosteric Enhancers of Human TRH Receptor: Confirmation Screen for Agonists. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485365, AID493056]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1737990
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 365.39 | 2.71 | 2.71 |
| 280.37 | 3.58 | 3.58 |
| 229.30 | 3.23 | 3.23 |
| 338.28 | 4.62 | 4.62 |
| 363.49 | 4.88 | 4.88 |
| 380.44 | 4.55 | 4.55 |
| 367.41 | 3.21 | 3.21 |
| 308.17 | 4.05 | 4.05 |
| 371.39 | 4.25 | 4.25 |
| 365.48 | 3.17 | 3.17 |
| 398.42 | 2.54 | 2.54 |
| 222.25 | 2.97 | 2.97 |
| 372.50 | 4.62 | 4.62 |
| 354.29 | 5.20 | 5.20 |
| 331.38 | 3.29 | 3.29 |
| 371.37 | 3.39 | 3.39 |
| 316.43 | 1.34 | 1.34 |
| 217.29 | 0.84 | 0.84 |
| 364.45 | 3.83 | 3.83 |
| 376.24 | 3.47 | 3.47 |
| 457.50 | 3.96 | 3.96 |
| 518.57 | 3.00 | 3.00 |
| 454.62 | 5.24 | 5.24 |
| 394.48 | 4.58 | 4.58 |
| 366.45 | 2.85 | 2.85 |
| 327.34 | 3.60 | 3.60 |
| 394.23 | 3.31 | 3.31 |
| 425.28 | 3.35 | 3.35 |
| 476.56 | 3.99 | 3.99 |
| 241.29 | 2.49 | 2.49 |
| 372.47 | 4.06 | 4.06 |
| 311.30 | 1.65 | 1.65 |
| 316.37 | 1.44 | 1.44 |
| 359.45 | 4.54 | 4.54 |
| 362.38 | 5.16 | 5.16 |
| 442.97 | 6.58 | 6.58 |
| 473.36 | 3.79 | 3.79 |
| 239.32 | 3.42 | 3.42 |
| 418.84 | 3.20 | 3.20 |
| 296.37 | 4.03 | 4.03 |
| 373.36 | 3.93 | 3.93 |
| 358.78 | 2.56 | 2.56 |
| 211.27 | 2.64 | 2.64 |
| 424.83 | 5.81 | 5.81 |
| 332.36 | 2.44 | 2.44 |
| 360.41 | 3.38 | 3.38 |
| 352.39 | 2.68 | 2.68 |
| 354.22 | 3.87 | 3.87 |
| 360.44 | 2.91 | 2.91 |
| 313.38 | 4.19 | 4.19 |
| 390.46 | 4.79 | 4.79 |
| 378.47 | 3.45 | 3.45 |
| 316.41 | 4.84 | 4.84 |
| 251.33 | 3.60 | 3.60 |
| 436.54 | 2.80 | 2.80 |
| 380.43 | 3.46 | 3.46 |
| 663.43 | -3.65 | -3.65 |
| 326.35 | 2.63 | 2.63 |
| 349.41 | 3.93 | 3.93 |
| 313.36 | 2.42 | 2.42 |
| 281.27 | 2.62 | 2.62 |
| 461.87 | 4.70 | 4.70 |
| 364.38 | 1.42 | 1.42 |
| 372.43 | 2.64 | 2.64 |
| 293.37 | 3.42 | 3.42 |
| 382.44 | 3.63 | 3.63 |
| 329.40 | 2.47 | 2.47 |
| 418.07 | 6.61 | 6.61 |
| 440.92 | 3.67 | 3.67 |
| 376.41 | 3.08 | 3.08 |
| 428.34 | 6.45 | 6.45 |
| 314.41 | 3.86 | 3.86 |
| 367.40 | 4.14 | 4.14 |
| 376.41 | 3.08 | 3.08 |
| 402.43 | 4.67 | 4.67 |
| 400.41 | 3.19 | 3.19 |
| 254.25 | 2.72 | 2.72 |
| 236.25 | 2.67 | 2.67 |
| 464.89 | 4.63 | 4.63 |
| 321.42 | 2.77 | 2.77 |
| 441.49 | 5.04 | 5.04 |
| 340.38 | 2.94 | 2.94 |
| 395.42 | 3.30 | 3.30 |
| 351.41 | 2.38 | 2.38 |
| 336.30 | 3.11 | 3.11 |
| 335.36 | 3.36 | 3.36 |
| 446.43 | 4.27 | 4.27 |
| 410.47 | 2.97 | 2.97 |
| 340.34 | 1.99 | 1.99 |
| 314.39 | 3.19 | 3.19 |
| 403.23 | 3.80 | 3.80 |
| 324.52 | 3.78 | 3.78 |
| 425.59 | 3.16 | 3.16 |
| 264.21 | 3.51 | 3.51 |
| 331.44 | 1.99 | 1.99 |
| 241.34 | 2.65 | 2.65 |
| 409.44 | 3.34 | 3.34 |
| 422.38 | 4.96 | 4.96 |
| 284.24 | 2.59 | 2.59 |
| 393.83 | 4.93 | 4.93 |
| 405.45 | 4.27 | 4.27 |
| 333.35 | 4.54 | 4.54 |
| 497.50 | 5.51 | 5.51 |
| 413.46 | 1.23 | 1.23 |
| 302.80 | 2.64 | 2.64 |
| 442.01 | 6.41 | 6.41 |
| 474.58 | 4.29 | 4.29 |
| 415.49 | 3.30 | 3.30 |
| 316.33 | 2.64 | 2.64 |
| 372.47 | 3.65 | 3.65 |
| 290.32 | 3.64 | 3.64 |
| 299.72 | 2.66 | 2.66 |
| 448.30 | 3.12 | 3.12 |
| 394.54 | 4.45 | 4.45 |
| 422.47 | 1.72 | 1.72 |
| 355.19 | 3.81 | 3.81 |
| 321.38 | 3.63 | 3.63 |
| 286.38 | 4.02 | 4.02 |
| 406.51 | 3.89 | 3.89 |
| 347.37 | 3.13 | 3.13 |
| 308.34 | 3.52 | 3.52 |
| 535.64 | 4.67 | 4.67 |
| 226.24 | 2.63 | 2.63 |
| 350.33 | 1.46 | 1.46 |
| 428.45 | 2.55 | 2.55 |
| 306.29 | 3.52 | 3.52 |
| 404.45 | 3.64 | 3.64 |
| 348.41 | 5.13 | 5.13 |
| 348.35 | 3.09 | 3.09 |
| 349.35 | 4.80 | 4.80 |
| 291.35 | 3.57 | 3.57 |
| 335.41 | 4.47 | 4.47 |
| 332.19 | 5.12 | 5.12 |
| 354.36 | 2.38 | 2.38 |
| 387.69 | 3.27 | 3.27 |
| 348.42 | 2.97 | 2.97 |
| 339.33 | 2.28 | 2.28 |
| 352.39 | 3.19 | 3.19 |
| 264.28 | 2.76 | 2.76 |
| 406.41 | 2.67 | 2.67 |
| 254.29 | 2.13 | 2.13 |
| 404.30 | 4.22 | 4.22 |
| 246.33 | 3.21 | 3.21 |
| 492.99 | 4.92 | 4.92 |
| 295.32 | 3.05 | 3.05 |
| 294.25 | 3.44 | 3.44 |
| 358.45 | 3.03 | 3.03 |
| 417.65 | 3.95 | 3.95 |
| 494.50 | 3.12 | 3.12 |
| 462.89 | 2.44 | 2.44 |
| 275.38 | 2.46 | 2.46 |
| 339.46 | 4.60 | 4.60 |
| 441.51 | 2.81 | 2.81 |
| 381.43 | 1.67 | 1.67 |
| 435.50 | 4.87 | 4.87 |
| 291.31 | 3.34 | 3.34 |
| 316.43 | 1.34 | 1.34 |
| 275.26 | 2.98 | 2.98 |
| 385.49 | 5.91 | 5.91 |
| 450.58 | 2.86 | 2.86 |
| 364.35 | 4.08 | 4.08 |
| 374.23 | 3.90 | 3.90 |
| 465.08 | 4.68 | 4.68 |
| 457.91 | 3.07 | 3.07 |
| 358.44 | 3.63 | 3.63 |
| 437.92 | 4.33 | 4.33 |
| 432.48 | 2.66 | 2.66 |
| 221.26 | 3.34 | 3.34 |
| 419.83 | 2.59 | 2.59 |
| 452.00 | 3.89 | 3.89 |
| 362.39 | -1.81 | -1.81 |
| 359.39 | 3.51 | 3.51 |
| 460.56 | 2.02 | 2.02 |
| 489.62 | 3.41 | 3.41 |
| 359.18 | 3.66 | 3.66 |
| 294.31 | 3.91 | 3.91 |
| 380.41 | 4.32 | 4.32 |
| 348.38 | 2.30 | 2.30 |
| 388.40 | 3.42 | 3.42 |
| 437.52 | 3.48 | 3.48 |
| 405.48 | 2.28 | 2.28 |
| 254.31 | 3.75 | 3.75 |
| 278.31 | 3.76 | 3.76 |
| 441.44 | 5.23 | 5.23 |
| 296.35 | 3.37 | 3.37 |
| 365.46 | 3.01 | 3.01 |
| 310.14 | 2.86 | 2.86 |
| 396.47 | 0.29 | 0.29 |
| 338.50 | 3.03 | 3.03 |
| 321.34 | 2.20 | 2.20 |
| 485.43 | 2.28 | 2.28 |
| 283.35 | 4.45 | 4.45 |
| 321.36 | 4.41 | 4.41 |
| 417.42 | 3.51 | 3.51 |
| 403.24 | 2.88 | 2.88 |
| 389.46 | 3.25 | 3.25 |
| 448.50 | 2.56 | 2.56 |