Basic Information
ID: ALA1738019
Type: Unassigned
Description: PUBCHEM_BIOASSAY: Late stage results from the probe development effort to identify inhibitors of the Janus kinase 2 mutant JAK2V617F. (Class of assay: screening) [Related pubchem assays (depositor defined):AID1446, AID1486, AID1520, AID1521, AID1691, AID1699, AID1797] Panel member name: irf1 Inhibition (HEL cells)
Cell type: HEL
Activity Charts
Bioactivity
Activity Types for Assay ALA1738019
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 315.76 | 4.04 | 4.04 |
| 393.44 | 3.41 | 3.41 |
| 253.27 | 0.83 | 0.83 |
| 360.21 | 4.15 | 4.15 |
| 388.26 | 4.93 | 4.93 |
| 336.39 | 3.14 | 3.14 |
| 308.34 | 2.36 | 2.36 |
| 322.36 | 2.75 | 2.75 |
| 295.34 | 3.70 | 3.70 |
| 266.30 | 3.31 | 3.31 |
| 266.30 | 3.32 | 3.32 |
| 186.17 | 1.53 | 1.53 |
| 388.90 | 4.23 | 4.23 |
| 281.31 | 3.39 | 3.39 |
| 397.48 | 3.70 | 3.70 |
| 240.44 | 2.06 | 2.06 |
| 311.34 | 3.40 | 3.40 |
| 245.19 | -3.46 | -3.46 |
| 358.38 | 2.06 | 2.06 |
| 376.21 | 3.86 | 3.86 |
| 292.17 | 4.03 | 4.03 |
| 282.30 | 3.10 | 3.10 |
| 200.24 | 2.57 | 2.57 |
| 174.09 | -1.10 | -1.10 |
| 206.25 | 2.39 | 2.39 |
| 442.52 | 5.28 | 5.28 |
| 442.97 | 4.43 | 4.43 |
| 270.76 | 2.02 | 2.02 |
| 473.23 | 4.43 | 4.43 |
| 373.66 | 3.25 | 3.25 |
| 289.67 | 3.49 | 3.49 |
| 293.37 | 2.71 | 2.71 |
| 356.81 | 4.21 | 4.21 |
| 334.33 | 0.08 | 0.08 |
| 327.81 | 2.60 | 2.60 |
| 519.58 | 4.06 | 4.06 |
| 330.39 | 4.06 | 4.06 |
| 229.24 | 1.49 | 1.49 |
| 423.54 | 3.96 | 3.96 |
| 259.28 | 3.15 | 3.15 |
| 246.22 | 2.75 | 2.75 |
| 249.71 | 2.24 | 2.24 |
| 423.54 | 3.96 | 3.96 |
| 336.19 | 3.81 | 3.81 |
| 346.34 | 2.19 | 2.19 |
| 253.77 | 3.84 | 3.84 |
| 353.46 | 3.77 | 3.77 |
| 278.23 | 3.82 | 3.82 |
| 355.44 | 4.20 | 4.20 |
| 273.76 | 3.77 | 3.77 |
| 368.39 | 3.18 | 3.18 |
| 329.21 | 3.14 | 3.14 |
| 346.65 | 4.03 | 4.03 |
| 389.46 | 3.57 | 3.57 |
| 343.81 | 3.74 | 3.74 |
| 285.74 | 3.09 | 3.09 |
| 280.33 | 3.77 | 3.77 |
| 249.29 | 1.86 | 1.86 |
| 319.67 | 2.09 | 2.09 |
| 323.40 | 2.72 | 2.72 |
| 374.19 | 3.90 | 3.90 |
| 328.73 | 2.48 | 2.48 |
| 301.78 | 1.72 | 1.72 |
| 355.44 | 1.48 | 1.48 |
| 292.24 | 2.16 | 2.16 |
| 263.73 | 2.55 | 2.55 |
| 457.55 | 4.16 | 4.16 |
| 312.38 | 1.57 | 1.57 |
| 339.44 | 3.23 | 3.23 |
| 395.46 | 3.49 | 3.49 |
| 257.29 | 2.72 | 2.72 |
| 279.73 | 2.33 | 2.33 |
| 352.32 | 0.22 | 0.22 |
| 426.49 | 2.90 | 2.90 |
| 457.55 | 4.16 | 4.16 |
| 388.25 | 3.92 | 3.92 |
| 285.13 | 2.85 | 2.85 |
| 401.96 | 4.95 | 4.95 |
| 262.70 | 2.68 | 2.68 |
| 311.78 | 3.66 | 3.66 |
| 279.72 | 3.79 | 3.79 |
| 275.31 | 2.99 | 2.99 |
| 398.39 | 2.01 | 2.01 |
| 246.74 | 1.88 | 1.88 |
| 296.28 | 2.30 | 2.30 |
| 293.33 | 4.50 | 4.50 |
| 288.31 | 3.02 | 3.02 |
| 305.77 | 3.63 | 3.63 |
| 240.65 | -0.01 | -0.01 |
| 401.48 | 3.56 | 3.56 |
| 326.40 | 4.35 | 4.35 |
| 365.01 | 4.22 | 4.22 |
| 265.70 | 1.94 | 1.94 |
| 264.80 | 3.54 | 3.54 |
| 380.44 | 4.27 | 4.27 |
| 323.39 | 3.88 | 3.88 |
| 291.78 | 3.35 | 3.35 |
| 382.41 | 4.01 | 4.01 |
| 338.46 | 5.31 | 5.31 |
| 466.54 | 4.35 | 4.35 |
| 345.49 | 4.54 | 4.54 |
| 333.56 | 3.02 | 3.02 |
| 461.52 | 3.99 | 3.99 |
| 346.83 | 3.47 | 3.47 |
| 324.43 | 1.96 | 1.96 |
| 334.33 | 3.37 | 3.37 |
| 358.47 | 3.70 | 3.70 |
| 401.96 | 4.95 | 4.95 |
| 289.33 | 4.14 | 4.14 |
| 317.10 | 2.50 | 2.50 |
| 323.37 | 2.60 | 2.60 |
| 344.42 | 3.33 | 3.33 |
| 334.32 | 1.93 | 1.93 |
| 375.90 | 3.38 | 3.38 |
| 310.26 | 2.16 | 2.16 |
| 264.28 | 3.76 | 3.76 |
| 305.83 | 4.63 | 4.63 |
| 250.37 | 2.47 | 2.47 |
| 311.36 | 4.01 | 4.01 |
| 357.35 | 3.75 | 3.75 |
| 293.37 | 3.87 | 3.87 |
| 271.32 | 3.03 | 3.03 |
| 317.30 | 3.67 | 3.67 |
| 247.30 | 2.47 | 2.47 |
| 287.36 | 3.39 | 3.39 |
| 257.72 | 3.37 | 3.37 |
| 397.48 | 3.99 | 3.99 |
| 485.54 | 4.53 | 4.53 |
| 312.07 | 2.13 | 2.13 |
| 545.64 | 6.49 | 6.49 |
| 327.81 | 4.11 | 4.11 |
| 372.26 | 4.22 | 4.22 |
| 340.40 | 3.09 | 3.09 |
| 271.29 | 3.03 | 3.03 |
| 285.32 | 3.83 | 3.83 |
| 310.38 | 3.12 | 3.12 |
| 335.45 | 4.58 | 4.58 |
| 369.40 | 5.23 | 5.23 |
| 261.32 | 2.86 | 2.86 |
| 294.31 | 0.97 | 0.97 |
| 332.81 | 4.45 | 4.45 |
| 309.37 | 3.82 | 3.82 |
| 307.39 | 3.77 | 3.77 |
| 365.31 | 4.29 | 4.29 |
| 419.26 | 4.06 | 4.06 |
| 362.26 | 4.77 | 4.77 |
| 312.39 | 4.11 | 4.11 |
| 245.28 | 2.24 | 2.24 |
| 372.26 | 4.22 | 4.22 |
| 323.39 | 3.47 | 3.47 |
| 369.44 | 2.36 | 2.36 |
| 390.53 | 5.29 | 5.29 |
| 327.81 | 4.11 | 4.11 |
| 265.27 | 3.26 | 3.26 |
| 316.81 | 3.42 | 3.42 |
| 362.81 | 2.99 | 2.99 |
| 280.78 | 2.57 | 2.57 |
| 322.22 | 5.66 | 5.66 |
| 335.64 | 3.57 | 3.57 |
| 301.20 | 2.92 | 2.92 |
| 344.37 | 3.80 | 3.80 |
| 409.31 | 3.72 | 3.72 |
| 385.47 | 3.82 | 3.82 |
| 479.49 | 2.59 | 2.59 |
| 323.35 | 2.64 | 2.64 |