Basic Information
ID: ALA1738027
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493011, AID493024]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1738027
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 318.20 | 1.58 | 1.58 |
| 279.39 | 3.75 | 3.75 |
| 497.37 | 3.62 | 3.62 |
| 227.26 | 3.02 | 3.02 |
| 575.63 | -1.40 | -1.40 |
| 390.45 | 4.19 | 4.19 |
| 352.44 | 3.71 | 3.71 |
| 380.27 | 3.06 | 3.06 |
| 422.35 | 4.26 | 4.26 |
| 375.25 | 3.56 | 3.56 |
| 495.79 | 4.65 | 4.65 |
| 394.30 | 3.54 | 3.54 |
| 439.42 | 4.69 | 4.69 |
| 412.30 | 2.41 | 2.41 |
| 368.24 | 3.27 | 3.27 |
| 320.22 | 2.94 | 2.94 |
| 451.39 | 5.11 | 5.11 |
| 402.23 | 2.28 | 2.28 |
| 373.41 | 1.15 | 1.15 |
| 420.40 | 4.19 | 4.19 |
| 363.24 | 0.45 | 0.45 |
| 523.06 | 2.78 | 2.78 |
| 438.58 | 4.68 | 4.68 |
| 358.35 | 3.59 | 3.59 |
| 310.40 | 2.14 | 2.14 |
| 386.51 | 3.27 | 3.27 |
| 249.29 | 2.80 | 2.80 |
| 352.49 | 2.81 | 2.81 |
| 349.48 | 3.27 | 3.27 |
| 456.37 | 2.76 | 2.76 |
| 364.25 | 2.10 | 2.10 |
| 389.52 | 2.06 | 2.06 |
| 415.84 | 2.78 | 2.78 |
| 463.58 | 3.92 | 3.92 |
| 376.46 | 2.96 | 2.96 |
| 435.57 | 3.67 | 3.67 |
| 381.40 | 3.66 | 3.66 |
| 442.90 | 3.72 | 3.72 |
| 477.54 | 3.21 | 3.21 |
| 506.60 | 2.00 | 2.00 |
| 376.24 | 3.47 | 3.47 |
| 418.54 | 3.91 | 3.91 |
| 429.46 | 4.28 | 4.28 |
| 417.33 | 3.10 | 3.10 |
| 452.34 | 2.61 | 2.61 |
| 388.68 | 2.79 | 2.79 |
| 337.34 | 1.88 | 1.88 |
| 335.39 | 3.64 | 3.64 |
| 394.43 | 2.81 | 2.81 |
| 502.35 | 3.71 | 3.71 |
| 430.92 | 2.88 | 2.88 |
| 206.18 | -0.87 | -0.87 |
| 303.45 | 4.02 | 4.02 |
| 348.18 | 0.42 | 0.42 |
| 429.30 | 3.03 | 3.03 |
| 440.55 | 4.27 | 4.27 |
| 258.41 | 2.27 | 2.27 |
| 403.53 | 4.55 | 4.55 |
| 363.33 | 3.86 | 3.86 |
| 337.45 | 2.16 | 2.16 |
| 459.62 | 2.91 | 2.91 |
| 384.41 | 2.80 | 2.80 |
| 475.51 | 4.43 | 4.43 |
| 178.19 | 2.17 | 2.17 |
| 334.33 | 1.35 | 1.35 |
| 448.84 | 5.74 | 5.74 |
| 386.50 | 2.84 | 2.84 |
| 300.75 | 3.08 | 3.08 |
| 403.30 | 2.79 | 2.79 |
| 444.36 | 2.74 | 2.74 |
| 516.38 | 4.02 | 4.02 |
| 402.36 | 3.81 | 3.81 |
| 392.24 | 0.72 | 0.72 |
| 476.36 | 2.02 | 2.02 |
| 386.44 | 0.84 | 0.84 |
| 620.53 | 4.43 | 4.43 |
| 415.42 | 3.55 | 3.55 |
| 449.29 | 1.70 | 1.70 |
| 249.34 | 3.06 | 3.06 |
| 319.41 | 3.71 | 3.71 |
| 379.83 | 2.06 | 2.06 |
| 370.19 | 1.77 | 1.77 |
| 500.64 | 3.79 | 3.79 |
| 396.34 | 2.28 | 2.28 |
| 432.91 | 1.87 | 1.87 |
| 398.46 | 2.54 | 2.54 |
| 473.36 | 3.79 | 3.79 |
| 445.34 | 2.11 | 2.11 |
| 505.07 | 5.26 | 5.26 |
| 465.42 | 3.76 | 3.76 |
| 403.30 | 2.75 | 2.75 |
| 359.45 | 2.42 | 2.42 |
| 356.33 | 3.45 | 3.45 |
| 402.28 | 4.49 | 4.49 |
| 260.09 | 1.57 | 1.57 |
| 343.43 | 2.27 | 2.27 |
| 283.33 | 3.37 | 3.37 |
| 407.51 | 3.41 | 3.41 |
| 327.17 | 1.08 | 1.08 |
| 310.81 | 2.40 | 2.40 |
| 488.72 | 4.02 | 4.02 |
| 352.44 | 1.78 | 1.78 |
| 285.12 | 0.58 | 0.58 |
| 331.76 | 2.41 | 2.41 |
| 401.42 | 3.58 | 3.58 |
| 536.80 | 4.36 | 4.36 |
| 311.12 | -0.29 | -0.29 |
| 391.47 | 2.41 | 2.41 |
| 381.43 | 3.59 | 3.59 |
| 354.83 | 3.45 | 3.45 |
| 375.18 | 2.15 | 2.15 |
| 246.27 | 0.62 | 0.62 |
| 443.37 | 2.12 | 2.12 |
| 398.27 | 1.47 | 1.47 |
| 264.30 | 3.00 | 3.00 |
| 551.79 | 3.53 | 3.53 |
| 405.55 | 2.52 | 2.52 |
| 404.30 | 4.21 | 4.21 |
| 402.48 | 4.18 | 4.18 |
| 307.35 | 4.20 | 4.20 |
| 304.17 | 1.65 | 1.65 |
| 459.37 | 2.91 | 2.91 |
| 426.56 | 4.02 | 4.02 |
| 529.59 | 4.87 | 4.87 |
| 414.49 | 5.11 | 5.11 |
| 515.55 | 0.18 | 0.18 |
| 391.51 | 4.29 | 4.29 |
| 385.34 | 2.27 | 2.27 |
| 264.31 | 2.26 | 2.26 |
| 466.49 | 5.79 | 5.79 |
| 314.13 | 0.61 | 0.61 |
| 403.50 | 1.56 | 1.56 |
| 391.28 | 5.56 | 5.56 |
| 232.20 | 0.11 | 0.11 |
| 326.40 | 3.28 | 3.28 |
| 493.05 | 4.23 | 4.23 |
| 335.23 | 1.41 | 1.41 |
| 362.64 | 2.36 | 2.36 |
| 524.61 | 4.27 | 4.27 |
| 519.44 | 5.04 | 5.04 |
| 323.31 | 1.82 | 1.82 |
| 361.49 | 3.33 | 3.33 |
| 313.26 | 3.17 | 3.17 |
| 361.49 | 2.09 | 2.09 |
| 336.44 | 2.73 | 2.73 |
| 257.33 | 3.49 | 3.49 |
| 373.28 | 3.85 | 3.85 |
| 315.42 | 3.37 | 3.37 |
| 268.27 | 2.81 | 2.81 |
| 405.39 | 3.41 | 3.41 |
| 532.38 | 3.72 | 3.72 |
| 357.62 | 3.33 | 3.33 |
| 473.62 | 3.36 | 3.36 |
| 284.79 | 3.65 | 3.65 |
| 298.37 | 2.65 | 2.65 |
| 496.35 | 3.41 | 3.41 |
| 427.57 | 2.29 | 2.29 |
| 527.62 | 6.02 | 6.02 |
| 361.27 | 2.74 | 2.74 |
| 443.11 | 3.03 | 3.03 |
| 352.46 | 3.53 | 3.53 |
| 451.92 | 4.88 | 4.88 |
| 353.46 | 3.94 | 3.94 |
| 434.28 | 2.81 | 2.81 |
| 326.38 | 3.38 | 3.38 |
| 330.37 | 2.84 | 2.84 |
| 264.21 | 1.39 | 1.39 |
| 472.38 | 4.05 | 4.05 |
| 263.29 | 1.85 | 1.85 |
| 393.49 | 3.66 | 3.66 |
| 458.57 | 2.34 | 2.34 |
| 479.58 | 4.07 | 4.07 |
| 458.54 | 4.41 | 4.41 |
| 363.37 | 1.65 | 1.65 |
| 343.25 | 3.76 | 3.76 |
| 610.46 | 6.76 | 6.76 |
| 259.30 | 1.83 | 1.83 |
| 281.31 | 4.61 | 4.61 |
| 423.38 | 3.77 | 3.77 |
| 357.79 | 2.28 | 2.28 |
| 530.69 | 3.42 | 3.42 |
| 301.33 | 3.06 | 3.06 |
| 383.40 | 3.86 | 3.86 |
| 275.35 | 1.16 | 1.16 |
| 466.99 | 3.43 | 3.43 |
| 259.33 | 3.28 | 3.28 |
| 372.39 | 3.57 | 3.57 |
| 477.57 | 4.26 | 4.26 |
| 337.41 | 2.34 | 2.34 |
| 411.53 | 4.60 | 4.60 |
| 413.44 | 3.25 | 3.25 |
| 363.43 | 2.37 | 2.37 |
| 366.44 | 1.17 | 1.17 |
| 298.13 | 1.57 | 1.57 |
| 432.55 | 5.26 | 5.26 |
| 379.24 | 2.32 | 2.32 |
| 445.59 | 3.04 | 3.04 |
| 217.29 | 3.37 | 3.37 |
| 409.29 | 1.19 | 1.19 |
| 357.40 | 1.91 | 1.91 |
| 339.40 | 4.16 | 4.16 |
| 295.34 | 2.37 | 2.37 |
| 405.39 | 3.41 | 3.41 |
| 412.42 | 5.53 | 5.53 |
| 406.31 | 1.51 | 1.51 |
| 535.44 | 2.40 | 2.40 |
| 325.41 | 3.18 | 3.18 |
| 505.44 | 5.55 | 5.55 |
| 374.46 | 2.58 | 2.58 |
| 281.31 | 4.61 | 4.61 |
| 353.33 | 3.05 | 3.05 |
| 319.36 | 3.17 | 3.17 |
| 302.72 | 3.07 | 3.07 |
| 392.24 | 3.17 | 3.17 |
| 424.82 | 1.36 | 1.36 |
| 548.66 | 4.26 | 4.26 |
| 424.54 | 3.11 | 3.11 |
| 302.80 | 1.12 | 1.12 |
| 395.43 | 3.88 | 3.88 |
| 397.54 | 4.10 | 4.10 |
| 381.48 | 3.16 | 3.16 |
| 316.47 | 3.67 | 3.67 |
| 348.42 | 2.49 | 2.49 |
| 199.30 | 1.96 | 1.96 |
| 274.32 | 1.95 | 1.95 |
| 430.43 | 4.58 | 4.58 |
| 370.19 | 1.77 | 1.77 |
| 385.53 | 3.49 | 3.49 |
| 456.37 | 2.99 | 2.99 |
| 238.40 | 3.94 | 3.94 |
| 431.31 | 2.08 | 2.08 |
| 439.54 | 2.17 | 2.17 |
| 418.32 | 4.34 | 4.34 |
| 122.17 | 0.81 | 0.81 |
| 317.30 | 3.34 | 3.34 |
| 347.39 | 2.87 | 2.87 |
| 396.31 | 2.99 | 2.99 |
| 455.56 | 4.84 | 4.84 |
| 345.20 | 2.46 | 2.46 |
| 438.31 | 2.35 | 2.35 |
| 322.41 | 4.80 | 4.80 |
| 470.64 | 3.18 | 3.18 |
| 385.24 | 2.32 | 2.32 |
| 237.69 | 1.30 | 1.30 |
| 412.56 | 3.07 | 3.07 |
| 342.22 | 2.86 | 2.86 |
| 354.24 | 2.71 | 2.71 |
| 374.31 | 3.03 | 3.03 |
| 438.46 | 3.30 | 3.30 |
| 337.20 | 2.99 | 2.99 |
| 448.88 | 4.18 | 4.18 |
| 399.48 | 2.83 | 2.83 |
| 500.64 | 4.12 | 4.12 |
| 298.35 | 2.50 | 2.50 |
| 511.40 | 2.83 | 2.83 |
| 229.31 | 3.10 | 3.10 |
| 344.24 | 2.35 | 2.35 |
| 536.12 | 5.73 | 5.73 |
| 440.48 | 3.26 | 3.26 |
| 374.70 | 3.54 | 3.54 |
| 468.66 | 3.47 | 3.47 |
| 312.37 | 2.89 | 2.89 |
| 391.52 | 3.73 | 3.73 |
| 321.33 | 1.59 | 1.59 |
| 399.41 | 3.12 | 3.12 |
| 347.28 | 3.51 | 3.51 |
| 439.42 | 3.46 | 3.46 |
| 547.89 | 6.29 | 6.29 |
| 328.30 | 2.12 | 2.12 |
| 329.40 | 4.26 | 4.26 |
| 530.87 | 3.83 | 3.83 |
| 380.26 | 3.90 | 3.90 |
| 362.25 | 2.28 | 2.28 |
| 290.41 | 1.74 | 1.74 |
| 313.40 | 2.64 | 2.64 |
| 345.47 | 2.96 | 2.96 |
| 493.03 | 2.76 | 2.76 |
| 491.61 | 1.96 | 1.96 |
| 451.38 | 4.91 | 4.91 |
| 388.35 | 3.41 | 3.41 |
| 461.35 | 3.64 | 3.64 |
| 539.07 | 3.81 | 3.81 |
| 317.42 | 2.07 | 2.07 |
| 314.34 | 1.96 | 1.96 |
| 359.40 | 2.09 | 2.09 |
| 489.40 | 3.81 | 3.81 |
| 192.17 | 2.28 | 2.28 |
| 409.35 | 3.25 | 3.25 |
| 365.30 | 2.56 | 2.56 |
| 449.53 | 3.72 | 3.72 |
| 392.50 | 3.31 | 3.31 |
| 276.32 | 3.29 | 3.29 |
| 407.25 | 1.33 | 1.33 |
| 434.97 | 4.10 | 4.10 |
| 342.46 | 3.86 | 3.86 |
| 448.91 | 3.87 | 3.87 |
| 382.24 | 2.20 | 2.20 |
| 440.37 | 3.67 | 3.67 |
| 340.38 | 3.59 | 3.59 |
| 374.61 | 2.42 | 2.42 |
| 380.49 | 2.82 | 2.82 |
| 318.40 | 4.28 | 4.28 |
| 446.55 | 1.72 | 1.72 |
| 403.52 | 2.90 | 2.90 |
| 345.36 | 4.15 | 4.15 |
| 537.08 | 2.91 | 2.91 |
| 309.34 | 1.86 | 1.86 |
| 389.93 | 2.43 | 2.43 |
| 338.41 | 3.78 | 3.78 |
| 475.34 | 5.34 | 5.34 |
| 398.42 | 4.51 | 4.51 |
| 479.44 | 3.78 | 3.78 |
| 442.97 | 3.51 | 3.51 |
| 403.30 | 3.31 | 3.31 |
| 333.43 | 1.83 | 1.83 |
| 251.29 | 4.60 | 4.60 |
| 423.87 | 4.31 | 4.31 |
| 437.53 | 2.69 | 2.69 |
| 263.25 | 2.12 | 2.12 |
| 512.08 | 4.53 | 4.53 |
| 425.48 | 3.45 | 3.45 |
| 331.39 | 3.04 | 3.04 |
| 417.33 | 3.16 | 3.16 |
| 294.38 | 3.97 | 3.97 |
| 412.53 | 2.18 | 2.18 |
| 219.24 | 2.01 | 2.01 |
| 398.53 | 1.96 | 1.96 |
| 390.51 | 2.45 | 2.45 |
| 472.41 | 3.61 | 3.61 |
| 457.91 | 3.62 | 3.62 |
| 327.41 | 3.99 | 3.99 |
| 435.52 | 2.56 | 2.56 |
| 326.14 | 1.56 | 1.56 |
| 407.88 | 2.90 | 2.90 |
| 346.43 | 4.49 | 4.49 |
| 431.75 | 3.45 | 3.45 |
| 329.43 | 3.47 | 3.47 |
| 279.32 | 1.49 | 1.49 |
| 416.31 | 4.13 | 4.13 |
| 292.16 | 2.16 | 2.16 |
| 322.32 | 3.26 | 3.26 |
| 316.41 | 0.88 | 0.88 |
| 337.29 | 3.30 | 3.30 |
| 429.87 | 5.29 | 5.29 |
| 269.30 | 3.25 | 3.25 |
| 313.38 | 3.60 | 3.60 |
| 356.77 | 2.58 | 2.58 |
| 304.37 | 3.41 | 3.41 |
| 331.45 | 2.26 | 2.26 |
| 374.23 | 3.23 | 3.23 |
| 271.28 | 1.62 | 1.62 |
| 232.24 | 0.61 | 0.61 |
| 452.78 | 4.26 | 4.26 |
| 349.41 | 2.24 | 2.24 |
| 329.44 | 2.60 | 2.60 |
| 547.61 | 3.44 | 3.44 |
| 290.43 | 3.14 | 3.14 |
| 323.26 | 3.05 | 3.05 |
| 495.45 | 4.72 | 4.72 |
| 363.26 | 3.31 | 3.31 |
| 478.46 | 1.22 | 1.22 |
| 348.36 | 2.76 | 2.76 |
| 491.43 | 3.30 | 3.30 |
| 274.30 | 3.15 | 3.15 |
| 382.29 | 3.80 | 3.80 |
| 468.66 | 3.47 | 3.47 |
| 429.09 | 2.64 | 2.64 |
| 329.23 | 3.45 | 3.45 |
| 443.30 | 2.56 | 2.56 |
| 309.24 | 2.52 | 2.52 |
| 387.51 | 3.31 | 3.31 |
| 327.43 | 2.87 | 2.87 |
| 453.54 | 3.68 | 3.68 |
| 343.38 | 3.26 | 3.26 |
| 405.28 | 1.64 | 1.64 |
| 340.26 | 2.61 | 2.61 |
| 216.24 | 1.67 | 1.67 |
| 328.44 | 3.61 | 3.61 |
| 444.53 | 1.97 | 1.97 |
| 542.70 | 3.61 | 3.61 |
| 332.45 | 2.16 | 2.16 |
| 398.68 | 3.48 | 3.48 |
| 459.51 | 5.31 | 5.31 |
| 466.36 | 3.00 | 3.00 |
| 263.12 | 1.88 | 1.88 |
| 412.70 | 3.96 | 3.96 |
| 333.39 | 2.05 | 2.05 |
| 399.88 | 3.33 | 3.33 |
| 403.41 | 2.52 | 2.52 |
| 409.35 | 3.37 | 3.37 |
| 494.64 | 1.90 | 1.90 |
| 280.37 | 1.38 | 1.38 |
| 386.50 | 1.79 | 1.79 |
| 529.62 | 2.41 | 2.41 |
| 354.19 | 1.44 | 1.44 |
| 400.29 | 2.45 | 2.45 |
| 332.16 | 3.17 | 3.17 |
| 354.41 | 2.88 | 2.88 |
| 480.57 | 2.52 | 2.52 |
| 375.51 | 3.00 | 3.00 |
| 328.19 | 1.28 | 1.28 |
| 440.32 | 1.91 | 1.91 |
| 503.43 | 3.36 | 3.36 |
| 248.71 | 1.76 | 1.76 |
| 463.40 | 4.19 | 4.19 |
| 271.30 | 1.55 | 1.55 |
| 407.41 | -0.13 | -0.13 |
| 522.62 | 3.86 | 3.86 |
| 410.47 | 3.38 | 3.38 |
| 302.31 | 2.69 | 2.69 |
| 484.50 | 1.75 | 1.75 |
| 341.37 | 2.34 | 2.34 |
| 391.41 | 1.73 | 1.73 |
| 393.31 | 2.74 | 2.74 |
| 290.82 | 1.01 | 1.01 |
| 358.94 | 2.67 | 2.67 |
| 318.80 | 2.05 | 2.05 |
| 257.07 | -1.47 | -1.47 |
| 485.39 | 1.28 | 1.28 |
| 346.39 | 0.77 | 0.77 |
| 435.57 | 4.45 | 4.45 |
| 527.47 | 3.41 | 3.41 |
| 368.22 | 2.38 | 2.38 |
| 436.29 | 3.09 | 3.09 |
| 527.36 | 1.94 | 1.94 |
| 305.72 | 3.37 | 3.37 |
| 359.39 | 3.51 | 3.51 |
| 382.42 | 3.35 | 3.35 |
| 383.43 | 2.74 | 2.74 |
| 422.40 | 3.56 | 3.56 |
| 411.20 | 1.00 | 1.00 |
| 325.28 | 0.61 | 0.61 |
| 521.85 | 3.92 | 3.92 |
| 315.33 | 2.30 | 2.30 |
| 317.30 | 2.28 | 2.28 |
| 357.37 | 1.91 | 1.91 |
| 360.40 | 2.63 | 2.63 |
| 353.29 | 2.42 | 2.42 |
| 448.48 | 3.32 | 3.32 |
| 439.34 | 2.57 | 2.57 |
| 436.52 | 3.87 | 3.87 |
| 369.33 | 1.54 | 1.54 |
| 233.23 | 0.48 | 0.48 |
| 372.25 | 1.50 | 1.50 |
| 455.58 | 3.47 | 3.47 |
| 396.24 | 4.45 | 4.45 |
| 378.28 | 3.14 | 3.14 |
| 429.52 | 4.17 | 4.17 |