ID: ALA1738090
Type: Functional
Description: PUBCHEM_BIOASSAY: qHTS Assay for Compounds Blocking the Interaction Between CBF-beta and RUNX1 for the Treatment of Acute Myeloid Leukemia: Hit Validation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1477, AID1484]
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA1738090
Potency
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
302.19 | 1.31 | 1.31 |
288.30 | 2.12 | 2.12 |
422.35 | 2.45 | 2.45 |
169.18 | 0.09 | 0.09 |
167.12 | 0.48 | 0.48 |
179.22 | 2.12 | 2.12 |
563.65 | 6.00 | 6.00 |
394.32 | 4.13 | 4.13 |
156.19 | 2.14 | 2.14 |
180.21 | 2.78 | 2.78 |
782.53 | 0.02 | 0.02 |
174.16 | 1.33 | 1.33 |
296.55 | 3.62 | 3.62 |
338.31 | 1.88 | 1.88 |
220.18 | 1.02 | 1.02 |
126.11 | 0.80 | 0.80 |
274.37 | 3.67 | 3.67 |
314.25 | 2.82 | 2.82 |
213.19 | -0.24 | -0.24 |
523.74 | 6.49 | 6.49 |
414.60 | 4.99 | 4.99 |
287.36 | 1.92 | 1.92 |
169.18 | 0.30 | 0.30 |
197.19 | 0.05 | 0.05 |
472.36 | 2.23 | 2.23 |
204.30 | 2.95 | 2.95 |
543.87 | 6.47 | 6.47 |
301.35 | 2.60 | 2.60 |
197.19 | 0.05 | 0.05 |
223.24 | 1.93 | 1.93 |
205.64 | 0.30 | 0.30 |
331.42 | 4.35 | 4.35 |
697.14 | 5.37 | 5.37 |
485.49 | 0.97 | 0.97 |
168.15 | 1.22 | 1.22 |
178.22 | 1.47 | 1.47 |
341.20 | 3.86 | 3.86 |
362.39 | 3.88 | 3.88 |
862.75 | -1.10 | -1.10 |
292.36 | 3.70 | 3.70 |
425.10 | 4.27 | 4.27 |
380.35 | 3.70 | 3.70 |
382.89 | 5.28 | 5.28 |
365.83 | 3.33 | 3.33 |
260.21 | 2.34 | 2.34 |
315.17 | 4.73 | 4.73 |
280.36 | 3.23 | 3.23 |
419.44 | 3.13 | 3.13 |
356.54 | 4.24 | 4.24 |
472.63 | 4.40 | 4.40 |
350.44 | 4.37 | 4.37 |
376.96 | 4.59 | 4.59 |
395.71 | 5.46 | 5.46 |
185.23 | 2.53 | 2.53 |
352.25 | 4.04 | 4.04 |
285.74 | 3.09 | 3.09 |
409.49 | 1.94 | 1.94 |
561.68 | 2.04 | 2.04 |
402.54 | 6.48 | 6.48 |
956.68 | 0.02 | 0.02 |
285.30 | 2.75 | 2.75 |
360.80 | -0.80 | -0.80 |
611.74 | 2.72 | 2.72 |
350.45 | 4.55 | 4.55 |
346.48 | 3.76 | 3.76 |
575.71 | 2.43 | 2.43 |
358.37 | 5.79 | 5.79 |
203.24 | 2.43 | 2.43 |
302.40 | 2.28 | 2.28 |
342.51 | 3.93 | 3.93 |
450.99 | 3.37 | 3.37 |
322.32 | 2.77 | 2.77 |
634.46 | -0.30 | -0.30 |
342.51 | 3.93 | 3.93 |
245.27 | 1.15 | 1.15 |
459.55 | 3.84 | 3.84 |
318.59 | 4.33 | 4.33 |
288.35 | 3.72 | 3.72 |
318.24 | 1.69 | 1.69 |
329.81 | 4.19 | 4.19 |
570.46 | 3.01 | 3.01 |
382.45 | 3.29 | 3.29 |
442.42 | 0.56 | 0.56 |
408.40 | 1.79 | 1.79 |
206.27 | 2.40 | 2.40 |
336.42 | 2.95 | 2.95 |
332.44 | 3.72 | 3.72 |
457.49 | 2.83 | 2.83 |
376.96 | 4.59 | 4.59 |
372.84 | 4.51 | 4.51 |
232.31 | 2.50 | 2.50 |
273.31 | 3.95 | 3.95 |
277.71 | 1.80 | 1.80 |
234.26 | 2.60 | 2.60 |
409.43 | 4.89 | 4.89 |
395.71 | 5.46 | 5.46 |
204.20 | 2.60 | 2.60 |
309.33 | 3.35 | 3.35 |
279.73 | 2.33 | 2.33 |
304.35 | 3.14 | 3.14 |
324.42 | 4.45 | 4.45 |
290.33 | 5.55 | 5.55 |
281.34 | 4.20 | 4.20 |
305.18 | 2.82 | 2.82 |
388.33 | 1.90 | 1.90 |
173.17 | 1.75 | 1.75 |
411.44 | 3.17 | 3.17 |
283.29 | 0.52 | 0.52 |
226.30 | 0.99 | 0.99 |
940.68 | 1.69 | 1.69 |
293.28 | 1.69 | 1.69 |
356.54 | 4.19 | 4.19 |
247.28 | 1.72 | 1.72 |
218.32 | 3.26 | 3.26 |
182.22 | 1.21 | 1.21 |
359.38 | 3.45 | 3.45 |
255.30 | 4.42 | 4.42 |
366.45 | 3.67 | 3.67 |
244.32 | 0.80 | 0.80 |
319.32 | 0.56 | 0.56 |
245.28 | 2.23 | 2.23 |
196.20 | 1.79 | 1.79 |
468.50 | -0.47 | -0.47 |
422.08 | 5.46 | 5.46 |
275.27 | 2.73 | 2.73 |
270.34 | 4.90 | 4.90 |
313.33 | 3.59 | 3.59 |
359.40 | 2.09 | 2.09 |
356.54 | 4.24 | 4.24 |
371.42 | 3.92 | 3.92 |
188.61 | 0.55 | 0.55 |
346.89 | 2.00 | 2.00 |
519.06 | 4.74 | 4.74 |
277.33 | 2.67 | 2.67 |
442.42 | -0.44 | -0.44 |
208.22 | 1.05 | 1.05 |
424.55 | 6.76 | 6.76 |
312.37 | 3.55 | 3.55 |
329.74 | 2.00 | 2.00 |
214.09 | 3.06 | 3.06 |
267.28 | 3.24 | 3.24 |
305.31 | 0.93 | 0.93 |
311.41 | 4.61 | 4.61 |
350.43 | -1.23 | -1.23 |
461.54 | 5.13 | 5.13 |
108.14 | 0.85 | 0.85 |
399.50 | 5.53 | 5.53 |
331.42 | 4.11 | 4.11 |
330.42 | 5.96 | 5.96 |
278.17 | 0.72 | 0.72 |
255.32 | 2.79 | 2.79 |
354.45 | 2.95 | 2.95 |
461.82 | 3.15 | 3.15 |
317.43 | 3.21 | 3.21 |
338.39 | 1.50 | 1.50 |
347.41 | 2.43 | 2.43 |
267.33 | 4.21 | 4.21 |
305.83 | 3.69 | 3.69 |
346.32 | 1.37 | 1.37 |
304.37 | 3.81 | 3.81 |
395.17 | 2.23 | 2.23 |
368.33 | 0.80 | 0.80 |
403.48 | 4.25 | 4.25 |
235.67 | 2.13 | 2.13 |
282.68 | 1.92 | 1.92 |
282.30 | 2.72 | 2.72 |
284.32 | 1.00 | 1.00 |
499.96 | 2.30 | 2.30 |
413.39 | 4.09 | 4.09 |
359.38 | 2.89 | 2.89 |
478.89 | -0.44 | -0.44 |
269.35 | 2.75 | 2.75 |
298.25 | 1.43 | 1.43 |
403.51 | 2.73 | 2.73 |
316.41 | 3.39 | 3.39 |
370.35 | 2.15 | 2.15 |
400.95 | 4.04 | 4.04 |
310.38 | 3.68 | 3.68 |
321.42 | 3.78 | 3.78 |
293.31 | 1.31 | 1.31 |
293.12 | 2.39 | 2.39 |
242.23 | 1.81 | 1.81 |
204.19 | 0.35 | 0.35 |
304.33 | 1.52 | 1.52 |
294.76 | 3.94 | 3.94 |
400.95 | 4.04 | 4.04 |
303.28 | 0.96 | 0.96 |
295.37 | 2.82 | 2.82 |
288.33 | 1.81 | 1.81 |
277.29 | 1.79 | 1.79 |
403.48 | 4.25 | 4.25 |
330.80 | 4.03 | 4.03 |
321.41 | 3.57 | 3.57 |
337.41 | 3.18 | 3.18 |
425.39 | 4.66 | 4.66 |
333.40 | 3.23 | 3.23 |
271.31 | 2.10 | 2.10 |