Basic Information
ID: ALA1738090
Type: Functional
Description: PUBCHEM_BIOASSAY: qHTS Assay for Compounds Blocking the Interaction Between CBF-beta and RUNX1 for the Treatment of Acute Myeloid Leukemia: Hit Validation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1477, AID1484]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1738090
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 302.19 | 1.31 | 1.31 |
| 288.30 | 2.12 | 2.12 |
| 422.35 | 2.45 | 2.45 |
| 169.18 | 0.09 | 0.09 |
| 167.12 | 0.48 | 0.48 |
| 179.22 | 2.12 | 2.12 |
| 563.65 | 6.00 | 6.00 |
| 394.32 | 4.13 | 4.13 |
| 156.19 | 2.14 | 2.14 |
| 180.21 | 2.78 | 2.78 |
| 782.53 | 0.02 | 0.02 |
| 174.16 | 1.33 | 1.33 |
| 296.55 | 3.62 | 3.62 |
| 338.31 | 1.88 | 1.88 |
| 220.18 | 1.02 | 1.02 |
| 126.11 | 0.80 | 0.80 |
| 274.37 | 3.67 | 3.67 |
| 314.25 | 2.82 | 2.82 |
| 213.19 | -0.24 | -0.24 |
| 523.74 | 6.49 | 6.49 |
| 414.60 | 4.99 | 4.99 |
| 287.36 | 1.92 | 1.92 |
| 169.18 | 0.30 | 0.30 |
| 197.19 | 0.05 | 0.05 |
| 472.36 | 2.23 | 2.23 |
| 204.30 | 2.95 | 2.95 |
| 543.87 | 6.47 | 6.47 |
| 301.35 | 2.60 | 2.60 |
| 197.19 | 0.05 | 0.05 |
| 223.24 | 1.93 | 1.93 |
| 205.64 | 0.30 | 0.30 |
| 331.42 | 4.35 | 4.35 |
| 697.14 | 5.37 | 5.37 |
| 485.49 | 0.97 | 0.97 |
| 168.15 | 1.22 | 1.22 |
| 178.22 | 1.47 | 1.47 |
| 341.20 | 3.86 | 3.86 |
| 362.39 | 3.88 | 3.88 |
| 862.75 | -1.10 | -1.10 |
| 292.36 | 3.70 | 3.70 |
| 425.10 | 4.27 | 4.27 |
| 380.35 | 3.70 | 3.70 |
| 382.89 | 5.28 | 5.28 |
| 365.83 | 3.33 | 3.33 |
| 260.21 | 2.34 | 2.34 |
| 315.17 | 4.73 | 4.73 |
| 280.36 | 3.23 | 3.23 |
| 419.44 | 3.13 | 3.13 |
| 356.54 | 4.24 | 4.24 |
| 472.63 | 4.40 | 4.40 |
| 350.44 | 4.37 | 4.37 |
| 376.96 | 4.59 | 4.59 |
| 395.71 | 5.46 | 5.46 |
| 185.23 | 2.53 | 2.53 |
| 352.25 | 4.04 | 4.04 |
| 285.74 | 3.09 | 3.09 |
| 409.49 | 1.94 | 1.94 |
| 561.68 | 2.04 | 2.04 |
| 402.54 | 6.48 | 6.48 |
| 956.68 | 0.02 | 0.02 |
| 285.30 | 2.75 | 2.75 |
| 360.80 | -0.80 | -0.80 |
| 611.74 | 2.72 | 2.72 |
| 350.45 | 4.55 | 4.55 |
| 346.48 | 3.76 | 3.76 |
| 575.71 | 2.43 | 2.43 |
| 358.37 | 5.79 | 5.79 |
| 203.24 | 2.43 | 2.43 |
| 302.40 | 2.28 | 2.28 |
| 342.51 | 3.93 | 3.93 |
| 450.99 | 3.37 | 3.37 |
| 322.32 | 2.77 | 2.77 |
| 634.46 | -0.30 | -0.30 |
| 342.51 | 3.93 | 3.93 |
| 245.27 | 1.15 | 1.15 |
| 459.55 | 3.84 | 3.84 |
| 318.59 | 4.33 | 4.33 |
| 288.35 | 3.72 | 3.72 |
| 318.24 | 1.69 | 1.69 |
| 329.81 | 4.19 | 4.19 |
| 570.46 | 3.01 | 3.01 |
| 382.45 | 3.29 | 3.29 |
| 442.42 | 0.56 | 0.56 |
| 408.40 | 1.79 | 1.79 |
| 206.27 | 2.40 | 2.40 |
| 336.42 | 2.95 | 2.95 |
| 332.44 | 3.72 | 3.72 |
| 457.49 | 2.83 | 2.83 |
| 376.96 | 4.59 | 4.59 |
| 372.84 | 4.51 | 4.51 |
| 232.31 | 2.50 | 2.50 |
| 273.31 | 3.95 | 3.95 |
| 277.71 | 1.80 | 1.80 |
| 234.26 | 2.60 | 2.60 |
| 409.43 | 4.89 | 4.89 |
| 395.71 | 5.46 | 5.46 |
| 204.20 | 2.60 | 2.60 |
| 309.33 | 3.35 | 3.35 |
| 279.73 | 2.33 | 2.33 |
| 304.35 | 3.14 | 3.14 |
| 324.42 | 4.45 | 4.45 |
| 290.33 | 5.55 | 5.55 |
| 281.34 | 4.20 | 4.20 |
| 305.18 | 2.82 | 2.82 |
| 388.33 | 1.90 | 1.90 |
| 173.17 | 1.75 | 1.75 |
| 411.44 | 3.17 | 3.17 |
| 283.29 | 0.52 | 0.52 |
| 226.30 | 0.99 | 0.99 |
| 940.68 | 1.69 | 1.69 |
| 293.28 | 1.69 | 1.69 |
| 356.54 | 4.19 | 4.19 |
| 247.28 | 1.72 | 1.72 |
| 218.32 | 3.26 | 3.26 |
| 182.22 | 1.21 | 1.21 |
| 359.38 | 3.45 | 3.45 |
| 255.30 | 4.42 | 4.42 |
| 366.45 | 3.67 | 3.67 |
| 244.32 | 0.80 | 0.80 |
| 319.32 | 0.56 | 0.56 |
| 245.28 | 2.23 | 2.23 |
| 196.20 | 1.79 | 1.79 |
| 468.50 | -0.47 | -0.47 |
| 422.08 | 5.46 | 5.46 |
| 275.27 | 2.73 | 2.73 |
| 270.34 | 4.90 | 4.90 |
| 313.33 | 3.59 | 3.59 |
| 359.40 | 2.09 | 2.09 |
| 356.54 | 4.24 | 4.24 |
| 371.42 | 3.92 | 3.92 |
| 188.61 | 0.55 | 0.55 |
| 346.89 | 2.00 | 2.00 |
| 519.06 | 4.74 | 4.74 |
| 277.33 | 2.67 | 2.67 |
| 442.42 | -0.44 | -0.44 |
| 208.22 | 1.05 | 1.05 |
| 424.55 | 6.76 | 6.76 |
| 312.37 | 3.55 | 3.55 |
| 329.74 | 2.00 | 2.00 |
| 214.09 | 3.06 | 3.06 |
| 267.28 | 3.24 | 3.24 |
| 305.31 | 0.93 | 0.93 |
| 311.41 | 4.61 | 4.61 |
| 350.43 | -1.23 | -1.23 |
| 461.54 | 5.13 | 5.13 |
| 108.14 | 0.85 | 0.85 |
| 399.50 | 5.53 | 5.53 |
| 331.42 | 4.11 | 4.11 |
| 330.42 | 5.96 | 5.96 |
| 278.17 | 0.72 | 0.72 |
| 255.32 | 2.79 | 2.79 |
| 354.45 | 2.95 | 2.95 |
| 461.82 | 3.15 | 3.15 |
| 317.43 | 3.21 | 3.21 |
| 338.39 | 1.50 | 1.50 |
| 347.41 | 2.43 | 2.43 |
| 267.33 | 4.21 | 4.21 |
| 305.83 | 3.69 | 3.69 |
| 346.32 | 1.37 | 1.37 |
| 304.37 | 3.81 | 3.81 |
| 395.17 | 2.23 | 2.23 |
| 368.33 | 0.80 | 0.80 |
| 403.48 | 4.25 | 4.25 |
| 235.67 | 2.13 | 2.13 |
| 282.68 | 1.92 | 1.92 |
| 282.30 | 2.72 | 2.72 |
| 284.32 | 1.00 | 1.00 |
| 499.96 | 2.30 | 2.30 |
| 413.39 | 4.09 | 4.09 |
| 359.38 | 2.89 | 2.89 |
| 478.89 | -0.44 | -0.44 |
| 269.35 | 2.75 | 2.75 |
| 298.25 | 1.43 | 1.43 |
| 403.51 | 2.73 | 2.73 |
| 316.41 | 3.39 | 3.39 |
| 370.35 | 2.15 | 2.15 |
| 400.95 | 4.04 | 4.04 |
| 310.38 | 3.68 | 3.68 |
| 321.42 | 3.78 | 3.78 |
| 293.31 | 1.31 | 1.31 |
| 293.12 | 2.39 | 2.39 |
| 242.23 | 1.81 | 1.81 |
| 204.19 | 0.35 | 0.35 |
| 304.33 | 1.52 | 1.52 |
| 294.76 | 3.94 | 3.94 |
| 400.95 | 4.04 | 4.04 |
| 303.28 | 0.96 | 0.96 |
| 295.37 | 2.82 | 2.82 |
| 288.33 | 1.81 | 1.81 |
| 277.29 | 1.79 | 1.79 |
| 403.48 | 4.25 | 4.25 |
| 330.80 | 4.03 | 4.03 |
| 321.41 | 3.57 | 3.57 |
| 337.41 | 3.18 | 3.18 |
| 425.39 | 4.66 | 4.66 |
| 333.40 | 3.23 | 3.23 |
| 271.31 | 2.10 | 2.10 |