Basic Information
ID: ALA1738091
Type: Functional
Description: PUBCHEM_BIOASSAY: HTS Assay for Allosteric Agonists of the Human D1 Dopamine Receptor: Primary Screen for Potentiators. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488989, AID488993, AID488995]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1738091
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 162.24 | 1.85 | 1.85 |
| 160.22 | 1.67 | 1.67 |
| 202.26 | 1.82 | 1.82 |
| 264.37 | 3.08 | 3.08 |
| 280.42 | 3.88 | 3.88 |
| 249.35 | 2.15 | 2.15 |
| 391.56 | 6.86 | 6.86 |
| 314.86 | 4.53 | 4.53 |
| 231.09 | 1.81 | 1.81 |
| 414.53 | 3.37 | 3.37 |
| 266.34 | 0.45 | 0.45 |
| 407.51 | 4.95 | 4.95 |
| 341.43 | 0.56 | 0.56 |
| 169.18 | 0.09 | 0.09 |
| 206.29 | 0.71 | 0.71 |
| 326.83 | 3.54 | 3.54 |
| 326.83 | 3.72 | 3.72 |
| 263.38 | 3.83 | 3.83 |
| 393.47 | 4.51 | 4.51 |
| 219.33 | 2.98 | 2.98 |
| 385.51 | 2.09 | 2.09 |
| 302.24 | 1.99 | 1.99 |
| 395.43 | 2.42 | 2.42 |
| 276.38 | 1.96 | 1.96 |
| 267.33 | 2.85 | 2.85 |
| 375.87 | 4.43 | 4.43 |
| 393.49 | 2.89 | 2.89 |
| 361.53 | 4.84 | 4.84 |
| 153.18 | 0.60 | 0.60 |
| 341.43 | 0.56 | 0.56 |
| 287.79 | 3.67 | 3.67 |
| 192.26 | 1.10 | 1.10 |
| 318.87 | 4.89 | 4.89 |
| 266.39 | 3.53 | 3.53 |
| 351.41 | 1.56 | 1.56 |
| 473.59 | 6.08 | 6.08 |
| 371.52 | 6.00 | 6.00 |
| 654.61 | 3.19 | 3.19 |
| 299.80 | 2.00 | 2.00 |
| 285.39 | 2.66 | 2.66 |
| 477.58 | 5.48 | 5.48 |
| 103.12 | -0.19 | -0.19 |
| 287.41 | 4.70 | 4.70 |
| 308.38 | 3.79 | 3.79 |
| 314.50 | 4.27 | 4.27 |
| 309.43 | 4.01 | 4.01 |
| 211.66 | 1.17 | 1.17 |
| 298.35 | 1.38 | 1.38 |
| 394.86 | 5.13 | 5.13 |
| 409.42 | 4.79 | 4.79 |
| 354.45 | 2.65 | 2.65 |
| 179.26 | 2.03 | 2.03 |
| 284.43 | 4.24 | 4.24 |
| 497.60 | 5.03 | 5.03 |
| 403.98 | 3.94 | 3.94 |
| 352.43 | 5.26 | 5.26 |
| 237.34 | 2.76 | 2.76 |
| 129.16 | 0.07 | 0.07 |
| 285.69 | 2.77 | 2.77 |
| 345.37 | 2.56 | 2.56 |
| 360.35 | 4.85 | 4.85 |
| 305.76 | 2.73 | 2.73 |
| 471.69 | 6.45 | 6.45 |
| 281.36 | 2.84 | 2.84 |
| 190.25 | 1.64 | 1.64 |
| 190.25 | 1.76 | 1.76 |
| 163.20 | -0.49 | -0.49 |
| 393.46 | 3.28 | 3.28 |
| 203.25 | 0.77 | 0.77 |
| 212.30 | 2.25 | 2.25 |
| 283.33 | 2.56 | 2.56 |
| 403.53 | 4.06 | 4.06 |
| 250.30 | 0.72 | 0.72 |
| 371.87 | 2.36 | 2.36 |
| 277.41 | 4.17 | 4.17 |
| 284.43 | 4.24 | 4.24 |
| 294.44 | 4.12 | 4.12 |
| 277.41 | 4.21 | 4.21 |
| 263.38 | 4.30 | 4.30 |
| 275.40 | 4.55 | 4.55 |
| 459.41 | 5.17 | 5.17 |
| 183.21 | 0.35 | 0.35 |
| 320.43 | 5.17 | 5.17 |
| 382.46 | 2.86 | 2.86 |
| 213.66 | 1.86 | 1.86 |
| 451.48 | 1.72 | 1.72 |
| 345.40 | 2.51 | 2.51 |
| 417.55 | 4.18 | 4.18 |
| 272.69 | 2.72 | 2.72 |
| 211.22 | 0.44 | 0.44 |
| 414.59 | 5.04 | 5.04 |
| 179.22 | 0.91 | 0.91 |
| 334.35 | 3.26 | 3.26 |
| 406.48 | 3.74 | 3.74 |
| 437.53 | 4.31 | 4.31 |
| 373.95 | 4.58 | 4.58 |
| 197.13 | -0.64 | -0.64 |
| 256.10 | 2.01 | 2.01 |
| 550.76 | 5.98 | 5.98 |
| 347.86 | 4.47 | 4.47 |
| 542.42 | 4.16 | 4.16 |
| 187.17 | 0.23 | 0.23 |
| 434.52 | 3.70 | 3.70 |
| 302.24 | 1.99 | 1.99 |
| 167.21 | 0.86 | 0.86 |
| 247.32 | 2.39 | 2.39 |
| 374.28 | 4.04 | 4.04 |
| 329.83 | 3.93 | 3.93 |
| 295.38 | 3.27 | 3.27 |
| 276.21 | 3.21 | 3.21 |
| 306.24 | 5.18 | 5.18 |
| 317.23 | 3.84 | 3.84 |
| 361.83 | 3.55 | 3.55 |
| 183.16 | 0.18 | 0.18 |
| 258.28 | 1.55 | 1.55 |
| 340.49 | 4.83 | 4.83 |
| 327.81 | 3.77 | 3.77 |
| 329.44 | 3.26 | 3.26 |
| 127.14 | -0.01 | -0.01 |
| 180.25 | 1.15 | 1.15 |
| 292.34 | 3.17 | 3.17 |
| 278.40 | 3.92 | 3.92 |
| 279.38 | 3.96 | 3.96 |
| 475.58 | 5.31 | 5.31 |
| 271.36 | 3.42 | 3.42 |
| 334.42 | 2.38 | 2.38 |
| 370.46 | 5.59 | 5.59 |
| 399.62 | 4.23 | 4.23 |
| 239.75 | 3.30 | 3.30 |
| 327.18 | 4.09 | 4.09 |
| 434.53 | 4.60 | 4.60 |
| 247.38 | 3.37 | 3.37 |
| 301.39 | 2.96 | 2.96 |
| 390.52 | 3.95 | 3.95 |
| 504.64 | -0.02 | -0.02 |
| 255.36 | 3.72 | 3.72 |
| 271.40 | 3.33 | 3.33 |
| 340.85 | 4.30 | 4.30 |
| 418.28 | 3.49 | 3.49 |
| 389.89 | 1.23 | 1.23 |
| 216.28 | 1.77 | 1.77 |
| 296.55 | 3.62 | 3.62 |
| 291.44 | 4.56 | 4.56 |
| 331.80 | 3.33 | 3.33 |
| 344.91 | 4.34 | 4.34 |
| 290.41 | 3.79 | 3.79 |
| 448.44 | 1.65 | 1.65 |
| 307.40 | 2.77 | 2.77 |
| 325.45 | 3.77 | 3.77 |
| 449.64 | 4.85 | 4.85 |
| 339.48 | 4.02 | 4.02 |
| 244.25 | 2.68 | 2.68 |
| 350.46 | 4.15 | 4.15 |
| 469.67 | 7.22 | 7.22 |
| 279.34 | 0.98 | 0.98 |
| 127.14 | -0.01 | -0.01 |
| 186.17 | 1.53 | 1.53 |
| 282.39 | 4.42 | 4.42 |
| 218.30 | 1.76 | 1.76 |
| 307.43 | 4.01 | 4.01 |
| 417.63 | 7.05 | 7.05 |
| 131.18 | 0.59 | 0.59 |
| 353.47 | 1.94 | 1.94 |
| 271.32 | 2.41 | 2.41 |
| 161.66 | 2.23 | 2.23 |
| 129.16 | 0.36 | 0.36 |
| 376.39 | 0.53 | 0.53 |
| 302.37 | 3.57 | 3.57 |
| 650.76 | 3.93 | 3.93 |
| 249.32 | 2.47 | 2.47 |
| 286.36 | 3.59 | 3.59 |
| 293.37 | 3.41 | 3.41 |
| 356.56 | 4.40 | 4.40 |
| 313.79 | 3.43 | 3.43 |
| 497.50 | 1.02 | 1.02 |
| 391.47 | 4.88 | 4.88 |
| 202.39 | 1.96 | 1.96 |
| 371.22 | 4.05 | 4.05 |
| 130.22 | 0.83 | 0.83 |
| 399.56 | 5.72 | 5.72 |
| 309.45 | 4.20 | 4.20 |
| 42.39 | ||
| 359.73 | 2.43 | 2.43 |
| 386.41 | -0.33 | -0.33 |
| 195.69 | 2.37 | 2.37 |
| 152.15 | 0.00 | 0.00 |
| 212.21 | 1.31 | 1.31 |
| 277.28 | 4.42 | 4.42 |
| 553.28 | -0.91 | -0.91 |
| 304.25 | 1.19 | 1.19 |
| 357.49 | 3.34 | 3.34 |
| 416.95 | 4.61 | 4.61 |
| 392.50 | 3.41 | 3.41 |
| 292.21 | 4.79 | 4.79 |
| 200.28 | 2.11 | 2.11 |
| 281.36 | 3.15 | 3.15 |
| 91.07 | -1.04 | -1.04 |
| 244.29 | 2.29 | 2.29 |
| 324.44 | 3.60 | 3.60 |
| 356.18 | 5.18 | 5.18 |
| 289.76 | 3.03 | 3.03 |
| 355.99 | 2.78 | 2.78 |
| 596.43 | 6.73 | 6.73 |
| 363.50 | 3.31 | 3.31 |
| 361.46 | 3.23 | 3.23 |
| 244.24 | 3.42 | 3.42 |
| 395.42 | 2.53 | 2.53 |
| 305.29 | 3.12 | 3.12 |
| 305.73 | 1.07 | 1.07 |
| 319.76 | 0.54 | 0.54 |
| 461.56 | 5.86 | 5.86 |
| 425.92 | 3.35 | 3.35 |
| 444.44 | -0.35 | -0.35 |
| 169.18 | 0.09 | 0.09 |
| 433.72 | 4.61 | 4.61 |
| 295.38 | 3.63 | 3.63 |
| 451.68 | 5.28 | 5.28 |
| 327.12 | 3.86 | 3.86 |
| 210.28 | 0.07 | 0.07 |
| 481.68 | 6.23 | 6.23 |
| 178.14 | 1.20 | 1.20 |
| 380.35 | -2.04 | -2.04 |
| 479.53 | 3.68 | 3.68 |
| 376.91 | 3.62 | 3.62 |
| 310.40 | 1.73 | 1.73 |
| 416.28 | 2.43 | 2.43 |
| 417.63 | 6.79 | 6.79 |
| 346.34 | 2.18 | 2.18 |
| 370.48 | 2.53 | 2.53 |
| 248.31 | 1.96 | 1.96 |
| 459.59 | 5.34 | 5.34 |
| 395.54 | 4.55 | 4.55 |
| 308.34 | 2.88 | 2.88 |
| 249.34 | 2.80 | 2.80 |
| 360.37 | 2.57 | 2.57 |
| 373.50 | 3.64 | 3.64 |
| 308.30 | -1.84 | -1.84 |
| 426.49 | 3.08 | 3.08 |
| 220.25 | 1.29 | 1.29 |
| 415.42 | -1.13 | -1.13 |
| 244.27 | 1.15 | 1.15 |
| 406.96 | 4.66 | 4.66 |
| 583.69 | 2.08 | 2.08 |
| 376.58 | 5.66 | 5.66 |
| 183.21 | 0.35 | 0.35 |
| 317.82 | 3.68 | 3.68 |
| 496.68 | 3.80 | 3.80 |
| 611.74 | 2.72 | 2.72 |
| 401.50 | 4.22 | 4.22 |
| 452.56 | 3.91 | 3.91 |
| 211.26 | 1.13 | 1.13 |
| 836.39 | -2.45 | -2.45 |
| 328.36 | 4.43 | 4.43 |
| 339.48 | 3.97 | 3.97 |
| 648.85 | 6.38 | 6.38 |
| 269.34 | 2.72 | 2.72 |
| 319.25 | 3.93 | 3.93 |
| 339.44 | 1.92 | 1.92 |
| 1031.00 | ||
| 175.14 | 2.19 | 2.19 |
| 212.63 | 2.01 | 2.01 |
| 235.34 | 2.95 | 2.95 |
| 277.23 | 0.60 | 0.60 |
| 349.40 | 3.65 | 3.65 |
| 292.46 | 4.55 | 4.55 |
| 290.45 | 4.75 | 4.75 |
| 398.42 | 2.91 | 2.91 |
| 466.48 | 0.42 | 0.42 |
| 339.44 | 3.25 | 3.25 |
| 437.19 | 3.21 | 3.21 |
| 376.42 | 2.35 | 2.35 |
| 370.42 | 2.45 | 2.45 |
| 429.60 | 5.41 | 5.41 |
| 543.51 | 0.23 | 0.23 |
| 184.19 | 0.43 | 0.43 |
| 336.56 | 7.30 | 7.30 |
| 315.87 | 5.19 | 5.19 |
| 213.66 | 1.38 | 1.38 |
| 230.34 | 2.75 | 2.75 |
| 230.31 | 2.68 | 2.68 |
| 282.47 | 6.11 | 6.11 |
| 489.59 | 5.17 | 5.17 |
| 467.42 | 3.81 | 3.81 |
| 268.23 | 0.97 | 0.97 |
| 98.10 | -0.10 | -0.10 |
| 394.49 | 4.04 | 4.04 |
| 379.44 | 3.89 | 3.89 |
| 335.30 | 1.99 | 1.99 |
| 226.23 | -0.05 | -0.05 |
| 186.26 | 2.01 | 2.01 |
| 350.47 | 5.16 | 5.16 |
| 473.30 | -1.02 | -1.02 |
| 250.26 | 1.87 | 1.87 |
| 301.52 | 4.15 | 4.15 |
| 201.22 | 1.64 | 1.64 |
| 230.68 | 1.90 | 1.90 |
| 508.45 | 5.68 | 5.68 |
| 332.53 | 4.99 | 4.99 |
| 261.35 | 2.74 | 2.74 |
| 448.55 | 0.94 | 0.94 |
| 231.34 | 2.91 | 2.91 |
| 645.75 | 0.65 | 0.65 |
| 314.21 | 3.78 | 3.78 |
| 337.81 | 4.79 | 4.79 |
| 875.11 | 5.60 | 5.60 |