Basic Information
ID: ALA1738131
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose Response selectivity of uHTS chemical inhibitors of B-cell specific antigen receptor-induced NF-kB activation in Jurkat cells using a luminescence assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID435022, AID435025, AID465]
Cell type: Jurkat
Activity Charts
Bioactivity
Activity Types for Assay ALA1738131
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 280.36 | 1.96 | 1.96 |
| 454.70 | 7.30 | 7.30 |
| 514.63 | 7.26 | 7.26 |
| 418.40 | 3.22 | 3.22 |
| 296.20 | -0.80 | -0.80 |
| 249.32 | 3.28 | 3.28 |
| 312.80 | 4.29 | 4.29 |
| 372.42 | 2.99 | 2.99 |
| 456.55 | 4.01 | 4.01 |
| 239.32 | 2.86 | 2.86 |
| 236.23 | 2.14 | 2.14 |
| 242.23 | 3.22 | 3.22 |
| 414.51 | 3.63 | 3.63 |
| 382.46 | 3.01 | 3.01 |
| 383.75 | 4.69 | 4.69 |
| 349.31 | 4.04 | 4.04 |
| 373.32 | 3.85 | 3.85 |
| 300.36 | 2.14 | 2.14 |
| 317.65 | 3.40 | 3.40 |
| 387.35 | 4.24 | 4.24 |
| 402.45 | 4.86 | 4.86 |
| 637.04 | 5.55 | 5.55 |
| 261.67 | -1.63 | -1.63 |
| 353.42 | 3.88 | 3.88 |
| 307.31 | 2.67 | 2.67 |
| 425.47 | 2.67 | 2.67 |
| 416.45 | 4.05 | 4.05 |
| 466.57 | 2.17 | 2.17 |
| 456.55 | 4.01 | 4.01 |
| 383.88 | 3.03 | 3.03 |
| 323.40 | 2.37 | 2.37 |
| 341.46 | 4.12 | 4.12 |
| 518.04 | 3.23 | 3.23 |
| 314.41 | 3.37 | 3.37 |
| 339.44 | 4.34 | 4.34 |
| 530.67 | 3.33 | 3.33 |
| 331.40 | 2.25 | 2.25 |
| 413.36 | 4.56 | 4.56 |
| 458.56 | 4.03 | 4.03 |
| 497.60 | 4.61 | 4.61 |
| 310.31 | 2.67 | 2.67 |
| 469.47 | 2.70 | 2.70 |
| 412.54 | 4.32 | 4.32 |
| 333.39 | 2.24 | 2.24 |
| 350.42 | 4.00 | 4.00 |
| 345.47 | 1.89 | 1.89 |
| 440.55 | 4.18 | 4.18 |
| 461.52 | 4.27 | 4.27 |
| 382.49 | 3.11 | 3.11 |
| 259.26 | 2.47 | 2.47 |
| 403.49 | 3.22 | 3.22 |
| 378.43 | 2.74 | 2.74 |
| 328.36 | 3.38 | 3.38 |
| 335.77 | 2.37 | 2.37 |
| 332.43 | 1.97 | 1.97 |
| 316.36 | 3.10 | 3.10 |
| 328.37 | 1.59 | 1.59 |
| 269.30 | 2.87 | 2.87 |
| 408.48 | 4.40 | 4.40 |
| 340.38 | 2.62 | 2.62 |
| 358.79 | 2.89 | 2.89 |
| 374.44 | 3.86 | 3.86 |
| 391.27 | 2.71 | 2.71 |
| 306.75 | 2.39 | 2.39 |
| 440.55 | 4.18 | 4.18 |
| 348.54 | 3.96 | 3.96 |
| 328.41 | 2.71 | 2.71 |
| 454.48 | 1.91 | 1.91 |
| 307.31 | 3.45 | 3.45 |
| 333.82 | 3.77 | 3.77 |
| 422.51 | 3.98 | 3.98 |
| 354.43 | 4.24 | 4.24 |
| 441.55 | 6.41 | 6.41 |
| 442.52 | 3.62 | 3.62 |
| 422.29 | 4.44 | 4.44 |
| 371.37 | 2.32 | 2.32 |
| 428.54 | 4.02 | 4.02 |
| 358.39 | 1.28 | 1.28 |
| 439.40 | 4.67 | 4.67 |
| 381.44 | 2.60 | 2.60 |
| 368.48 | 4.23 | 4.23 |
| 359.50 | 2.28 | 2.28 |
| 277.78 | 4.02 | 4.02 |
| 474.01 | 4.09 | 4.09 |
| 328.32 | 3.18 | 3.18 |
| 436.47 | 3.58 | 3.58 |
| 485.43 | 5.70 | 5.70 |
| 449.38 | 5.11 | 5.11 |
| 493.40 | 4.47 | 4.47 |
| 388.49 | 2.29 | 2.29 |
| 334.80 | 2.57 | 2.57 |
| 290.39 | 2.49 | 2.49 |
| 258.32 | 2.85 | 2.85 |
| 536.60 | 2.69 | 2.69 |
| 438.33 | 3.31 | 3.31 |
| 428.54 | 4.02 | 4.02 |
| 339.85 | 3.74 | 3.74 |
| 390.44 | 3.88 | 3.88 |
| 320.41 | 2.73 | 2.73 |
| 331.40 | 1.99 | 1.99 |
| 434.52 | 4.82 | 4.82 |
| 348.49 | 3.88 | 3.88 |
| 513.59 | 5.30 | 5.30 |
| 360.40 | 3.16 | 3.16 |
| 313.39 | 2.85 | 2.85 |
| 453.52 | 5.00 | 5.00 |
| 332.36 | 2.44 | 2.44 |
| 451.55 | 4.37 | 4.37 |
| 358.44 | 2.60 | 2.60 |
| 285.34 | 3.33 | 3.33 |
| 298.39 | 3.79 | 3.79 |
| 362.44 | 3.24 | 3.24 |
| 395.44 | 4.18 | 4.18 |
| 457.66 | 7.59 | 7.59 |
| 449.58 | 3.47 | 3.47 |
| 313.36 | 1.88 | 1.88 |
| 343.45 | 3.01 | 3.01 |
| 355.40 | 2.35 | 2.35 |
| 494.43 | 4.44 | 4.44 |
| 399.50 | 3.32 | 3.32 |
| 406.92 | 1.91 | 1.91 |
| 372.45 | 3.80 | 3.80 |
| 486.56 | 3.56 | 3.56 |
| 388.38 | 2.92 | 2.92 |
| 431.38 | 5.14 | 5.14 |
| 443.55 | 3.72 | 3.72 |
| 340.39 | 2.65 | 2.65 |
| 441.55 | 3.82 | 3.82 |
| 460.97 | 3.18 | 3.18 |
| 338.34 | 2.32 | 2.32 |
| 329.40 | 2.10 | 2.10 |
| 344.48 | 3.37 | 3.37 |
| 381.39 | 4.30 | 4.30 |
| 325.46 | 2.52 | 2.52 |
| 411.55 | 4.26 | 4.26 |
| 475.55 | 3.08 | 3.08 |
| 490.99 | 5.25 | 5.25 |
| 378.47 | 4.69 | 4.69 |
| 363.46 | 2.68 | 2.68 |
| 339.29 | 3.69 | 3.69 |
| 311.18 | 2.31 | 2.31 |
| 477.65 | 2.91 | 2.91 |
| 428.54 | 4.02 | 4.02 |
| 212.25 | 3.21 | 3.21 |
| 330.45 | 3.13 | 3.13 |
| 381.18 | 3.63 | 3.63 |
| 353.40 | 3.02 | 3.02 |
| 466.57 | 1.86 | 1.86 |
| 425.49 | 3.56 | 3.56 |
| 342.38 | 1.42 | 1.42 |
| 342.44 | 2.96 | 2.96 |
| 390.51 | 4.74 | 4.74 |
| 473.46 | 2.70 | 2.70 |
| 436.49 | 4.40 | 4.40 |
| 325.37 | 2.89 | 2.89 |
| 433.49 | 3.63 | 3.63 |
| 270.29 | 2.34 | 2.34 |
| 455.56 | 3.14 | 3.14 |
| 428.54 | 4.02 | 4.02 |
| 394.27 | 2.56 | 2.56 |
| 356.38 | 3.37 | 3.37 |
| 435.34 | 5.67 | 5.67 |
| 394.48 | 1.87 | 1.87 |
| 476.56 | 3.24 | 3.24 |
| 306.30 | 3.06 | 3.06 |
| 307.39 | 4.54 | 4.54 |
| 353.38 | 2.51 | 2.51 |
| 469.57 | 6.27 | 6.27 |
| 330.43 | 2.86 | 2.86 |
| 768.76 | -2.05 | -2.05 |
| 316.41 | 3.93 | 3.93 |
| 425.95 | 5.00 | 5.00 |
| 345.86 | 4.19 | 4.19 |
| 401.51 | 3.78 | 3.78 |
| 255.15 | 2.67 | 2.67 |
| 376.31 | 3.74 | 3.74 |
| 365.42 | 0.46 | 0.46 |
| 457.29 | 3.15 | 3.15 |
| 336.44 | 4.32 | 4.32 |
| 448.49 | 6.21 | 6.21 |
| 417.94 | 4.36 | 4.36 |
| 404.54 | 2.37 | 2.37 |
| 351.41 | 2.41 | 2.41 |
| 360.44 | 2.28 | 2.28 |
| 326.35 | 3.74 | 3.74 |
| 343.24 | 3.53 | 3.53 |
| 397.53 | 3.87 | 3.87 |
| 425.51 | 2.69 | 2.69 |
| 456.45 | 3.83 | 3.83 |
| 385.42 | 3.76 | 3.76 |
| 444.96 | 4.47 | 4.47 |
| 302.40 | 3.41 | 3.41 |
| 301.39 | 3.05 | 3.05 |
| 328.41 | 2.76 | 2.76 |
| 414.42 | 4.71 | 4.71 |
| 392.36 | 4.06 | 4.06 |
| 398.87 | 5.37 | 5.37 |
| 329.21 | 2.13 | 2.13 |
| 464.98 | 2.10 | 2.10 |
| 346.45 | 3.56 | 3.56 |
| 472.54 | 3.63 | 3.63 |
| 367.33 | 2.32 | 2.32 |
| 366.51 | 3.37 | 3.37 |
| 267.25 | -0.01 | -0.01 |
| 363.35 | 2.10 | 2.10 |
| 372.41 | 1.77 | 1.77 |
| 277.71 | 2.57 | 2.57 |
| 330.45 | 3.72 | 3.72 |
| 465.55 | 3.54 | 3.54 |
| 555.72 | 5.45 | 5.45 |
| 325.32 | 1.86 | 1.86 |
| 413.52 | 5.87 | 5.87 |
| 425.51 | 2.61 | 2.61 |
| 494.43 | 4.44 | 4.44 |
| 340.39 | 4.04 | 4.04 |
| 397.53 | 4.01 | 4.01 |
| 412.54 | 4.32 | 4.32 |
| 455.54 | 5.88 | 5.88 |
| 360.40 | 3.38 | 3.38 |
| 373.42 | 3.29 | 3.29 |
| 401.51 | 3.91 | 3.91 |
| 512.25 | 5.29 | 5.29 |
| 392.41 | 4.57 | 4.57 |
| 256.31 | 2.29 | 2.29 |
| 467.79 | 5.18 | 5.18 |
| 327.38 | 2.27 | 2.27 |
| 267.74 | 3.75 | 3.75 |
| 380.40 | 2.81 | 2.81 |
| 413.36 | 4.56 | 4.56 |
| 378.28 | 5.75 | 5.75 |
| 528.87 | 5.09 | 5.09 |
| 381.48 | 3.80 | 3.80 |
| 314.38 | 2.37 | 2.37 |
| 471.56 | 2.84 | 2.84 |
| 260.29 | 2.08 | 2.08 |
| 388.56 | 4.04 | 4.04 |
| 359.81 | 3.75 | 3.75 |
| 359.41 | 1.98 | 1.98 |
| 467.61 | 6.59 | 6.59 |
| 353.38 | 3.92 | 3.92 |
| 326.35 | 3.26 | 3.26 |
| 370.21 | 3.02 | 3.02 |
| 414.41 | 3.88 | 3.88 |
| 438.48 | 3.62 | 3.62 |
| 408.46 | 3.61 | 3.61 |
| 252.73 | 3.66 | 3.66 |
| 394.39 | 2.91 | 2.91 |
| 316.38 | 4.48 | 4.48 |
| 353.41 | 3.37 | 3.37 |
| 331.44 | 3.40 | 3.40 |
| 449.59 | 6.78 | 6.78 |
| 388.49 | 2.48 | 2.48 |
| 376.41 | 3.50 | 3.50 |
| 260.30 | 3.25 | 3.25 |
| 272.30 | 1.88 | 1.88 |
| 408.89 | 4.51 | 4.51 |
| 423.47 | 3.73 | 3.73 |
| 352.42 | 3.62 | 3.62 |
| 350.51 | 4.13 | 4.13 |
| 282.39 | 3.67 | 3.67 |
| 459.98 | 3.78 | 3.78 |
| 414.51 | 3.63 | 3.63 |
| 262.26 | 2.15 | 2.15 |
| 283.33 | 4.11 | 4.11 |
| 405.45 | 5.79 | 5.79 |
| 259.33 | 3.48 | 3.48 |
| 387.69 | 3.64 | 3.64 |
| 400.44 | 4.11 | 4.11 |
| 453.58 | 6.28 | 6.28 |
| 287.36 | 2.71 | 2.71 |
| 368.26 | 3.41 | 3.41 |
| 319.19 | 4.72 | 4.72 |
| 437.45 | 3.62 | 3.62 |
| 364.38 | 3.68 | 3.68 |
| 380.40 | 3.48 | 3.48 |
| 383.75 | 4.69 | 4.69 |
| 301.39 | 3.10 | 3.10 |
| 331.40 | 2.32 | 2.32 |
| 430.08 | 4.03 | 4.03 |
| 330.39 | 1.82 | 1.82 |
| 373.41 | 3.20 | 3.20 |
| 446.64 | 4.16 | 4.16 |
| 480.50 | 3.86 | 3.86 |
| 438.50 | 3.45 | 3.45 |
| 353.45 | 2.76 | 2.76 |
| 344.42 | 2.21 | 2.21 |
| 340.40 | 3.93 | 3.93 |
| 280.27 | 2.39 | 2.39 |
| 341.43 | 4.43 | 4.43 |
| 466.63 | 6.34 | 6.34 |
| 421.57 | 2.90 | 2.90 |
| 215.30 | 2.96 | 2.96 |
| 410.42 | 4.08 | 4.08 |
| 279.30 | 3.24 | 3.24 |
| 343.43 | 2.83 | 2.83 |
| 405.57 | 3.06 | 3.06 |
| 340.81 | 3.87 | 3.87 |
| 375.43 | 4.91 | 4.91 |
| 385.86 | 3.25 | 3.25 |
| 411.48 | 3.21 | 3.21 |
| 436.52 | 1.13 | 1.13 |
| 450.47 | 4.78 | 4.78 |
| 285.34 | 4.20 | 4.20 |
| 352.40 | 1.53 | 1.53 |
| 328.37 | 2.35 | 2.35 |
| 237.26 | 3.04 | 3.04 |
| 415.52 | 5.62 | 5.62 |
| 413.43 | 3.73 | 3.73 |
| 294.35 | 3.91 | 3.91 |
| 409.46 | 4.91 | 4.91 |
| 387.83 | 2.83 | 2.83 |
| 338.46 | 5.31 | 5.31 |
| 344.44 | 5.12 | 5.12 |
| 333.23 | 2.38 | 2.38 |
| 349.43 | 2.93 | 2.93 |
| 417.94 | 4.36 | 4.36 |
| 361.45 | 3.46 | 3.46 |
| 343.24 | 3.53 | 3.53 |
| 444.54 | 4.28 | 4.28 |
| 529.64 | 1.87 | 1.87 |
| 386.41 | 3.98 | 3.98 |
| 420.51 | 3.31 | 3.31 |
| 248.28 | 2.27 | 2.27 |
| 561.73 | 3.55 | 3.55 |
| 477.52 | 4.25 | 4.25 |
| 390.46 | 3.36 | 3.36 |
| 368.46 | 4.55 | 4.55 |
| 310.38 | 3.72 | 3.72 |
| 487.56 | 3.50 | 3.50 |
| 310.28 | 2.28 | 2.28 |
| 382.42 | 3.06 | 3.06 |
| 437.49 | 3.98 | 3.98 |
| 385.47 | 4.55 | 4.55 |
| 471.92 | 2.87 | 2.87 |
| 447.54 | 4.37 | 4.37 |
| 362.28 | 3.35 | 3.35 |
| 349.44 | 3.39 | 3.39 |
| 336.44 | 4.32 | 4.32 |
| 290.34 | 3.35 | 3.35 |
| 474.65 | 4.23 | 4.23 |
| 357.45 | 3.26 | 3.26 |
| 302.33 | 2.53 | 2.53 |
| 407.54 | 2.51 | 2.51 |
| 288.33 | 2.83 | 2.83 |
| 387.49 | 4.24 | 4.24 |
| 289.59 | 3.32 | 3.32 |
| 344.46 | 3.47 | 3.47 |
| 387.43 | 2.73 | 2.73 |
| 466.54 | 5.11 | 5.11 |
| 260.30 | 1.47 | 1.47 |
| 475.57 | 4.14 | 4.14 |
| 354.41 | 3.97 | 3.97 |
| 362.39 | 1.97 | 1.97 |
| 342.85 | 1.25 | 1.25 |
| 450.52 | 4.79 | 4.79 |
| 358.46 | 3.24 | 3.24 |
| 391.45 | 3.93 | 3.93 |
| 394.47 | 5.10 | 5.10 |
| 273.34 | 2.45 | 2.45 |
| 262.26 | 2.15 | 2.15 |
| 488.04 | 4.76 | 4.76 |
| 386.47 | 4.19 | 4.19 |
| 465.59 | 6.48 | 6.48 |
| 442.61 | 3.80 | 3.80 |
| 407.54 | 4.78 | 4.78 |
| 460.63 | 3.84 | 3.84 |
| 394.43 | 4.35 | 4.35 |
| 437.58 | 6.58 | 6.58 |
| 421.01 | 4.00 | 4.00 |
| 354.88 | 4.03 | 4.03 |
| 373.24 | 4.24 | 4.24 |
| 343.32 | 3.44 | 3.44 |
| 345.51 | 3.82 | 3.82 |
| 314.34 | 2.70 | 2.70 |
| 425.47 | 2.92 | 2.92 |
| 414.51 | 3.63 | 3.63 |
| 338.36 | 3.82 | 3.82 |
| 432.27 | 4.26 | 4.26 |
| 342.44 | 3.19 | 3.19 |
| 354.43 | 4.24 | 4.24 |
| 464.57 | 1.83 | 1.83 |
| 346.43 | 3.22 | 3.22 |
| 368.35 | 2.76 | 2.76 |
| 475.55 | 4.99 | 4.99 |
| 397.53 | 4.01 | 4.01 |
| 326.47 | 2.64 | 2.64 |
| 336.84 | 2.91 | 2.91 |
| 380.49 | 2.93 | 2.93 |
| 194.62 | 2.48 | 2.48 |
| 374.42 | 3.47 | 3.47 |
| 350.41 | 2.41 | 2.41 |
| 353.40 | 1.23 | 1.23 |
| 351.41 | 3.04 | 3.04 |
| 421.93 | 4.26 | 4.26 |
| 536.65 | 4.09 | 4.09 |
| 366.46 | 3.60 | 3.60 |
| 254.34 | 4.06 | 4.06 |
| 428.43 | 3.55 | 3.55 |
| 494.56 | 2.92 | 2.92 |
| 301.34 | 2.38 | 2.38 |
| 420.54 | 3.09 | 3.09 |
| 361.49 | 3.31 | 3.31 |
| 470.50 | 3.86 | 3.86 |
| 395.27 | 3.32 | 3.32 |
| 508.62 | 2.92 | 2.92 |
| 426.52 | 2.44 | 2.44 |
| 483.62 | 3.71 | 3.71 |
| 497.60 | 3.78 | 3.78 |
| 369.47 | 4.08 | 4.08 |
| 458.51 | 2.82 | 2.82 |
| 446.45 | 3.96 | 3.96 |
| 434.51 | 4.87 | 4.87 |
| 398.46 | 2.08 | 2.08 |
| 462.53 | 3.81 | 3.81 |
| 235.31 | 1.60 | 1.60 |
| 476.60 | 2.95 | 2.95 |
| 383.48 | 2.10 | 2.10 |
| 319.39 | 2.51 | 2.51 |
| 444.56 | 1.76 | 1.76 |
| 447.58 | 4.28 | 4.28 |
| 563.74 | 3.81 | 3.81 |
| 381.43 | 3.27 | 3.27 |
| 374.23 | 5.08 | 5.08 |
| 572.68 | 4.76 | 4.76 |
| 518.69 | 2.72 | 2.72 |
| 654.95 | 6.57 | 6.57 |
| 358.39 | 3.48 | 3.48 |
| 371.48 | 2.16 | 2.16 |
| 317.37 | 1.68 | 1.68 |
| 482.95 | 3.83 | 3.83 |
| 485.50 | 3.71 | 3.71 |
| 362.86 | 4.80 | 4.80 |
| 383.28 | 5.14 | 5.14 |
| 578.00 | 4.98 | 4.98 |
| 280.36 | 1.96 | 1.96 |
| 523.57 | 1.80 | 1.80 |
| 397.44 | 3.81 | 3.81 |
| 283.35 | 1.27 | 1.27 |
| 330.41 | 4.46 | 4.46 |
| 311.43 | 2.00 | 2.00 |
| 240.72 | 1.91 | 1.91 |
| 452.54 | 3.43 | 3.43 |
| 529.56 | 4.11 | 4.11 |
| 371.48 | 5.11 | 5.11 |
| 382.43 | 4.20 | 4.20 |
| 431.50 | 2.99 | 2.99 |
| 485.62 | 4.95 | 4.95 |
| 280.36 | 1.96 | 1.96 |
| 428.50 | 3.69 | 3.69 |
| 291.35 | 3.37 | 3.37 |
| 433.58 | 5.01 | 5.01 |
| 433.47 | 2.93 | 2.93 |
| 414.47 | 3.38 | 3.38 |
| 404.47 | 3.96 | 3.96 |
| 429.52 | 4.42 | 4.42 |
| 479.50 | 1.80 | 1.80 |
| 318.20 | 1.63 | 1.63 |
| 395.49 | 3.35 | 3.35 |
| 378.46 | 3.66 | 3.66 |
| 515.53 | 3.72 | 3.72 |
| 387.45 | 2.97 | 2.97 |
| 403.48 | 3.31 | 3.31 |
| 382.49 | 3.69 | 3.69 |
| 332.37 | 3.22 | 3.22 |
| 444.61 | 5.03 | 5.03 |
| 405.53 | 4.23 | 4.23 |
| 361.19 | 2.73 | 2.73 |
| 285.26 | -1.63 | -1.63 |