Basic Information
ID: ALA1738164
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493098, AID493121, AID493159]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1738164
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 327.34 | 2.30 | 2.30 |
| 453.29 | 3.36 | 3.36 |
| 214.29 | 2.87 | 2.87 |
| 356.18 | 5.18 | 5.18 |
| 328.17 | 3.67 | 3.67 |
| 317.33 | 2.31 | 2.31 |
| 179.61 | 2.59 | 2.59 |
| 97.07 | -0.80 | -0.80 |
| 391.93 | 5.33 | 5.33 |
| 305.39 | 4.08 | 4.08 |
| 424.51 | 3.42 | 3.42 |
| 302.28 | 1.72 | 1.72 |
| 572.57 | 4.11 | 4.11 |
| 335.77 | 3.71 | 3.71 |
| 341.75 | 3.47 | 3.47 |
| 336.44 | 4.32 | 4.32 |
| 461.61 | 3.45 | 3.45 |
| 471.86 | 6.57 | 6.57 |
| 382.42 | 3.61 | 3.61 |
| 351.36 | 3.38 | 3.38 |
| 317.44 | 3.45 | 3.45 |
| 512.20 | 4.89 | 4.89 |
| 436.77 | 6.31 | 6.31 |
| 477.63 | 4.69 | 4.69 |
| 379.42 | 4.02 | 4.02 |
| 445.61 | 3.90 | 3.90 |
| 236.20 | 3.86 | 3.86 |
| 571.58 | 3.15 | 3.15 |
| 219.27 | 3.57 | 3.57 |
| 451.60 | 3.49 | 3.49 |
| 317.26 | 2.70 | 2.70 |
| 317.44 | 3.45 | 3.45 |
| 190.16 | 1.85 | 1.85 |
| 397.82 | 3.25 | 3.25 |
| 394.39 | 2.93 | 2.93 |
| 313.29 | 3.14 | 3.14 |
| 352.44 | 3.34 | 3.34 |
| 397.43 | 1.85 | 1.85 |
| 336.46 | 4.04 | 4.04 |
| 278.31 | 2.77 | 2.77 |
| 357.70 | 4.49 | 4.49 |
| 291.31 | 3.87 | 3.87 |
| 449.36 | 3.08 | 3.08 |
| 395.55 | 5.47 | 5.47 |
| 377.42 | 2.97 | 2.97 |
| 329.38 | 2.96 | 2.96 |
| 277.28 | 2.35 | 2.35 |
| 448.49 | 5.59 | 5.59 |
| 329.23 | 4.92 | 4.92 |
| 386.86 | 4.74 | 4.74 |
| 354.79 | 3.82 | 3.82 |
| 335.34 | 2.48 | 2.48 |
| 354.48 | 1.16 | 1.16 |
| 378.50 | 4.08 | 4.08 |
| 395.89 | 4.60 | 4.60 |
| 439.58 | 5.22 | 5.22 |
| 382.41 | 4.62 | 4.62 |
| 443.55 | 2.99 | 2.99 |
| 267.67 | 1.79 | 1.79 |
| 391.43 | 2.51 | 2.51 |
| 354.48 | 1.50 | 1.50 |
| 325.39 | 3.61 | 3.61 |
| 289.34 | 3.31 | 3.31 |
| 252.21 | 2.02 | 2.02 |
| 340.45 | 0.77 | 0.77 |
| 279.32 | 1.97 | 1.97 |
| 381.41 | 3.17 | 3.17 |
| 370.43 | 3.32 | 3.32 |
| 437.68 | 3.32 | 3.32 |
| 448.49 | 5.59 | 5.59 |
| 546.45 | 6.51 | 6.51 |
| 391.45 | 2.73 | 2.73 |
| 341.22 | 3.83 | 3.83 |
| 476.00 | 3.68 | 3.68 |
| 319.41 | 4.02 | 4.02 |
| 400.89 | 5.05 | 5.05 |
| 306.32 | 2.30 | 2.30 |
| 259.29 | 1.42 | 1.42 |
| 319.67 | 2.09 | 2.09 |
| 273.68 | 3.70 | 3.70 |
| 474.20 | 3.60 | 3.60 |
| 325.58 | 3.13 | 3.13 |
| 278.29 | 2.13 | 2.13 |
| 310.31 | 2.40 | 2.40 |
| 313.38 | 1.94 | 1.94 |
| 332.26 | 2.84 | 2.84 |
| 263.35 | 1.83 | 1.83 |
| 334.76 | 1.18 | 1.18 |
| 319.14 | 1.09 | 1.09 |
| 355.44 | 3.81 | 3.81 |
| 356.38 | 3.66 | 3.66 |
| 354.79 | 3.64 | 3.64 |
| 340.77 | 3.33 | 3.33 |
| 297.22 | 1.64 | 1.64 |
| 342.74 | 4.32 | 4.32 |
| 385.84 | 2.74 | 2.74 |
| 426.34 | 3.99 | 3.99 |
| 300.39 | 3.43 | 3.43 |
| 425.62 | 4.08 | 4.08 |
| 302.29 | 3.82 | 3.82 |
| 382.41 | 4.62 | 4.62 |
| 277.37 | 2.13 | 2.13 |
| 346.35 | 3.99 | 3.99 |
| 384.40 | -1.24 | -1.24 |
| 317.50 | 4.65 | 4.65 |
| 426.37 | 4.17 | 4.17 |
| 284.70 | 3.50 | 3.50 |
| 363.85 | 4.67 | 4.67 |
| 323.83 | 3.40 | 3.40 |
| 419.87 | 3.80 | 3.80 |
| 514.52 | 3.95 | 3.95 |
| 344.93 | 5.06 | 5.06 |
| 468.46 | 3.46 | 3.46 |
| 350.37 | 3.18 | 3.18 |
| 484.49 | 3.94 | 3.94 |
| 379.45 | 2.70 | 2.70 |
| 537.39 | 4.22 | 4.22 |
| 545.27 | 4.26 | 4.26 |
| 332.38 | 2.91 | 2.91 |
| 526.53 | 4.11 | 4.11 |
| 434.63 | 4.16 | 4.16 |
| 317.50 | 4.45 | 4.45 |
| 384.39 | 4.77 | 4.77 |
| 465.77 | 5.94 | 5.94 |
| 352.35 | 2.39 | 2.39 |
| 310.23 | 2.11 | 2.11 |
| 339.42 | 3.79 | 3.79 |
| 410.91 | 3.15 | 3.15 |
| 445.48 | 3.26 | 3.26 |
| 399.49 | 6.05 | 6.05 |
| 326.42 | 0.68 | 0.68 |
| 462.37 | 3.01 | 3.01 |
| 264.28 | 2.47 | 2.47 |
| 476.71 | 5.68 | 5.68 |
| 373.21 | 2.32 | 2.32 |
| 357.46 | 4.84 | 4.84 |
| 422.53 | 4.46 | 4.46 |
| 417.47 | 2.81 | 2.81 |
| 444.40 | 2.54 | 2.54 |
| 264.24 | 1.65 | 1.65 |
| 323.74 | 3.50 | 3.50 |
| 354.41 | 3.73 | 3.73 |
| 333.30 | 2.94 | 2.94 |
| 376.41 | 1.58 | 1.58 |
| 385.94 | 4.71 | 4.71 |
| 372.28 | 2.86 | 2.86 |
| 386.46 | 3.76 | 3.76 |
| 246.26 | 2.79 | 2.79 |
| 308.12 | 4.35 | 4.35 |
| 391.47 | 2.15 | 2.15 |
| 357.44 | 2.60 | 2.60 |
| 583.39 | 5.15 | 5.15 |
| 339.45 | 4.78 | 4.78 |
| 349.35 | 4.80 | 4.80 |
| 353.45 | 4.15 | 4.15 |
| 314.41 | 3.52 | 3.52 |
| 432.25 | 5.57 | 5.57 |
| 310.38 | 3.47 | 3.47 |
| 311.30 | 2.97 | 2.97 |
| 375.29 | 3.92 | 3.92 |
| 444.46 | 3.51 | 3.51 |
| 381.50 | 3.91 | 3.91 |
| 323.83 | 3.40 | 3.40 |
| 355.46 | 3.94 | 3.94 |
| 395.44 | 2.49 | 2.49 |
| 299.72 | 3.64 | 3.64 |
| 510.43 | 4.86 | 4.86 |
| 358.42 | 3.37 | 3.37 |
| 373.44 | 3.57 | 3.57 |
| 381.48 | 3.46 | 3.46 |
| 358.37 | 5.40 | 5.40 |
| 415.23 | 2.90 | 2.90 |
| 239.18 | 1.72 | 1.72 |
| 287.70 | 3.92 | 3.92 |
| 256.30 | 2.11 | 2.11 |
| 307.38 | 2.89 | 2.89 |
| 319.36 | 3.87 | 3.87 |
| 246.22 | 1.64 | 1.64 |
| 313.74 | 3.95 | 3.95 |
| 379.40 | 4.76 | 4.76 |
| 367.39 | 2.87 | 2.87 |
| 582.48 | 2.89 | 2.89 |
| 409.42 | 2.99 | 2.99 |
| 243.26 | 3.49 | 3.49 |
| 338.33 | 3.31 | 3.31 |
| 359.22 | 3.97 | 3.97 |
| 365.41 | 3.47 | 3.47 |
| 319.28 | 2.94 | 2.94 |
| 322.15 | 4.57 | 4.57 |
| 341.39 | 2.65 | 2.65 |
| 450.56 | 4.55 | 4.55 |
| 254.29 | 3.70 | 3.70 |
| 478.46 | 6.02 | 6.02 |
| 428.44 | 5.55 | 5.55 |
| 650.86 | 7.40 | 7.40 |
| 387.48 | 2.15 | 2.15 |
| 337.85 | 2.39 | 2.39 |
| 396.42 | 3.16 | 3.16 |
| 558.45 | -1.80 | -1.80 |
| 308.30 | 3.29 | 3.29 |
| 390.34 | 2.45 | 2.45 |
| 293.32 | 3.78 | 3.78 |
| 306.23 | 1.00 | 1.00 |
| 508.60 | 2.07 | 2.07 |
| 237.26 | 2.57 | 2.57 |
| 470.69 | 5.66 | 5.66 |
| 450.62 | 6.70 | 6.70 |
| 245.79 | 2.64 | 2.64 |
| 452.51 | 3.82 | 3.82 |
| 268.07 | 1.71 | 1.71 |
| 351.20 | 3.43 | 3.43 |
| 461.49 | 4.59 | 4.59 |
| 309.34 | 3.82 | 3.82 |
| 277.33 | 3.78 | 3.78 |
| 277.28 | 2.38 | 2.38 |
| 541.74 | 6.74 | 6.74 |
| 277.19 | 1.24 | 1.24 |
| 714.68 | 2.70 | 2.70 |
| 311.77 | 3.35 | 3.35 |
| 295.81 | 2.62 | 2.62 |
| 456.42 | 4.20 | 4.20 |
| 468.51 | 5.44 | 5.44 |
| 458.04 | 5.09 | 5.09 |
| 201.22 | 1.73 | 1.73 |
| 454.57 | 4.92 | 4.92 |
| 367.87 | 2.90 | 2.90 |
| 326.37 | 3.47 | 3.47 |
| 387.28 | 5.99 | 5.99 |
| 311.29 | 3.42 | 3.42 |
| 258.24 | 2.14 | 2.14 |
| 426.00 | 4.67 | 4.67 |
| 305.76 | 2.63 | 2.63 |
| 278.29 | 3.30 | 3.30 |
| 291.14 | 4.14 | 4.14 |
| 434.36 | 4.87 | 4.87 |
| 339.40 | 2.67 | 2.67 |
| 304.37 | 3.81 | 3.81 |
| 319.37 | 2.63 | 2.63 |
| 366.32 | 4.42 | 4.42 |
| 438.51 | 3.07 | 3.07 |
| 410.48 | 3.16 | 3.16 |
| 460.51 | 4.37 | 4.37 |
| 279.45 | 3.19 | 3.19 |
| 432.50 | 4.32 | 4.32 |
| 324.36 | 3.17 | 3.17 |
| 320.40 | 3.29 | 3.29 |
| 258.24 | 2.14 | 2.14 |
| 313.38 | 3.13 | 3.13 |
| 273.25 | 2.45 | 2.45 |
| 410.48 | 3.82 | 3.82 |
| 301.26 | 3.00 | 3.00 |
| 394.48 | 4.12 | 4.12 |
| 302.77 | 2.74 | 2.74 |
| 410.43 | 3.57 | 3.57 |
| 321.53 | 4.53 | 4.53 |
| 292.68 | 2.79 | 2.79 |
| 424.30 | 4.50 | 4.50 |
| 354.39 | 3.59 | 3.59 |
| 300.27 | 2.46 | 2.46 |
| 268.34 | 3.62 | 3.62 |
| 434.47 | 3.77 | 3.77 |
| 422.53 | 4.74 | 4.74 |
| 249.19 | 0.26 | 0.26 |
| 343.39 | 3.36 | 3.36 |
| 367.39 | 2.97 | 2.97 |
| 311.43 | 4.27 | 4.27 |
| 339.78 | 3.42 | 3.42 |
| 295.43 | 1.99 | 1.99 |
| 332.75 | 4.15 | 4.15 |
| 319.36 | 3.40 | 3.40 |
| 408.50 | 4.43 | 4.43 |
| 422.44 | 3.77 | 3.77 |
| 417.47 | 4.48 | 4.48 |
| 474.54 | 4.68 | 4.68 |
| 430.47 | 3.58 | 3.58 |
| 490.49 | 3.54 | 3.54 |
| 453.06 | 4.80 | 4.80 |
| 386.48 | 2.02 | 2.02 |
| 359.21 | 2.63 | 2.63 |
| 343.22 | 4.27 | 4.27 |
| 450.46 | 3.28 | 3.28 |
| 460.74 | 6.50 | 6.50 |