Basic Information
ID: ALA1738171
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485273, AID485343]
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA1738171
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 403.98 | 3.94 | 3.94 |
| 505.46 | 4.18 | 4.18 |
| 299.50 | 3.92 | 3.92 |
| 337.81 | 4.43 | 4.43 |
| 510.06 | 6.08 | 6.08 |
| 289.34 | 0.64 | 0.64 |
| 243.29 | 2.36 | 2.36 |
| 576.69 | 7.25 | 7.25 |
| 580.54 | -1.17 | -1.17 |
| 301.52 | 4.15 | 4.15 |
| 614.56 | 7.32 | 7.32 |
| 467.57 | 4.62 | 4.62 |
| 525.07 | 5.35 | 5.35 |
| 462.52 | 6.52 | 6.52 |
| 337.21 | 3.39 | 3.39 |
| 473.99 | 4.31 | 4.31 |
| 406.46 | 2.13 | 2.13 |
| 591.72 | 8.05 | 8.05 |
| 687.71 | 10.29 | 10.29 |
| 238.81 | -0.36 | -0.36 |
| 427.35 | 4.38 | 4.38 |
| 545.08 | 4.67 | 4.67 |
| 359.39 | 1.61 | 1.61 |
| 551.63 | 2.59 | 2.59 |
| 443.58 | 4.80 | 4.80 |
| 277.30 | 4.14 | 4.14 |
| 514.61 | 5.39 | 5.39 |
| 422.49 | 2.03 | 2.03 |
| 631.22 | 4.66 | 4.66 |
| 599.22 | 5.26 | 5.26 |
| 344.46 | 5.09 | 5.09 |
| 461.61 | 3.02 | 3.02 |
| 503.47 | 4.33 | 4.33 |
| 459.57 | 2.71 | 2.71 |
| 462.12 | 6.38 | 6.38 |
| 448.55 | 4.83 | 4.83 |
| 524.67 | 4.16 | 4.16 |
| 705.22 | 2.53 | 2.53 |
| 349.37 | 3.33 | 3.33 |
| 482.63 | 3.58 | 3.58 |
| 503.08 | 5.74 | 5.74 |
| 315.38 | 4.76 | 4.76 |
| 465.53 | 3.09 | 3.09 |
| 260.34 | 4.24 | 4.24 |
| 337.38 | 2.88 | 2.88 |
| 509.61 | 3.65 | 3.65 |
| 396.86 | 1.62 | 1.62 |
| 490.59 | 5.01 | 5.01 |
| 442.93 | 4.20 | 4.20 |
| 451.96 | 3.47 | 3.47 |
| 538.04 | 2.70 | 2.70 |
| 424.52 | 0.48 | 0.48 |
| 438.67 | 6.28 | 6.28 |
| 417.49 | 4.27 | 4.27 |
| 321.40 | 1.11 | 1.11 |
| 316.18 | 1.10 | 1.10 |
| 323.37 | 0.51 | 0.51 |
| 422.65 | 2.72 | 2.72 |
| 351.28 | 3.08 | 3.08 |
| 438.96 | 4.37 | 4.37 |
| 528.63 | 3.91 | 3.91 |
| 276.37 | 4.04 | 4.04 |
| 421.43 | 5.24 | 5.24 |
| 468.51 | 3.65 | 3.65 |
| 320.40 | 2.75 | 2.75 |
| 303.36 | 3.58 | 3.58 |
| 488.41 | 3.35 | 3.35 |
| 531.05 | 4.74 | 4.74 |
| 446.51 | 3.28 | 3.28 |
| 532.63 | 3.30 | 3.30 |
| 344.33 | 5.52 | 5.52 |
| 481.58 | 3.48 | 3.48 |
| 366.35 | 1.75 | 1.75 |
| 267.31 | 0.44 | 0.44 |
| 441.55 | 3.97 | 3.97 |
| 603.21 | 5.11 | 5.11 |
| 640.75 | 6.38 | 6.38 |
| 475.57 | 2.33 | 2.33 |
| 423.24 | 4.26 | 4.26 |
| 384.51 | 4.02 | 4.02 |
| 595.19 | 4.23 | 4.23 |
| 579.23 | 5.46 | 5.46 |
| 486.55 | 2.61 | 2.61 |
| 513.58 | 2.88 | 2.88 |
| 334.46 | 5.04 | 5.04 |
| 334.43 | 2.03 | 2.03 |
| 437.45 | 2.83 | 2.83 |
| 488.05 | 4.35 | 4.35 |
| 304.38 | 3.42 | 3.42 |
| 501.45 | 4.09 | 4.09 |
| 456.40 | 4.33 | 4.33 |
| 370.43 | 1.98 | 1.98 |
| 335.43 | 3.65 | 3.65 |
| 439.58 | 1.77 | 1.77 |
| 321.38 | 4.52 | 4.52 |
| 312.35 | 4.06 | 4.06 |
| 299.35 | 3.00 | 3.00 |
| 539.57 | -0.61 | -0.61 |
| 396.43 | 3.08 | 3.08 |
| 448.49 | 6.21 | 6.21 |
| 277.30 | 4.14 | 4.14 |
| 386.77 | 2.10 | 2.10 |
| 506.63 | 5.30 | 5.30 |
| 444.90 | 3.31 | 3.31 |
| 593.38 | 5.51 | 5.51 |
| 409.96 | 2.71 | 2.71 |
| 562.65 | 3.39 | 3.39 |
| 461.57 | 3.01 | 3.01 |
| 390.43 | 2.89 | 2.89 |
| 399.52 | 1.96 | 1.96 |
| 420.47 | 3.65 | 3.65 |
| 447.41 | 2.65 | 2.65 |
| 295.35 | 1.43 | 1.43 |
| 290.39 | 4.39 | 4.39 |
| 498.63 | 3.33 | 3.33 |
| 480.03 | 3.45 | 3.45 |
| 601.19 | 4.65 | 4.65 |
| 399.56 | 4.09 | 4.09 |
| 542.66 | 4.30 | 4.30 |
| 486.96 | 3.54 | 3.54 |
| 246.26 | 2.71 | 2.71 |
| 437.55 | 4.25 | 4.25 |
| 538.07 | 4.90 | 4.90 |
| 272.33 | 1.24 | 1.24 |
| 345.43 | 4.47 | 4.47 |
| 484.60 | 3.31 | 3.31 |
| 466.47 | 5.94 | 5.94 |
| 455.30 | 3.54 | 3.54 |
| 536.12 | 4.45 | 4.45 |
| 585.20 | 4.95 | 4.95 |
| 441.53 | 3.52 | 3.52 |
| 482.61 | 3.88 | 3.88 |
| 529.62 | 5.01 | 5.01 |
| 403.39 | 0.12 | 0.12 |
| 323.33 | 2.80 | 2.80 |
| 358.42 | 3.61 | 3.61 |
| 282.76 | 2.91 | 2.91 |
| 321.40 | 1.11 | 1.11 |
| 581.72 | 3.98 | 3.98 |
| 464.62 | 4.15 | 4.15 |
| 603.17 | 4.44 | 4.44 |
| 445.74 | 3.20 | 3.20 |
| 339.42 | 2.93 | 2.93 |
| 459.55 | 2.59 | 2.59 |
| 545.27 | 4.26 | 4.26 |
| 391.42 | 4.33 | 4.33 |
| 451.96 | 3.47 | 3.47 |
| 432.36 | 4.33 | 4.33 |
| 469.57 | 3.28 | 3.28 |
| 531.63 | 3.77 | 3.77 |
| 465.33 | 2.37 | 2.37 |
| 454.55 | 2.69 | 2.69 |
| 539.03 | 3.45 | 3.45 |
| 450.95 | 5.43 | 5.43 |
| 615.22 | 5.04 | 5.04 |
| 547.50 | 4.40 | 4.40 |
| 304.74 | 1.14 | 1.14 |
| 304.42 | 4.77 | 4.77 |
| 406.87 | 4.61 | 4.61 |
| 317.35 | 2.60 | 2.60 |
| 642.68 | 6.29 | 6.29 |
| 508.09 | 5.69 | 5.69 |
| 288.31 | 3.03 | 3.03 |
| 507.50 | 6.38 | 6.38 |
| 306.39 | 3.51 | 3.51 |
| 397.53 | 1.54 | 1.54 |
| 558.53 | 4.97 | 4.97 |
| 483.59 | 3.66 | 3.66 |
| 631.22 | 4.66 | 4.66 |
| 465.69 | 5.31 | 5.31 |
| 397.52 | 3.13 | 3.13 |
| 417.47 | 2.81 | 2.81 |
| 296.33 | 2.52 | 2.52 |
| 458.93 | 3.62 | 3.62 |
| 364.41 | 3.51 | 3.51 |
| 341.38 | 3.33 | 3.33 |
| 332.43 | 4.04 | 4.04 |
| 309.39 | 1.52 | 1.52 |
| 536.12 | 4.45 | 4.45 |
| 421.48 | 4.11 | 4.11 |
| 503.08 | 5.74 | 5.74 |
| 473.56 | 2.08 | 2.08 |
| 245.28 | 2.23 | 2.23 |
| 403.56 | 4.76 | 4.76 |
| 387.44 | 2.42 | 2.42 |
| 415.47 | 2.41 | 2.41 |
| 317.35 | 4.15 | 4.15 |
| 396.47 | 3.77 | 3.77 |
| 406.47 | 4.41 | 4.41 |
| 497.52 | 2.80 | 2.80 |
| 351.43 | 1.26 | 1.26 |
| 415.71 | 2.74 | 2.74 |
| 383.43 | 2.85 | 2.85 |
| 377.45 | 3.34 | 3.34 |
| 381.26 | 3.93 | 3.93 |
| 1001.73 | 1.28 | 1.28 |
| 476.60 | 5.29 | 5.29 |
| 524.06 | 3.11 | 3.11 |
| 296.37 | 1.92 | 1.92 |
| 413.59 | 3.59 | 3.59 |
| 376.89 | 4.85 | 4.85 |
| 551.08 | 9.23 | 9.23 |
| 342.36 | 0.79 | 0.79 |
| 516.69 | 3.10 | 3.10 |
| 615.22 | 5.04 | 5.04 |
| 496.96 | 2.16 | 2.16 |
| 597.72 | 3.76 | 3.76 |
| 418.50 | 3.09 | 3.09 |
| 483.71 | 3.76 | 3.76 |
| 478.57 | 1.93 | 1.93 |
| 310.38 | 4.66 | 4.66 |
| 496.01 | 2.10 | 2.10 |
| 331.76 | 1.81 | 1.81 |
| 544.48 | 3.28 | 3.28 |
| 336.38 | 3.91 | 3.91 |
| 601.19 | 4.65 | 4.65 |
| 538.09 | 3.58 | 3.58 |
| 411.51 | 3.51 | 3.51 |
| 504.81 | 5.69 | 5.69 |
| 536.07 | 3.22 | 3.22 |
| 352.42 | 2.62 | 2.62 |
| 335.43 | 1.62 | 1.62 |
| 359.84 | 3.71 | 3.71 |
| 571.24 | 5.01 | 5.01 |
| 616.05 | 5.22 | 5.22 |
| 480.68 | 4.11 | 4.11 |
| 607.63 | 5.41 | 5.41 |
| 537.05 | 8.84 | 8.84 |
| 631.22 | 4.88 | 4.88 |
| 408.41 | 1.39 | 1.39 |
| 587.21 | 5.33 | 5.33 |
| 463.46 | 3.29 | 3.29 |
| 814.84 | 5.62 | 5.62 |
| 370.43 | 3.82 | 3.82 |
| 467.55 | 3.17 | 3.17 |
| 386.77 | 2.10 | 2.10 |
| 363.83 | 1.72 | 1.72 |
| 534.68 | 3.24 | 3.24 |
| 360.44 | 2.65 | 2.65 |
| 384.45 | 3.76 | 3.76 |
| 352.38 | 3.39 | 3.39 |
| 474.54 | 3.20 | 3.20 |
| 451.96 | 3.64 | 3.64 |
| 567.13 | 3.80 | 3.80 |
| 339.18 | 1.79 | 1.79 |
| 599.22 | 5.20 | 5.20 |
| 406.48 | 3.65 | 3.65 |
| 420.32 | 2.47 | 2.47 |
| 465.62 | 4.18 | 4.18 |
| 317.86 | 3.53 | 3.53 |
| 925.11 | -1.49 | -1.49 |
| 483.55 | 2.87 | 2.87 |
| 349.43 | 3.78 | 3.78 |
| 309.33 | 2.10 | 2.10 |
| 361.79 | 1.30 | 1.30 |
| 898.09 | -1.91 | -1.91 |
| 445.58 | 5.95 | 5.95 |
| 511.62 | 4.51 | 4.51 |
| 937.17 | -1.38 | -1.38 |
| 393.51 | 1.03 | 1.03 |
| 966.21 | -0.89 | -0.89 |
| 909.16 | -0.31 | -0.31 |
| 421.43 | 5.24 | 5.24 |
| 419.92 | -0.03 | -0.03 |
| 446.00 | 2.02 | 2.02 |
| 387.37 | 4.02 | 4.02 |
| 1001.73 | 1.28 | 1.28 |
| 425.58 | 2.32 | 2.32 |
| 981.23 | -1.46 | -1.46 |
| 392.51 | 4.11 | 4.11 |
| 644.78 | -1.13 | -1.13 |
| 461.58 | 2.65 | 2.65 |
| 897.10 | -1.97 | -1.97 |
| 967.15 | -3.06 | -3.06 |
| 577.91 | 5.80 | 5.80 |
| 853.05 | -1.90 | -1.90 |
| 532.49 | 4.77 | 4.77 |
| 381.45 | 0.93 | 0.93 |
| 318.36 | 0.37 | 0.37 |
| 487.60 | 3.34 | 3.34 |
| 993.28 | 0.20 | 0.20 |
| 471.55 | 3.67 | 3.67 |
| 502.61 | 3.15 | 3.15 |
| 1246.66 | ||
| 1218.65 | ||
| 351.41 | 4.02 | 4.02 |
| 1222.66 | ||
| 329.45 | 3.77 | 3.77 |
| 1306.78 | ||
| 1306.78 | ||
| 1162.54 | ||
| 1306.78 | ||
| 1329.84 | ||
| 1306.78 | ||
| 1222.66 | ||
| 392.42 | 3.97 | 3.97 |
| 1275.74 | ||
| 1162.54 | ||
| 1317.78 | ||
| 374.44 | 3.66 | 3.66 |
| 358.38 | 3.72 | 3.72 |
| 396.43 | 0.58 | 0.58 |
| 302.40 | 4.54 | 4.54 |
| 300.39 | 4.45 | 4.45 |
| 330.41 | 4.46 | 4.46 |
| 302.77 | 2.74 | 2.74 |
| 320.37 | 1.81 | 1.81 |
| 320.37 | 1.81 | 1.81 |
| 419.46 | 3.00 | 3.00 |
| 350.40 | 1.82 | 1.82 |
| 299.36 | 2.28 | 2.28 |
| 343.41 | 3.37 | 3.37 |
| 309.34 | 4.14 | 4.14 |
| 261.31 | 1.19 | 1.19 |
| 330.37 | 2.37 | 2.37 |
| 347.42 | 2.83 | 2.83 |
| 464.47 | 4.62 | 4.62 |
| 250.30 | 2.02 | 2.02 |
| 350.38 | 3.14 | 3.14 |
| 739.66 | 5.72 | 5.72 |
| 332.79 | 2.53 | 2.53 |
| 330.37 | 2.37 | 2.37 |
| 420.64 | 3.76 | 3.76 |