Assay Report Card

Basic Information

ID: ALA1738173

Type: Functional

Description: PUBCHEM_BIOASSAY: Inhibitors of T. brucei phosphofructokinase: Hit Validation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488768]

Organism: Trypanosoma brucei TREU927

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
270.242.582.58
211.220.440.44
267.332.852.85
167.200.600.60
464.38-0.54-0.54
286.242.282.28
227.293.053.05
151.191.591.59
290.413.793.79
318.241.691.69
360.321.761.76
220.181.021.02
248.383.653.65
398.423.483.48
287.102.772.77
434.430.220.22
274.232.072.07
305.771.841.84
276.773.383.38
437.934.204.20
481.605.295.29
448.38-0.24-0.24
310.401.731.73
337.423.153.15
453.46-0.54-0.54
186.211.341.34
270.242.422.42
624.59-1.02-1.02
288.393.313.31
360.322.602.60
290.261.921.92
292.173.973.97
260.131.301.30
374.283.413.41
367.925.325.32
278.262.852.85
191.251.961.96
610.737.857.85
243.292.152.15
297.313.053.05
375.343.943.94
220.323.283.28
260.130.910.91
328.232.392.39
350.262.722.72
321.802.852.85
301.733.233.23
266.402.912.91
220.222.972.97
345.453.823.82
206.252.392.39
355.872.892.89
217.321.241.24
359.844.044.04
239.702.092.09
365.216.046.04
422.492.282.28
416.502.632.63
432.482.042.04
488.503.783.78
230.271.541.54
283.113.143.14
400.783.333.33
365.393.163.16
420.743.783.78
257.313.303.30
401.323.293.29
363.423.353.35
334.472.242.24
396.451.271.27
365.892.972.97
236.132.562.56
368.931.671.67
288.373.773.77
191.213.033.03
334.351.111.11
306.673.233.23
460.585.585.58
339.873.763.76
244.243.363.36
230.341.651.65
259.313.503.50
514.615.395.39
344.131.801.80
420.303.903.90
320.223.543.54
242.232.712.71
299.113.883.88
282.262.692.69
249.293.093.09
360.344.984.98
455.523.923.92
401.441.601.60
480.932.402.40
275.303.203.20
334.253.933.93
372.453.133.13
470.531.381.38
426.452.982.98
394.213.303.30
435.933.613.61
344.371.641.64
419.481.411.41
449.963.213.21
459.353.343.34
336.383.913.91
523.575.195.19
344.442.962.96
541.673.633.63
343.842.312.31
412.473.453.45
364.434.474.47
235.352.862.86
305.362.292.29
305.333.633.63
232.113.193.19
401.382.092.09
365.393.663.66
380.353.703.70
367.182.522.52
252.273.413.41
494.043.143.14
388.222.932.93
413.483.083.08
334.654.464.46
275.09
224.240.410.41
540.112.602.60
267.631.221.22
377.245.935.93
431.285.365.36
426.483.553.55
429.402.982.98
257.313.763.76
439.332.652.65
327.341.731.73
336.353.123.12
444.442.592.59
337.814.474.47
382.344.194.19
359.333.003.00
253.352.682.68
445.572.672.67
359.232.822.82
346.694.214.21
172.190.800.80
270.292.092.09
291.342.152.15
365.352.242.24
243.062.332.33
260.153.463.46
384.863.473.47
277.783.303.30
215.261.841.84
490.595.015.01
246.271.061.06
426.903.793.79
343.394.764.76
358.851.931.93
416.864.784.78
383.705.335.33
317.782.522.52
151.231.511.51
195.221.521.52
494.043.773.77
279.753.293.29
345.903.543.54
536.593.703.70
290.244.644.64
454.513.513.51
481.604.714.71
353.383.363.36
295.433.513.51
289.162.882.88
329.213.943.94
239.322.292.29
381.595.395.39
366.244.614.61
470.384.264.26
271.302.752.75
401.441.851.85
371.422.772.77
425.921.571.57
380.834.054.05
292.291.171.17
377.422.972.97
357.443.113.11
365.464.714.71
274.200.730.73
410.472.122.12
407.453.103.10
358.752.782.78
341.292.702.70
423.333.413.41
380.363.793.79
417.944.394.39
284.143.823.82
458.553.553.55
350.362.192.19
212.641.521.52
862.75-1.10-1.10
234.082.852.85
394.213.303.30
410.744.324.32
235.672.892.89
387.443.333.33
360.393.223.22
263.772.612.61
377.302.672.67
280.240.400.40
353.360.730.73
449.382.892.89
362.282.212.21
405.294.974.97
386.792.592.59
454.502.502.50
347.824.414.41
396.451.731.73
303.311.911.91
410.453.273.27
247.353.053.05
304.253.033.03
251.292.232.23
359.452.632.63
277.722.592.59
285.322.842.84
264.313.283.28
487.515.415.41
279.371.601.60
347.833.373.37
217.222.202.20
361.392.932.93
345.363.323.32
398.892.902.90
341.443.403.40
461.571.911.91
468.293.573.57
287.283.423.42
247.693.383.38
229.242.602.60
336.341.571.57
418.481.711.71
269.133.553.55
232.283.373.37
300.702.482.48
331.312.932.93
242.241.471.47
374.504.614.61
401.423.583.58
416.893.423.42
249.733.283.28
378.192.572.57
318.762.972.97
303.792.852.85
289.342.832.83
333.372.952.95
458.453.573.57
362.411.721.72
357.414.104.10
379.724.744.74
273.252.012.01
217.660.970.97
403.754.404.40
254.123.973.97
360.802.732.73
404.345.395.39
328.201.531.53
372.413.003.00
277.672.902.90
427.495.185.18
287.734.034.03
505.623.973.97
413.462.122.12
378.883.263.26
389.882.872.87
327.762.592.59
335.413.103.10
368.704.584.58
274.183.713.71
426.494.224.22
389.883.393.39
265.702.162.16
437.952.602.60
303.753.043.04
277.672.902.90
331.202.212.21
280.351.891.89
315.763.273.27
266.563.413.41
234.312.512.51
237.652.492.49
354.233.743.74
286.324.084.08
288.233.023.02
421.863.453.45
346.272.072.07
399.863.323.32
440.314.274.27
360.832.442.44
400.512.682.68
382.381.491.49
412.313.653.65
362.432.792.79
236.731.941.94
462.503.483.48
450.903.753.75
337.202.762.76
410.744.544.54
382.171.601.60
351.862.662.66
317.694.644.64
450.483.253.25
335.453.663.66
370.483.163.16
456.314.114.11
438.462.722.72
204.273.003.00
466.562.902.90
446.492.862.86
301.261.241.24
316.413.023.02
307.133.553.55
355.444.294.29
554.054.704.70
312.352.682.68
313.262.762.76
333.821.991.99
354.162.202.20
329.814.064.06
245.283.193.19
402.863.113.11
360.371.841.84
319.294.144.14
486.552.612.61
363.485.305.30
393.834.394.39
280.282.132.13
339.422.372.37
425.472.832.83
366.463.563.56
230.272.072.07
357.404.094.09
268.812.652.65
497.572.862.86
429.333.203.20
474.501.391.39
375.813.893.89
409.552.682.68
421.431.631.63
317.371.711.71
267.693.763.76
297.772.732.73
288.393.313.31
265.724.104.10
320.402.612.61
341.193.213.21
431.542.572.57
318.762.642.64
406.513.073.07
437.313.773.77
328.762.292.29
430.913.743.74
322.823.503.50
498.561.551.55
296.282.212.21
200.250.590.59
389.423.303.30
267.282.472.47
364.734.064.06
349.343.423.42
411.893.673.67
432.272.962.96
405.274.054.05
330.343.673.67
373.413.803.80
315.724.644.64
427.605.145.14
266.442.332.33
279.302.422.42
430.263.493.49
398.463.893.89
298.662.222.22
396.444.284.28
282.352.272.27
322.412.062.06
388.513.543.54
377.371.811.81
394.882.542.54
201.632.832.83
336.353.063.06
260.303.133.13
393.755.055.05
292.362.872.87
634.46-0.30-0.30
406.313.783.78
383.862.922.92
319.262.282.28
360.282.012.01
305.163.753.75
319.672.092.09
444.453.023.02
382.831.671.67
444.493.513.51
177.200.740.74
322.413.253.25
430.443.183.18
236.252.672.67
262.272.652.65
291.234.454.45
234.692.292.29
355.254.814.81
442.323.473.47
331.461.851.85
255.152.672.67
255.641.851.85
330.342.442.44
436.512.672.67
349.183.723.72
273.312.562.56
263.291.851.85
381.861.291.29
347.423.503.50
307.732.342.34
559.264.544.54
326.193.283.28
403.493.133.13
243.142.472.47
398.381.191.19
448.524.094.09
465.414.884.88
307.424.094.09
350.241.591.59
351.341.261.26
312.442.892.89
361.203.443.44
326.743.273.27
260.143.513.51
441.893.753.75
432.314.074.07
330.791.151.15
361.853.683.68
462.512.472.47
459.512.722.72
244.090.850.85
325.782.632.63
356.383.663.66
446.360.140.14
340.773.333.33
646.33-1.63-1.63
439.543.133.13
302.281.321.32
354.504.524.52
358.405.065.06
409.455.125.12
335.394.684.68
340.213.943.94
335.394.514.51
272.262.742.74
394.335.045.04
299.350.670.67
280.283.413.41
311.673.583.58
323.383.203.20
278.313.943.94
400.512.732.73
305.402.132.13
402.862.922.92
419.914.554.55
258.112.132.13
322.413.953.95
447.313.223.22
332.663.823.82
335.644.744.74
391.452.562.56
250.712.682.68
443.283.743.74
219.663.093.09
315.312.732.73
255.152.672.67
455.453.653.65
378.413.393.39
468.564.824.82
289.723.003.00
522.613.983.98
198.221.231.23
288.693.483.48
382.892.952.95
375.381.021.02
309.322.382.38
275.162.992.99
308.383.703.70
296.353.923.92
260.273.653.65
465.144.154.15
350.403.663.66
352.393.163.16
471.604.724.72
303.713.103.10
302.274.544.54
489.622.502.50
353.363.983.98
369.453.563.56
351.794.194.19
301.204.094.09
492.513.243.24
382.424.224.22
329.311.611.61
310.433.783.78
291.782.382.38
323.383.203.20
324.163.653.65
253.663.073.07
347.372.162.16
319.363.173.17
452.563.293.29
342.463.153.15
388.542.552.55
335.394.514.51
378.861.711.71
303.293.103.10
433.554.254.25
491.373.673.67
412.433.673.67
302.281.321.32
227.271.671.67
477.503.863.86
280.952.802.80
486.984.404.40
514.523.953.95
252.273.413.41
403.853.573.57
280.694.004.00
353.373.473.47
569.604.834.83
425.403.153.15
342.382.512.51
281.143.323.32
403.503.663.66
337.284.154.15
250.371.711.71
312.153.293.29
280.742.952.95
264.373.813.81
326.224.234.23
330.482.222.22
326.382.742.74
366.704.094.09
486.512.242.24
199.640.740.74
402.503.683.68
235.321.811.81
354.674.194.19
340.293.993.99
380.324.284.28
436.553.533.53
436.534.864.86
353.331.901.90
297.233.163.16
256.332.022.02
364.470.910.91
406.512.792.79
232.241.671.67
378.393.923.92
480.471.571.57
404.463.933.93
330.413.063.06
463.323.903.90
361.853.683.68
377.471.881.88
277.783.223.22
282.772.662.66
342.261.961.96
348.502.552.55
288.252.222.22
214.671.811.81
329.352.722.72
503.633.443.44
428.543.543.54
264.282.472.47
330.173.053.05
297.143.413.41
353.381.961.96
347.873.183.18
331.372.852.85
496.952.882.88
260.153.023.02
306.163.763.76
331.722.342.34
254.123.403.40
306.340.720.72
416.422.872.87
246.273.603.60
373.212.322.32
374.703.543.54
340.231.521.52
494.910.780.78
343.312.132.13
441.472.982.98
319.311.771.77
342.783.133.13
494.911.741.74
426.522.732.73
435.893.763.76
536.634.374.37
310.311.761.76
342.463.823.82
245.283.193.19
428.433.523.52
220.231.501.50
416.492.662.66
504.731.781.78
365.014.224.22
477.523.073.07
268.272.692.69
342.782.842.84
381.822.782.78
296.232.022.02
453.373.583.58
263.303.803.80
229.242.602.60
362.883.713.71
481.961.971.97
382.744.344.34
301.261.461.46
224.312.162.16
331.803.703.70
392.335.035.03
448.272.982.98
246.262.792.79
237.282.102.10
208.692.632.63
334.253.933.93
315.802.762.76
315.174.294.29
359.412.872.87
270.123.683.68
245.282.232.23
284.361.041.04
391.472.152.15
396.264.104.10
325.265.645.64
296.290.990.99
180.241.031.03
452.942.512.51
314.123.873.87
426.384.604.60
261.353.263.26
169.181.731.73
349.394.194.19
296.39-1.11-1.11
348.362.862.86
268.733.923.92
390.323.543.54
340.792.002.00
271.302.842.84
374.823.123.12
256.133.333.33
466.933.123.12
418.863.143.14
270.152.472.47
426.902.712.71
292.273.063.06
314.332.312.31
170.601.831.83
387.403.223.22
313.793.133.13
260.280.350.35
382.962.062.06
417.495.115.11
378.704.044.04
211.202.132.13
323.833.403.40
478.551.051.05
440.983.123.12
315.233.753.75
366.432.542.54
292.381.751.75
351.363.553.55
340.141.901.90
270.123.523.52
377.443.653.65
259.703.463.46
348.792.442.44
263.273.333.33
421.283.843.84
510.393.793.79
334.723.273.27
427.453.383.38
438.552.662.66
524.374.094.09
359.432.912.91
421.542.132.13
248.313.583.58
265.172.682.68
354.371.851.85
396.305.085.08
405.503.013.01
445.482.492.49
407.303.543.54
229.763.803.80
214.222.582.58
339.184.364.36
355.484.264.26
423.922.462.46
297.343.163.16
319.341.161.16
492.563.283.28
319.311.771.77
332.792.022.02
461.282.552.55
373.373.273.27
349.412.812.81
372.403.393.39
411.312.502.50
328.332.072.07
367.794.494.49
391.433.533.53
291.362.492.49
383.432.902.90
176.171.641.64
285.733.043.04
409.512.742.74
357.363.033.03
284.173.933.93
357.843.903.90
389.263.703.70
300.343.263.26
325.782.632.63
427.572.632.63
307.352.012.01
287.703.923.92
359.182.402.40
461.343.533.53
361.423.053.05
365.374.054.05
410.952.512.51
422.422.162.16
331.204.724.72
283.352.432.43
507.68
335.453.113.11
385.473.733.73
343.434.784.78
180.211.971.97
362.235.495.49
357.162.722.72
326.224.234.23
476.992.242.24
264.392.012.01
378.583.273.27
355.872.892.89
265.683.523.52
466.973.883.88
243.291.621.62
582.482.892.89
369.45-0.51-0.51
396.202.462.46
311.245.335.33
592.653.313.31
357.815.135.13
470.334.424.42
245.260.520.52
431.492.272.27
421.335.295.29
386.382.852.85
449.514.244.24
448.522.842.84
292.172.052.05
311.173.583.58
248.113.243.24
372.242.522.52
299.242.372.37
483.481.781.78
207.662.172.17
381.152.042.04
247.353.053.05
368.402.242.24
437.314.224.22
349.752.192.19
402.843.173.17
371.351.841.84
283.331.701.70
399.482.792.79
390.401.831.83
296.281.831.83
332.412.772.77
418.482.822.82
404.473.543.54
293.712.472.47
396.402.712.71
426.502.832.83
497.585.895.89
401.482.812.81
400.220.940.94
413.464.704.70
381.554.274.27
385.282.352.35
366.401.971.97
272.262.942.94
277.373.733.73
289.593.323.32
409.442.612.61
342.182.992.99
504.913.963.96
231.252.242.24
282.351.311.31
305.994.004.00
451.931.951.95
270.291.741.74
313.352.592.59
445.502.442.44
273.333.813.81
278.170.720.72
335.863.133.13
261.372.432.43
274.232.052.05
382.464.504.50
393.852.702.70
348.502.552.55
312.234.734.73
328.392.752.75
221.652.582.58
214.222.582.58
303.341.461.46
281.143.573.57
254.293.703.70
326.472.642.64
268.222.442.44
263.411.681.68
288.353.083.08
261.712.892.89
498.875.115.11
438.963.113.11
498.433.223.22
234.282.072.07
506.975.435.43
552.683.643.64
298.302.232.23
272.261.961.96
368.330.800.80
316.322.632.63
413.462.432.43
299.311.861.86
504.555.145.14
248.672.282.28
399.254.134.13
356.822.392.39
325.393.443.44
312.162.852.85
326.311.711.71
403.443.433.43
343.361.851.85
230.221.981.98
307.813.473.47
346.414.524.52
527.605.495.49
328.321.691.69
438.421.181.18
443.572.932.93
378.823.753.75
375.732.032.03
298.251.431.43
322.193.473.47
318.172.542.54
273.251.881.88
297.342.772.77
382.381.881.88
354.372.252.25
288.732.742.74
388.362.252.25
422.812.902.90
360.803.593.59
296.371.991.99
319.393.603.60
304.331.521.52
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