Basic Information
ID: ALA1738197
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose response confirmation of uHTS of chemical inhibitors of both B-cell and T-cell specific antigen receptor-induced NF-kB activation in a Jurkat cell line using a luminescence assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID435003, AID435022, AID465, AID489029]
Organism: Homo sapiens
Cell type: Jurkat
Activity Charts
Bioactivity
Activity Types for Assay ALA1738197
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 396.44 | 3.78 | 3.78 |
| 266.26 | -1.38 | -1.38 |
| 285.69 | -0.30 | -0.30 |
| 243.22 | -2.56 | -2.56 |
| 285.24 | -1.84 | -1.84 |
| 355.83 | 3.73 | 3.73 |
| 357.35 | 2.78 | 2.78 |
| 492.45 | 5.70 | 5.70 |
| 262.30 | 1.25 | 1.25 |
| 366.41 | 1.12 | 1.12 |
| 265.31 | 0.50 | 0.50 |
| 364.94 | 5.24 | 5.24 |
| 299.33 | 4.47 | 4.47 |
| 304.34 | 1.82 | 1.82 |
| 364.78 | 2.69 | 2.69 |
| 614.56 | 7.32 | 7.32 |
| 579.99 | 0.00 | 0.00 |
| 517.11 | 4.94 | 4.94 |
| 458.55 | 2.91 | 2.91 |
| 285.69 | -0.30 | -0.30 |
| 339.32 | 3.53 | 3.53 |
| 301.42 | 4.45 | 4.45 |
| 415.72 | 5.98 | 5.98 |
| 287.25 | 3.33 | 3.33 |
| 301.82 | 2.74 | 2.74 |
| 319.86 | 4.43 | 4.43 |
| 418.07 | 6.61 | 6.61 |
| 462.52 | 6.52 | 6.52 |
| 301.27 | 3.72 | 3.72 |
| 320.22 | 2.94 | 2.94 |
| 533.96 | 1.02 | 1.02 |
| 579.99 | 0.00 | 0.00 |
| 340.45 | 5.33 | 5.33 |
| 255.35 | 3.86 | 3.86 |
| 344.81 | 3.39 | 3.39 |
| 351.36 | 1.89 | 1.89 |
| 356.82 | 3.12 | 3.12 |
| 329.49 | 3.68 | 3.68 |
| 478.55 | 2.57 | 2.57 |
| 260.30 | 1.94 | 1.94 |
| 389.25 | 4.58 | 4.58 |
| 367.36 | 3.45 | 3.45 |
| 259.19 | 2.55 | 2.55 |
| 333.39 | 2.60 | 2.60 |
| 393.19 | 4.26 | 4.26 |
| 281.35 | 1.04 | 1.04 |
| 440.59 | 3.54 | 3.54 |
| 351.44 | 2.37 | 2.37 |
| 382.49 | 3.52 | 3.52 |
| 333.44 | 2.74 | 2.74 |
| 382.53 | 3.82 | 3.82 |
| 292.36 | 1.96 | 1.96 |
| 286.29 | 3.04 | 3.04 |
| 297.35 | 2.82 | 2.82 |
| 424.33 | 3.54 | 3.54 |
| 474.41 | 5.39 | 5.39 |
| 281.74 | 2.36 | 2.36 |
| 301.32 | 2.57 | 2.57 |
| 319.42 | 2.35 | 2.35 |
| 416.45 | 4.90 | 4.90 |
| 342.38 | 2.93 | 2.93 |
| 481.56 | 2.82 | 2.82 |
| 337.42 | 2.76 | 2.76 |
| 354.45 | 2.77 | 2.77 |
| 502.47 | 6.00 | 6.00 |
| 474.41 | 5.39 | 5.39 |
| 530.66 | 3.01 | 3.01 |
| 402.95 | 4.16 | 4.16 |
| 484.61 | 5.99 | 5.99 |
| 351.41 | 3.04 | 3.04 |
| 443.01 | 4.04 | 4.04 |
| 380.48 | 3.31 | 3.31 |
| 329.27 | 1.87 | 1.87 |
| 315.40 | 3.36 | 3.36 |
| 432.59 | 5.37 | 5.37 |
| 315.35 | 2.02 | 2.02 |
| 314.37 | 3.57 | 3.57 |
| 342.90 | 2.31 | 2.31 |
| 372.45 | 3.29 | 3.29 |
| 258.32 | 2.49 | 2.49 |
| 464.54 | 2.18 | 2.18 |
| 481.51 | 7.61 | 7.61 |
| 274.32 | 2.03 | 2.03 |
| 273.38 | 3.53 | 3.53 |
| 417.87 | 3.80 | 3.80 |
| 387.45 | 5.79 | 5.79 |
| 443.39 | 4.57 | 4.57 |
| 377.27 | 4.47 | 4.47 |
| 380.44 | 4.71 | 4.71 |
| 448.97 | 3.53 | 3.53 |
| 267.29 | 2.82 | 2.82 |
| 438.21 | 4.15 | 4.15 |
| 389.33 | 4.51 | 4.51 |
| 412.51 | 3.53 | 3.53 |
| 380.29 | 3.65 | 3.65 |
| 293.48 | 4.41 | 4.41 |
| 418.32 | 4.34 | 4.34 |
| 253.26 | 2.81 | 2.81 |
| 278.33 | 2.80 | 2.80 |
| 329.48 | 5.01 | 5.01 |
| 333.44 | 2.59 | 2.59 |
| 326.81 | 2.61 | 2.61 |
| 307.42 | 3.49 | 3.49 |
| 357.36 | 2.69 | 2.69 |
| 413.36 | 4.48 | 4.48 |
| 297.36 | 2.40 | 2.40 |
| 324.38 | 4.06 | 4.06 |
| 313.38 | 3.55 | 3.55 |
| 235.22 | 2.29 | 2.29 |
| 358.42 | 2.32 | 2.32 |
| 431.44 | 3.18 | 3.18 |
| 386.47 | 3.37 | 3.37 |
| 276.36 | 3.23 | 3.23 |
| 352.87 | 3.59 | 3.59 |
| 287.34 | 2.16 | 2.16 |
| 325.41 | 3.95 | 3.95 |
| 465.98 | 3.22 | 3.22 |
| 357.41 | 0.63 | 0.63 |
| 315.38 | 3.65 | 3.65 |
| 359.43 | 1.79 | 1.79 |
| 503.08 | 5.74 | 5.74 |
| 339.37 | 2.55 | 2.55 |
| 301.34 | 3.46 | 3.46 |
| 331.35 | 1.72 | 1.72 |
| 402.36 | 3.81 | 3.81 |
| 343.35 | 4.89 | 4.89 |
| 432.56 | 1.68 | 1.68 |
| 274.32 | 3.76 | 3.76 |
| 530.66 | 3.01 | 3.01 |
| 478.51 | 2.13 | 2.13 |
| 300.27 | 2.76 | 2.76 |
| 373.39 | 1.88 | 1.88 |
| 451.45 | 5.00 | 5.00 |
| 257.38 | 4.40 | 4.40 |
| 459.55 | 3.09 | 3.09 |
| 592.64 | 3.00 | 3.00 |
| 535.13 | 4.94 | 4.94 |
| 480.61 | 2.27 | 2.27 |
| 474.41 | 5.39 | 5.39 |
| 327.30 | -2.28 | -2.28 |
| 447.61 | 4.22 | 4.22 |
| 267.28 | 3.04 | 3.04 |
| 290.71 | 3.68 | 3.68 |
| 365.89 | 3.67 | 3.67 |
| 359.36 | 1.49 | 1.49 |
| 412.51 | 3.53 | 3.53 |
| 524.06 | 4.13 | 4.13 |
| 300.31 | 3.43 | 3.43 |
| 474.92 | 4.50 | 4.50 |
| 330.34 | 3.07 | 3.07 |
| 558.71 | 3.50 | 3.50 |
| 501.65 | 4.20 | 4.20 |
| 354.37 | 0.49 | 0.49 |
| 410.42 | 2.84 | 2.84 |
| 261.67 | -1.42 | -1.42 |
| 805.01 | 5.21 | 5.21 |
| 355.39 | 2.57 | 2.57 |
| 357.41 | 3.03 | 3.03 |
| 362.49 | 5.08 | 5.08 |
| 300.36 | 3.10 | 3.10 |
| 390.47 | 3.70 | 3.70 |
| 280.78 | 2.57 | 2.57 |
| 448.44 | 3.63 | 3.63 |
| 348.83 | 4.49 | 4.49 |
| 576.62 | 4.56 | 4.56 |
| 335.64 | 3.57 | 3.57 |
| 301.20 | 2.92 | 2.92 |
| 345.38 | 2.42 | 2.42 |