Basic Information
ID: ALA1738253
Type: Binding
Description: PUBCHEM_BIOASSAY: Ras-converting Enzyme/Cell Proliferation Pathway Measured in Biochemical System Using Plate Reader - 2034-01_Inhibitor_Dose_CherryPick. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2618]
Organism: Saccharomyces cerevisiae S288c
Activity Charts
Bioactivity
Activity Types for Assay ALA1738253
AC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 361.37 | 1.54 | 1.54 |
| 195.17 | 0.88 | 0.88 |
| 505.46 | 4.18 | 4.18 |
| 282.34 | 2.39 | 2.39 |
| 337.81 | 4.43 | 4.43 |
| 219.20 | 1.65 | 1.65 |
| 298.39 | 5.04 | 5.04 |
| 440.97 | 5.39 | 5.39 |
| 476.54 | 6.83 | 6.83 |
| 319.38 | 2.17 | 2.17 |
| 364.87 | 2.14 | 2.14 |
| 453.52 | 2.34 | 2.34 |
| 396.49 | 4.94 | 4.94 |
| 437.56 | 5.29 | 5.29 |
| 375.79 | 3.41 | 3.41 |
| 284.28 | 1.56 | 1.56 |
| 324.38 | 4.35 | 4.35 |
| 460.47 | 2.58 | 2.58 |
| 285.30 | 2.19 | 2.19 |
| 274.35 | 1.77 | 1.77 |
| 464.52 | 2.78 | 2.78 |
| 358.42 | 3.76 | 3.76 |
| 490.40 | 6.14 | 6.14 |
| 410.47 | 2.14 | 2.14 |
| 282.34 | 3.09 | 3.09 |
| 462.53 | 5.54 | 5.54 |
| 304.39 | 4.92 | 4.92 |
| 430.62 | 5.12 | 5.12 |
| 331.25 | 5.03 | 5.03 |
| 444.34 | 5.55 | 5.55 |
| 434.49 | 5.57 | 5.57 |
| 397.48 | 2.45 | 2.45 |
| 541.92 | 4.18 | 4.18 |
| 623.11 | 5.14 | 5.14 |
| 247.25 | 1.26 | 1.26 |
| 463.58 | 4.16 | 4.16 |
| 503.08 | 5.74 | 5.74 |
| 433.41 | 4.26 | 4.26 |
| 399.28 | 3.25 | 3.25 |
| 423.52 | 4.87 | 4.87 |
| 333.35 | 3.28 | 3.28 |
| 314.37 | 2.73 | 2.73 |
| 344.33 | 1.22 | 1.22 |
| 488.50 | 5.12 | 5.12 |
| 456.01 | 4.97 | 4.97 |
| 414.30 | 4.83 | 4.83 |
| 251.24 | 1.89 | 1.89 |
| 318.21 | 3.82 | 3.82 |
| 308.40 | 1.98 | 1.98 |
| 373.41 | 2.08 | 2.08 |
| 323.35 | 3.29 | 3.29 |
| 449.50 | 3.70 | 3.70 |
| 511.61 | 6.42 | 6.42 |
| 490.85 | 5.42 | 5.42 |
| 386.84 | 3.89 | 3.89 |
| 435.87 | 5.25 | 5.25 |
| 312.38 | 4.24 | 4.24 |
| 269.35 | 2.82 | 2.82 |
| 350.40 | 2.24 | 2.24 |
| 410.45 | 3.27 | 3.27 |
| 487.08 | 6.04 | 6.04 |
| 286.29 | 1.84 | 1.84 |
| 313.36 | 4.36 | 4.36 |
| 292.43 | 2.86 | 2.86 |
| 277.33 | 3.35 | 3.35 |
| 400.55 | 3.77 | 3.77 |
| 334.38 | 2.74 | 2.74 |
| 377.87 | 3.21 | 3.21 |
| 380.38 | 3.15 | 3.15 |
| 316.20 | 4.19 | 4.19 |
| 186.17 | 1.38 | 1.38 |
| 414.55 | 3.86 | 3.86 |
| 445.51 | 3.60 | 3.60 |
| 380.45 | -0.30 | -0.30 |
| 359.82 | 1.77 | 1.77 |
| 320.25 | 3.55 | 3.55 |
| 299.40 | 3.05 | 3.05 |
| 368.52 | 3.54 | 3.54 |
| 251.31 | 1.66 | 1.66 |
| 328.80 | 3.97 | 3.97 |
| 502.25 | 5.32 | 5.32 |
| 281.16 | 3.25 | 3.25 |
| 355.78 | 4.03 | 4.03 |
| 295.34 | 2.91 | 2.91 |
| 356.81 | 4.18 | 4.18 |
| 295.34 | 2.91 | 2.91 |
| 488.03 | 5.59 | 5.59 |
| 261.33 | 4.57 | 4.57 |
| 380.43 | 2.58 | 2.58 |
| 493.59 | 3.85 | 3.85 |
| 331.25 | 5.03 | 5.03 |
| 417.46 | 2.13 | 2.13 |
| 256.30 | 3.33 | 3.33 |
| 462.52 | 6.52 | 6.52 |
| 345.40 | 2.90 | 2.90 |
| 301.18 | 0.69 | 0.69 |
| 505.01 | 4.90 | 4.90 |
| 236.26 | 1.78 | 1.78 |
| 319.74 | 3.33 | 3.33 |
| 381.41 | 2.60 | 2.60 |
| 367.40 | 3.01 | 3.01 |
| 468.56 | 4.14 | 4.14 |
| 411.50 | 3.77 | 3.77 |
| 456.50 | 2.78 | 2.78 |
| 323.35 | 2.64 | 2.64 |
| 435.28 | 5.18 | 5.18 |
| 400.46 | 3.45 | 3.45 |
| 410.43 | 4.14 | 4.14 |
| 451.53 | 5.44 | 5.44 |
| 316.31 | 3.05 | 3.05 |
| 232.21 | 2.90 | 2.90 |
| 429.41 | 1.14 | 1.14 |
| 312.38 | 4.10 | 4.10 |
| 411.51 | 2.89 | 2.89 |
| 466.34 | 4.85 | 4.85 |
| 279.32 | 2.45 | 2.45 |
| 425.92 | 4.79 | 4.79 |
| 392.51 | 2.95 | 2.95 |
| 340.43 | 2.38 | 2.38 |
| 540.62 | 5.24 | 5.24 |
| 408.46 | 3.73 | 3.73 |
| 341.25 | 4.16 | 4.16 |
| 354.41 | 2.51 | 2.51 |
| 418.52 | 1.32 | 1.32 |
| 575.14 | 5.52 | 5.52 |
| 523.62 | 6.65 | 6.65 |
| 601.24 | 5.72 | 5.72 |
| 394.47 | 3.23 | 3.23 |
| 430.53 | 2.85 | 2.85 |
| 359.38 | 2.06 | 2.06 |
| 500.60 | 3.71 | 3.71 |
| 417.52 | 3.23 | 3.23 |
| 421.49 | 4.36 | 4.36 |
| 368.41 | 3.18 | 3.18 |
| 415.52 | 3.96 | 3.96 |
| 324.79 | 2.96 | 2.96 |
| 403.48 | 3.65 | 3.65 |
| 339.40 | 3.31 | 3.31 |
| 410.48 | 4.72 | 4.72 |
| 453.59 | 5.97 | 5.97 |
| 263.30 | 2.93 | 2.93 |
| 377.27 | 4.47 | 4.47 |
| 469.52 | 5.01 | 5.01 |
| 479.65 | 5.66 | 5.66 |
| 181.19 | 0.79 | 0.79 |
| 289.18 | 3.31 | 3.31 |
| 349.23 | 2.48 | 2.48 |
| 428.53 | 2.70 | 2.70 |
| 489.94 | 4.59 | 4.59 |
| 542.08 | 5.19 | 5.19 |
| 429.95 | 4.80 | 4.80 |
| 398.87 | 5.72 | 5.72 |
| 399.20 | 4.80 | 4.80 |
| 442.55 | 4.71 | 4.71 |
| 303.17 | 3.49 | 3.49 |
| 424.50 | 4.93 | 4.93 |
| 414.91 | 3.92 | 3.92 |
| 413.48 | 4.19 | 4.19 |
| 359.39 | 4.05 | 4.05 |
| 208.24 | 1.67 | 1.67 |
| 386.48 | 5.06 | 5.06 |
| 474.57 | 2.83 | 2.83 |
| 487.08 | 6.04 | 6.04 |
| 231.29 | 1.63 | 1.63 |
| 388.52 | 3.80 | 3.80 |
| 511.50 | 4.18 | 4.18 |
| 309.37 | 2.64 | 2.64 |
| 390.71 | 4.58 | 4.58 |
| 351.40 | 4.53 | 4.53 |
| 387.46 | 5.87 | 5.87 |
| 435.37 | 3.23 | 3.23 |
| 287.34 | 2.01 | 2.01 |
| 267.33 | 3.36 | 3.36 |
| 256.31 | 2.21 | 2.21 |
| 422.53 | 4.46 | 4.46 |
| 405.50 | 3.64 | 3.64 |
| 542.98 | 6.93 | 6.93 |
| 380.36 | 2.57 | 2.57 |
| 475.25 | 3.68 | 3.68 |
| 517.55 | 6.03 | 6.03 |
| 315.44 | 3.53 | 3.53 |
| 245.28 | 1.70 | 1.70 |
| 403.48 | 3.29 | 3.29 |
| 407.45 | 4.25 | 4.25 |
| 353.42 | 4.02 | 4.02 |
| 399.52 | 2.23 | 2.23 |
| 324.38 | 2.76 | 2.76 |
| 466.99 | 3.55 | 3.55 |
| 184.20 | 1.48 | 1.48 |
| 567.67 | 3.69 | 3.69 |
| 265.31 | 3.39 | 3.39 |
| 349.26 | 4.48 | 4.48 |
| 283.37 | 3.62 | 3.62 |
| 436.46 | 4.42 | 4.42 |
| 495.58 | 3.14 | 3.14 |
| 431.99 | 3.32 | 3.32 |
| 364.85 | 3.24 | 3.24 |
| 405.46 | 5.44 | 5.44 |
| 464.52 | 2.55 | 2.55 |
| 441.58 | 5.45 | 5.45 |
| 241.29 | 2.53 | 2.53 |
| 376.89 | 4.85 | 4.85 |
| 551.08 | 9.23 | 9.23 |
| 437.56 | 7.05 | 7.05 |
| 435.48 | 1.98 | 1.98 |
| 483.71 | 3.76 | 3.76 |
| 317.42 | 4.76 | 4.76 |
| 394.48 | 4.26 | 4.26 |
| 400.55 | 3.77 | 3.77 |
| 483.62 | 2.81 | 2.81 |
| 434.48 | 2.36 | 2.36 |
| 420.51 | 2.55 | 2.55 |
| 475.59 | 3.97 | 3.97 |
| 248.29 | 2.88 | 2.88 |
| 210.24 | 2.02 | 2.02 |
| 548.66 | 6.54 | 6.54 |
| 232.24 | 1.82 | 1.82 |
| 380.44 | 2.92 | 2.92 |
| 239.28 | 1.99 | 1.99 |
| 475.66 | 3.44 | 3.44 |
| 351.40 | 3.31 | 3.31 |
| 345.82 | 2.00 | 2.00 |
| 308.45 | 2.86 | 2.86 |
| 519.56 | 3.37 | 3.37 |
| 495.53 | 3.97 | 3.97 |
| 434.50 | 2.38 | 2.38 |
| 442.61 | 3.80 | 3.80 |
| 410.42 | 4.99 | 4.99 |
| 379.50 | 4.13 | 4.13 |
| 429.55 | 4.93 | 4.93 |
| 367.43 | 3.71 | 3.71 |
| 301.37 | 3.88 | 3.88 |
| 366.49 | 5.56 | 5.56 |
| 520.65 | 5.74 | 5.74 |
| 484.42 | 4.48 | 4.48 |
| 452.39 | 5.94 | 5.94 |
| 309.36 | 3.30 | 3.30 |
| 458.00 | 5.58 | 5.58 |
| 537.05 | 8.84 | 8.84 |
| 413.57 | 4.11 | 4.11 |
| 358.42 | 3.30 | 3.30 |
| 378.27 | 4.16 | 4.16 |
| 384.44 | 3.60 | 3.60 |
| 444.99 | 3.06 | 3.06 |
| 419.98 | 5.90 | 5.90 |
| 234.28 | 2.59 | 2.59 |
| 418.47 | 2.32 | 2.32 |
| 437.93 | 3.94 | 3.94 |
| 215.26 | 1.70 | 1.70 |
| 523.57 | 2.17 | 2.17 |
| 497.98 | 7.27 | 7.27 |
| 237.26 | 3.08 | 3.08 |
| 359.38 | 2.11 | 2.11 |
| 499.36 | 4.23 | 4.23 |
| 384.41 | 2.04 | 2.04 |
| 385.37 | 3.35 | 3.35 |
| 348.87 | 4.54 | 4.54 |
| 415.49 | 4.02 | 4.02 |
| 436.51 | 7.46 | 7.46 |
| 417.46 | 2.82 | 2.82 |
| 418.50 | 2.19 | 2.19 |
| 331.42 | 4.36 | 4.36 |
| 375.35 | 3.47 | 3.47 |
| 387.46 | 1.74 | 1.74 |
| 519.78 | 4.57 | 4.57 |
| 425.99 | 4.97 | 4.97 |
| 457.48 | 3.25 | 3.25 |
| 447.79 | 6.57 | 6.57 |
| 405.47 | 4.19 | 4.19 |
| 297.41 | 2.88 | 2.88 |
| 539.66 | 7.20 | 7.20 |
| 278.35 | 2.73 | 2.73 |
| 451.54 | 3.52 | 3.52 |
| 379.38 | 1.60 | 1.60 |
| 390.41 | 2.27 | 2.27 |
| 424.45 | 2.12 | 2.12 |
| 489.35 | 3.60 | 3.60 |
| 434.49 | 2.60 | 2.60 |
| 457.49 | 4.62 | 4.62 |
| 422.84 | 2.63 | 2.63 |
| 424.45 | 2.04 | 2.04 |
| 448.48 | 3.12 | 3.12 |
| 424.45 | 2.12 | 2.12 |
| 370.52 | 3.54 | 3.54 |
| 314.35 | 1.23 | 1.23 |
| 374.87 | 3.91 | 3.91 |
| 357.41 | 4.28 | 4.28 |
| 477.45 | 2.25 | 2.25 |
| 387.41 | 4.97 | 4.97 |
| 344.34 | 1.02 | 1.02 |
| 489.34 | 0.51 | 0.51 |
| 470.85 | 2.85 | 2.85 |
| 346.38 | 1.18 | 1.18 |
| 346.35 | 0.45 | 0.45 |
| 328.76 | 2.37 | 2.37 |
| 359.43 | 2.87 | 2.87 |
| 292.34 | 2.82 | 2.82 |
| 360.40 | 1.49 | 1.49 |
| 440.57 | 2.51 | 2.51 |
| 317.19 | 3.52 | 3.52 |