ID: ALA1738319
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose Response confirmation of inhibitors of hexokinase domain containing I (HKDC1) in the hexokinase 1 selectivity assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493160, AID493190]
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA1738319
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
347.33 | 0.31 | 0.31 |
505.46 | 4.18 | 4.18 |
173.17 | 0.75 | 0.75 |
310.40 | 1.73 | 1.73 |
168.15 | 0.20 | 0.20 |
186.21 | 1.34 | 1.34 |
317.28 | 3.80 | 3.80 |
862.75 | -1.10 | -1.10 |
381.38 | 3.49 | 3.49 |
424.51 | 3.42 | 3.42 |
487.94 | 4.50 | 4.50 |
417.41 | 1.72 | 1.72 |
357.81 | 0.68 | 0.68 |
369.76 | 3.27 | 3.27 |
453.56 | 3.31 | 3.31 |
410.43 | 2.70 | 2.70 |
327.38 | 3.75 | 3.75 |
318.76 | 1.71 | 1.71 |
335.34 | 2.69 | 2.69 |
336.34 | 3.09 | 3.09 |
282.34 | 3.09 | 3.09 |
386.28 | 2.32 | 2.32 |
371.42 | 3.48 | 3.48 |
453.56 | 3.40 | 3.40 |
302.29 | 3.56 | 3.56 |
358.38 | 2.13 | 2.13 |
434.45 | 3.43 | 3.43 |
362.42 | 3.15 | 3.15 |
297.31 | 1.87 | 1.87 |
398.47 | 3.62 | 3.62 |
350.33 | 3.56 | 3.56 |
317.39 | 0.85 | 0.85 |
305.38 | 3.41 | 3.41 |
431.54 | 4.45 | 4.45 |
417.51 | 4.14 | 4.14 |
418.72 | 1.31 | 1.31 |
409.52 | 4.56 | 4.56 |
356.43 | 3.15 | 3.15 |
532.05 | 3.60 | 3.60 |
369.41 | 2.38 | 2.38 |
493.39 | 4.68 | 4.68 |
338.36 | 4.40 | 4.40 |
327.38 | 3.58 | 3.58 |
862.75 | -1.10 | -1.10 |
377.42 | 2.97 | 2.97 |
862.75 | -1.10 | -1.10 |
364.41 | 2.49 | 2.49 |
403.44 | 4.11 | 4.11 |
353.43 | 4.20 | 4.20 |
394.46 | 3.45 | 3.45 |
354.79 | 3.82 | 3.82 |
313.38 | 3.65 | 3.65 |
374.27 | 1.20 | 1.20 |
435.26 | 3.27 | 3.27 |
240.26 | 2.56 | 2.56 |
523.60 | 3.33 | 3.33 |
501.59 | 5.05 | 5.05 |
359.18 | 3.37 | 3.37 |
302.36 | 2.24 | 2.24 |
402.54 | 6.48 | 6.48 |
392.41 | 3.68 | 3.68 |
349.37 | 2.94 | 2.94 |
241.29 | 2.28 | 2.28 |
410.74 | 4.54 | 4.54 |
396.49 | 4.34 | 4.34 |
315.35 | 3.37 | 3.37 |
435.00 | 4.83 | 4.83 |
383.88 | 0.94 | 0.94 |
443.98 | 3.22 | 3.22 |
494.60 | 4.07 | 4.07 |
267.28 | 2.47 | 2.47 |
410.45 | 1.48 | 1.48 |
427.53 | 3.53 | 3.53 |
350.76 | 4.52 | 4.52 |
396.49 | 4.17 | 4.17 |
262.27 | 2.65 | 2.65 |
374.19 | 3.90 | 3.90 |
316.31 | 0.62 | 0.62 |
363.39 | 3.33 | 3.33 |
523.46 | 4.23 | 4.23 |
540.67 | 4.09 | 4.09 |
447.39 | 5.07 | 5.07 |
438.53 | 3.86 | 3.86 |
381.53 | 5.15 | 5.15 |
360.37 | 2.01 | 2.01 |
331.47 | 4.08 | 4.08 |
280.41 | 2.78 | 2.78 |
530.37 | 3.48 | 3.48 |
263.30 | 2.58 | 2.58 |
316.31 | 2.25 | 2.25 |
498.61 | 5.19 | 5.19 |
243.26 | 1.13 | 1.13 |
414.59 | 4.49 | 4.49 |
319.74 | 3.40 | 3.40 |
514.33 | 4.56 | 4.56 |
302.79 | 3.94 | 3.94 |
356.38 | 3.52 | 3.52 |
426.37 | 4.17 | 4.17 |
383.43 | 2.77 | 2.77 |
419.48 | 3.53 | 3.53 |
348.32 | 2.40 | 2.40 |
371.42 | 3.48 | 3.48 |
332.31 | 3.57 | 3.57 |
316.31 | 3.87 | 3.87 |
312.76 | 3.88 | 3.88 |
456.55 | 4.01 | 4.01 |
584.70 | 2.88 | 2.88 |
350.37 | 3.18 | 3.18 |
545.27 | 4.26 | 4.26 |
327.43 | 3.71 | 3.71 |
371.78 | 4.11 | 4.11 |
323.39 | 3.92 | 3.92 |
386.27 | 2.55 | 2.55 |
323.44 | 4.32 | 4.32 |
322.15 | 4.57 | 4.57 |
370.50 | 2.74 | 2.74 |
329.38 | 3.35 | 3.35 |
333.44 | 3.10 | 3.10 |
451.53 | 4.61 | 4.61 |
394.38 | 2.53 | 2.53 |
368.51 | 3.13 | 3.13 |
365.01 | 4.22 | 4.22 |
376.41 | 1.58 | 1.58 |
331.80 | 3.70 | 3.70 |
484.58 | 4.88 | 4.88 |
353.85 | 5.16 | 5.16 |
457.58 | 3.13 | 3.13 |
440.51 | 4.97 | 4.97 |
362.35 | 2.70 | 2.70 |
382.45 | 3.29 | 3.29 |
415.88 | 4.57 | 4.57 |
473.92 | 4.11 | 4.11 |
330.34 | 4.17 | 4.17 |
338.32 | 2.91 | 2.91 |
400.48 | 3.00 | 3.00 |
367.88 | 1.10 | 1.10 |
321.33 | 3.08 | 3.08 |
277.75 | 3.52 | 3.52 |
228.25 | 2.22 | 2.22 |
313.31 | 4.83 | 4.83 |
355.44 | 4.83 | 4.83 |
423.90 | 4.18 | 4.18 |
224.30 | 1.22 | 1.22 |
339.40 | 4.01 | 4.01 |
325.39 | 3.77 | 3.77 |
415.23 | 2.90 | 2.90 |
343.43 | 4.78 | 4.78 |
539.66 | 4.75 | 4.75 |
291.78 | 3.91 | 3.91 |
431.45 | 4.30 | 4.30 |
179.20 | 1.99 | 1.99 |
348.32 | 2.40 | 2.40 |
338.33 | 3.31 | 3.31 |
362.35 | 2.70 | 2.70 |
319.74 | 2.31 | 2.31 |
270.29 | 1.74 | 1.74 |
436.42 | 4.26 | 4.26 |
424.20 | 3.08 | 3.08 |
469.56 | 2.55 | 2.55 |
277.28 | 3.26 | 3.26 |
350.41 | 2.41 | 2.41 |
364.78 | 3.60 | 3.60 |
505.00 | 5.23 | 5.23 |
308.34 | 2.74 | 2.74 |
250.21 | -0.24 | -0.24 |
284.70 | 3.60 | 3.60 |
506.97 | 5.43 | 5.43 |
315.35 | 2.67 | 2.67 |
274.24 | 1.85 | 1.85 |
277.71 | 2.43 | 2.43 |
198.17 | 0.17 | 0.17 |
424.53 | 5.16 | 5.16 |
286.37 | 4.49 | 4.49 |
317.35 | 2.55 | 2.55 |
313.36 | 3.45 | 3.45 |
237.26 | 2.57 | 2.57 |
323.42 | 3.94 | 3.94 |
268.07 | 1.71 | 1.71 |
351.20 | 3.43 | 3.43 |
296.17 | 4.83 | 4.83 |
277.28 | 2.38 | 2.38 |
300.31 | 3.74 | 3.74 |
273.29 | 2.50 | 2.50 |
438.53 | 3.98 | 3.98 |
311.77 | 3.35 | 3.35 |
268.32 | 3.19 | 3.19 |
323.29 | 2.82 | 2.82 |
455.54 | 2.71 | 2.71 |
454.57 | 4.92 | 4.92 |
255.23 | 1.12 | 1.12 |
326.37 | 3.47 | 3.47 |
316.27 | 1.04 | 1.04 |
315.35 | 3.54 | 3.54 |
305.76 | 2.63 | 2.63 |
253.06 | 1.03 | 1.03 |
1486.09 | ||
304.37 | 3.81 | 3.81 |
396.83 | 5.31 | 5.31 |
410.48 | 3.16 | 3.16 |
460.51 | 4.37 | 4.37 |
446.48 | 4.06 | 4.06 |
390.86 | 4.30 | 4.30 |
451.53 | 4.08 | 4.08 |
432.46 | 3.76 | 3.76 |
446.48 | 4.06 | 4.06 |
410.48 | 3.82 | 3.82 |
450.45 | 3.89 | 3.89 |
879.86 | 6.39 | 6.39 |
394.48 | 4.12 | 4.12 |
460.51 | 4.32 | 4.32 |
388.41 | -0.33 | -0.33 |
291.31 | 3.99 | 3.99 |
293.28 | 2.60 | 2.60 |
460.51 | 4.32 | 4.32 |
452.51 | 3.91 | 3.91 |
474.54 | 4.68 | 4.68 |
490.49 | 3.54 | 3.54 |
309.12 | 2.10 | 2.10 |