ID: ALA1738362
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose Response concentration confirmation of uHTS hits from a small molecule activators of human intestinal alkaline phosphatase via a luminescent assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2524, AID2571]
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA1738362
EC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
233.27 | 3.21 | 3.21 |
442.47 | 1.00 | 1.00 |
262.32 | 3.96 | 3.96 |
293.71 | -1.76 | -1.76 |
332.16 | 2.56 | 2.56 |
271.29 | 3.65 | 3.65 |
369.45 | 3.31 | 3.31 |
353.49 | 2.62 | 2.62 |
353.45 | 3.41 | 3.41 |
444.54 | 2.43 | 2.43 |
354.23 | 2.35 | 2.35 |
269.39 | 1.54 | 1.54 |
266.69 | 1.78 | 1.78 |
318.53 | 5.47 | 5.47 |
385.44 | 0.76 | 0.76 |
332.86 | 3.98 | 3.98 |
458.34 | 4.76 | 4.76 |
355.35 | 3.30 | 3.30 |
387.49 | 4.08 | 4.08 |
360.35 | 1.25 | 1.25 |
353.38 | 3.36 | 3.36 |
324.34 | 1.71 | 1.71 |
423.29 | 2.63 | 2.63 |
404.43 | 1.78 | 1.78 |
362.28 | 2.21 | 2.21 |
498.63 | 4.32 | 4.32 |
366.47 | 5.32 | 5.32 |
408.34 | 0.68 | 0.68 |
394.46 | 3.94 | 3.94 |
425.83 | 3.04 | 3.04 |
330.82 | 3.38 | 3.38 |
382.45 | 2.63 | 2.63 |
341.44 | 3.41 | 3.41 |
334.34 | 2.47 | 2.47 |
369.32 | 2.75 | 2.75 |
420.35 | 4.37 | 4.37 |
461.95 | 3.10 | 3.10 |
379.53 | 3.27 | 3.27 |
293.32 | 0.13 | 0.13 |
447.96 | 4.40 | 4.40 |
269.31 | 1.73 | 1.73 |
348.37 | 2.78 | 2.78 |
461.53 | 2.71 | 2.71 |
303.36 | 1.84 | 1.84 |
356.29 | 2.89 | 2.89 |
357.48 | 2.78 | 2.78 |
318.53 | 5.23 | 5.23 |
333.34 | 1.48 | 1.48 |
408.34 | 0.68 | 0.68 |
404.54 | 2.89 | 2.89 |
460.51 | 3.23 | 3.23 |
274.24 | 2.44 | 2.44 |
300.34 | 1.03 | 1.03 |
334.38 | 3.18 | 3.18 |
361.81 | 4.24 | 4.24 |
349.44 | 3.35 | 3.35 |
348.24 | 3.99 | 3.99 |
443.53 | 3.12 | 3.12 |
360.24 | 4.35 | 4.35 |
335.36 | 3.32 | 3.32 |
206.27 | 1.33 | 1.33 |
371.51 | 3.51 | 3.51 |
329.40 | 2.84 | 2.84 |
311.30 | 1.58 | 1.58 |
293.33 | 4.65 | 4.65 |
262.34 | 1.26 | 1.26 |
347.42 | 1.80 | 1.80 |
338.30 | 2.30 | 2.30 |
293.33 | 2.38 | 2.38 |
383.46 | 1.97 | 1.97 |
450.56 | 4.83 | 4.83 |
297.45 | 2.91 | 2.91 |
432.57 | 4.69 | 4.69 |
338.21 | 2.23 | 2.23 |
293.41 | 3.27 | 3.27 |
302.33 | 1.17 | 1.17 |
293.33 | 2.67 | 2.67 |
434.56 | 5.18 | 5.18 |
327.40 | -0.19 | -0.19 |
501.60 | 1.75 | 1.75 |
246.27 | 0.85 | 0.85 |
380.50 | 5.63 | 5.63 |
334.44 | 3.11 | 3.11 |
351.36 | 2.75 | 2.75 |
395.47 | 2.07 | 2.07 |
489.94 | 2.95 | 2.95 |
436.99 | 5.64 | 5.64 |
246.27 | 1.84 | 1.84 |
352.45 | 4.70 | 4.70 |
445.45 | 0.85 | 0.85 |
446.60 | 5.00 | 5.00 |
341.40 | 2.39 | 2.39 |
350.43 | -1.23 | -1.23 |
304.35 | 2.73 | 2.73 |
382.43 | 2.30 | 2.30 |
416.57 | 4.99 | 4.99 |
330.29 | 2.48 | 2.48 |
427.55 | 4.05 | 4.05 |
337.84 | 2.10 | 2.10 |
378.48 | 2.74 | 2.74 |
425.47 | 2.58 | 2.58 |
309.37 | 3.13 | 3.13 |
280.45 | 3.75 | 3.75 |
513.67 | 1.15 | 1.15 |
365.35 | 1.37 | 1.37 |
382.38 | 1.03 | 1.03 |
432.57 | 4.69 | 4.69 |
301.43 | 2.16 | 2.16 |
517.63 | 0.98 | 0.98 |
484.37 | 1.96 | 1.96 |
274.75 | 4.00 | 4.00 |
325.33 | 2.14 | 2.14 |
359.18 | 2.79 | 2.79 |
350.33 | 2.27 | 2.27 |
1306.78 | ||
353.18 | 2.04 | 2.04 |
323.15 | 1.95 | 1.95 |
276.30 | 2.71 | 2.71 |
334.34 | 2.44 | 2.44 |
329.43 | 2.44 | 2.44 |
358.31 | 0.11 | 0.11 |
359.77 | 2.47 | 2.47 |
378.35 | 1.16 | 1.16 |
346.35 | 2.94 | 2.94 |
342.44 | 3.70 | 3.70 |
337.30 | 2.01 | 2.01 |
409.39 | 4.52 | 4.52 |
428.45 | 3.33 | 3.33 |
338.37 | 2.54 | 2.54 |
290.28 | -0.03 | -0.03 |
310.31 | 2.45 | 2.45 |
266.31 | 2.31 | 2.31 |
427.47 | 1.67 | 1.67 |
334.38 | -0.32 | -0.32 |
306.73 | 2.84 | 2.84 |
374.35 | 2.19 | 2.19 |
343.35 | 2.65 | 2.65 |
350.40 | 2.02 | 2.02 |
414.42 | 1.50 | 1.50 |
276.25 | -0.33 | -0.33 |