Assay Report Card

Basic Information

ID: ALA1738394

Type: Functional

Description: PUBCHEM_BIOASSAY: Confirmation Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485290, AID485312, AID504464, AID504474]

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
302.191.311.31
375.401.981.98
108.100.250.25
422.352.452.45
562.677.507.50
246.314.494.49
1297.30
390.420.530.53
206.332.792.79
170.120.500.50
1429.19
418.430.590.59
308.312.762.76
448.441.651.65
477.46-0.62-0.62
364.361.791.79
362.09
213.19-0.24-0.24
212.211.311.31
1162.89
412.536.686.68
134.131.311.31
361.535.335.33
415.50-0.32-0.32
472.362.232.23
388.281.201.20
386.312.322.32
332.442.772.77
311.382.862.86
213.242.442.44
444.453.023.02
197.190.050.05
215.252.792.79
215.252.792.79
152.180.640.64
169.180.090.09
372.292.012.01
233.292.662.66
389.805.245.24
219.332.002.00
313.272.122.12
297.362.352.35
476.514.944.94
461.504.164.16
475.534.474.47
229.282.852.85
319.862.502.50
306.271.251.25
186.211.341.34
440.415.185.18
124.230.210.21
193.251.311.31
246.263.173.17
375.420.260.26
418.430.590.59
265.290.770.77
320.055.935.93
408.804.404.40
278.262.852.85
357.16
222.272.232.23
210.191.521.52
262.272.812.81
299.724.314.31
338.587.677.67
310.394.454.45
445.450.480.48
1031.00
1505.11
168.151.221.22
599.311.431.43
466.480.420.42
461.212.632.63
356.382.732.73
420.404.194.19
422.824.394.39
335.434.574.57
438.584.684.68
294.691.801.80
178.232.742.74
310.402.142.14
306.363.443.44
299.291.281.28
386.513.273.27
319.382.912.91
270.292.622.62
400.844.434.43
329.413.613.61
268.272.282.28
255.072.892.89
308.433.103.10
263.262.612.61
380.854.854.85
331.383.913.91
320.31-1.89-1.89
862.75-1.10-1.10
502.523.913.91
376.585.515.51
453.46-0.54-0.54
279.352.392.39
378.411.731.73
671.626.116.11
296.283.093.09
294.291.561.56
333.372.222.22
445.450.480.48
366.234.554.55
277.713.263.26
380.314.224.22
368.244.974.97
390.353.033.03
337.363.393.39
389.533.803.80
260.251.471.47
252.660.830.83
329.311.881.88
434.573.153.15
516.544.154.15
282.252.752.75
365.393.663.66
339.351.521.52
304.25-1.60-1.60
346.34-0.06-0.06
575.665.895.89
224.240.410.41
399.384.874.87
344.373.973.97
239.180.170.17
834.813.863.86
381.844.184.18
289.741.821.82
335.773.623.62
229.722.172.17
321.383.403.40
286.331.261.26
336.74
879.16
366.453.503.50
209.271.281.28
360.374.434.43
203.21-0.28-0.28
469.525.275.27
495.635.445.44
286.292.202.20
346.392.092.09
461.574.604.60
178.192.172.17
271.240.120.12
351.214.034.03
338.393.753.75
341.393.533.53
310.743.443.44
442.574.134.13
392.441.981.98
318.133.673.67
406.515.275.27
407.813.933.93
396.414.474.47
444.453.023.02
398.383.893.89
394.334.614.61
428.942.682.68
219.201.651.65
322.415.245.24
433.464.864.86
345.36-1.70-1.70
412.412.552.55
333.330.830.83
388.462.772.77
388.871.811.81
376.373.883.88
280.333.383.38
341.392.482.48
295.433.513.51
339.151.911.91
362.864.714.71
515.350.440.44
286.343.793.79
407.343.113.11
484.50-0.23-0.23
368.351.811.81
250.712.652.65
453.553.473.47
455.064.304.30
183.121.291.29
314.823.953.95
290.373.723.72
349.382.432.43
492.39-1.19-1.19
322.282.742.74
563.664.154.15
248.88
345.363.063.06
261.92
443.420.010.01
468.293.573.57
353.362.902.90
378.393.653.65
427.532.872.87
470.534.454.45
262.332.322.32
349.841.591.59
338.393.983.98
462.484.234.23
457.275.045.04
433.902.752.75
404.221.681.68
484.604.284.28
422.444.554.55
283.372.242.24
295.342.422.42
401.454.054.05
462.484.634.63
284.233.053.05
412.852.382.38
390.232.872.87
246.292.872.87
347.432.882.88
277.351.891.89
233.181.681.68
376.463.023.02
250.290.340.34
515.623.013.01
405.405.465.46
417.453.753.75
394.393.303.30
309.413.203.20
452.473.183.18
415.453.923.92
428.472.052.05
389.485.235.23
371.422.192.19
390.353.413.41
338.214.104.10
363.02
499.555.285.28
139.150.280.28
433.903.363.36
387.444.674.67
284.362.322.32
281.322.982.98
336.802.942.94
392.894.724.72
519.57-0.71-0.71
348.341.641.64
504.055.335.33
439.523.163.16
300.793.563.56
323.352.432.43
496.47-1.24-1.24
425.314.964.96
264.312.262.26
230.272.322.32
598.563.793.79
422.824.074.07
466.562.902.90
346.393.363.36
378.453.623.62
230.272.322.32
244.154.204.20
408.214.394.39
208.170.250.25
404.494.674.67
409.352.622.62
348.333.603.60
473.103.733.73
397.44-0.99-0.99
366.372.852.85
317.354.044.04
249.231.221.22
291.394.414.41
285.342.222.22
346.442.562.56
404.454.254.25
245.282.292.29
258.282.422.42
308.363.823.82
652.60-1.20-1.20
283.313.123.12
370.793.573.57
374.423.593.59
277.351.861.86
215.262.192.19
271.322.242.24
598.56-1.20-1.20
398.423.973.97
446.37-0.54-0.54
334.432.922.92
345.333.873.87
394.393.303.30
372.502.102.10
304.425.105.10
407.813.933.93
450.834.274.27
367.453.213.21
461.273.313.31
358.431.831.83
376.753.523.52
283.282.552.55
278.313.393.39
444.453.023.02
242.281.961.96
245.271.151.15
413.430.350.35
222.263.033.03
254.353.533.53
425.513.263.26
477.46-0.62-0.62
295.324.034.03
545.605.345.34
337.384.004.00
348.453.353.35
255.282.972.97
380.865.565.56
511.381.431.43
223.231.271.27
387.534.204.20
318.241.691.69
570.463.013.01
489.604.234.23
315.304.914.91
329.36-0.70-0.70
369.484.014.01
419.192.042.04
527.570.470.47
298.392.202.20
461.473.583.58
408.401.791.79
216.192.462.46
322.415.245.24
402.884.954.95
301.333.063.06
321.301.741.74
243.262.892.89
332.444.624.62
350.402.092.09
443.245.055.05
257.252.632.63
458.52-1.22-1.22
259.333.283.28
451.573.883.88
294.384.704.70
476.514.944.94
447.06
402.902.202.20
391.462.772.77
397.315.365.36
411.443.613.61
433.464.864.86
315.343.043.04
380.384.064.06
491.573.623.62
378.392.882.88
330.343.023.02
443.283.743.74
414.522.412.41
400.494.074.07
426.564.024.02
288.693.483.48
375.381.021.02
446.373.043.04
363.373.403.40
453.455.795.79
405.393.413.41
317.733.063.06
309.282.722.72
534.424.244.24
351.794.194.19
324.432.532.53
415.471.751.75
299.332.192.19
250.281.411.41
270.313.243.24
323.383.203.20
314.321.811.81
319.363.173.17
496.573.993.99
351.772.722.72
231.233.073.07
378.435.125.12
316.344.574.57
419.463.673.67
554.54-0.90-0.90
636.66-1.30-1.30
454.964.104.10
478.890.440.44
496.90-1.24-1.24
405.862.652.65
338.443.523.52
388.384.054.05
485.512.142.14
349.393.263.26
493.423.883.88
338.340.400.40
412.351.841.84
447.523.593.59
267.283.813.81
341.424.174.17
388.312.992.99
403.503.663.66
347.392.872.87
184.221.581.58
511.381.431.43
694.372.492.49
223.241.721.72
313.402.262.26
410.43-0.05-0.05
441.474.954.95
286.333.913.91
450.834.804.80
361.313.043.04
475.552.882.88
267.282.362.36
428.942.732.73
256.303.033.03
300.230.250.25
338.392.232.23
341.153.183.18
513.595.635.63
423.435.605.60
371.373.293.29
492.363.033.03
378.393.923.92
341.441.811.81
438.463.303.30
355.422.702.70
285.342.972.97
191.191.501.50
316.324.544.54
368.163.383.38
225.253.273.27
308.373.363.36
212.632.982.98
265.291.811.81
339.352.012.01
496.952.882.88
442.471.431.43
466.833.553.55
488.305.065.06
374.703.543.54
354.392.852.85
444.44-0.21-0.21
608.55-1.09-1.09
349.464.594.59
461.543.613.61
465.584.164.16
527.570.470.47
280.333.483.48
419.555.105.10
430.421.071.07
302.362.082.08
368.513.133.13
282.303.453.45
349.332.892.89
375.383.753.75
445.483.053.05
515.615.885.88
397.412.692.69
451.455.005.00
337.89
416.434.354.35
347.391.901.90
402.414.054.05
347.403.643.64
231.251.931.93
302.314.174.17
359.412.872.87
372.403.343.34
320.362.532.53
396.313.243.24
292.343.163.16
351.38-0.44-0.44
387.442.422.42
363.374.664.66
421.483.653.65
408.803.763.76
450.933.373.37
542.593.913.91
328.825.355.35
331.713.613.61
322.323.513.51
288.100.870.87
314.182.662.66
307.142.932.93
339.381.101.10
359.402.092.09
441.512.632.63
451.503.913.91
340.411.461.46
444.453.023.02
299.332.492.49
484.95-0.10-0.10
295.773.303.30
303.311.921.92
188.610.550.55
393.361.981.98
333.402.632.63
406.412.672.67
450.992.612.61
401.965.575.57
350.333.433.43
236.282.642.64
324.312.712.71
437.41-1.13-1.13
378.392.702.70
211.18-1.86-1.86
460.44-2.50-2.50
309.341.861.86
465.512.922.92
177.161.601.60
289.321.591.59
284.271.621.62
342.761.741.74
279.343.683.68
190.11-0.21-0.21
215.99
336.395.155.15
408.894.144.14
421.453.253.25
267.333.113.11
405.823.943.94
207.252.552.55
374.352.762.76
465.601.671.67
354.320.950.95
329.313.223.22
355.444.834.83
256.261.861.86
324.466.066.06
383.432.902.90
257.292.912.91
420.543.623.62
267.80
305.721.241.24
270.363.693.69
341.363.303.30
439.543.703.70
306.340.790.79
339.404.014.01
241.251.931.93
304.391.611.61
288.314.234.23
316.324.244.24
500.972.002.00
184.191.691.69
196.200.980.98
416.414.654.65
353.373.443.44
262.262.872.87
288.22-0.04-0.04
220.250.610.61
399.532.072.07
431.454.304.30
305.722.412.41
274.353.143.14
316.363.683.68
179.201.991.99
280.302.262.26
354.410.870.87
449.533.343.34
333.413.353.35
436.491.741.74
522.562.662.66
477.904.114.11
323.153.103.10
374.493.123.12
425.533.603.60
264.283.483.48
448.864.714.71
469.505.145.14
320.311.331.33
301.262.252.25
411.513.493.49
401.453.023.02
554.54-1.89-1.89
449.440.100.10
394.09
497.585.895.89
397.493.193.19
461.914.244.24
243.262.602.60
282.342.642.64
252.291.741.74
427.571.411.41
378.392.702.70
421.361.701.70
271.272.652.65
305.384.074.07
372.453.533.53
382.383.383.38
230.230.120.12
278.170.720.72
275.382.712.71
365.783.403.40
361.344.944.94
275.301.651.65
156.140.810.81
540.291.691.69
236.222.092.09
496.90-1.24-1.24
414.492.252.25
268.222.442.44
391.254.614.61
273.362.912.91
384.843.493.49
462.484.634.63
334.444.764.76
254.363.863.86
341.371.741.74
368.00
341.411.731.73
474.045.215.21
496.374.374.37
245.290.590.59
333.260.780.78
383.793.803.80
303.342.072.07
482.353.983.98
371.403.853.85
277.24-0.04-0.04
394.443.813.81
388.403.423.42
238.240.470.47
366.273.343.34
380.864.164.16
230.221.981.98
471.432.782.78
404.424.204.20
530.615.495.49
453.624.864.86
383.432.742.74
348.363.333.33
452.264.454.45
194.14-3.13-3.13
325.800.430.43
316.110.690.69
361.413.503.50
420.382.982.98
408.413.353.35
382.063.983.98
328.353.213.21
375.215.405.40
425.453.473.47
418.453.183.18
327.382.722.72
357.371.431.43
334.383.613.61
419.464.184.18
424.844.474.47
426.482.732.73
381.342.542.54
314.302.592.59
439.594.554.55
403.242.882.88
308.292.932.93
362.823.803.80
436.853.693.69
205.180.620.62
540.746.786.78