Basic Information
ID: ALA1738394
Type: Functional
Description: PUBCHEM_BIOASSAY: Confirmation Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485290, AID485312, AID504464, AID504474]
Format: BAO_0000019
Organism: Homo sapiens
Target: Tyrosyl-DNA phosphodiesterase 1(ALA1075138)
Document: ALA1201862
PubChem Source: AID:489007
Activity Charts
Bioactivity
Activity Types for Assay ALA1738394
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1297.30 | ||
| 169.18 | 0.09 | 0.09 |
| 476.51 | 4.94 | 4.94 |
| 475.53 | 4.47 | 4.47 |
| 193.25 | 1.31 | 1.31 |
| 265.29 | 0.77 | 0.77 |
| 357.16 | ||
| 168.15 | 1.22 | 1.22 |
| 294.69 | 1.80 | 1.80 |
| 310.40 | 2.14 | 2.14 |
| 299.29 | 1.28 | 1.28 |
| 263.26 | 2.61 | 2.61 |
| 862.75 | -1.10 | -1.10 |
| 453.46 | -0.54 | -0.54 |
| 294.29 | 1.56 | 1.56 |
| 337.36 | 3.39 | 3.39 |
| 389.53 | 3.80 | 3.80 |
| 289.74 | 1.82 | 1.82 |
| 335.77 | 3.62 | 3.62 |
| 879.16 | ||
| 209.27 | 1.28 | 1.28 |
| 461.57 | 4.60 | 4.60 |
| 322.41 | 5.24 | 5.24 |
| 280.33 | 3.38 | 3.38 |
| 341.39 | 2.48 | 2.48 |
| 295.43 | 3.51 | 3.51 |
| 362.86 | 4.71 | 4.71 |
| 286.34 | 3.79 | 3.79 |
| 248.88 | ||
| 404.22 | 1.68 | 1.68 |
| 484.60 | 4.28 | 4.28 |
| 462.48 | 4.63 | 4.63 |
| 347.43 | 2.88 | 2.88 |
| 309.41 | 3.20 | 3.20 |
| 139.15 | 0.28 | 0.28 |
| 336.80 | 2.94 | 2.94 |
| 504.05 | 5.33 | 5.33 |
| 425.31 | 4.96 | 4.96 |
| 422.82 | 4.07 | 4.07 |
| 230.27 | 2.32 | 2.32 |
| 473.10 | 3.73 | 3.73 |
| 291.39 | 4.41 | 4.41 |
| 285.34 | 2.22 | 2.22 |
| 404.45 | 4.25 | 4.25 |
| 398.42 | 3.97 | 3.97 |
| 345.33 | 3.87 | 3.87 |
| 304.42 | 5.10 | 5.10 |
| 407.81 | 3.93 | 3.93 |
| 444.45 | 3.02 | 3.02 |
| 242.28 | 1.96 | 1.96 |
| 222.26 | 3.03 | 3.03 |
| 337.38 | 4.00 | 4.00 |
| 348.45 | 3.35 | 3.35 |
| 255.28 | 2.97 | 2.97 |
| 298.39 | 2.20 | 2.20 |
| 321.30 | 1.74 | 1.74 |
| 243.26 | 2.89 | 2.89 |
| 391.46 | 2.77 | 2.77 |
| 315.34 | 3.04 | 3.04 |
| 378.39 | 2.88 | 2.88 |
| 330.34 | 3.02 | 3.02 |
| 288.69 | 3.48 | 3.48 |
| 319.36 | 3.17 | 3.17 |
| 419.46 | 3.67 | 3.67 |
| 554.54 | -0.90 | -0.90 |
| 493.42 | 3.88 | 3.88 |
| 341.42 | 4.17 | 4.17 |
| 184.22 | 1.58 | 1.58 |
| 511.38 | 1.43 | 1.43 |
| 267.28 | 2.36 | 2.36 |
| 285.34 | 2.97 | 2.97 |
| 191.19 | 1.50 | 1.50 |
| 339.35 | 2.01 | 2.01 |
| 374.70 | 3.54 | 3.54 |
| 465.58 | 4.16 | 4.16 |
| 430.42 | 1.07 | 1.07 |
| 372.40 | 3.34 | 3.34 |
| 408.80 | 3.76 | 3.76 |
| 322.32 | 3.51 | 3.51 |
| 336.39 | 5.15 | 5.15 |
| 270.36 | 3.69 | 3.69 |
| 241.25 | 1.93 | 1.93 |
| 196.20 | 0.98 | 0.98 |
| 399.53 | 2.07 | 2.07 |
| 431.45 | 4.30 | 4.30 |
| 449.53 | 3.34 | 3.34 |
| 301.26 | 2.25 | 2.25 |
| 397.49 | 3.19 | 3.19 |
| 230.22 | 1.98 | 1.98 |
| 471.43 | 2.78 | 2.78 |
| 404.42 | 4.20 | 4.20 |
| 453.62 | 4.86 | 4.86 |
| 194.14 | -3.13 | -3.13 |
| 325.80 | 0.43 | 0.43 |
| 361.41 | 3.50 | 3.50 |
| 328.35 | 3.21 | 3.21 |
| 327.38 | 2.72 | 2.72 |
| 424.84 | 4.47 | 4.47 |
| 314.30 | 2.59 | 2.59 |
| 540.74 | 6.78 | 6.78 |