Basic Information
ID: ALA1738395
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS hits from a small molecule inhibitors of mouse intestinal alkaline phosphatase via a luminescent assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2806, AID2818]
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA1738395
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 368.39 | 3.37 | 3.37 |
| 270.24 | 1.37 | 1.37 |
| 297.27 | 2.30 | 2.30 |
| 318.24 | 1.69 | 1.69 |
| 186.17 | 1.53 | 1.53 |
| 492.45 | 5.70 | 5.70 |
| 368.39 | 3.85 | 3.85 |
| 168.15 | 0.72 | 0.72 |
| 287.31 | 1.94 | 1.94 |
| 338.36 | 3.84 | 3.84 |
| 400.36 | 2.93 | 2.93 |
| 397.42 | 1.89 | 1.89 |
| 464.38 | -0.54 | -0.54 |
| 309.37 | 2.51 | 2.51 |
| 270.24 | 2.42 | 2.42 |
| 168.17 | 1.56 | 1.56 |
| 382.40 | 2.93 | 2.93 |
| 290.27 | 1.55 | 1.55 |
| 381.50 | 4.84 | 4.84 |
| 306.30 | 0.77 | 0.77 |
| 308.29 | 1.55 | 1.55 |
| 687.71 | 10.29 | 10.29 |
| 308.29 | 1.55 | 1.55 |
| 437.19 | 3.21 | 3.21 |
| 425.49 | 2.68 | 2.68 |
| 348.34 | 2.12 | 2.12 |
| 448.59 | 5.74 | 5.74 |
| 436.99 | 5.38 | 5.38 |
| 385.45 | 3.36 | 3.36 |
| 265.18 | 0.28 | 0.28 |
| 351.41 | 1.45 | 1.45 |
| 388.46 | -0.50 | -0.50 |
| 338.46 | 3.45 | 3.45 |
| 392.46 | 2.86 | 2.86 |
| 418.45 | 2.91 | 2.91 |
| 472.50 | 3.33 | 3.33 |
| 372.43 | 3.09 | 3.09 |
| 389.43 | 2.46 | 2.46 |
| 366.46 | 5.22 | 5.22 |
| 610.52 | -1.69 | -1.69 |
| 206.18 | -0.87 | -0.87 |
| 291.22 | 1.38 | 1.38 |
| 367.31 | 3.27 | 3.27 |
| 207.27 | 0.05 | 0.05 |
| 293.74 | 2.04 | 2.04 |
| 194.22 | 1.21 | 1.21 |
| 434.56 | 5.26 | 5.26 |
| 327.79 | 3.93 | 3.93 |
| 370.86 | 5.12 | 5.12 |
| 317.29 | 4.29 | 4.29 |
| 343.43 | 3.50 | 3.50 |
| 386.39 | 1.71 | 1.71 |
| 300.31 | 3.12 | 3.12 |
| 451.01 | 5.69 | 5.69 |
| 470.24 | 3.78 | 3.78 |
| 403.57 | 4.07 | 4.07 |
| 462.53 | 3.65 | 3.65 |
| 265.18 | 0.28 | 0.28 |
| 314.48 | 3.89 | 3.89 |
| 282.32 | 1.71 | 1.71 |
| 354.37 | 0.24 | 0.24 |
| 468.29 | 3.57 | 3.57 |
| 380.94 | 5.85 | 5.85 |
| 492.55 | 4.98 | 4.98 |
| 376.46 | 3.08 | 3.08 |
| 279.35 | 4.05 | 4.05 |
| 413.46 | 2.12 | 2.12 |
| 378.80 | 3.10 | 3.10 |
| 427.46 | 2.27 | 2.27 |
| 367.34 | 1.86 | 1.86 |
| 400.54 | 4.16 | 4.16 |
| 357.42 | 2.78 | 2.78 |
| 318.35 | 2.95 | 2.95 |
| 462.53 | 4.97 | 4.97 |
| 365.42 | 2.16 | 2.16 |
| 428.56 | 1.90 | 1.90 |
| 166.18 | 0.96 | 0.96 |
| 372.43 | 2.64 | 2.64 |
| 332.83 | 4.86 | 4.86 |
| 330.36 | 2.24 | 2.24 |
| 393.53 | 4.71 | 4.71 |
| 410.97 | 6.08 | 6.08 |
| 321.38 | 1.40 | 1.40 |
| 349.39 | 0.94 | 0.94 |
| 450.52 | 3.32 | 3.32 |
| 406.55 | 5.62 | 5.62 |
| 419.19 | 2.04 | 2.04 |
| 451.92 | 6.07 | 6.07 |
| 412.49 | 3.67 | 3.67 |
| 368.91 | 5.21 | 5.21 |
| 252.29 | 0.36 | 0.36 |
| 468.52 | 1.91 | 1.91 |
| 405.43 | 1.53 | 1.53 |
| 315.12 | 0.57 | 0.57 |
| 484.60 | 1.98 | 1.98 |
| 441.94 | 4.35 | 4.35 |
| 307.29 | 1.85 | 1.85 |
| 337.31 | 1.61 | 1.61 |
| 421.43 | 1.86 | 1.86 |
| 376.52 | 5.62 | 5.62 |
| 331.33 | 3.19 | 3.19 |
| 414.49 | 3.92 | 3.92 |
| 364.43 | 2.77 | 2.77 |
| 449.00 | 5.55 | 5.55 |
| 380.94 | 5.85 | 5.85 |
| 393.60 | 4.96 | 4.96 |
| 362.44 | 2.77 | 2.77 |
| 444.58 | 5.19 | 5.19 |
| 400.52 | 6.49 | 6.49 |
| 399.63 | 5.65 | 5.65 |
| 316.34 | 2.50 | 2.50 |
| 404.43 | 2.52 | 2.52 |
| 288.25 | 2.22 | 2.22 |
| 318.53 | 4.98 | 4.98 |
| 353.38 | 1.96 | 1.96 |
| 318.38 | 3.72 | 3.72 |
| 381.44 | 2.56 | 2.56 |
| 372.43 | 2.64 | 2.64 |
| 259.29 | 2.35 | 2.35 |
| 544.51 | 4.06 | 4.06 |
| 437.52 | 3.32 | 3.32 |
| 438.96 | 5.60 | 5.60 |
| 380.48 | 5.29 | 5.29 |
| 434.56 | 5.18 | 5.18 |
| 460.51 | 3.69 | 3.69 |
| 262.29 | 1.09 | 1.09 |
| 380.43 | 2.91 | 2.91 |
| 404.43 | 2.52 | 2.52 |
| 317.37 | 2.48 | 2.48 |
| 256.32 | 0.38 | 0.38 |
| 299.36 | 3.67 | 3.67 |
| 459.51 | 2.41 | 2.41 |
| 257.29 | 2.43 | 2.43 |
| 463.36 | 6.42 | 6.42 |
| 323.40 | 2.90 | 2.90 |
| 422.96 | 4.90 | 4.90 |
| 394.97 | 6.38 | 6.38 |
| 432.48 | 3.30 | 3.30 |
| 328.35 | 2.12 | 2.12 |
| 350.43 | -1.23 | -1.23 |
| 316.34 | 2.50 | 2.50 |
| 394.97 | 6.38 | 6.38 |
| 338.33 | 4.60 | 4.60 |
| 414.55 | 6.05 | 6.05 |
| 396.88 | 3.42 | 3.42 |
| 440.43 | 4.84 | 4.84 |
| 465.35 | 4.84 | 4.84 |
| 361.38 | 1.84 | 1.84 |
| 419.46 | 1.92 | 1.92 |
| 395.82 | 2.45 | 2.45 |
| 383.45 | 3.07 | 3.07 |
| 391.41 | 1.80 | 1.80 |
| 405.43 | 1.53 | 1.53 |
| 442.60 | 5.77 | 5.77 |
| 430.52 | 2.05 | 2.05 |
| 368.44 | 2.53 | 2.53 |
| 349.76 | 3.82 | 3.82 |
| 1195.59 | ||
| 464.43 | 1.80 | 1.80 |
| 406.39 | 3.09 | 3.09 |
| 1222.66 | ||
| 1218.65 | ||
| 403.41 | 4.00 | 4.00 |
| 1306.78 | ||
| 525.54 | 2.43 | 2.43 |
| 284.32 | 1.00 | 1.00 |
| 1306.78 | ||
| 315.35 | 2.63 | 2.63 |
| 262.23 | 0.55 | 0.55 |
| 384.23 | 1.75 | 1.75 |
| 273.25 | 0.96 | 0.96 |
| 358.31 | 0.11 | 0.11 |
| 389.41 | 3.44 | 3.44 |
| 332.34 | 2.33 | 2.33 |
| 388.41 | -0.33 | -0.33 |
| 282.35 | 1.59 | 1.59 |
| 436.52 | 1.44 | 1.44 |
| 342.35 | 4.08 | 4.08 |
| 271.25 | -0.28 | -0.28 |
| 401.20 | 1.19 | 1.19 |