ID: ALA1738407
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID782]
Bioactivity
Activity Types for Assay ALA1738407
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
302.19 | 1.31 | 1.31 |
406.91 | 6.61 | 6.61 |
204.18 | 1.42 | 1.42 |
221.26 | 3.61 | 3.61 |
206.33 | 2.79 | 2.79 |
227.29 | 3.05 | 3.05 |
274.18 | ||
518.56 | 6.38 | 6.38 |
258.75 | 3.10 | 3.10 |
228.73 | 3.09 | 3.09 |
318.81 | 3.12 | 3.12 |
239.23 | 1.75 | 1.75 |
458.47 | 3.96 | 3.96 |
258.23 | 2.32 | 2.32 |
316.15 | 4.45 | 4.45 |
214.22 | 2.88 | 2.88 |
460.44 | -1.24 | -1.24 |
337.42 | 3.15 | 3.15 |
436.54 | 3.62 | 3.62 |
186.21 | 1.34 | 1.34 |
252.27 | 3.41 | 3.41 |
412.44 | 3.96 | 3.96 |
296.41 | 4.01 | 4.01 |
362.90 | 5.04 | 5.04 |
252.36 | 3.84 | 3.84 |
282.39 | 3.39 | 3.39 |
561.15 | 5.39 | 5.39 |
424.51 | 3.42 | 3.42 |
379.93 | 3.49 | 3.49 |
321.80 | 2.85 | 2.85 |
365.36 | 1.77 | 1.77 |
370.41 | 4.19 | 4.19 |
355.87 | 2.89 | 2.89 |
400.89 | 4.10 | 4.10 |
321.36 | 4.20 | 4.20 |
454.50 | 5.30 | 5.30 |
217.27 | 1.80 | 1.80 |
509.51 | 4.77 | 4.77 |
438.83 | 2.44 | 2.44 |
487.51 | 5.41 | 5.41 |
463.60 | 4.00 | 4.00 |
287.79 | 4.39 | 4.39 |
303.32 | 3.70 | 3.70 |
273.72 | 2.99 | 2.99 |
258.30 | 2.35 | 2.35 |
439.54 | 3.67 | 3.67 |
346.39 | 3.54 | 3.54 |
471.86 | 6.57 | 6.57 |
429.49 | 5.85 | 5.85 |
259.31 | 3.50 | 3.50 |
441.53 | 3.73 | 3.73 |
337.38 | 4.15 | 4.15 |
243.67 | 3.23 | 3.23 |
288.40 | 2.14 | 2.14 |
335.47 | 2.34 | 2.34 |
331.21 | 2.55 | 2.55 |
235.67 | 2.93 | 2.93 |
406.50 | 5.63 | 5.63 |
339.42 | 3.25 | 3.25 |
428.56 | 3.48 | 3.48 |
478.55 | 2.57 | 2.57 |
371.42 | 1.97 | 1.97 |
428.49 | 3.31 | 3.31 |
369.45 | 3.16 | 3.16 |
462.97 | 2.45 | 2.45 |
366.23 | 4.55 | 4.55 |
363.33 | 3.04 | 3.04 |
317.26 | 2.70 | 2.70 |
294.35 | 2.92 | 2.92 |
493.66 | 4.51 | 4.51 |
380.35 | 3.70 | 3.70 |
284.39 | 3.52 | 3.52 |
485.97 | 5.71 | 5.71 |
265.36 | 2.26 | 2.26 |
320.35 | 2.90 | 2.90 |
311.34 | 1.22 | 1.22 |
297.31 | 1.87 | 1.87 |
490.54 | 5.25 | 5.25 |
250.34 | 1.38 | 1.38 |
351.45 | 2.11 | 2.11 |
220.30 | 1.59 | 1.59 |
237.35 | 3.19 | 3.19 |
287.32 | 2.40 | 2.40 |
341.41 | 3.71 | 3.71 |
402.50 | 4.83 | 4.83 |
360.37 | 4.43 | 4.43 |
268.35 | 2.68 | 2.68 |
337.81 | 4.47 | 4.47 |
360.44 | 1.97 | 1.97 |
469.52 | 5.27 | 5.27 |
336.42 | 2.95 | 2.95 |
241.32 | 3.36 | 3.36 |
445.57 | 2.67 | 2.67 |
443.57 | 3.24 | 3.24 |
334.42 | 2.30 | 2.30 |
488.01 | 6.33 | 6.33 |
310.39 | 2.44 | 2.44 |
337.40 | 4.14 | 4.14 |
417.51 | 4.14 | 4.14 |
390.51 | 2.83 | 2.83 |
396.47 | 4.20 | 4.20 |
409.52 | 4.56 | 4.56 |
252.36 | 2.82 | 2.82 |
407.81 | 3.93 | 3.93 |
391.21 | 3.78 | 3.78 |
320.38 | 1.38 | 1.38 |
338.42 | 3.31 | 3.31 |
363.42 | 3.88 | 3.88 |
329.49 | 2.85 | 2.85 |
438.47 | 2.47 | 2.47 |
435.51 | 6.23 | 6.23 |
382.42 | 4.51 | 4.51 |
264.28 | 1.56 | 1.56 |
330.38 | 2.89 | 2.89 |
410.81 | 3.66 | 3.66 |
329.41 | 4.48 | 4.48 |
222.24 | 1.25 | 1.25 |
366.24 | 4.61 | 4.61 |
377.42 | 2.97 | 2.97 |
460.44 | 4.59 | 4.59 |
250.71 | 2.65 | 2.65 |
478.41 | 4.27 | 4.27 |
378.38 | 1.14 | 1.14 |
448.48 | 2.96 | 2.96 |
267.37 | 2.12 | 2.12 |
404.45 | 3.75 | 3.75 |
238.25 | 2.45 | 2.45 |
245.29 | 3.41 | 3.41 |
290.37 | 3.72 | 3.72 |
315.33 | 2.71 | 2.71 |
408.48 | 4.95 | 4.95 |
350.47 | 2.71 | 2.71 |
364.41 | 2.49 | 2.49 |
328.21 | 2.63 | 2.63 |
436.99 | 6.51 | 6.51 |
441.56 | 4.28 | 4.28 |
491.57 | 2.92 | 2.92 |
488.29 | 4.04 | 4.04 |
515.69 | 4.55 | 4.55 |
431.86 | 2.54 | 2.54 |
487.51 | 5.41 | 5.41 |
298.39 | 3.03 | 3.03 |
461.57 | 1.91 | 1.91 |
363.53 | 2.56 | 2.56 |
307.38 | 2.45 | 2.45 |
378.39 | 3.65 | 3.65 |
260.34 | 3.14 | 3.14 |
235.35 | 2.80 | 2.80 |
229.28 | 2.53 | 2.53 |
302.42 | 4.22 | 4.22 |
308.29 | 2.94 | 2.94 |
273.36 | 2.70 | 2.70 |
303.79 | 2.85 | 2.85 |
377.41 | 2.72 | 2.72 |
401.45 | 4.05 | 4.05 |
462.48 | 4.63 | 4.63 |
315.35 | 2.81 | 2.81 |
483.58 | 6.94 | 6.94 |
298.39 | 4.64 | 4.64 |
270.29 | 2.05 | 2.05 |
313.31 | 2.12 | 2.12 |
352.91 | 4.65 | 4.65 |
288.24 | 2.95 | 2.95 |
417.45 | 3.75 | 3.75 |
377.26 | 4.74 | 4.74 |
375.43 | 3.13 | 3.13 |
402.47 | 4.99 | 4.99 |
368.37 | 2.68 | 2.68 |
234.31 | 2.51 | 2.51 |
387.44 | 4.53 | 4.53 |
277.32 | 1.24 | 1.24 |
333.43 | 3.43 | 3.43 |
356.23 | 3.58 | 3.58 |
431.32 | 5.34 | 5.34 |
266.30 | 2.75 | 2.75 |
208.17 | 0.25 | 0.25 |
378.45 | 5.45 | 5.45 |
409.87 | 4.52 | 4.52 |
373.61 | 5.58 | 5.58 |
403.42 | 1.45 | 1.45 |
393.58 | 5.51 | 5.51 |
404.49 | 4.67 | 4.67 |
350.42 | 4.45 | 4.45 |
402.41 | 3.58 | 3.58 |
350.20 | 4.60 | 4.60 |
284.40 | 4.12 | 4.12 |
393.52 | 4.46 | 4.46 |
407.49 | 2.63 | 2.63 |
292.36 | 2.97 | 2.97 |
415.45 | 4.60 | 4.60 |
364.36 | 3.26 | 3.26 |
381.48 | 3.82 | 3.82 |
267.28 | 2.47 | 2.47 |
495.00 | 5.97 | 5.97 |
441.38 | 2.93 | 2.93 |
322.32 | 2.77 | 2.77 |
330.34 | 3.67 | 3.67 |
363.44 | 5.12 | 5.12 |
427.89 | 2.52 | 2.52 |
412.29 | 3.64 | 3.64 |
398.47 | 3.18 | 3.18 |
261.32 | 1.86 | 1.86 |
388.51 | 3.54 | 3.54 |
374.47 | 2.70 | 2.70 |
291.31 | 3.45 | 3.45 |
321.38 | 3.76 | 3.76 |
407.81 | 3.93 | 3.93 |
295.29 | 2.91 | 2.91 |
451.53 | 4.08 | 4.08 |
309.76 | 4.42 | 4.42 |
383.50 | 3.98 | 3.98 |
329.79 | 3.66 | 3.66 |
365.46 | 3.49 | 3.49 |
444.45 | 3.02 | 3.02 |
280.28 | 1.94 | 1.94 |
465.56 | 3.91 | 3.91 |
433.58 | 1.53 | 1.53 |
310.69 | 2.49 | 2.49 |
447.54 | 3.26 | 3.26 |
420.83 | 4.20 | 4.20 |
262.27 | 2.65 | 2.65 |
341.39 | 2.92 | 2.92 |
212.72 | 2.18 | 2.18 |
354.50 | 4.85 | 4.85 |
436.42 | 3.42 | 3.42 |
585.16 | 5.38 | 5.38 |
476.41 | 4.20 | 4.20 |
481.51 | 7.61 | 7.61 |
345.45 | 3.38 | 3.38 |
244.27 | 2.19 | 2.19 |
406.80 | 4.20 | 4.20 |
509.48 | ||
382.42 | 2.66 | 2.66 |
243.31 | 2.84 | 2.84 |
377.36 | 3.35 | 3.35 |
371.39 | 3.06 | 3.06 |
387.45 | 5.79 | 5.79 |
375.48 | 3.39 | 3.39 |
295.30 | 2.34 | 2.34 |
267.35 | 1.80 | 1.80 |
272.14 | 3.05 | 3.05 |
427.47 | 5.55 | 5.55 |
350.46 | 2.40 | 2.40 |
288.35 | 4.36 | 4.36 |
316.31 | 2.25 | 2.25 |
338.43 | 2.55 | 2.55 |
365.39 | 3.82 | 3.82 |
327.45 | 4.39 | 4.39 |
396.51 | 4.39 | 4.39 |
437.48 | 3.79 | 3.79 |
247.32 | 2.34 | 2.34 |
309.33 | 2.18 | 2.18 |
288.69 | 3.48 | 3.48 |
369.49 | 2.70 | 2.70 |
392.48 | 4.75 | 4.75 |
292.39 | 1.90 | 1.90 |
448.57 | 3.56 | 3.56 |
525.97 | 6.24 | 6.24 |
346.39 | 2.97 | 2.97 |
376.25 | 4.07 | 4.07 |
293.16 | 3.70 | 3.70 |
209.18 | 1.40 | 1.40 |
315.15 | 3.36 | 3.36 |
426.37 | 4.17 | 4.17 |
419.53 | 3.27 | 3.27 |
593.70 | 3.94 | 3.94 |
544.70 | 4.87 | 4.87 |
342.46 | 3.15 | 3.15 |
633.44 | -0.53 | -0.53 |
342.87 | 4.64 | 4.64 |
326.74 | 3.11 | 3.11 |
388.50 | 1.93 | 1.93 |
337.83 | 2.57 | 2.57 |
497.65 | 6.45 | 6.45 |
351.41 | 3.55 | 3.55 |
238.33 | 3.45 | 3.45 |
354.36 | 2.15 | 2.15 |
362.67 | 3.70 | 3.70 |
305.34 | 2.57 | 2.57 |
257.77 | 3.07 | 3.07 |
319.43 | 5.08 | 5.08 |
401.54 | 4.91 | 4.91 |
336.39 | 3.53 | 3.53 |
361.20 | 4.18 | 4.18 |
225.33 | 2.25 | 2.25 |
365.22 | 4.14 | 4.14 |
235.31 | 1.90 | 1.90 |
199.64 | 1.44 | 1.44 |
441.47 | 4.95 | 4.95 |
275.40 | 2.41 | 2.41 |
290.32 | 3.64 | 3.64 |
411.46 | 5.27 | 5.27 |
303.11 | 3.50 | 3.50 |
382.45 | 3.74 | 3.74 |
323.47 | 2.94 | 2.94 |
320.35 | 4.10 | 4.10 |
372.45 | 3.47 | 3.47 |
427.47 | 6.26 | 6.26 |
423.43 | 5.60 | 5.60 |
378.39 | 3.92 | 3.92 |
336.39 | 3.78 | 3.78 |
332.36 | 3.20 | 3.20 |
527.57 | 0.47 | 0.47 |
321.34 | 3.35 | 3.35 |
395.89 | 2.82 | 2.82 |
271.34 | 2.83 | 2.83 |
396.45 | 1.70 | 1.70 |
264.71 | 3.70 | 3.70 |
288.35 | 1.37 | 1.37 |
544.70 | 4.87 | 4.87 |
378.37 | 2.06 | 2.06 |
276.32 | 3.15 | 3.15 |
275.36 | 4.32 | 4.32 |
422.49 | 4.08 | 4.08 |
388.45 | 3.28 | 3.28 |
206.21 | 1.09 | 1.09 |
282.34 | 2.51 | 2.51 |
347.27 | 3.53 | 3.53 |
342.78 | 3.13 | 3.13 |
316.45 | 1.82 | 1.82 |
559.08 | 6.09 | 6.09 |
341.42 | 4.57 | 4.57 |
368.51 | 3.13 | 3.13 |
437.56 | 1.34 | 1.34 |
342.45 | 3.18 | 3.18 |
282.30 | 3.45 | 3.45 |
349.70 | 2.02 | 2.02 |
500.29 | 2.73 | 2.73 |
466.59 | 4.41 | 4.41 |
304.80 | 4.69 | 4.69 |
320.37 | 3.79 | 3.79 |
252.28 | 2.35 | 2.35 |
372.28 | 2.86 | 2.86 |
288.35 | 0.89 | 0.89 |
323.39 | 3.88 | 3.88 |
454.96 | 4.73 | 4.73 |
460.49 | 4.96 | 4.96 |
448.98 | 2.48 | 2.48 |
231.25 | 1.93 | 1.93 |
267.38 | 2.78 | 2.78 |
371.55 | 2.27 | 2.27 |
245.28 | 2.23 | 2.23 |
220.31 | -1.06 | -1.06 |
352.39 | 3.52 | 3.52 |
312.35 | 3.53 | 3.53 |
400.42 | 4.46 | 4.46 |
273.38 | 1.53 | 1.53 |
353.85 | 5.16 | 5.16 |
366.45 | 2.90 | 2.90 |
519.64 | 5.09 | 5.09 |
411.47 | 3.16 | 3.16 |
490.54 | 5.25 | 5.25 |
542.59 | 3.91 | 3.91 |
544.70 | 4.87 | 4.87 |
408.46 | 3.61 | 3.61 |
537.61 | 6.16 | 6.16 |
210.28 | 1.68 | 1.68 |
474.65 | 3.91 | 3.91 |
428.50 | 3.62 | 3.62 |
318.38 | 2.17 | 2.17 |
356.81 | 2.69 | 2.69 |
379.44 | 3.56 | 3.56 |
440.33 | 5.11 | 5.11 |
472.50 | 3.63 | 3.63 |
351.86 | 3.13 | 3.13 |
340.34 | 2.92 | 2.92 |
650.19 | 5.38 | 5.38 |
288.37 | 2.41 | 2.41 |
299.33 | 2.49 | 2.49 |
403.43 | 4.09 | 4.09 |
518.01 | 3.60 | 3.60 |
455.94 | 5.70 | 5.70 |
407.25 | 1.33 | 1.33 |
196.21 | 1.82 | 1.82 |
188.61 | 0.55 | 0.55 |
288.38 | 2.50 | 2.50 |
308.38 | 2.85 | 2.85 |
361.39 | 1.88 | 1.88 |
387.53 | 4.24 | 4.24 |
422.48 | 0.73 | 0.73 |
467.91 | 2.61 | 2.61 |
448.52 | 5.27 | 5.27 |
361.44 | 4.57 | 4.57 |
382.51 | 2.97 | 2.97 |
207.26 | 2.01 | 2.01 |
387.44 | 2.95 | 2.95 |
207.26 | 2.01 | 2.01 |
355.44 | 4.83 | 4.83 |
289.29 | 1.68 | 1.68 |
423.87 | 4.31 | 4.31 |
339.36 | 2.28 | 2.28 |
291.87 | 3.79 | 3.79 |
394.26 | 3.48 | 3.48 |
380.44 | 1.38 | 1.38 |
538.74 | 5.30 | 5.30 |
404.43 | 3.74 | 3.74 |
316.18 | 3.13 | 3.13 |
285.73 | 3.04 | 3.04 |
340.47 | 4.64 | 4.64 |
392.46 | 3.20 | 3.20 |
257.29 | 2.43 | 2.43 |
339.40 | 4.01 | 4.01 |
288.31 | 4.23 | 4.23 |
408.80 | 3.76 | 3.76 |
154.17 | -0.01 | -0.01 |
354.41 | 2.92 | 2.92 |
238.34 | 2.43 | 2.43 |
361.42 | 3.05 | 3.05 |
230.22 | 2.51 | 2.51 |
404.49 | 2.63 | 2.63 |
476.92 | 3.19 | 3.19 |
275.35 | 3.26 | 3.26 |
365.37 | 4.05 | 4.05 |
169.21 | 1.26 | 1.26 |
450.32 | 5.67 | 5.67 |
337.36 | 3.47 | 3.47 |
288.22 | -0.04 | -0.04 |
343.43 | 4.78 | 4.78 |
274.32 | 3.04 | 3.04 |
380.90 | 3.00 | 3.00 |
435.46 | 2.66 | 2.66 |
354.46 | 3.18 | 3.18 |
427.44 | 3.59 | 3.59 |
287.34 | 3.21 | 3.21 |
295.34 | 4.02 | 4.02 |
255.73 | 2.60 | 2.60 |
305.34 | 1.01 | 1.01 |
298.34 | 3.37 | 3.37 |
409.42 | 2.99 | 2.99 |
317.43 | 3.50 | 3.50 |
372.41 | 3.07 | 3.07 |
329.36 | 1.31 | 1.31 |
367.50 | 4.37 | 4.37 |
311.38 | 2.05 | 2.05 |
226.30 | 0.68 | 0.68 |
334.40 | 2.20 | 2.20 |
418.52 | 2.42 | 2.42 |
432.47 | 1.99 | 1.99 |
396.47 | 3.31 | 3.31 |
445.50 | 2.85 | 2.85 |
280.33 | 2.28 | 2.28 |
269.26 | 2.24 | 2.24 |
439.51 | 2.84 | 2.84 |
351.45 | 4.20 | 4.20 |
404.29 | 4.45 | 4.45 |
401.46 | 2.75 | 2.75 |
344.44 | 4.49 | 4.49 |
360.89 | 4.96 | 4.96 |
457.88 | 3.26 | 3.26 |
362.30 | 3.44 | 3.44 |
366.45 | 3.36 | 3.36 |
296.40 | 4.07 | 4.07 |
259.27 | 1.33 | 1.33 |
336.39 | 3.59 | 3.59 |
375.45 | 4.37 | 4.37 |
396.18 | 3.63 | 3.63 |
278.37 | 2.52 | 2.52 |
422.82 | 3.82 | 3.82 |
328.37 | 3.26 | 3.26 |
478.46 | 6.02 | 6.02 |
361.19 | 3.19 | 3.19 |
248.11 | 1.64 | 1.64 |
406.80 | 4.20 | 4.20 |
435.32 | 2.95 | 2.95 |
300.41 | 1.58 | 1.58 |
454.24 | 3.64 | 3.64 |
307.63 | 3.85 | 3.85 |
257.36 | 3.97 | 3.97 |
248.26 | 2.09 | 2.09 |
291.38 | 2.85 | 2.85 |
263.17 | 3.74 | 3.74 |
312.77 | 2.15 | 2.15 |
323.23 | 3.76 | 3.76 |
359.34 | 4.84 | 4.84 |
328.76 | 3.68 | 3.68 |
402.50 | 3.16 | 3.16 |
382.38 | 2.58 | 2.58 |
295.30 | 1.53 | 1.53 |
278.31 | 4.43 | 4.43 |
242.76 | 3.40 | 3.40 |
413.91 | 4.42 | 4.42 |
448.52 | 1.87 | 1.87 |
334.53 | 3.87 | 3.87 |
452.85 | 4.28 | 4.28 |
321.34 | 2.46 | 2.46 |
332.36 | 3.67 | 3.67 |
410.48 | 3.16 | 3.16 |
389.52 | 3.62 | 3.62 |
349.30 | 3.85 | 3.85 |
277.63 | 2.99 | 2.99 |
393.25 | 4.70 | 4.70 |
333.26 | 0.78 | 0.78 |
375.41 | 2.36 | 2.36 |
300.79 | 3.27 | 3.27 |
493.50 | 5.19 | 5.19 |
328.15 | 3.51 | 3.51 |
416.40 | 4.16 | 4.16 |
530.61 | 5.49 | 5.49 |
374.40 | 3.79 | 3.79 |
286.36 | 3.55 | 3.55 |
384.33 | 1.98 | 1.98 |
292.34 | 4.20 | 4.20 |
405.46 | 5.41 | 5.41 |
427.40 | 3.48 | 3.48 |
355.24 | 3.53 | 3.53 |
379.38 | 3.54 | 3.54 |
304.76 | 3.36 | 3.36 |
301.40 | 2.88 | 2.88 |
354.37 | 2.25 | 2.25 |
423.47 | 5.51 | 5.51 |
339.21 | 4.02 | 4.02 |
445.59 | 3.18 | 3.18 |
305.43 | 5.07 | 5.07 |
510.59 | 4.56 | 4.56 |
264.71 | 3.37 | 3.37 |
296.33 | 1.66 | 1.66 |
283.72 | 3.51 | 3.51 |
277.20 | 4.05 | 4.05 |
253.74 | 2.96 | 2.96 |
391.41 | 4.28 | 4.28 |
294.46 | 4.65 | 4.65 |
288.78 | 3.11 | 3.11 |
283.40 | 3.54 | 3.54 |
316.79 | 3.53 | 3.53 |
264.27 | 2.20 | 2.20 |
349.39 | 4.15 | 4.15 |
292.34 | 4.41 | 4.41 |
248.31 | 2.14 | 2.14 |
316.41 | 3.19 | 3.19 |
373.33 | 3.23 | 3.23 |
440.57 | 2.51 | 2.51 |
420.26 | 3.19 | 3.19 |
496.37 | 3.73 | 3.73 |
182.15 | 1.22 | 1.22 |