Basic Information
ID: ALA1738408
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose Response confirmation of small molecule APOBEC3G DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493012, AID493028]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1738408
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 108.10 | 0.25 | 0.25 |
| 237.35 | 2.48 | 2.48 |
| 209.30 | 2.57 | 2.57 |
| 226.23 | 2.23 | 2.23 |
| 227.29 | 3.05 | 3.05 |
| 318.24 | 1.69 | 1.69 |
| 184.65 | 2.50 | 2.50 |
| 258.75 | 3.10 | 3.10 |
| 318.81 | 3.12 | 3.12 |
| 248.38 | 3.65 | 3.65 |
| 398.42 | 3.48 | 3.48 |
| 220.32 | 3.28 | 3.28 |
| 287.10 | 2.77 | 2.77 |
| 240.33 | 3.37 | 3.37 |
| 353.20 | 2.18 | 2.18 |
| 346.37 | 1.60 | 1.60 |
| 266.33 | 0.89 | 0.89 |
| 348.27 | 3.13 | 3.13 |
| 178.31 | 1.94 | 1.94 |
| 373.52 | 6.00 | 6.00 |
| 243.29 | 2.15 | 2.15 |
| 251.35 | 1.90 | 1.90 |
| 585.58 | 2.88 | 2.88 |
| 321.80 | 2.85 | 2.85 |
| 250.28 | 0.79 | 0.79 |
| 223.30 | 2.63 | 2.63 |
| 422.49 | 2.28 | 2.28 |
| 369.76 | 3.27 | 3.27 |
| 305.45 | 3.43 | 3.43 |
| 334.47 | 2.24 | 2.24 |
| 278.34 | 2.94 | 2.94 |
| 336.80 | 1.85 | 1.85 |
| 364.52 | 3.78 | 3.78 |
| 148.16 | 1.25 | 1.25 |
| 259.31 | 3.50 | 3.50 |
| 274.35 | 2.13 | 2.13 |
| 310.38 | 3.59 | 3.59 |
| 370.23 | 1.98 | 1.98 |
| 354.44 | 2.80 | 2.80 |
| 275.30 | 3.20 | 3.20 |
| 421.48 | 2.92 | 2.92 |
| 323.23 | 3.76 | 3.76 |
| 542.71 | 4.95 | 4.95 |
| 404.47 | 2.99 | 2.99 |
| 473.94 | 3.02 | 3.02 |
| 289.34 | 2.40 | 2.40 |
| 467.59 | 4.90 | 4.90 |
| 265.36 | 2.26 | 2.26 |
| 193.23 | 1.47 | 1.47 |
| 432.48 | 2.46 | 2.46 |
| 249.34 | 3.33 | 3.33 |
| 426.48 | 3.55 | 3.55 |
| 207.26 | 1.77 | 1.77 |
| 253.40 | 3.26 | 3.26 |
| 352.49 | 2.45 | 2.45 |
| 398.47 | 3.62 | 3.62 |
| 527.69 | 5.69 | 5.69 |
| 241.32 | 3.36 | 3.36 |
| 253.35 | 2.68 | 2.68 |
| 315.35 | 1.95 | 1.95 |
| 443.57 | 4.22 | 4.22 |
| 334.42 | 2.30 | 2.30 |
| 340.83 | 4.63 | 4.63 |
| 410.47 | 2.12 | 2.12 |
| 271.30 | 3.22 | 3.22 |
| 332.34 | 4.13 | 4.13 |
| 319.39 | 2.26 | 2.26 |
| 376.48 | 3.31 | 3.31 |
| 231.32 | 2.53 | 2.53 |
| 239.32 | 2.58 | 2.58 |
| 343.43 | 3.50 | 3.50 |
| 376.24 | 3.68 | 3.68 |
| 354.47 | 3.45 | 3.45 |
| 267.31 | 2.60 | 2.60 |
| 332.86 | 3.54 | 3.54 |
| 307.80 | 3.61 | 3.61 |
| 264.28 | 1.56 | 1.56 |
| 536.59 | 3.70 | 3.70 |
| 253.33 | 3.22 | 3.22 |
| 239.32 | 2.29 | 2.29 |
| 271.30 | 2.75 | 2.75 |
| 471.00 | 3.58 | 3.58 |
| 357.44 | 3.11 | 3.11 |
| 380.43 | 2.90 | 2.90 |
| 230.09 | 1.96 | 1.96 |
| 276.32 | 2.72 | 2.72 |
| 222.27 | 1.73 | 1.73 |
| 396.45 | 1.73 | 1.73 |
| 247.35 | 3.05 | 3.05 |
| 294.38 | 4.03 | 4.03 |
| 279.37 | 1.60 | 1.60 |
| 457.58 | 4.41 | 4.41 |
| 347.83 | 3.37 | 3.37 |
| 287.41 | 1.79 | 1.79 |
| 239.73 | 2.91 | 2.91 |
| 317.37 | 2.80 | 2.80 |
| 461.57 | 1.91 | 1.91 |
| 235.27 | 1.61 | 1.61 |
| 250.37 | 2.82 | 2.82 |
| 331.31 | 2.93 | 2.93 |
| 367.50 | 3.24 | 3.24 |
| 319.34 | 2.74 | 2.74 |
| 395.49 | ||
| 372.41 | 3.00 | 3.00 |
| 273.39 | 3.21 | 3.21 |
| 427.49 | 5.18 | 5.18 |
| 209.18 | 1.40 | 1.40 |
| 252.30 | 0.87 | 0.87 |
| 267.67 | 1.79 | 1.79 |
| 267.36 | 3.18 | 3.18 |
| 245.31 | 2.49 | 2.49 |
| 278.41 | 1.73 | 1.73 |
| 377.26 | 4.74 | 4.74 |
| 237.35 | 2.87 | 2.87 |
| 257.32 | 2.88 | 2.88 |
| 280.35 | 1.89 | 1.89 |
| 253.40 | 3.26 | 3.26 |
| 360.83 | 2.44 | 2.44 |
| 400.51 | 2.68 | 2.68 |
| 336.48 | 4.45 | 4.45 |
| 260.32 | 1.74 | 1.74 |
| 260.34 | 0.39 | 0.39 |
| 314.38 | 1.04 | 1.04 |
| 542.39 | 5.34 | 5.34 |
| 410.43 | 2.46 | 2.46 |
| 361.47 | 3.07 | 3.07 |
| 234.69 | 1.78 | 1.78 |
| 266.32 | 0.85 | 0.85 |
| 245.28 | 3.19 | 3.19 |
| 294.43 | 3.01 | 3.01 |
| 329.38 | 2.06 | 2.06 |
| 267.36 | 3.18 | 3.18 |
| 536.50 | 2.59 | 2.59 |
| 268.81 | 2.65 | 2.65 |
| 320.40 | 2.61 | 2.61 |
| 288.38 | 2.52 | 2.52 |
| 416.33 | 5.21 | 5.21 |
| 147.23 | 0.87 | 0.87 |
| 303.41 | 3.41 | 3.41 |
| 257.36 | 3.52 | 3.52 |
| 268.35 | 2.97 | 2.97 |
| 265.41 | 3.02 | 3.02 |
| 340.43 | 2.87 | 2.87 |
| 244.12 | 2.27 | 2.27 |
| 396.44 | 4.28 | 4.28 |
| 308.34 | 1.37 | 1.37 |
| 425.94 | 4.96 | 4.96 |
| 406.31 | 3.78 | 3.78 |
| 383.86 | 2.92 | 2.92 |
| 291.40 | 2.76 | 2.76 |
| 288.40 | 3.20 | 3.20 |
| 383.50 | 3.98 | 3.98 |
| 219.31 | 2.43 | 2.43 |
| 310.29 | 2.53 | 2.53 |
| 281.41 | 3.17 | 3.17 |
| 260.39 | 0.96 | 0.96 |
| 447.54 | 3.26 | 3.26 |
| 274.31 | 1.23 | 1.23 |
| 341.21 | 2.94 | 2.94 |
| 476.41 | 4.20 | 4.20 |
| 247.32 | 2.33 | 2.33 |
| 222.32 | 1.09 | 1.09 |
| 473.53 | -0.36 | -0.36 |
| 367.46 | 3.50 | 3.50 |
| 239.37 | 2.88 | 2.88 |
| 361.85 | 3.68 | 3.68 |
| 320.47 | 3.65 | 3.65 |
| 319.14 | 1.09 | 1.09 |
| 340.77 | 3.33 | 3.33 |
| 256.13 | 2.52 | 2.52 |
| 211.68 | 2.41 | 2.41 |
| 381.53 | 4.53 | 4.53 |
| 267.35 | 1.80 | 1.80 |
| 334.42 | 2.49 | 2.49 |
| 305.40 | 2.13 | 2.13 |
| 294.34 | 2.32 | 2.32 |
| 378.41 | 3.39 | 3.39 |
| 192.29 | 2.42 | 2.42 |
| 206.36 | 2.57 | 2.57 |
| 256.72 | 1.51 | 1.51 |
| 283.36 | 3.23 | 3.23 |
| 292.39 | 1.90 | 1.90 |
| 369.84 | 2.97 | 2.97 |
| 286.36 | 3.14 | 3.14 |
| 194.26 | 1.70 | 1.70 |
| 217.30 | 2.32 | 2.32 |
| 281.79 | 3.64 | 3.64 |
| 394.46 | 3.29 | 3.29 |
| 347.37 | 2.16 | 2.16 |
| 407.45 | 3.33 | 3.33 |
| 236.34 | 1.48 | 1.48 |
| 342.46 | 3.15 | 3.15 |
| 388.54 | 2.55 | 2.55 |
| 201.25 | 2.35 | 2.35 |
| 357.44 | 2.69 | 2.69 |
| 258.31 | 1.52 | 1.52 |
| 227.27 | 1.67 | 1.67 |
| 187.31 | 2.49 | 2.49 |
| 360.44 | 2.64 | 2.64 |
| 486.98 | 4.40 | 4.40 |
| 277.35 | 2.44 | 2.44 |
| 274.35 | 3.38 | 3.38 |
| 243.74 | 3.22 | 3.22 |
| 317.44 | 3.23 | 3.23 |
| 295.80 | 3.07 | 3.07 |
| 312.47 | 2.05 | 2.05 |
| 251.33 | 3.03 | 3.03 |
| 226.69 | 1.79 | 1.79 |
| 453.32 | 5.11 | 5.11 |
| 361.18 | 3.68 | 3.68 |
| 331.33 | 3.19 | 3.19 |
| 281.77 | 3.08 | 3.08 |
| 223.24 | 2.40 | 2.40 |
| 247.37 | 3.07 | 3.07 |
| 302.41 | 2.51 | 2.51 |
| 194.26 | 1.50 | 1.50 |
| 343.41 | 1.71 | 1.71 |
| 416.53 | 2.30 | 2.30 |
| 257.32 | 3.12 | 3.12 |
| 271.14 | 1.71 | 1.71 |
| 283.78 | 2.92 | 2.92 |
| 262.29 | 2.33 | 2.33 |
| 256.33 | 2.02 | 2.02 |
| 253.40 | 3.27 | 3.27 |
| 439.47 | 0.43 | 0.43 |
| 287.35 | 1.29 | 1.29 |
| 333.36 | 3.22 | 3.22 |
| 423.52 | 3.60 | 3.60 |
| 361.85 | 3.68 | 3.68 |
| 377.47 | 1.88 | 1.88 |
| 342.26 | 1.96 | 1.96 |
| 348.50 | 2.55 | 2.55 |
| 394.25 | 4.25 | 4.25 |
| 421.45 | 4.43 | 4.43 |
| 190.27 | 2.12 | 2.12 |
| 331.37 | 2.85 | 2.85 |
| 204.30 | 2.43 | 2.43 |
| 496.95 | 2.88 | 2.88 |
| 304.35 | 2.12 | 2.12 |
| 396.45 | 1.73 | 1.73 |
| 283.36 | 3.23 | 3.23 |
| 262.36 | 2.51 | 2.51 |
| 349.41 | 3.19 | 3.19 |
| 409.49 | 2.75 | 2.75 |
| 265.41 | 3.80 | 3.80 |
| 389.48 | 4.00 | 4.00 |
| 454.55 | 3.99 | 3.99 |
| 426.52 | 2.73 | 2.73 |
| 536.63 | 4.37 | 4.37 |
| 327.41 | 1.86 | 1.86 |
| 264.24 | 1.65 | 1.65 |
| 318.33 | 2.50 | 2.50 |
| 245.28 | 3.19 | 3.19 |
| 394.46 | 3.29 | 3.29 |
| 353.47 | 3.97 | 3.97 |
| 301.42 | 2.61 | 2.61 |
| 376.41 | 1.58 | 1.58 |
| 183.28 | 2.14 | 2.14 |
| 331.80 | 3.70 | 3.70 |
| 257.32 | 3.12 | 3.12 |
| 239.73 | 2.91 | 2.91 |
| 267.38 | 2.78 | 2.78 |
| 298.44 | 2.21 | 2.21 |
| 239.73 | 2.73 | 2.73 |
| 374.49 | 3.23 | 3.23 |
| 251.74 | 3.07 | 3.07 |
| 180.24 | 1.03 | 1.03 |
| 332.39 | 3.25 | 3.25 |
| 292.39 | 2.48 | 2.48 |
| 373.41 | 4.29 | 4.29 |
| 288.38 | 2.38 | 2.38 |
| 167.19 | 1.35 | 1.35 |
| 343.50 | 2.57 | 2.57 |
| 236.34 | 1.48 | 1.48 |
| 323.40 | 2.44 | 2.44 |
| 268.70 | 3.08 | 3.08 |
| 273.32 | 0.81 | 0.81 |
| 284.34 | 1.36 | 1.36 |
| 326.45 | 1.80 | 1.80 |
| 453.56 | 4.59 | 4.59 |
| 302.20 | 3.25 | 3.25 |
| 288.38 | 2.50 | 2.50 |
| 293.43 | 4.10 | 4.10 |
| 278.41 | 3.30 | 3.30 |
| 314.21 | 2.47 | 2.47 |
| 367.50 | 4.28 | 4.28 |
| 263.27 | 3.33 | 3.33 |
| 278.40 | 3.47 | 3.47 |
| 438.55 | 2.66 | 2.66 |
| 411.91 | 5.60 | 5.60 |
| 276.36 | 2.61 | 2.61 |
| 285.80 | 2.73 | 2.73 |
| 250.28 | 2.16 | 2.16 |
| 278.29 | 1.23 | 1.23 |
| 274.37 | 2.89 | 2.89 |
| 334.40 | 3.08 | 3.08 |
| 271.32 | 3.36 | 3.36 |
| 251.33 | 3.03 | 3.03 |
| 343.41 | 1.71 | 1.71 |
| 564.09 | 4.66 | 4.66 |
| 297.31 | 1.96 | 1.96 |
| 281.25 | 0.42 | 0.42 |
| 262.29 | 2.33 | 2.33 |
| 286.15 | 2.24 | 2.24 |
| 238.34 | 2.43 | 2.43 |
| 256.30 | 2.11 | 2.11 |
| 356.41 | 3.02 | 3.02 |
| 210.69 | 2.81 | 2.81 |
| 297.81 | 3.31 | 3.31 |
| 396.51 | 2.35 | 2.35 |
| 226.23 | 3.11 | 3.11 |
| 378.58 | 3.27 | 3.27 |
| 352.44 | 3.25 | 3.25 |
| 497.55 | 2.73 | 2.73 |
| 357.44 | 3.56 | 3.56 |
| 232.27 | 0.87 | 0.87 |
| 250.33 | 1.48 | 1.48 |
| 261.31 | 2.53 | 2.53 |
| 380.39 | 3.09 | 3.09 |
| 308.46 | 3.49 | 3.49 |
| 247.35 | 3.05 | 3.05 |
| 348.36 | 3.99 | 3.99 |
| 390.40 | 1.83 | 1.83 |
| 308.39 | 2.95 | 2.95 |
| 344.44 | 4.49 | 4.49 |
| 354.44 | 2.68 | 2.68 |
| 285.17 | 1.63 | 1.63 |
| 497.62 | 4.67 | 4.67 |
| 407.50 | 3.92 | 3.92 |
| 307.46 | 4.49 | 4.49 |
| 273.33 | 3.81 | 3.81 |
| 327.30 | 2.48 | 2.48 |
| 355.41 | 2.53 | 2.53 |
| 284.18 | 3.02 | 3.02 |
| 348.50 | 2.55 | 2.55 |
| 557.68 | 4.56 | 4.56 |
| 267.31 | 1.79 | 1.79 |
| 304.38 | 1.76 | 1.76 |
| 237.28 | 1.78 | 1.78 |
| 391.91 | 4.50 | 4.50 |
| 354.43 | 1.27 | 1.27 |
| 394.46 | 3.21 | 3.21 |
| 248.11 | 1.64 | 1.64 |
| 162.22 | 1.92 | 1.92 |
| 395.49 | 1.63 | 1.63 |
| 234.28 | 2.07 | 2.07 |
| 280.35 | 2.70 | 2.70 |
| 463.99 | 3.60 | 3.60 |
| 288.78 | 3.11 | 3.11 |
| 253.74 | 2.96 | 2.96 |
| 496.41 | 0.22 | 0.22 |
| 330.20 | 3.34 | 3.34 |
| 322.19 | 3.58 | 3.58 |
| 242.76 | 3.40 | 3.40 |
| 382.51 | 1.91 | 1.91 |
| 260.27 | 0.58 | 0.58 |
| 300.79 | 3.27 | 3.27 |
| 315.79 | 3.16 | 3.16 |
| 295.37 | 2.82 | 2.82 |
| 329.34 | 2.93 | 2.93 |
| 289.36 | 3.07 | 3.07 |
| 337.41 | 3.18 | 3.18 |
| 284.34 | 3.02 | 3.02 |
| 298.37 | 2.87 | 2.87 |
| 329.35 | 2.06 | 2.06 |
| 300.35 | 1.85 | 1.85 |
| 355.42 | 3.44 | 3.44 |
| 287.37 | 2.57 | 2.57 |
| 331.40 | 3.66 | 3.66 |
| 315.79 | 3.16 | 3.16 |
| 340.41 | 2.98 | 2.98 |
| 290.37 | 3.08 | 3.08 |
| 439.29 | 4.40 | 4.40 |
| 310.39 | 2.81 | 2.81 |
| 283.36 | 2.45 | 2.45 |
| 280.36 | 3.12 | 3.12 |
| 314.37 | 2.16 | 2.16 |
| 323.38 | 3.42 | 3.42 |
| 321.41 | 3.57 | 3.57 |
| 311.37 | 3.16 | 3.16 |
| 344.40 | 2.16 | 2.16 |
| 329.35 | 2.06 | 2.06 |
| 339.21 | 4.02 | 4.02 |
| 304.40 | 2.52 | 2.52 |
| 284.34 | 2.62 | 2.62 |
| 273.32 | 2.05 | 2.05 |
| 314.37 | 2.16 | 2.16 |
| 355.38 | 2.94 | 2.94 |
| 370.44 | 2.35 | 2.35 |
| 445.59 | 3.18 | 3.18 |
| 295.37 | 2.82 | 2.82 |
| 311.37 | 3.16 | 3.16 |
| 325.35 | 3.02 | 3.02 |
| 375.46 | 3.31 | 3.31 |
| 333.78 | 3.30 | 3.30 |
| 304.40 | 2.52 | 2.52 |
| 311.37 | 2.42 | 2.42 |
| 344.40 | 2.16 | 2.16 |
| 324.41 | 2.58 | 2.58 |
| 281.34 | 2.51 | 2.51 |
| 307.38 | 3.18 | 3.18 |
| 287.14 | 2.11 | 2.11 |
| 374.43 | 2.17 | 2.17 |
| 311.37 | 2.42 | 2.42 |
| 301.40 | 2.88 | 2.88 |
| 330.37 | 1.86 | 1.86 |
| 301.40 | 2.88 | 2.88 |
| 277.20 | 4.05 | 4.05 |
| 253.74 | 2.96 | 2.96 |
| 342.38 | 2.44 | 2.44 |
| 350.23 | 3.82 | 3.82 |
| 326.34 | 2.42 | 2.42 |
| 315.79 | 3.16 | 3.16 |
| 340.41 | 2.34 | 2.34 |
| 281.34 | 2.51 | 2.51 |
| 435.30 | 3.50 | 3.50 |
| 280.36 | 3.12 | 3.12 |
| 295.37 | 2.82 | 2.82 |
| 474.66 | 5.18 | 5.18 |
| 311.37 | 2.42 | 2.42 |
| 299.33 | 2.65 | 2.65 |
| 286.39 | 3.18 | 3.18 |
| 356.41 | 2.84 | 2.84 |
| 475.51 | 2.39 | 2.39 |
| 386.44 | 2.05 | 2.05 |
| 281.34 | 2.51 | 2.51 |
| 307.38 | 3.18 | 3.18 |
| 297.34 | 2.77 | 2.77 |
| 400.46 | 2.35 | 2.35 |
| 370.44 | 2.35 | 2.35 |
| 283.15 | 2.21 | 2.21 |
| 300.34 | 2.62 | 2.62 |
| 301.40 | 2.88 | 2.88 |
| 290.38 | 2.21 | 2.21 |
| 301.40 | 2.88 | 2.88 |
| 284.34 | 3.02 | 3.02 |
| 369.36 | 2.75 | 2.75 |
| 356.41 | 2.04 | 2.04 |
| 356.41 | 2.04 | 2.04 |
| 314.37 | 2.80 | 2.80 |
| 206.32 | 1.37 | 1.37 |
| 274.31 | 1.74 | 1.74 |
| 277.30 | 1.83 | 1.83 |
| 294.40 | 3.34 | 3.34 |
| 303.44 | 2.86 | 2.86 |
| 276.35 | 2.77 | 2.77 |
| 360.79 | 3.07 | 3.07 |
| 326.34 | 2.42 | 2.42 |
| 287.39 | 2.89 | 2.89 |
| 290.37 | 3.08 | 3.08 |
| 337.41 | 3.18 | 3.18 |
| 284.34 | 3.02 | 3.02 |
| 271.31 | 2.10 | 2.10 |
| 288.34 | 2.05 | 2.05 |
| 287.39 | 2.89 | 2.89 |
| 326.34 | 2.42 | 2.42 |
| 370.44 | 2.35 | 2.35 |
| 300.34 | 3.36 | 3.36 |
| 285.33 | 2.41 | 2.41 |