Assay Report Card

Basic Information

ID: ALA1738418

Type: Binding

Description: PUBCHEM_BIOASSAY: Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493008, AID493018, AID504382, AID504383]

Organism: Homo sapiens

Activity Charts

Bioactivity

Activity Types for Assay ALA1738418

EC50

Total(244)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
406.62	3.98	3.98
181.66	0.26	0.26
225.25	2.63	2.63
293.33	3.30	3.30
308.38	2.69	2.69
397.39	2.10	2.10
436.92	3.39	3.39
329.40	2.47	2.47
209.22	1.48	1.48
395.47	4.20	4.20
387.37	3.01	3.01
430.00	2.65	2.65
272.30	2.21	2.21
395.51	4.48	4.48
248.35	2.72	2.72
333.41	1.65	1.65
497.58	5.80	5.80
465.20	4.04	4.04
499.35	4.44	4.44
327.31	4.19	4.19
344.46	3.63	3.63
417.46	4.09	4.09
270.31	-0.03	-0.03
270.79	2.60	2.60
424.96	5.05	5.05
369.85	3.30	3.30
311.39	2.36	2.36
240.26	1.56	1.56
202.21	0.60	0.60
390.46	2.80	2.80
456.45	4.06	4.06
210.23	0.01	0.01
306.63	3.12	3.12
237.31	3.03	3.03
398.47	2.71	2.71
345.81	3.65	3.65
350.89	2.66	2.66
268.32	2.66	2.66
290.41	2.77	2.77
409.45	3.61	3.61
374.51	3.78	3.78
371.49	3.79	3.79
310.40	2.09	2.09
282.30	2.64	2.64
289.40	3.52	3.52
347.37	3.13	3.13
406.59	4.59	4.59
348.81	2.63	2.63
453.35	6.07	6.07
373.36	3.93	3.93
211.27	2.64	2.64
320.35	3.06	3.06
410.50	3.09	3.09
427.38	3.92	3.92
295.77	4.31	4.31
474.65	4.09	4.09
477.49	3.74	3.74
302.35	-0.04	-0.04
418.95	5.25	5.25
360.46	6.20	6.20
497.01	3.78	3.78
344.44	2.75	2.75
262.27	2.51	2.51
336.28	2.08	2.08
200.20	1.84	1.84
463.58	3.16	3.16
403.42	1.45	1.45
353.38	2.67	2.67
417.38	4.58	4.58
279.29	0.95	0.95
243.27	2.74	2.74
327.13	3.94	3.94
376.44	4.18	4.18
427.57	2.96	2.96
414.46	5.38	5.38
256.27	3.73	3.73
443.57	1.88	1.88
286.40	3.71	3.71
245.27	1.15	1.15
225.29	2.71	2.71
355.46	3.21	3.21
289.31	1.33	1.33
301.30	1.59	1.59
308.33	3.98	3.98
421.48	5.82	5.82
365.39	1.98	1.98
227.26	3.61	3.61
319.36	4.29	4.29
364.43	2.09	2.09
215.23	0.86	0.86
317.38	3.06	3.06
320.37	3.83	3.83
400.42	1.17	1.17
482.61	1.60	1.60
351.41	1.63	1.63
333.41	1.92	1.92
453.54	4.50	4.50
393.22	3.56	3.56
309.32	3.05	3.05
353.45	4.48	4.48
288.30	-0.34	-0.34
445.55	4.36	4.36
479.58	2.42	2.42
309.13	4.85	4.85
359.39	5.21	5.21
371.40	4.00	4.00
220.24	2.66	2.66
287.11	2.22	2.22
379.77	5.01	5.01
352.78	5.17	5.17
324.16	4.02	4.02
388.49	2.25	2.25
452.89	3.10	3.10
274.33	3.67	3.67
384.43	4.46	4.46
310.47	3.10	3.10
293.39	3.64	3.64
393.49	3.72	3.72
285.13	3.37	3.37
336.40	4.69	4.69
436.51	2.68	2.68
524.64	5.43	5.43
394.54	4.45	4.45
321.34	3.35	3.35
347.40	0.93	0.93
265.32	3.13	3.13
359.41	1.76	1.76
356.40	2.92	2.92
329.20	3.53	3.53
477.50	1.88	1.88
347.80	3.58	3.58
418.50	2.30	2.30
271.18	3.83	3.83
339.36	0.95	0.95
359.81	3.46	3.46
350.42	4.36	4.36
422.47	3.40	3.40
281.31	3.59	3.59
354.36	2.38	2.38
286.45	2.27	2.27
229.33	3.09	3.09
319.32	3.36	3.36
356.38	2.64	2.64
366.39	3.69	3.69
397.30	5.25	5.25
280.42	2.86	2.86
357.28	2.65	2.65
349.49	3.22	3.22
256.26	1.78	1.78
359.43	3.86	3.86
388.49	1.81	1.81
373.46	6.04	6.04
224.26	3.52	3.52
382.38	1.87	1.87
327.38	4.56	4.56
349.39	3.69	3.69
394.47	2.43	2.43
315.44	2.62	2.62
315.21	2.98	2.98
474.41	5.39	5.39
275.38	2.46	2.46
220.25	0.61	0.61
290.71	2.51	2.51
416.31	4.13	4.13
330.36	2.97	2.97
332.45	4.01	4.01
405.52	4.34	4.34
398.87	4.15	4.15
256.35	1.16	1.16
399.45	3.28	3.28
372.42	4.34	4.34
316.43	1.34	1.34
320.48	4.02	4.02
384.53	3.51	3.51
458.49	2.34	2.34
341.47	3.56	3.56
276.36	3.03	3.03
494.53	1.24	1.24
292.35	3.54	3.54
354.34	1.90	1.90
421.13	4.33	4.33
339.42	4.07	4.07
388.58	3.11	3.11
307.42	2.69	2.69
313.31	2.49	2.49
362.48	4.27	4.27
349.82	4.50	4.50
368.49	4.39	4.39
464.50	4.16	4.16
380.45	4.51	4.51
293.35	0.51	0.51
344.85	-1.52	-1.52
339.44	1.90	1.90
443.48	2.57	2.57
486.57	4.02	4.02
447.56	4.40	4.40
329.31	1.96	1.96
419.51	-0.17	-0.17
323.13	2.28	2.28
380.40	2.46	2.46
376.93	3.05	3.05
348.41	2.61	2.61
281.31	2.16	2.16
530.55	4.71	4.71
292.30	3.59	3.59
143.58	1.02	1.02
479.52	4.64	4.64
486.62	4.45	4.45
438.55	3.73	3.73
291.28	1.76	1.76
349.25	4.26	4.26
611.92	6.00	6.00
375.38	-0.02	-0.02
312.35	2.65	2.65
457.62	5.93	5.93
330.82	2.66	2.66
361.44	4.14	4.14
358.45	0.97	0.97
404.25	5.42	5.42
338.37	1.35	1.35
389.52	3.62	3.62
381.46	2.72	2.72
321.34	4.33	4.33
563.65	4.62	4.62
342.42	2.17	2.17
362.43	4.40	4.40
468.89	4.35	4.35
307.35	3.86	3.86
296.35	3.37	3.37
365.46	3.01	3.01
335.36	4.06	4.06
303.67	3.41	3.41
290.24	0.95	0.95
295.37	2.82	2.82
278.32	2.63	2.63
332.41	3.49	3.49
497.57	2.83	2.83
410.93	3.87	3.87
498.52	1.50	1.50
293.28	1.26	1.26
289.64	3.54	3.54
354.41	1.69	1.69
230.31	2.95	2.95
340.35	3.02	3.02