Assay Report Card

Basic Information

ID: ALA1738485

Type: Functional

Description: PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485273, AID485343, AID493155]

Organism: Homo sapiens

Activity Charts

Bioactivity

Activity Types for Assay ALA1738485

IC50

Total(353)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
403.98	3.94	3.94
505.46	4.18	4.18
299.50	3.92	3.92
337.81	4.43	4.43
510.06	6.08	6.08
289.34	0.64	0.64
243.29	2.36	2.36
576.69	7.25	7.25
580.54	-1.17	-1.17
301.52	4.15	4.15
614.56	7.32	7.32
467.57	4.62	4.62
525.07	5.35	5.35
462.52	6.52	6.52
337.21	3.39	3.39
473.99	4.31	4.31
406.46	2.13	2.13
591.72	8.05	8.05
687.71	10.29	10.29
238.81	-0.36	-0.36
427.35	4.38	4.38
545.08	4.67	4.67
359.39	1.61	1.61
551.63	2.59	2.59
443.58	4.80	4.80
277.30	4.14	4.14
514.61	5.39	5.39
422.49	2.03	2.03
631.22	4.66	4.66
599.22	5.26	5.26
344.46	5.09	5.09
461.61	3.02	3.02
503.47	4.33	4.33
459.57	2.71	2.71
462.12	6.38	6.38
448.55	4.83	4.83
524.67	4.16	4.16
705.22	2.53	2.53
349.37	3.33	3.33
482.63	3.58	3.58
503.08	5.74	5.74
315.38	4.76	4.76
465.53	3.09	3.09
260.34	4.24	4.24
337.38	2.88	2.88
509.61	3.65	3.65
396.86	1.62	1.62
490.59	5.01	5.01
442.93	4.20	4.20
451.96	3.47	3.47
538.04	2.70	2.70
424.52	0.48	0.48
438.67	6.28	6.28
417.49	4.27	4.27
321.40	1.11	1.11
316.18	1.10	1.10
323.37	0.51	0.51
422.65	2.72	2.72
351.28	3.08	3.08
438.96	4.37	4.37
528.63	3.91	3.91
276.37	4.04	4.04
421.43	5.24	5.24
468.51	3.65	3.65
320.40	2.75	2.75
303.36	3.58	3.58
488.41	3.35	3.35
531.05	4.74	4.74
446.51	3.28	3.28
532.63	3.30	3.30
344.33	5.52	5.52
481.58	3.48	3.48
366.35	1.75	1.75
267.31	0.44	0.44
441.55	3.97	3.97
603.21	5.11	5.11
640.75	6.38	6.38
475.57	2.33	2.33
423.24	4.26	4.26
384.51	4.02	4.02
595.19	4.23	4.23
579.23	5.46	5.46
486.55	2.61	2.61
513.58	2.88	2.88
334.46	5.04	5.04
334.43	2.03	2.03
437.45	2.83	2.83
488.05	4.35	4.35
304.38	3.42	3.42
501.45	4.09	4.09
456.40	4.33	4.33
370.43	1.98	1.98
335.43	3.65	3.65
439.58	1.77	1.77
321.38	4.52	4.52
312.35	4.06	4.06
299.35	3.00	3.00
539.57	-0.61	-0.61
396.43	3.08	3.08
448.49	6.21	6.21
277.30	4.14	4.14
386.77	2.10	2.10
506.63	5.30	5.30
444.90	3.31	3.31
593.38	5.51	5.51
409.96	2.71	2.71
562.65	3.39	3.39
461.57	3.01	3.01
390.43	2.89	2.89
399.52	1.96	1.96
420.47	3.65	3.65
447.41	2.65	2.65
295.35	1.43	1.43
290.39	4.39	4.39
498.63	3.33	3.33
480.03	3.45	3.45
601.19	4.65	4.65
399.56	4.09	4.09
542.66	4.30	4.30
486.96	3.54	3.54
246.26	2.71	2.71
437.55	4.25	4.25
538.07	4.90	4.90
272.33	1.24	1.24
345.43	4.47	4.47
484.60	3.31	3.31
466.47	5.94	5.94
455.30	3.54	3.54
536.12	4.45	4.45
585.20	4.95	4.95
441.53	3.52	3.52
482.61	3.88	3.88
529.62	5.01	5.01
403.39	0.12	0.12
323.33	2.80	2.80
358.42	3.61	3.61
282.76	2.91	2.91
321.40	1.11	1.11
581.72	3.98	3.98
464.62	4.15	4.15
603.17	4.44	4.44
445.74	3.20	3.20
339.42	2.93	2.93
459.55	2.59	2.59
545.27	4.26	4.26
391.42	4.33	4.33
451.96	3.47	3.47
432.36	4.33	4.33
469.57	3.28	3.28
531.63	3.77	3.77
465.33	2.37	2.37
454.55	2.69	2.69
539.03	3.45	3.45
450.95	5.43	5.43
615.22	5.04	5.04
547.50	4.40	4.40
304.74	1.14	1.14
304.42	4.77	4.77
406.87	4.61	4.61
317.35	2.60	2.60
642.68	6.29	6.29
508.09	5.69	5.69
288.31	3.03	3.03
507.50	6.38	6.38
306.39	3.51	3.51
397.53	1.54	1.54
558.53	4.97	4.97
483.59	3.66	3.66
631.22	4.66	4.66
465.69	5.31	5.31
397.52	3.13	3.13
417.47	2.81	2.81
296.33	2.52	2.52
458.93	3.62	3.62
364.41	3.51	3.51
341.38	3.33	3.33
332.43	4.04	4.04
309.39	1.52	1.52
536.12	4.45	4.45
421.48	4.11	4.11
503.08	5.74	5.74
473.56	2.08	2.08
245.28	2.23	2.23
403.56	4.76	4.76
387.44	2.42	2.42
415.47	2.41	2.41
317.35	4.15	4.15
396.47	3.77	3.77
406.47	4.41	4.41
497.52	2.80	2.80
351.43	1.26	1.26
415.71	2.74	2.74
383.43	2.85	2.85
377.45	3.34	3.34
381.26	3.93	3.93
1001.73	1.28	1.28
476.60	5.29	5.29
524.06	3.11	3.11
296.37	1.92	1.92
413.59	3.59	3.59
376.89	4.85	4.85
551.08	9.23	9.23
342.36	0.79	0.79
516.69	3.10	3.10
615.22	5.04	5.04
496.96	2.16	2.16
597.72	3.76	3.76
418.50	3.09	3.09
483.71	3.76	3.76
478.57	1.93	1.93
310.38	4.66	4.66
496.01	2.10	2.10
331.76	1.81	1.81
544.48	3.28	3.28
336.38	3.91	3.91
601.19	4.65	4.65
538.09	3.58	3.58
411.51	3.51	3.51
504.81	5.69	5.69
536.07	3.22	3.22
352.42	2.62	2.62
335.43	1.62	1.62
359.84	3.71	3.71
571.24	5.01	5.01
616.05	5.22	5.22
480.68	4.11	4.11
607.63	5.41	5.41
537.05	8.84	8.84
631.22	4.88	4.88
408.41	1.39	1.39
587.21	5.33	5.33
463.46	3.29	3.29
814.84	5.62	5.62
370.43	3.82	3.82
467.55	3.17	3.17
386.77	2.10	2.10
363.83	1.72	1.72
534.68	3.24	3.24
360.44	2.65	2.65
384.45	3.76	3.76
352.38	3.39	3.39
474.54	3.20	3.20
451.96	3.64	3.64
567.13	3.80	3.80
339.18	1.79	1.79
599.22	5.20	5.20
406.48	3.65	3.65
420.32	2.47	2.47
465.62	4.18	4.18
317.86	3.53	3.53
925.11	-1.49	-1.49
483.55	2.87	2.87
349.43	3.78	3.78
309.33	2.10	2.10
361.79	1.30	1.30
898.09	-1.91	-1.91
445.58	5.95	5.95
511.62	4.51	4.51
937.17	-1.38	-1.38
393.51	1.03	1.03
966.21	-0.89	-0.89
909.16	-0.31	-0.31
421.43	5.24	5.24
419.92	-0.03	-0.03
446.00	2.02	2.02
387.37	4.02	4.02
1001.73	1.28	1.28
425.58	2.32	2.32
981.23	-1.46	-1.46
392.51	4.11	4.11
644.78	-1.13	-1.13
461.58	2.65	2.65
897.10	-1.97	-1.97
967.15	-3.06	-3.06
577.91	5.80	5.80
853.05	-1.90	-1.90
532.49	4.77	4.77
381.45	0.93	0.93
318.36	0.37	0.37
487.60	3.34	3.34
993.28	0.20	0.20
471.55	3.67	3.67
502.61	3.15	3.15
1246.66
1218.65
351.41	4.02	4.02
1222.66
329.45	3.77	3.77
1306.78
1306.78
1162.54
1306.78
1329.84
1306.78
1222.66
392.42	3.97	3.97
1275.74
1162.54
1317.78
374.44	3.66	3.66
358.38	3.72	3.72
396.43	0.58	0.58
302.40	4.54	4.54
300.39	4.45	4.45
330.41	4.46	4.46
302.77	2.74	2.74
320.37	1.81	1.81
320.37	1.81	1.81
419.46	3.00	3.00
350.40	1.82	1.82
299.36	2.28	2.28
343.41	3.37	3.37
309.34	4.14	4.14
261.31	1.19	1.19
330.37	2.37	2.37
347.42	2.83	2.83
464.47	4.62	4.62
250.30	2.02	2.02
350.38	3.14	3.14
739.66	5.72	5.72
332.79	2.53	2.53
330.37	2.37	2.37
420.64	3.76	3.76