Assay Report Card

Basic Information

ID: ALA1738494

Type: Functional

Description: PUBCHEM_BIOASSAY: Dose response cytotoxicity of uHTS chemical inhibitors of T-cell specific antigen receptor-induced NF-kB activation in a HEK-293T cell line using a luminescence assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID435003, AID435012, AID489041]

Cell type: HEK-293T

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
414.412.412.41
363.371.661.66
853.923.743.74
399.442.872.87
255.704.264.26
239.253.753.75
221.263.613.61
167.200.600.60
339.352.442.44
302.413.623.62
253.251.491.49
331.803.333.33
853.923.743.74
282.394.424.42
371.432.952.95
233.273.213.21
194.243.093.09
390.522.582.58
404.501.901.90
281.351.041.04
287.102.772.77
414.412.762.76
365.392.712.71
152.12-0.96-0.96
309.343.113.11
374.523.603.60
286.241.091.09
244.21-3.17-3.17
412.473.343.34
398.422.242.24
408.452.652.65
426.442.792.79
452.462.382.38
273.303.953.95
311.343.213.21
241.251.911.91
282.323.023.02
234.331.461.46
457.911.851.85
246.312.282.28
289.322.732.73
506.486.096.09
232.322.772.77
288.393.313.31
923.053.523.52
357.413.213.21
295.353.043.04
507.98-0.79-0.79
496.035.845.84
362.475.075.07
334.424.254.25
381.404.704.70
436.544.644.64
466.564.654.65
380.273.063.06
362.905.045.04
488.415.175.17
422.354.264.26
290.373.943.94
368.393.153.15
410.344.584.58
207.19-1.32-1.32
488.445.885.88
193.17-1.63-1.63
476.546.836.83
346.342.692.69
314.341.091.09
394.303.543.54
403.315.645.64
323.403.733.73
350.423.953.95
405.545.185.18
334.424.294.29
352.424.614.61
386.865.265.26
200.242.572.57
641.164.094.09
591.728.058.05
429.934.514.51
346.383.083.08
313.404.654.65
312.332.662.66
529.113.883.88
412.422.402.40
374.695.095.09
487.944.504.50
342.383.193.19
365.393.683.68
373.434.974.97
321.814.174.17
351.413.473.47
498.633.103.10
318.334.064.06
378.744.144.14
379.494.374.37
440.324.414.41
366.985.365.36
528.007.287.28
350.423.733.73
406.402.482.48
311.343.293.29
390.312.832.83
290.392.492.49
452.344.494.49
382.372.662.66
413.893.743.74
811.883.163.16
484.582.232.23
253.283.643.64
530.506.606.60
219.273.573.57
399.412.742.74
451.553.573.57
458.974.214.21
298.373.343.34
384.463.543.54
248.202.232.23
315.343.553.55
277.334.974.97
429.473.353.35
279.303.353.35
344.374.534.53
313.353.563.56
280.332.902.90
304.262.962.96
339.393.723.72
379.493.583.58
319.364.184.18
365.434.214.21
452.584.224.22
307.303.323.32
325.363.683.68
340.395.865.86
346.412.572.57
338.414.434.43
400.461.891.89
390.485.615.61
304.291.921.92
324.384.124.12
340.423.703.70
355.311.931.93
272.261.831.83
373.384.494.49
375.474.234.23
526.037.897.89
312.372.022.02
469.543.713.71
226.283.403.40
375.383.303.30
263.304.664.66
281.363.323.32
260.253.063.06
440.732.742.74
417.523.493.49
348.255.655.65
328.423.453.45
290.373.103.10
527.027.037.03
418.501.971.97
399.303.933.93
433.583.763.76
401.523.313.31
362.484.154.15
355.854.244.24
368.464.644.64
388.402.662.66
386.386.036.03
425.554.284.28
333.483.423.42
356.383.103.10
340.383.283.28
320.373.933.93
280.354.784.78
446.915.055.05
380.455.045.04
867.953.663.66
364.404.824.82
845.943.783.78
400.434.464.46
299.333.173.17
344.843.703.70
370.414.464.46
387.484.104.10
383.383.083.08
424.374.074.07
370.412.872.87
368.464.644.64
358.372.652.65
458.542.792.79
363.393.753.75
439.512.662.66
261.364.004.00
290.343.093.09
431.511.911.91
422.874.814.81
325.363.683.68
327.383.933.93
312.393.623.62
331.444.174.17
331.444.114.11
407.425.105.10
341.413.433.43
340.383.283.28
265.313.123.12
342.404.324.32
321.414.214.21
435.443.013.01
378.486.566.56
390.414.294.29
359.314.544.54
415.303.633.63
251.292.732.73
378.464.314.31
367.503.213.21
392.844.814.81
348.401.771.77
323.424.464.46
419.724.284.28
483.586.946.94
378.484.274.27
393.533.603.60
338.414.434.43
345.365.055.05
438.404.464.46
300.363.373.37
267.242.532.53
341.372.852.85
360.443.393.39
368.464.644.64
351.323.933.93
447.405.605.60
271.281.161.16
338.363.133.13
400.823.443.44
413.484.934.93
354.392.722.72
389.294.144.14
295.384.184.18
554.098.268.26
323.780.750.75
276.322.482.48
398.354.644.64
831.913.393.39
360.483.683.68
249.274.364.36
415.533.513.51
338.404.244.24
305.343.493.49
475.552.882.88
289.362.022.02
386.441.501.50
423.473.753.75
311.392.662.66
384.493.763.76
309.414.564.56
430.374.074.07
316.743.533.53
508.554.374.37
405.503.563.56
330.412.922.92
370.474.044.04
442.503.383.38
491.613.523.52
377.494.404.40
384.464.424.42
363.473.513.51
400.464.044.04
494.983.003.00
517.41-0.14-0.14
222.673.133.13
311.173.793.79
374.445.085.08
422.363.523.52
414.513.773.77
392.382.092.09
569.585.735.73
293.283.303.30
301.154.454.45
429.883.053.05
326.624.204.20
418.076.616.61
449.313.523.52
325.363.333.33
287.313.013.01
380.444.734.73
371.433.823.82
303.342.702.70
262.313.803.80
418.565.065.06
459.523.533.53
415.244.004.00
511.825.435.43
399.883.833.83
431.303.303.30
455.492.922.92
342.414.304.30
400.504.264.26
509.665.305.30
338.404.244.24
322.373.493.49
346.773.323.32
374.684.734.73
276.773.213.21
663.905.225.22
404.493.853.85
428.964.774.77
443.533.833.83
310.382.722.72
384.464.344.34
328.393.353.35
360.234.554.55
437.532.242.24
289.363.083.08
320.393.863.86
867.095.955.95
443.572.952.95
293.373.663.66
427.475.555.55
452.584.144.14
285.343.003.00
266.303.083.08
299.323.933.93
367.323.633.63
392.463.383.38
347.424.824.82
362.824.084.08
310.273.443.44
335.373.033.03
402.402.452.45
375.343.763.76
409.245.355.35
519.405.165.16
369.423.803.80
441.543.343.34
378.914.094.09
391.223.423.42
334.804.024.02
437.404.274.27
395.463.493.49
301.301.271.27
326.353.313.31
450.494.464.46
430.284.184.18
334.164.684.68
287.322.912.91
358.272.752.75
270.25-0.56-0.56
368.464.524.52
276.362.182.18
340.383.873.87
352.431.811.81
300.322.802.80
475.614.284.28
338.484.084.08
311.343.003.00
404.475.095.09
342.401.651.65
429.484.914.91
468.564.314.31
297.362.862.86
425.605.455.45
654.713.123.12
483.993.793.79
369.263.523.52
346.362.252.25
314.393.523.52
289.722.522.52
831.913.393.39
789.882.822.82
411.483.213.21
833.933.473.47
293.672.192.19
508.672.862.86
342.244.414.41
847.954.004.00
377.404.714.71
343.431.231.23
395.435.095.09
269.302.182.18
441.635.405.40
347.443.493.49
369.804.334.33
405.481.531.53
336.473.173.17
480.345.665.66
351.443.593.59
536.972.692.69
284.273.203.20
404.384.064.06
342.444.114.11
344.234.934.93
304.402.162.16
502.495.015.01
302.802.642.64
327.823.713.71
324.413.373.37
384.463.713.71
567.487.307.30
477.573.173.17
368.464.354.35
309.373.343.34
356.264.934.93
366.453.763.76
366.424.424.42
330.412.792.79
384.435.135.13
363.253.003.00
465.775.945.94
349.413.063.06
352.514.384.38
283.332.432.43
438.553.873.87
351.433.413.41
419.724.284.28
401.305.395.39
286.362.972.97
477.403.613.61
237.263.113.11
260.292.892.89
474.993.823.82
345.444.134.13
372.853.363.36
427.476.266.26
410.323.773.77
477.954.334.33
430.914.084.08
255.272.952.95
363.403.823.82
355.441.651.65
464.354.874.87
494.532.802.80
351.474.664.66
368.494.224.22
386.432.602.60
313.404.654.65
373.372.852.85
520.594.244.24
382.453.343.34
403.353.853.85
367.433.003.00
280.282.922.92
368.864.994.99
289.242.802.80
409.444.774.77
396.404.754.75
389.482.712.71
368.464.354.35
380.402.052.05
377.374.974.97
384.483.293.29
350.423.813.81
447.583.893.89
363.444.284.28
390.372.942.94
301.394.214.21
406.414.964.96
377.493.593.59
335.373.033.03
294.313.613.61
284.343.563.56
474.603.523.52
343.433.713.71
385.873.783.78
254.342.722.72
346.413.013.01
295.393.903.90
293.332.672.67
391.472.152.15
419.554.954.95
309.424.374.37
349.824.364.36
441.414.854.85
399.455.255.25
360.434.644.64
403.444.084.08
404.424.854.85
349.394.194.19
347.392.652.65
431.474.534.53
346.412.152.15
373.821.841.84
384.464.344.34
401.334.824.82
456.572.732.73
425.313.983.98
357.413.993.99
377.443.643.64
300.363.633.63
455.305.835.83
467.593.093.09
329.404.184.18
415.884.574.57
372.383.873.87
359.843.983.98
431.562.802.80
287.325.045.04
394.432.262.26
341.484.694.69
475.364.194.19
442.465.905.90
410.504.694.69
474.524.334.33
322.373.583.58
339.915.095.09
463.333.453.45
363.464.014.01
249.323.803.80
335.025.145.14
328.424.474.47
489.374.084.08
354.844.604.60
371.392.242.24
396.874.574.57
407.303.543.54
396.472.672.67
303.793.913.91
811.883.163.16
574.632.522.52
315.304.114.11
329.313.223.22
294.442.442.44
354.434.334.33
438.43-1.00-1.00
410.463.813.81
429.933.603.60
327.413.483.48
484.042.962.96
359.393.853.85
314.393.683.68
400.484.284.28
332.342.522.52
337.384.144.14
362.433.313.31
239.253.753.75
358.814.754.75
405.433.123.12
296.373.463.46
416.515.035.03
346.822.672.67
656.662.752.75
332.374.624.62
480.973.173.17
208.263.403.40
317.413.863.86
378.382.902.90
312.872.712.71
385.273.623.62
378.904.014.01
390.443.683.68
282.302.352.35
274.323.563.56
392.412.732.73
373.143.763.76
338.485.085.08
360.463.813.81
346.394.944.94
586.68-1.44-1.44
293.783.333.33
395.534.444.44
382.535.235.23
336.442.692.69
396.473.723.72
364.390.740.74
543.555.625.62
464.913.783.78
467.572.812.81
437.541.981.98
402.402.812.81
388.453.513.51
355.424.144.14
418.473.993.99
384.383.223.22
338.443.443.44
274.322.242.24
313.353.033.03
381.404.704.70
358.423.143.14
368.464.644.64
432.554.244.24
415.493.843.84
385.312.222.22
395.433.063.06
434.523.173.17
319.576.176.17
313.403.483.48
293.373.903.90
353.384.084.08
317.413.233.23
395.463.423.42
429.523.333.33
421.523.713.71
297.331.501.50
390.412.982.98
363.392.352.35
376.432.632.63
416.444.224.22
382.293.803.80
360.214.154.15
378.483.943.94
283.334.314.31
318.343.203.20
384.401.421.42
395.435.095.09
500.064.194.19
409.924.884.88
423.523.963.96
361.494.364.36
459.963.333.33
334.384.204.20
423.903.923.92
1013.29
365.422.902.90
463.604.094.09
252.282.342.34
359.585.985.98
385.382.092.09
747.972.912.91
484.603.673.67
390.422.422.42
791.035.125.12
334.333.043.04
348.452.952.95
463.993.603.60
399.492.872.87
423.521.661.66
343.384.494.49
477.634.304.30
453.553.963.96
398.412.922.92
362.392.652.65
365.372.452.45
351.484.584.58
459.633.573.57
284.272.562.56
305.384.314.31
574.491.111.11
351.414.024.02
360.413.893.89
359.183.663.66
380.414.324.32
432.504.324.32
358.324.334.33
371.243.483.48
443.302.902.90
304.353.093.09
437.523.483.48
335.404.754.75
401.502.962.96
452.746.016.01
346.224.554.55
498.615.445.44
386.484.684.68
346.381.801.80
414.384.464.46
461.365.035.03
254.323.143.14
374.753.933.93
302.362.352.35
308.173.543.54
418.915.155.15
448.325.375.37
374.403.033.03
496.594.044.04
371.402.772.77
408.504.434.43
423.343.883.88
349.464.504.50
372.454.434.43
302.340.800.80
378.351.161.16
434.473.773.77
370.213.473.47
436.494.054.05
392.482.662.66
402.315.545.54
282.343.953.95
853.923.743.74
452.513.913.91
496.593.813.81
320.353.993.99
324.302.782.78
347.445.555.55
376.444.524.52
357.412.252.25
321.342.012.01
309.344.144.14
315.423.403.40
392.253.333.33
427.471.671.67
319.343.403.40
286.292.552.55
347.641.731.73
230.230.730.73