ID: ALA1738508
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS small molecule inhibitors of tim23-1 yeast via a luminescent assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463212, AID463216, AID504657, AID504672]
Organism: Saccharomyces cerevisiae S288c
Bioactivity
Activity Types for Assay ALA1738508
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
215.03 | 3.10 | 3.10 |
180.21 | 2.78 | 2.78 |
351.86 | 2.69 | 2.69 |
251.25 | -0.95 | -0.95 |
270.24 | 2.58 | 2.58 |
292.14 | 3.00 | 3.00 |
239.23 | 1.75 | 1.75 |
240.33 | 3.85 | 3.85 |
271.28 | 3.14 | 3.14 |
317.42 | 4.97 | 4.97 |
281.31 | 3.11 | 3.11 |
336.42 | 4.56 | 4.56 |
238.25 | 2.96 | 2.96 |
224.26 | 3.24 | 3.24 |
285.33 | 3.36 | 3.36 |
287.32 | 3.58 | 3.58 |
227.29 | 3.20 | 3.20 |
489.59 | 5.94 | 5.94 |
329.34 | 2.94 | 2.94 |
290.37 | 3.54 | 3.54 |
579.99 | 0.00 | 0.00 |
229.30 | 3.23 | 3.23 |
209.25 | 2.99 | 2.99 |
362.47 | 5.07 | 5.07 |
295.37 | 3.70 | 3.70 |
327.39 | 5.05 | 5.05 |
297.36 | 5.04 | 5.04 |
521.05 | 4.09 | 4.09 |
400.83 | 4.27 | 4.27 |
274.24 | 2.95 | 2.95 |
304.39 | 4.65 | 4.65 |
270.28 | 2.86 | 2.86 |
376.37 | 2.82 | 2.82 |
283.33 | 3.33 | 3.33 |
342.39 | 4.01 | 4.01 |
419.41 | 3.07 | 3.07 |
288.37 | 3.77 | 3.77 |
374.44 | 3.51 | 3.51 |
310.42 | 3.44 | 3.44 |
320.35 | 3.06 | 3.06 |
381.34 | 3.44 | 3.44 |
320.32 | 2.41 | 2.41 |
420.52 | 2.01 | 2.01 |
291.79 | 3.79 | 3.79 |
314.45 | 4.34 | 4.34 |
361.45 | 3.69 | 3.69 |
341.44 | 2.88 | 2.88 |
343.41 | 2.13 | 2.13 |
444.92 | 5.04 | 5.04 |
326.18 | 4.06 | 4.06 |
374.48 | 4.24 | 4.24 |
295.30 | 3.00 | 3.00 |
201.22 | 2.45 | 2.45 |
348.43 | 4.45 | 4.45 |
311.37 | 3.50 | 3.50 |
301.37 | 3.58 | 3.58 |
331.36 | 2.98 | 2.98 |
294.25 | 4.01 | 4.01 |
523.41 | 5.24 | 5.24 |
319.39 | 4.32 | 4.32 |
247.30 | 3.28 | 3.28 |
256.26 | 2.81 | 2.81 |
350.18 | 4.80 | 4.80 |
278.31 | 4.07 | 4.07 |
421.93 | 3.74 | 3.74 |
269.33 | 3.13 | 3.13 |
190.16 | 1.85 | 1.85 |
456.34 | 4.02 | 4.02 |
417.90 | 4.47 | 4.47 |
290.39 | 4.31 | 4.31 |
259.31 | 3.39 | 3.39 |
301.35 | 1.77 | 1.77 |
281.29 | 3.47 | 3.47 |
290.39 | 4.31 | 4.31 |
367.31 | 3.27 | 3.27 |
311.37 | 3.47 | 3.47 |
268.35 | 2.68 | 2.68 |
251.28 | 2.69 | 2.69 |
358.40 | 3.46 | 3.46 |
274.30 | 1.42 | 1.42 |
356.40 | 2.07 | 2.07 |
357.46 | 5.04 | 5.04 |
444.53 | 5.75 | 5.75 |
275.31 | 3.85 | 3.85 |
268.77 | 2.87 | 2.87 |
258.35 | 3.47 | 3.47 |
408.41 | 3.39 | 3.39 |
370.86 | 5.21 | 5.21 |
312.38 | 4.74 | 4.74 |
280.42 | 4.06 | 4.06 |
387.44 | 3.83 | 3.83 |
331.36 | 2.66 | 2.66 |
341.39 | 2.56 | 2.56 |
321.42 | 4.95 | 4.95 |
343.38 | 3.85 | 3.85 |
317.35 | 4.16 | 4.16 |
363.64 | 4.11 | 4.11 |
363.80 | 4.72 | 4.72 |
258.32 | 2.85 | 2.85 |
218.28 | 3.45 | 3.45 |
365.44 | 3.11 | 3.11 |
375.81 | 3.24 | 3.24 |
229.30 | 3.19 | 3.19 |
348.41 | 3.98 | 3.98 |
398.44 | 2.31 | 2.31 |
354.38 | 3.07 | 3.07 |
325.80 | 4.03 | 4.03 |
322.37 | 2.55 | 2.55 |
335.39 | 4.45 | 4.45 |
254.26 | 3.59 | 3.59 |
287.17 | 4.31 | 4.31 |
254.24 | 2.93 | 2.93 |
305.38 | 4.32 | 4.32 |
264.31 | 3.28 | 3.28 |
309.39 | 4.45 | 4.45 |
249.67 | 3.73 | 3.73 |
336.35 | 3.87 | 3.87 |
331.17 | 3.00 | 3.00 |
251.31 | 2.54 | 2.54 |
293.33 | 3.89 | 3.89 |
266.30 | 3.46 | 3.46 |
251.28 | 3.99 | 3.99 |
386.86 | 4.91 | 4.91 |
416.92 | 3.60 | 3.60 |
317.44 | 4.84 | 4.84 |
277.53 | 3.93 | 3.93 |
252.36 | 3.33 | 3.33 |
314.82 | 4.61 | 4.61 |
328.37 | 2.84 | 2.84 |
283.24 | 2.21 | 2.21 |
378.50 | 4.64 | 4.64 |
312.32 | 3.66 | 3.66 |
242.30 | 3.41 | 3.41 |
286.35 | 3.92 | 3.92 |
293.26 | 2.03 | 2.03 |
261.32 | 4.37 | 4.37 |
362.45 | 4.59 | 4.59 |
227.26 | 2.95 | 2.95 |
295.34 | 2.91 | 2.91 |
288.78 | 4.09 | 4.09 |
339.38 | 2.76 | 2.76 |
383.47 | 3.92 | 3.92 |
265.27 | 3.18 | 3.18 |
259.38 | 3.44 | 3.44 |
236.73 | 1.94 | 1.94 |
227.26 | 2.95 | 2.95 |
254.25 | 3.59 | 3.59 |
286.36 | 4.46 | 4.46 |
309.33 | 2.67 | 2.67 |
307.28 | 3.18 | 3.18 |
490.59 | 4.25 | 4.25 |
226.30 | 3.57 | 3.57 |
339.37 | 4.36 | 4.36 |
304.37 | 3.07 | 3.07 |
221.21 | 1.23 | 1.23 |
323.35 | 3.62 | 3.62 |
283.30 | 3.67 | 3.67 |
233.27 | 3.71 | 3.71 |
368.37 | 3.74 | 3.74 |
262.26 | 3.28 | 3.28 |
247.64 | 2.48 | 2.48 |
284.75 | 4.21 | 4.21 |
207.66 | 2.90 | 2.90 |
355.44 | 2.73 | 2.73 |
385.22 | 4.55 | 4.55 |
407.41 | 3.21 | 3.21 |
343.82 | 3.86 | 3.86 |
330.43 | 3.50 | 3.50 |
336.39 | 2.94 | 2.94 |
329.22 | 4.05 | 4.05 |
345.38 | 2.96 | 2.96 |
425.49 | 3.93 | 3.93 |
366.26 | 4.03 | 4.03 |
252.34 | 4.06 | 4.06 |
297.75 | 3.47 | 3.47 |
236.13 | 2.56 | 2.56 |
292.69 | 3.64 | 3.64 |
262.27 | 3.60 | 3.60 |
319.74 | 3.39 | 3.39 |
287.37 | 3.52 | 3.52 |
314.37 | 3.57 | 3.57 |
339.37 | 4.40 | 4.40 |
223.66 | 2.60 | 2.60 |
447.54 | 3.26 | 3.26 |
312.38 | 3.67 | 3.67 |
263.35 | 1.83 | 1.83 |
290.33 | 2.41 | 2.41 |
336.46 | 3.26 | 3.26 |
414.42 | 4.13 | 4.13 |
227.35 | 2.74 | 2.74 |
306.34 | 4.82 | 4.82 |
326.38 | 3.17 | 3.17 |
303.39 | 3.67 | 3.67 |
320.37 | 4.81 | 4.81 |
235.25 | 2.30 | 2.30 |
295.37 | 4.20 | 4.20 |
286.36 | 4.06 | 4.06 |
376.43 | 3.36 | 3.36 |
322.41 | 4.20 | 4.20 |
367.79 | 5.24 | 5.24 |
278.31 | 2.66 | 2.66 |
313.57 | 4.77 | 4.77 |
238.70 | 3.35 | 3.35 |
348.41 | 2.71 | 2.71 |
241.33 | 4.36 | 4.36 |
254.34 | 2.76 | 2.76 |
340.33 | 3.34 | 3.34 |
314.37 | 3.26 | 3.26 |
300.54 | 3.95 | 3.95 |
221.69 | 3.15 | 3.15 |
355.42 | 2.95 | 2.95 |
281.79 | 3.64 | 3.64 |
274.55 | 3.45 | 3.45 |
310.22 | 4.42 | 4.42 |
309.32 | 3.86 | 3.86 |
318.37 | 3.12 | 3.12 |
294.26 | 1.10 | 1.10 |
385.81 | 2.59 | 2.59 |
271.70 | 3.51 | 3.51 |
323.44 | 4.06 | 4.06 |
321.40 | 2.08 | 2.08 |
348.40 | 4.70 | 4.70 |
275.38 | 3.70 | 3.70 |
524.67 | 4.33 | 4.33 |
272.33 | 3.52 | 3.52 |
252.74 | 3.75 | 3.75 |
260.30 | 3.03 | 3.03 |
266.25 | 3.05 | 3.05 |
321.38 | 3.36 | 3.36 |
423.56 | 3.81 | 3.81 |
296.33 | 3.37 | 3.37 |
269.34 | 3.89 | 3.89 |
247.26 | 2.40 | 2.40 |
256.33 | 3.09 | 3.09 |
345.34 | 1.12 | 1.12 |
321.16 | 3.85 | 3.85 |
363.64 | 4.11 | 4.11 |
351.32 | 4.30 | 4.30 |
237.71 | 3.65 | 3.65 |
280.35 | 4.22 | 4.22 |
380.27 | 3.66 | 3.66 |
343.45 | 3.88 | 3.88 |
292.09 | 3.21 | 3.21 |
400.41 | 1.89 | 1.89 |
422.53 | 5.95 | 5.95 |
346.45 | 3.49 | 3.49 |
363.44 | 4.39 | 4.39 |
352.44 | 5.38 | 5.38 |
330.77 | 3.95 | 3.95 |
315.33 | 4.14 | 4.14 |
308.38 | 1.41 | 1.41 |
317.14 | 3.06 | 3.06 |
254.26 | 3.59 | 3.59 |
255.70 | 3.83 | 3.83 |
254.74 | 2.48 | 2.48 |
279.34 | 3.13 | 3.13 |
222.33 | 3.78 | 3.78 |
289.72 | 3.36 | 3.36 |
319.39 | 4.54 | 4.54 |
259.38 | 3.87 | 3.87 |
408.41 | 3.39 | 3.39 |
324.47 | 4.10 | 4.10 |
291.35 | 4.41 | 4.41 |
459.91 | 3.45 | 3.45 |
343.41 | 1.28 | 1.28 |
317.14 | 2.95 | 2.95 |
289.36 | 3.60 | 3.60 |
391.25 | 4.61 | 4.61 |
293.35 | 1.52 | 1.52 |
368.86 | 4.99 | 4.99 |
446.51 | 5.93 | 5.93 |
249.36 | 3.33 | 3.33 |
405.43 | 3.68 | 3.68 |
323.39 | 3.84 | 3.84 |
299.42 | 4.63 | 4.63 |
332.41 | 2.88 | 2.88 |
303.32 | 3.85 | 3.85 |
355.82 | 4.86 | 4.86 |
365.48 | 4.10 | 4.10 |
257.29 | 2.42 | 2.42 |
329.36 | 5.48 | 5.48 |
312.33 | 2.78 | 2.78 |
307.38 | 1.83 | 1.83 |
388.25 | 4.90 | 4.90 |
340.81 | 4.20 | 4.20 |
198.22 | 3.81 | 3.81 |
282.30 | 3.98 | 3.98 |
300.84 | 4.41 | 4.41 |
334.17 | 3.47 | 3.47 |
296.29 | 1.29 | 1.29 |
347.20 | 5.27 | 5.27 |
306.19 | 4.21 | 4.21 |
202.21 | 2.02 | 2.02 |
295.30 | 1.89 | 1.89 |
450.85 | 5.14 | 5.14 |
251.74 | 3.85 | 3.85 |
278.40 | 3.64 | 3.64 |
254.36 | 4.66 | 4.66 |
372.40 | 2.77 | 2.77 |
276.32 | 2.43 | 2.43 |
419.27 | 4.91 | 4.91 |
335.35 | 4.25 | 4.25 |
372.18 | 4.43 | 4.43 |
355.42 | 2.70 | 2.70 |
315.36 | 3.02 | 3.02 |
409.90 | 4.72 | 4.72 |
238.25 | 4.09 | 4.09 |
429.93 | 4.28 | 4.28 |
299.17 | 4.30 | 4.30 |
321.79 | 3.20 | 3.20 |
400.39 | 3.82 | 3.82 |
291.37 | 2.48 | 2.48 |
320.35 | 3.64 | 3.64 |
264.35 | 3.29 | 3.29 |
376.39 | 1.62 | 1.62 |
323.33 | 2.57 | 2.57 |
384.82 | 4.25 | 4.25 |
298.41 | 4.43 | 4.43 |
232.24 | 1.40 | 1.40 |
274.70 | 3.50 | 3.50 |
322.39 | 3.88 | 3.88 |
474.58 | 3.09 | 3.09 |
467.88 | 4.27 | 4.27 |
294.38 | 4.37 | 4.37 |
267.20 | 1.20 | 1.20 |
294.31 | 4.68 | 4.68 |
442.47 | 4.22 | 4.22 |
340.42 | 4.09 | 4.09 |
322.82 | 3.25 | 3.25 |
294.35 | 3.47 | 3.47 |
383.76 | 5.10 | 5.10 |
381.48 | 4.33 | 4.33 |
266.30 | 3.46 | 3.46 |
402.45 | 5.03 | 5.03 |
342.45 | 4.23 | 4.23 |
350.17 | 2.89 | 2.89 |
263.30 | 3.33 | 3.33 |
414.44 | 2.20 | 2.20 |
358.46 | 3.27 | 3.27 |
362.41 | 4.00 | 4.00 |
341.39 | 2.78 | 2.78 |
320.35 | 3.25 | 3.25 |
260.36 | 3.24 | 3.24 |
259.31 | 2.51 | 2.51 |
215.25 | 2.03 | 2.03 |
350.33 | 2.29 | 2.29 |
329.38 | 2.79 | 2.79 |
300.43 | 3.87 | 3.87 |
372.42 | 4.15 | 4.15 |
228.25 | 2.97 | 2.97 |
352.42 | 3.84 | 3.84 |
259.35 | 2.36 | 2.36 |
313.36 | 4.04 | 4.04 |
355.78 | 3.57 | 3.57 |
339.35 | 2.84 | 2.84 |
320.35 | 3.25 | 3.25 |
247.29 | 3.70 | 3.70 |
337.81 | 4.50 | 4.50 |
261.75 | 3.65 | 3.65 |
313.38 | 3.34 | 3.34 |
476.56 | 3.99 | 3.99 |
416.46 | 1.64 | 1.64 |
277.33 | 3.62 | 3.62 |
291.31 | 3.34 | 3.34 |
295.36 | 3.48 | 3.48 |
349.82 | 4.46 | 4.46 |
383.34 | 4.21 | 4.21 |
304.20 | 2.83 | 2.83 |
315.37 | 3.02 | 3.02 |
284.38 | 2.80 | 2.80 |
326.74 | 3.11 | 3.11 |
456.55 | 6.34 | 6.34 |
237.26 | 2.32 | 2.32 |
369.53 | 4.54 | 4.54 |
330.79 | 4.80 | 4.80 |
421.01 | 4.00 | 4.00 |
304.44 | 3.62 | 3.62 |
264.28 | 3.76 | 3.76 |
339.22 | 4.05 | 4.05 |
390.44 | 3.88 | 3.88 |
317.44 | 4.55 | 4.55 |
283.36 | 3.49 | 3.49 |
321.30 | 4.21 | 4.21 |
386.52 | 3.98 | 3.98 |
381.55 | 4.27 | 4.27 |
349.39 | 3.88 | 3.88 |
244.73 | 3.11 | 3.11 |
341.36 | 4.50 | 4.50 |
278.31 | 4.07 | 4.07 |
257.72 | 3.99 | 3.99 |
311.20 | 3.77 | 3.77 |
295.77 | 3.40 | 3.40 |
305.45 | 3.56 | 3.56 |
250.72 | 3.82 | 3.82 |
214.29 | 3.60 | 3.60 |
254.31 | 3.58 | 3.58 |
300.16 | 3.90 | 3.90 |
273.33 | 2.90 | 2.90 |
281.34 | 4.00 | 4.00 |
272.74 | 4.29 | 4.29 |
307.35 | 3.35 | 3.35 |
400.50 | 2.58 | 2.58 |
372.42 | 5.02 | 5.02 |
275.16 | 3.77 | 3.77 |
221.28 | 3.21 | 3.21 |
424.50 | 4.70 | 4.70 |
303.39 | 3.52 | 3.52 |
283.72 | 3.28 | 3.28 |
378.33 | 3.44 | 3.44 |
303.40 | 3.87 | 3.87 |
223.66 | 2.28 | 2.28 |
450.50 | 2.24 | 2.24 |
297.35 | 3.20 | 3.20 |
350.44 | 4.57 | 4.57 |
416.48 | 2.34 | 2.34 |
271.40 | 4.57 | 4.57 |
391.45 | 4.76 | 4.76 |
329.38 | 1.82 | 1.82 |
267.26 | 3.77 | 3.77 |
437.46 | 2.44 | 2.44 |
368.25 | 2.73 | 2.73 |
384.42 | 1.92 | 1.92 |
205.26 | 3.90 | 3.90 |
236.27 | 3.45 | 3.45 |
249.27 | 3.63 | 3.63 |
294.23 | 3.31 | 3.31 |
268.15 | 3.58 | 3.58 |
267.73 | 3.85 | 3.85 |
314.39 | 3.43 | 3.43 |
327.37 | 2.80 | 2.80 |
343.42 | 2.94 | 2.94 |
489.37 | 5.15 | 5.15 |
342.15 | 4.20 | 4.20 |
294.18 | 3.76 | 3.76 |
277.33 | 3.19 | 3.19 |
220.23 | 4.43 | 4.43 |
302.31 | 3.65 | 3.65 |
282.34 | 3.06 | 3.06 |
333.41 | 2.39 | 2.39 |
337.38 | 2.89 | 2.89 |
339.78 | 3.49 | 3.49 |
289.25 | 1.72 | 1.72 |
376.46 | 3.77 | 3.77 |
246.70 | 2.53 | 2.53 |
454.53 | 4.70 | 4.70 |
290.78 | 3.74 | 3.74 |
262.32 | 3.67 | 3.67 |
358.20 | 3.06 | 3.06 |
357.39 | 2.90 | 2.90 |
315.22 | 3.34 | 3.34 |
276.28 | 1.82 | 1.82 |
388.31 | 4.37 | 4.37 |
257.25 | 2.75 | 2.75 |
333.19 | 3.74 | 3.74 |
347.19 | 3.98 | 3.98 |
403.44 | 3.57 | 3.57 |
246.29 | 2.77 | 2.77 |
343.41 | 3.41 | 3.41 |
302.36 | 2.59 | 2.59 |
298.41 | 3.70 | 3.70 |
362.39 | 4.66 | 4.66 |
307.31 | 2.26 | 2.26 |
346.42 | 4.06 | 4.06 |
302.77 | 2.74 | 2.74 |
251.35 | 2.78 | 2.78 |
353.38 | 2.89 | 2.89 |
412.81 | 2.73 | 2.73 |
286.32 | 3.20 | 3.20 |
360.46 | 2.40 | 2.40 |
335.23 | 3.90 | 3.90 |
294.81 | 3.63 | 3.63 |
313.14 | 3.94 | 3.94 |
273.39 | 4.19 | 4.19 |
286.36 | 2.63 | 2.63 |
294.33 | 1.91 | 1.91 |
358.74 | 2.62 | 2.62 |
372.76 | 2.92 | 2.92 |
350.37 | 3.35 | 3.35 |
326.18 | 1.72 | 1.72 |
254.31 | 3.75 | 3.75 |
263.68 | 2.59 | 2.59 |
333.19 | 3.74 | 3.74 |
356.77 | 3.22 | 3.22 |
242.23 | 2.13 | 2.13 |
481.14 | 3.81 | 3.81 |
385.22 | 4.85 | 4.85 |
327.73 | 2.61 | 2.61 |
230.66 | 1.98 | 1.98 |
361.39 | 3.90 | 3.90 |
300.27 | 2.58 | 2.58 |
276.28 | 1.82 | 1.82 |
265.27 | 2.59 | 2.59 |
367.07 | 2.35 | 2.35 |
322.32 | 2.57 | 2.57 |
347.42 | 2.81 | 2.81 |
310.38 | 3.67 | 3.67 |
348.23 | 3.76 | 3.76 |
254.25 | 2.79 | 2.79 |
385.22 | 3.63 | 3.63 |
353.42 | 3.07 | 3.07 |
401.49 | 5.04 | 5.04 |
235.67 | 2.06 | 2.06 |
310.40 | 3.48 | 3.48 |
426.42 | 4.32 | 4.32 |
378.48 | 3.65 | 3.65 |
279.32 | 1.85 | 1.85 |
302.40 | 2.54 | 2.54 |
260.32 | 3.16 | 3.16 |
302.37 | 3.53 | 3.53 |
307.35 | 4.34 | 4.34 |