Basic Information
ID: ALA1738512
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS small molecule inhibitors of tim23-1: a luminescent TIM10 yeast counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463212, AID463216, AID493002]
Organism: Saccharomyces cerevisiae S288c
Activity Charts
Bioactivity
Activity Types for Assay ALA1738512
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 215.03 | 3.10 | 3.10 |
| 180.21 | 2.78 | 2.78 |
| 351.86 | 2.69 | 2.69 |
| 270.24 | 2.58 | 2.58 |
| 292.14 | 3.00 | 3.00 |
| 240.33 | 3.85 | 3.85 |
| 271.28 | 3.14 | 3.14 |
| 317.42 | 4.97 | 4.97 |
| 336.42 | 4.56 | 4.56 |
| 238.25 | 2.96 | 2.96 |
| 287.32 | 3.58 | 3.58 |
| 227.29 | 3.20 | 3.20 |
| 489.59 | 5.94 | 5.94 |
| 329.34 | 2.94 | 2.94 |
| 229.30 | 3.23 | 3.23 |
| 362.47 | 5.07 | 5.07 |
| 327.39 | 5.05 | 5.05 |
| 297.36 | 5.04 | 5.04 |
| 283.33 | 3.33 | 3.33 |
| 342.39 | 4.01 | 4.01 |
| 419.41 | 3.07 | 3.07 |
| 288.37 | 3.77 | 3.77 |
| 374.44 | 3.51 | 3.51 |
| 320.35 | 3.06 | 3.06 |
| 320.32 | 2.41 | 2.41 |
| 420.52 | 2.01 | 2.01 |
| 343.41 | 2.13 | 2.13 |
| 444.92 | 5.04 | 5.04 |
| 295.30 | 3.00 | 3.00 |
| 201.22 | 2.45 | 2.45 |
| 311.37 | 3.50 | 3.50 |
| 523.41 | 5.24 | 5.24 |
| 319.39 | 4.32 | 4.32 |
| 256.26 | 2.81 | 2.81 |
| 350.18 | 4.80 | 4.80 |
| 278.31 | 4.07 | 4.07 |
| 421.93 | 3.74 | 3.74 |
| 190.16 | 1.85 | 1.85 |
| 456.34 | 4.02 | 4.02 |
| 259.31 | 3.39 | 3.39 |
| 290.39 | 4.31 | 4.31 |
| 367.31 | 3.27 | 3.27 |
| 251.28 | 2.69 | 2.69 |
| 274.30 | 1.42 | 1.42 |
| 444.53 | 5.75 | 5.75 |
| 268.77 | 2.87 | 2.87 |
| 312.38 | 4.74 | 4.74 |
| 280.42 | 4.06 | 4.06 |
| 387.44 | 3.83 | 3.83 |
| 331.36 | 2.66 | 2.66 |
| 341.39 | 2.56 | 2.56 |
| 321.42 | 4.95 | 4.95 |
| 343.38 | 3.85 | 3.85 |
| 363.64 | 4.11 | 4.11 |
| 365.44 | 3.11 | 3.11 |
| 375.81 | 3.24 | 3.24 |
| 229.30 | 3.19 | 3.19 |
| 348.41 | 3.98 | 3.98 |
| 398.44 | 2.31 | 2.31 |
| 354.38 | 3.07 | 3.07 |
| 325.80 | 4.03 | 4.03 |
| 287.17 | 4.31 | 4.31 |
| 254.24 | 2.93 | 2.93 |
| 305.38 | 4.32 | 4.32 |
| 264.31 | 3.28 | 3.28 |
| 249.67 | 3.73 | 3.73 |
| 331.17 | 3.00 | 3.00 |
| 266.30 | 3.46 | 3.46 |
| 386.86 | 4.91 | 4.91 |
| 416.92 | 3.60 | 3.60 |
| 317.44 | 4.84 | 4.84 |
| 277.53 | 3.93 | 3.93 |
| 314.82 | 4.61 | 4.61 |
| 283.24 | 2.21 | 2.21 |
| 312.32 | 3.66 | 3.66 |
| 242.30 | 3.41 | 3.41 |
| 286.35 | 3.92 | 3.92 |
| 293.26 | 2.03 | 2.03 |
| 261.32 | 4.37 | 4.37 |
| 362.45 | 4.59 | 4.59 |
| 227.26 | 2.95 | 2.95 |
| 295.34 | 2.91 | 2.91 |
| 288.78 | 4.09 | 4.09 |
| 383.47 | 3.92 | 3.92 |
| 265.27 | 3.18 | 3.18 |
| 259.38 | 3.44 | 3.44 |
| 236.73 | 1.94 | 1.94 |
| 227.26 | 2.95 | 2.95 |
| 254.25 | 3.59 | 3.59 |
| 286.36 | 4.46 | 4.46 |
| 309.33 | 2.67 | 2.67 |
| 304.37 | 3.07 | 3.07 |
| 221.21 | 1.23 | 1.23 |
| 323.35 | 3.62 | 3.62 |
| 283.30 | 3.67 | 3.67 |
| 233.27 | 3.71 | 3.71 |
| 368.37 | 3.74 | 3.74 |
| 207.66 | 2.90 | 2.90 |
| 343.82 | 3.86 | 3.86 |
| 336.39 | 2.94 | 2.94 |
| 329.22 | 4.05 | 4.05 |
| 345.38 | 2.96 | 2.96 |
| 366.26 | 4.03 | 4.03 |
| 297.75 | 3.47 | 3.47 |
| 262.27 | 3.60 | 3.60 |
| 287.37 | 3.52 | 3.52 |
| 314.37 | 3.57 | 3.57 |
| 339.37 | 4.40 | 4.40 |
| 447.54 | 3.26 | 3.26 |
| 312.38 | 3.67 | 3.67 |
| 263.35 | 1.83 | 1.83 |
| 290.33 | 2.41 | 2.41 |
| 227.35 | 2.74 | 2.74 |
| 326.38 | 3.17 | 3.17 |
| 303.39 | 3.67 | 3.67 |
| 320.37 | 4.81 | 4.81 |
| 286.36 | 4.06 | 4.06 |
| 367.79 | 5.24 | 5.24 |
| 278.31 | 2.66 | 2.66 |
| 313.57 | 4.77 | 4.77 |
| 348.41 | 2.71 | 2.71 |
| 241.33 | 4.36 | 4.36 |
| 340.33 | 3.34 | 3.34 |
| 314.37 | 3.26 | 3.26 |
| 221.69 | 3.15 | 3.15 |
| 355.42 | 2.95 | 2.95 |
| 281.79 | 3.64 | 3.64 |
| 310.22 | 4.42 | 4.42 |
| 294.26 | 1.10 | 1.10 |
| 348.40 | 4.70 | 4.70 |
| 260.30 | 3.03 | 3.03 |
| 423.56 | 3.81 | 3.81 |
| 296.33 | 3.37 | 3.37 |
| 269.34 | 3.89 | 3.89 |
| 256.33 | 3.09 | 3.09 |
| 345.34 | 1.12 | 1.12 |
| 351.32 | 4.30 | 4.30 |
| 280.35 | 4.22 | 4.22 |
| 292.09 | 3.21 | 3.21 |
| 400.41 | 1.89 | 1.89 |
| 422.53 | 5.95 | 5.95 |
| 363.44 | 4.39 | 4.39 |
| 352.44 | 5.38 | 5.38 |
| 330.77 | 3.95 | 3.95 |
| 315.33 | 4.14 | 4.14 |
| 308.38 | 1.41 | 1.41 |
| 255.70 | 3.83 | 3.83 |
| 222.33 | 3.78 | 3.78 |
| 289.72 | 3.36 | 3.36 |
| 319.39 | 4.54 | 4.54 |
| 459.91 | 3.45 | 3.45 |
| 317.14 | 2.95 | 2.95 |
| 391.25 | 4.61 | 4.61 |
| 446.51 | 5.93 | 5.93 |
| 249.36 | 3.33 | 3.33 |
| 323.39 | 3.84 | 3.84 |
| 299.42 | 4.63 | 4.63 |
| 332.41 | 2.88 | 2.88 |
| 303.32 | 3.85 | 3.85 |
| 365.48 | 4.10 | 4.10 |
| 257.29 | 2.42 | 2.42 |
| 329.36 | 5.48 | 5.48 |
| 307.38 | 1.83 | 1.83 |
| 388.25 | 4.90 | 4.90 |
| 340.81 | 4.20 | 4.20 |
| 282.30 | 3.98 | 3.98 |
| 300.84 | 4.41 | 4.41 |
| 296.29 | 1.29 | 1.29 |
| 347.20 | 5.27 | 5.27 |
| 306.19 | 4.21 | 4.21 |
| 202.21 | 2.02 | 2.02 |
| 450.85 | 5.14 | 5.14 |
| 372.40 | 2.77 | 2.77 |
| 276.32 | 2.43 | 2.43 |
| 372.18 | 4.43 | 4.43 |
| 355.42 | 2.70 | 2.70 |
| 315.36 | 3.02 | 3.02 |
| 238.25 | 4.09 | 4.09 |
| 429.93 | 4.28 | 4.28 |
| 299.17 | 4.30 | 4.30 |
| 376.39 | 1.62 | 1.62 |
| 323.33 | 2.57 | 2.57 |
| 298.41 | 4.43 | 4.43 |
| 274.70 | 3.50 | 3.50 |
| 322.39 | 3.88 | 3.88 |
| 467.88 | 4.27 | 4.27 |
| 294.38 | 4.37 | 4.37 |
| 267.20 | 1.20 | 1.20 |
| 294.31 | 4.68 | 4.68 |
| 442.47 | 4.22 | 4.22 |
| 322.82 | 3.25 | 3.25 |
| 381.48 | 4.33 | 4.33 |
| 402.45 | 5.03 | 5.03 |
| 350.17 | 2.89 | 2.89 |
| 263.30 | 3.33 | 3.33 |
| 414.44 | 2.20 | 2.20 |
| 259.31 | 2.51 | 2.51 |
| 215.25 | 2.03 | 2.03 |
| 350.33 | 2.29 | 2.29 |
| 372.42 | 4.15 | 4.15 |
| 352.42 | 3.84 | 3.84 |
| 259.35 | 2.36 | 2.36 |
| 320.35 | 3.25 | 3.25 |
| 247.29 | 3.70 | 3.70 |
| 337.81 | 4.50 | 4.50 |
| 261.75 | 3.65 | 3.65 |
| 313.38 | 3.34 | 3.34 |
| 416.46 | 1.64 | 1.64 |
| 277.33 | 3.62 | 3.62 |
| 295.36 | 3.48 | 3.48 |
| 304.20 | 2.83 | 2.83 |
| 326.74 | 3.11 | 3.11 |
| 456.55 | 6.34 | 6.34 |
| 237.26 | 2.32 | 2.32 |
| 369.53 | 4.54 | 4.54 |
| 421.01 | 4.00 | 4.00 |
| 304.44 | 3.62 | 3.62 |
| 264.28 | 3.76 | 3.76 |
| 283.36 | 3.49 | 3.49 |
| 321.30 | 4.21 | 4.21 |
| 381.55 | 4.27 | 4.27 |
| 349.39 | 3.88 | 3.88 |
| 244.73 | 3.11 | 3.11 |
| 278.31 | 4.07 | 4.07 |
| 257.72 | 3.99 | 3.99 |
| 295.77 | 3.40 | 3.40 |
| 250.72 | 3.82 | 3.82 |
| 214.29 | 3.60 | 3.60 |
| 281.34 | 4.00 | 4.00 |
| 272.74 | 4.29 | 4.29 |
| 400.50 | 2.58 | 2.58 |
| 372.42 | 5.02 | 5.02 |
| 424.50 | 4.70 | 4.70 |
| 283.72 | 3.28 | 3.28 |
| 416.48 | 2.34 | 2.34 |
| 271.40 | 4.57 | 4.57 |
| 329.38 | 1.82 | 1.82 |
| 267.26 | 3.77 | 3.77 |
| 437.46 | 2.44 | 2.44 |
| 205.26 | 3.90 | 3.90 |
| 294.23 | 3.31 | 3.31 |
| 268.15 | 3.58 | 3.58 |
| 327.37 | 2.80 | 2.80 |
| 489.37 | 5.15 | 5.15 |
| 342.15 | 4.20 | 4.20 |
| 294.18 | 3.76 | 3.76 |
| 277.33 | 3.19 | 3.19 |
| 220.23 | 4.43 | 4.43 |
| 282.34 | 3.06 | 3.06 |
| 333.41 | 2.39 | 2.39 |
| 339.78 | 3.49 | 3.49 |
| 289.25 | 1.72 | 1.72 |
| 376.46 | 3.77 | 3.77 |
| 246.70 | 2.53 | 2.53 |
| 290.78 | 3.74 | 3.74 |
| 262.32 | 3.67 | 3.67 |
| 358.20 | 3.06 | 3.06 |
| 315.22 | 3.34 | 3.34 |
| 276.28 | 1.82 | 1.82 |
| 257.25 | 2.75 | 2.75 |
| 333.19 | 3.74 | 3.74 |
| 347.19 | 3.98 | 3.98 |
| 403.44 | 3.57 | 3.57 |
| 246.29 | 2.77 | 2.77 |
| 353.38 | 2.89 | 2.89 |
| 286.32 | 3.20 | 3.20 |
| 360.46 | 2.40 | 2.40 |
| 335.23 | 3.90 | 3.90 |
| 294.81 | 3.63 | 3.63 |
| 313.14 | 3.94 | 3.94 |
| 273.39 | 4.19 | 4.19 |
| 286.36 | 2.63 | 2.63 |
| 294.33 | 1.91 | 1.91 |
| 358.74 | 2.62 | 2.62 |
| 372.76 | 2.92 | 2.92 |
| 326.18 | 1.72 | 1.72 |
| 254.31 | 3.75 | 3.75 |
| 263.68 | 2.59 | 2.59 |
| 356.77 | 3.22 | 3.22 |
| 242.23 | 2.13 | 2.13 |
| 481.14 | 3.81 | 3.81 |
| 327.73 | 2.61 | 2.61 |
| 230.66 | 1.98 | 1.98 |
| 300.27 | 2.58 | 2.58 |
| 276.28 | 1.82 | 1.82 |
| 367.07 | 2.35 | 2.35 |
| 347.42 | 2.81 | 2.81 |
| 348.23 | 3.76 | 3.76 |
| 254.25 | 2.79 | 2.79 |
| 385.22 | 3.63 | 3.63 |
| 353.42 | 3.07 | 3.07 |
| 235.67 | 2.06 | 2.06 |
| 279.32 | 1.85 | 1.85 |
| 302.40 | 2.54 | 2.54 |
| 307.35 | 4.34 | 4.34 |