Basic Information
ID: ALA1738549
Type: Functional
Description: PUBCHEM_BIOASSAY: MITF Orthogonal Assay: MALME3 CTG Assay Measured in Cell-Based System Using Plate Reader - 2084-04_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488944]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1738549
AC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 327.39 | 5.09 | 5.09 |
| 394.32 | 4.13 | 4.13 |
| 224.26 | 3.32 | 3.32 |
| 288.31 | 3.36 | 3.36 |
| 283.71 | 3.63 | 3.63 |
| 290.32 | 3.59 | 3.59 |
| 275.22 | 1.66 | 1.66 |
| 330.34 | 2.19 | 2.19 |
| 289.32 | 2.73 | 2.73 |
| 290.32 | 2.49 | 2.49 |
| 307.40 | 3.13 | 3.13 |
| 388.41 | 2.77 | 2.77 |
| 455.82 | 4.06 | 4.06 |
| 487.63 | 4.92 | 4.92 |
| 404.30 | 3.81 | 3.81 |
| 344.54 | 3.83 | 3.83 |
| 332.40 | 3.88 | 3.88 |
| 441.02 | 5.14 | 5.14 |
| 314.34 | 1.09 | 1.09 |
| 290.32 | 3.66 | 3.66 |
| 284.27 | 2.54 | 2.54 |
| 481.35 | 4.07 | 4.07 |
| 241.08 | 2.54 | 2.54 |
| 266.23 | 2.07 | 2.07 |
| 247.68 | 2.29 | 2.29 |
| 396.58 | 5.07 | 5.07 |
| 308.90 | 4.15 | 4.15 |
| 479.49 | 5.83 | 5.83 |
| 406.79 | 5.06 | 5.06 |
| 279.34 | 3.51 | 3.51 |
| 473.23 | 4.43 | 4.43 |
| 386.50 | 4.37 | 4.37 |
| 402.79 | 2.91 | 2.91 |
| 240.20 | 1.95 | 1.95 |
| 480.56 | 3.63 | 3.63 |
| 454.87 | 4.06 | 4.06 |
| 427.44 | 3.93 | 3.93 |
| 254.24 | 2.57 | 2.57 |
| 317.26 | 2.70 | 2.70 |
| 416.78 | 5.61 | 5.61 |
| 464.64 | 3.84 | 3.84 |
| 424.50 | 3.61 | 3.61 |
| 362.47 | 4.64 | 4.64 |
| 343.38 | 3.91 | 3.91 |
| 311.72 | 3.00 | 3.00 |
| 393.57 | 5.30 | 5.30 |
| 397.82 | 3.25 | 3.25 |
| 379.39 | 2.61 | 2.61 |
| 303.16 | 3.65 | 3.65 |
| 324.17 | 2.14 | 2.14 |
| 396.86 | 1.62 | 1.62 |
| 251.24 | 2.83 | 2.83 |
| 260.25 | 3.06 | 3.06 |
| 311.17 | 3.05 | 3.05 |
| 397.43 | 1.85 | 1.85 |
| 252.66 | 2.58 | 2.58 |
| 328.42 | 3.45 | 3.45 |
| 473.06 | 4.75 | 4.75 |
| 458.40 | 4.78 | 4.78 |
| 411.48 | 1.50 | 1.50 |
| 532.91 | 5.44 | 5.44 |
| 417.51 | 1.56 | 1.56 |
| 519.91 | 5.90 | 5.90 |
| 243.27 | 2.74 | 2.74 |
| 425.87 | 3.17 | 3.17 |
| 402.84 | 4.47 | 4.47 |
| 318.20 | 2.25 | 2.25 |
| 387.48 | 4.54 | 4.54 |
| 444.53 | 2.60 | 2.60 |
| 422.96 | 5.09 | 5.09 |
| 386.41 | 2.89 | 2.89 |
| 316.34 | 3.51 | 3.51 |
| 420.85 | 3.40 | 3.40 |
| 246.34 | 3.26 | 3.26 |
| 409.42 | 2.62 | 2.62 |
| 295.29 | 2.74 | 2.74 |
| 450.29 | 5.40 | 5.40 |
| 492.55 | 3.61 | 3.61 |
| 404.35 | 4.11 | 4.11 |
| 374.34 | 2.50 | 2.50 |
| 463.56 | 4.14 | 4.14 |
| 373.31 | 3.33 | 3.33 |
| 348.43 | 4.03 | 4.03 |
| 397.26 | 2.21 | 2.21 |
| 352.03 | 2.38 | 2.38 |
| 266.32 | 2.68 | 2.68 |
| 386.41 | 2.74 | 2.74 |
| 335.75 | 3.69 | 3.69 |
| 394.41 | 1.52 | 1.52 |
| 448.10 | 2.38 | 2.38 |
| 297.74 | 3.94 | 3.94 |
| 420.43 | 3.40 | 3.40 |
| 513.48 | 4.12 | 4.12 |
| 379.48 | 5.15 | 5.15 |
| 251.76 | 3.59 | 3.59 |
| 292.12 | 0.41 | 0.41 |
| 360.35 | 2.28 | 2.28 |
| 261.71 | 3.66 | 3.66 |
| 391.43 | 2.51 | 2.51 |
| 320.35 | 2.66 | 2.66 |
| 306.24 | 3.04 | 3.04 |
| 420.00 | 4.68 | 4.68 |
| 368.46 | 3.86 | 3.86 |
| 459.36 | 2.67 | 2.67 |
| 307.40 | 3.48 | 3.48 |
| 387.37 | 3.76 | 3.76 |
| 458.45 | 3.42 | 3.42 |
| 403.51 | 4.85 | 4.85 |
| 472.37 | 4.70 | 4.70 |
| 365.47 | 4.49 | 4.49 |
| 475.46 | 5.79 | 5.79 |
| 417.87 | 3.36 | 3.36 |
| 404.81 | 3.16 | 3.16 |
| 360.46 | 3.95 | 3.95 |
| 465.00 | 6.64 | 6.64 |
| 310.25 | 3.35 | 3.35 |
| 344.86 | 2.74 | 2.74 |
| 384.74 | 4.30 | 4.30 |
| 488.20 | 5.36 | 5.36 |
| 448.49 | 6.21 | 6.21 |
| 375.51 | 5.49 | 5.49 |
| 443.02 | 4.17 | 4.17 |
| 297.75 | 3.47 | 3.47 |
| 424.50 | 3.66 | 3.66 |
| 444.90 | 3.31 | 3.31 |
| 468.53 | 3.76 | 3.76 |
| 273.09 | 2.74 | 2.74 |
| 373.80 | 4.84 | 4.84 |
| 425.96 | 4.59 | 4.59 |
| 498.07 | 4.70 | 4.70 |
| 439.54 | 2.20 | 2.20 |
| 449.53 | 3.98 | 3.98 |
| 459.01 | 5.28 | 5.28 |
| 421.57 | 4.38 | 4.38 |
| 462.43 | 4.40 | 4.40 |
| 387.36 | 1.68 | 1.68 |
| 338.32 | 2.90 | 2.90 |
| 309.95 | 1.36 | 1.36 |
| 425.36 | 5.93 | 5.93 |
| 281.70 | 4.10 | 4.10 |
| 376.75 | 2.38 | 2.38 |
| 380.58 | 5.01 | 5.01 |
| 420.43 | 3.40 | 3.40 |
| 282.25 | 1.95 | 1.95 |
| 339.40 | 3.75 | 3.75 |
| 297.22 | 1.64 | 1.64 |
| 444.04 | 5.08 | 5.08 |
| 337.42 | 2.96 | 2.96 |
| 485.07 | 5.36 | 5.36 |
| 376.43 | 4.50 | 4.50 |
| 217.27 | 2.87 | 2.87 |
| 237.31 | 3.29 | 3.29 |
| 259.29 | 3.55 | 3.55 |
| 341.84 | 3.61 | 3.61 |
| 375.34 | 3.76 | 3.76 |
| 256.31 | 2.29 | 2.29 |
| 420.85 | 3.54 | 3.54 |
| 396.45 | 3.05 | 3.05 |
| 403.51 | 4.67 | 4.67 |
| 207.66 | 2.90 | 2.90 |
| 318.37 | 3.52 | 3.52 |
| 237.26 | 3.11 | 3.11 |
| 290.37 | 3.94 | 3.94 |
| 504.41 | 2.66 | 2.66 |
| 421.57 | 4.29 | 4.29 |
| 345.83 | 3.42 | 3.42 |
| 317.56 | 3.09 | 3.09 |
| 227.27 | 1.30 | 1.30 |
| 342.14 | 1.92 | 1.92 |
| 418.49 | 2.06 | 2.06 |
| 372.17 | 3.40 | 3.40 |
| 293.28 | 1.64 | 1.64 |
| 361.81 | 2.94 | 2.94 |
| 351.42 | 2.90 | 2.90 |
| 468.45 | 4.93 | 4.93 |
| 482.88 | 4.98 | 4.98 |
| 471.03 | 4.72 | 4.72 |
| 541.63 | 2.65 | 2.65 |
| 264.28 | 3.12 | 3.12 |
| 268.29 | 3.69 | 3.69 |
| 353.17 | 1.54 | 1.54 |
| 459.91 | 3.53 | 3.53 |
| 319.41 | 3.39 | 3.39 |
| 363.79 | 3.36 | 3.36 |
| 492.62 | 3.15 | 3.15 |
| 450.54 | 3.62 | 3.62 |
| 413.35 | 3.29 | 3.29 |
| 501.45 | 4.52 | 4.52 |
| 330.84 | 2.43 | 2.43 |
| 418.25 | 4.95 | 4.95 |
| 383.24 | 1.96 | 1.96 |
| 564.47 | 5.39 | 5.39 |
| 293.33 | 4.50 | 4.50 |
| 363.48 | 5.71 | 5.71 |
| 405.84 | 3.50 | 3.50 |
| 484.50 | 5.80 | 5.80 |
| 444.36 | 4.06 | 4.06 |
| 438.02 | 4.28 | 4.28 |
| 321.25 | 1.57 | 1.57 |
| 383.24 | 1.92 | 1.92 |
| 388.41 | 2.77 | 2.77 |
| 476.00 | 4.36 | 4.36 |
| 277.66 | 3.74 | 3.74 |
| 285.69 | 2.55 | 2.55 |
| 364.27 | 2.85 | 2.85 |
| 406.83 | 3.15 | 3.15 |
| 371.42 | 4.16 | 4.16 |
| 350.29 | 3.64 | 3.64 |
| 355.31 | 3.59 | 3.59 |
| 434.45 | 3.71 | 3.71 |
| 315.74 | 3.16 | 3.16 |
| 395.39 | 1.77 | 1.77 |
| 522.41 | 4.32 | 4.32 |
| 426.95 | 4.89 | 4.89 |
| 307.35 | 2.29 | 2.29 |
| 542.70 | 3.67 | 3.67 |
| 305.21 | 2.55 | 2.55 |
| 396.56 | 4.69 | 4.69 |
| 456.56 | 3.68 | 3.68 |
| 423.58 | 3.20 | 3.20 |
| 297.14 | 3.41 | 3.41 |
| 274.28 | 2.65 | 2.65 |
| 297.27 | 2.91 | 2.91 |
| 385.98 | 4.50 | 4.50 |
| 471.58 | 3.72 | 3.72 |
| 321.33 | 3.08 | 3.08 |
| 358.35 | 2.67 | 2.67 |
| 277.75 | 3.52 | 3.52 |
| 279.30 | 3.04 | 3.04 |
| 372.38 | 2.50 | 2.50 |
| 381.26 | 1.89 | 1.89 |
| 452.51 | 4.71 | 4.71 |
| 510.43 | 4.86 | 4.86 |
| 281.27 | 3.25 | 3.25 |
| 264.27 | 1.22 | 1.22 |
| 296.24 | 3.01 | 3.01 |
| 187.24 | 1.81 | 1.81 |
| 364.32 | 3.95 | 3.95 |
| 277.32 | 3.47 | 3.47 |
| 395.53 | 2.71 | 2.71 |
| 392.40 | 2.38 | 2.38 |
| 304.18 | 2.00 | 2.00 |
| 468.54 | 1.46 | 1.46 |
| 342.85 | 1.25 | 1.25 |
| 382.42 | 4.13 | 4.13 |
| 312.87 | 2.71 | 2.71 |
| 346.37 | 3.57 | 3.57 |
| 405.46 | 3.37 | 3.37 |
| 291.78 | 3.91 | 3.91 |
| 337.40 | 4.47 | 4.47 |
| 263.12 | 2.17 | 2.17 |
| 304.20 | 2.83 | 2.83 |
| 501.77 | 4.42 | 4.42 |
| 496.41 | 4.55 | 4.55 |
| 356.81 | 3.72 | 3.72 |
| 467.32 | 3.76 | 3.76 |
| 223.66 | 2.60 | 2.60 |
| 507.25 | 4.68 | 4.68 |
| 579.23 | 5.46 | 5.46 |
| 422.49 | 3.16 | 3.16 |
| 540.13 | 5.77 | 5.77 |
| 342.32 | 1.71 | 1.71 |
| 316.30 | 2.96 | 2.96 |
| 412.87 | 3.95 | 3.95 |
| 548.68 | 5.01 | 5.01 |
| 378.82 | 3.24 | 3.24 |
| 364.79 | 2.85 | 2.85 |
| 332.30 | 2.57 | 2.57 |
| 288.33 | 3.33 | 3.33 |
| 414.40 | 3.13 | 3.13 |
| 294.76 | 3.26 | 3.26 |
| 388.42 | 2.36 | 2.36 |
| 594.15 | 5.70 | 5.70 |
| 459.51 | 5.31 | 5.31 |
| 358.35 | 3.34 | 3.34 |
| 459.36 | 2.67 | 2.67 |
| 527.65 | 3.56 | 3.56 |
| 333.37 | 2.75 | 2.75 |
| 436.49 | 3.07 | 3.07 |
| 447.37 | 3.04 | 3.04 |
| 281.78 | 2.32 | 2.32 |
| 416.41 | 4.78 | 4.78 |
| 446.99 | 2.30 | 2.30 |
| 317.26 | 1.61 | 1.61 |
| 427.55 | 5.04 | 5.04 |
| 333.26 | 1.66 | 1.66 |
| 439.00 | 4.30 | 4.30 |
| 289.25 | 1.72 | 1.72 |
| 444.43 | 2.76 | 2.76 |
| 447.47 | 2.28 | 2.28 |
| 235.67 | 2.13 | 2.13 |
| 287.30 | 2.47 | 2.47 |
| 402.46 | 2.69 | 2.69 |
| 401.55 | 2.93 | 2.93 |
| 354.19 | 3.18 | 3.18 |
| 284.28 | 3.04 | 3.04 |
| 376.39 | 2.53 | 2.53 |
| 289.32 | 2.73 | 2.73 |
| 317.30 | 2.33 | 2.33 |
| 360.41 | 2.19 | 2.19 |
| 278.18 | 2.14 | 2.14 |
| 299.24 | 2.70 | 2.70 |
| 345.31 | 2.39 | 2.39 |
| 272.29 | 2.89 | 2.89 |
| 351.71 | 2.70 | 2.70 |
| 402.50 | 3.21 | 3.21 |
| 286.32 | 3.20 | 3.20 |
| 295.39 | 2.32 | 2.32 |
| 324.30 | 2.74 | 2.74 |
| 291.31 | 2.70 | 2.70 |
| 350.33 | 1.68 | 1.68 |
| 302.29 | 2.06 | 2.06 |
| 332.34 | 1.54 | 1.54 |
| 364.41 | 2.16 | 2.16 |
| 395.01 | 2.53 | 2.53 |
| 343.39 | 3.36 | 3.36 |
| 379.37 | 2.96 | 2.96 |
| 276.28 | 1.82 | 1.82 |
| 371.38 | 2.08 | 2.08 |
| 324.30 | 2.78 | 2.78 |
| 370.21 | 3.47 | 3.47 |
| 354.19 | 3.18 | 3.18 |
| 293.30 | 2.63 | 2.63 |
| 313.27 | 1.91 | 1.91 |
| 317.26 | 1.48 | 1.48 |
| 355.17 | 2.58 | 2.58 |
| 320.82 | 2.84 | 2.84 |
| 303.27 | 2.03 | 2.03 |
| 286.29 | 2.55 | 2.55 |
| 346.82 | 2.93 | 2.93 |
| 435.28 | 2.79 | 2.79 |
| 332.79 | 2.53 | 2.53 |
| 305.31 | 1.84 | 1.84 |