Basic Information
ID: ALA1738565
Type: Functional
Description: PUBCHEM_BIOASSAY: HTS Assay for Allosteric Agonists of the Human D1 Dopamine Receptor: Primary Screen for Antagonists. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488989, AID488993, AID488995]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1738565
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.37 | 3.08 | 3.08 |
| 280.42 | 3.88 | 3.88 |
| 391.56 | 6.86 | 6.86 |
| 314.86 | 4.53 | 4.53 |
| 231.09 | 1.81 | 1.81 |
| 407.51 | 4.95 | 4.95 |
| 341.43 | 0.56 | 0.56 |
| 169.18 | 0.09 | 0.09 |
| 309.33 | 4.44 | 4.44 |
| 326.83 | 3.54 | 3.54 |
| 326.83 | 3.72 | 3.72 |
| 263.38 | 3.83 | 3.83 |
| 399.97 | 5.97 | 5.97 |
| 393.47 | 4.51 | 4.51 |
| 219.33 | 2.98 | 2.98 |
| 302.24 | 1.99 | 1.99 |
| 395.43 | 2.42 | 2.42 |
| 276.38 | 1.96 | 1.96 |
| 267.33 | 2.85 | 2.85 |
| 375.87 | 4.43 | 4.43 |
| 393.49 | 2.89 | 2.89 |
| 361.53 | 4.84 | 4.84 |
| 153.18 | 0.60 | 0.60 |
| 395.48 | 3.22 | 3.22 |
| 287.79 | 3.67 | 3.67 |
| 192.26 | 1.10 | 1.10 |
| 370.59 | 5.89 | 5.89 |
| 318.87 | 4.89 | 4.89 |
| 266.39 | 3.53 | 3.53 |
| 654.61 | 3.19 | 3.19 |
| 299.80 | 2.00 | 2.00 |
| 477.58 | 5.48 | 5.48 |
| 287.41 | 4.70 | 4.70 |
| 178.27 | 3.64 | 3.64 |
| 314.50 | 4.27 | 4.27 |
| 314.47 | 4.72 | 4.72 |
| 309.43 | 4.01 | 4.01 |
| 394.86 | 5.13 | 5.13 |
| 324.40 | 3.81 | 3.81 |
| 409.42 | 4.79 | 4.79 |
| 354.45 | 2.65 | 2.65 |
| 325.54 | 5.13 | 5.13 |
| 284.43 | 4.24 | 4.24 |
| 497.60 | 5.03 | 5.03 |
| 403.98 | 3.94 | 3.94 |
| 352.43 | 5.26 | 5.26 |
| 237.34 | 2.76 | 2.76 |
| 285.69 | 2.77 | 2.77 |
| 305.76 | 2.73 | 2.73 |
| 471.69 | 6.45 | 6.45 |
| 281.36 | 2.84 | 2.84 |
| 190.25 | 1.76 | 1.76 |
| 370.41 | 5.26 | 5.26 |
| 299.48 | 5.55 | 5.55 |
| 393.46 | 3.28 | 3.28 |
| 212.30 | 2.25 | 2.25 |
| 283.33 | 2.56 | 2.56 |
| 403.53 | 4.06 | 4.06 |
| 387.44 | 1.06 | 1.06 |
| 502.77 | 7.28 | 7.28 |
| 371.87 | 2.36 | 2.36 |
| 277.41 | 4.17 | 4.17 |
| 341.45 | 3.24 | 3.24 |
| 645.32 | 6.94 | 6.94 |
| 284.43 | 4.24 | 4.24 |
| 294.44 | 4.12 | 4.12 |
| 277.41 | 4.21 | 4.21 |
| 263.38 | 4.30 | 4.30 |
| 275.40 | 4.55 | 4.55 |
| 183.21 | 0.35 | 0.35 |
| 393.57 | 6.21 | 6.21 |
| 320.43 | 5.17 | 5.17 |
| 290.40 | 0.27 | 0.27 |
| 451.48 | 1.72 | 1.72 |
| 345.40 | 2.51 | 2.51 |
| 417.55 | 4.18 | 4.18 |
| 414.59 | 5.04 | 5.04 |
| 179.22 | 0.91 | 0.91 |
| 334.35 | 3.26 | 3.26 |
| 406.48 | 3.74 | 3.74 |
| 437.53 | 4.31 | 4.31 |
| 373.95 | 4.58 | 4.58 |
| 550.76 | 5.98 | 5.98 |
| 522.71 | 5.20 | 5.20 |
| 347.86 | 4.47 | 4.47 |
| 542.42 | 4.16 | 4.16 |
| 187.17 | 0.23 | 0.23 |
| 434.52 | 3.70 | 3.70 |
| 167.21 | 0.86 | 0.86 |
| 311.38 | 3.34 | 3.34 |
| 247.32 | 2.39 | 2.39 |
| 405.50 | 3.58 | 3.58 |
| 255.32 | 2.38 | 2.38 |
| 374.28 | 4.04 | 4.04 |
| 329.83 | 3.93 | 3.93 |
| 295.38 | 3.27 | 3.27 |
| 247.38 | 3.37 | 3.37 |
| 306.24 | 5.18 | 5.18 |
| 317.23 | 3.84 | 3.84 |
| 582.79 | 6.80 | 6.80 |
| 183.16 | 0.18 | 0.18 |
| 258.28 | 1.55 | 1.55 |
| 340.49 | 4.83 | 4.83 |
| 327.81 | 3.77 | 3.77 |
| 329.44 | 3.26 | 3.26 |
| 292.34 | 3.17 | 3.17 |
| 312.80 | 3.38 | 3.38 |
| 279.38 | 3.96 | 3.96 |
| 246.10 | 1.55 | 1.55 |
| 475.58 | 5.31 | 5.31 |
| 271.36 | 3.42 | 3.42 |
| 334.42 | 2.38 | 2.38 |
| 370.46 | 5.59 | 5.59 |
| 495.64 | 5.27 | 5.27 |
| 399.62 | 4.23 | 4.23 |
| 518.56 | 6.38 | 6.38 |
| 434.53 | 4.60 | 4.60 |
| 247.38 | 3.37 | 3.37 |
| 504.64 | -0.02 | -0.02 |
| 255.36 | 3.72 | 3.72 |
| 322.36 | 2.75 | 2.75 |
| 340.85 | 4.30 | 4.30 |
| 351.86 | 2.69 | 2.69 |
| 331.80 | 3.33 | 3.33 |
| 344.91 | 4.34 | 4.34 |
| 290.41 | 3.79 | 3.79 |
| 318.24 | 1.69 | 1.69 |
| 307.40 | 2.77 | 2.77 |
| 325.45 | 3.77 | 3.77 |
| 339.48 | 4.02 | 4.02 |
| 350.46 | 4.15 | 4.15 |
| 469.67 | 7.22 | 7.22 |
| 520.95 | 5.01 | 5.01 |
| 282.39 | 4.42 | 4.42 |
| 381.55 | 5.16 | 5.16 |
| 304.39 | 3.15 | 3.15 |
| 353.47 | 1.94 | 1.94 |
| 271.32 | 2.41 | 2.41 |
| 650.76 | 3.93 | 3.93 |
| 249.32 | 2.47 | 2.47 |
| 286.36 | 3.59 | 3.59 |
| 293.37 | 3.41 | 3.41 |
| 356.56 | 4.40 | 4.40 |
| 313.79 | 3.43 | 3.43 |
| 497.50 | 1.02 | 1.02 |
| 329.21 | -0.82 | -0.82 |
| 309.49 | 4.40 | 4.40 |
| 399.56 | 5.72 | 5.72 |
| 309.45 | 4.20 | 4.20 |
| 299.41 | 3.43 | 3.43 |
| 456.68 | 6.17 | 6.17 |
| 195.69 | 2.37 | 2.37 |
| 386.45 | 5.28 | 5.28 |
| 277.28 | 4.42 | 4.42 |
| 167.21 | 0.65 | 0.65 |
| 292.21 | 4.79 | 4.79 |
| 402.44 | 3.86 | 3.86 |
| 531.44 | 4.21 | 4.21 |
| 281.36 | 3.15 | 3.15 |
| 356.18 | 5.18 | 5.18 |
| 289.76 | 3.03 | 3.03 |
| 363.50 | 3.31 | 3.31 |
| 361.46 | 3.23 | 3.23 |
| 244.24 | 3.42 | 3.42 |
| 305.29 | 3.12 | 3.12 |
| 305.73 | 1.07 | 1.07 |
| 319.76 | 0.54 | 0.54 |
| 461.56 | 5.86 | 5.86 |
| 425.92 | 3.35 | 3.35 |
| 362.23 | 4.06 | 4.06 |
| 169.18 | 0.09 | 0.09 |
| 295.38 | 3.63 | 3.63 |
| 451.68 | 5.28 | 5.28 |
| 327.12 | 3.86 | 3.86 |
| 481.68 | 6.23 | 6.23 |
| 216.32 | 4.18 | 4.18 |
| 479.53 | 3.68 | 3.68 |
| 376.91 | 3.62 | 3.62 |
| 310.40 | 1.73 | 1.73 |
| 416.28 | 2.43 | 2.43 |
| 346.34 | 2.18 | 2.18 |
| 459.59 | 5.34 | 5.34 |
| 207.25 | 1.81 | 1.81 |
| 249.34 | 2.80 | 2.80 |
| 360.37 | 2.57 | 2.57 |
| 426.49 | 3.08 | 3.08 |
| 343.90 | 5.10 | 5.10 |
| 311.78 | 0.72 | 0.72 |
| 287.36 | 2.35 | 2.35 |
| 299.77 | 0.57 | 0.57 |
| 384.31 | 1.45 | 1.45 |
| 583.69 | 2.08 | 2.08 |
| 316.47 | 4.18 | 4.18 |
| 183.21 | 0.35 | 0.35 |
| 317.82 | 3.68 | 3.68 |
| 496.68 | 3.80 | 3.80 |
| 611.74 | 2.72 | 2.72 |
| 193.16 | 1.66 | 1.66 |
| 331.46 | 5.32 | 5.32 |
| 401.50 | 4.22 | 4.22 |
| 452.56 | 3.91 | 3.91 |
| 836.39 | -2.45 | -2.45 |
| 339.48 | 3.97 | 3.97 |
| 267.36 | 3.13 | 3.13 |
| 269.34 | 2.72 | 2.72 |
| 339.44 | 1.92 | 1.92 |
| 1031.00 | ||
| 322.50 | 4.39 | 4.39 |
| 523.63 | 5.53 | 5.53 |
| 349.40 | 3.65 | 3.65 |
| 290.45 | 4.75 | 4.75 |
| 339.44 | 3.25 | 3.25 |
| 370.42 | 2.45 | 2.45 |
| 325.45 | 3.14 | 3.14 |
| 315.87 | 5.19 | 5.19 |
| 276.61 | 3.51 | 3.51 |
| 491.65 | 5.96 | 5.96 |
| 541.63 | -0.98 | -0.98 |
| 230.34 | 2.75 | 2.75 |
| 230.31 | 2.68 | 2.68 |
| 489.59 | 5.17 | 5.17 |
| 467.42 | 3.81 | 3.81 |
| 392.55 | 5.74 | 5.74 |
| 481.48 | 3.98 | 3.98 |
| 394.49 | 4.04 | 4.04 |
| 379.44 | 3.89 | 3.89 |
| 186.26 | 2.01 | 2.01 |
| 350.47 | 5.16 | 5.16 |
| 473.30 | -1.02 | -1.02 |
| 340.85 | 2.69 | 2.69 |
| 201.22 | 1.64 | 1.64 |
| 419.35 | 3.74 | 3.74 |
| 508.45 | 5.68 | 5.68 |
| 249.36 | 2.74 | 2.74 |
| 261.35 | 2.74 | 2.74 |
| 231.34 | 2.91 | 2.91 |
| 466.67 | 5.22 | 5.22 |
| 427.67 | 5.01 | 5.01 |