Basic Information
ID: ALA1738579
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose Response confirmation of inhibitors of hexokinase domain containing I (HKDC1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493160, AID493190]
Format: BAO_0000019
Organism: Homo sapiens
Target: Putative hexokinase HKDC1(ALA1741200)
Document: ALA1201862
PubChem Source: AID:504729
Activity Charts
Bioactivity
Activity Types for Assay ALA1738579
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 347.33 | 0.31 | 0.31 |
| 505.46 | 4.18 | 4.18 |
| 173.17 | 0.75 | 0.75 |
| 310.40 | 1.73 | 1.73 |
| 168.15 | 0.20 | 0.20 |
| 186.21 | 1.34 | 1.34 |
| 317.28 | 3.80 | 3.80 |
| 862.75 | -1.10 | -1.10 |
| 381.38 | 3.49 | 3.49 |
| 424.51 | 3.42 | 3.42 |
| 487.94 | 4.50 | 4.50 |
| 357.81 | 0.68 | 0.68 |
| 369.76 | 3.27 | 3.27 |
| 453.56 | 3.31 | 3.31 |
| 410.43 | 2.70 | 2.70 |
| 327.38 | 3.75 | 3.75 |
| 318.76 | 1.71 | 1.71 |
| 335.34 | 2.69 | 2.69 |
| 336.34 | 3.09 | 3.09 |
| 282.34 | 3.09 | 3.09 |
| 386.28 | 2.32 | 2.32 |
| 371.42 | 3.48 | 3.48 |
| 453.56 | 3.40 | 3.40 |
| 302.29 | 3.56 | 3.56 |
| 358.38 | 2.13 | 2.13 |
| 434.45 | 3.43 | 3.43 |
| 362.42 | 3.15 | 3.15 |
| 297.31 | 1.87 | 1.87 |
| 398.47 | 3.62 | 3.62 |
| 350.33 | 3.56 | 3.56 |
| 317.39 | 0.85 | 0.85 |
| 276.30 | 3.08 | 3.08 |
| 305.38 | 3.41 | 3.41 |
| 431.54 | 4.45 | 4.45 |
| 417.51 | 4.14 | 4.14 |
| 418.72 | 1.31 | 1.31 |
| 409.52 | 4.56 | 4.56 |
| 356.43 | 3.15 | 3.15 |
| 532.05 | 3.60 | 3.60 |
| 369.41 | 2.38 | 2.38 |
| 493.39 | 4.68 | 4.68 |
| 338.36 | 4.40 | 4.40 |
| 327.38 | 3.58 | 3.58 |
| 862.75 | -1.10 | -1.10 |
| 377.42 | 2.97 | 2.97 |
| 862.75 | -1.10 | -1.10 |
| 364.41 | 2.49 | 2.49 |
| 403.44 | 4.11 | 4.11 |
| 353.43 | 4.20 | 4.20 |
| 394.46 | 3.45 | 3.45 |
| 354.79 | 3.82 | 3.82 |
| 313.38 | 3.65 | 3.65 |
| 374.27 | 1.20 | 1.20 |
| 435.26 | 3.27 | 3.27 |
| 240.26 | 2.56 | 2.56 |
| 523.60 | 3.33 | 3.33 |
| 501.59 | 5.05 | 5.05 |
| 302.36 | 2.24 | 2.24 |
| 402.54 | 6.48 | 6.48 |
| 392.41 | 3.68 | 3.68 |
| 349.37 | 2.94 | 2.94 |
| 241.29 | 2.28 | 2.28 |
| 410.74 | 4.54 | 4.54 |
| 396.49 | 4.34 | 4.34 |
| 315.35 | 3.37 | 3.37 |
| 435.00 | 4.83 | 4.83 |
| 383.88 | 0.94 | 0.94 |
| 494.60 | 4.07 | 4.07 |
| 267.28 | 2.47 | 2.47 |
| 410.45 | 1.48 | 1.48 |
| 350.76 | 4.52 | 4.52 |
| 396.49 | 4.17 | 4.17 |
| 262.27 | 2.65 | 2.65 |
| 374.19 | 3.90 | 3.90 |
| 316.31 | 0.62 | 0.62 |
| 363.39 | 3.33 | 3.33 |
| 523.46 | 4.23 | 4.23 |
| 540.67 | 4.09 | 4.09 |
| 447.39 | 5.07 | 5.07 |
| 438.53 | 3.86 | 3.86 |
| 381.53 | 5.15 | 5.15 |
| 360.37 | 2.01 | 2.01 |
| 331.47 | 4.08 | 4.08 |
| 280.41 | 2.78 | 2.78 |
| 530.37 | 3.48 | 3.48 |
| 263.30 | 2.58 | 2.58 |
| 316.31 | 2.25 | 2.25 |
| 498.61 | 5.19 | 5.19 |
| 243.26 | 1.13 | 1.13 |
| 414.59 | 4.49 | 4.49 |
| 319.74 | 3.40 | 3.40 |
| 514.33 | 4.56 | 4.56 |
| 302.79 | 3.94 | 3.94 |
| 356.38 | 3.52 | 3.52 |
| 426.37 | 4.17 | 4.17 |
| 383.43 | 2.77 | 2.77 |
| 419.48 | 3.53 | 3.53 |
| 348.32 | 2.40 | 2.40 |
| 371.42 | 3.48 | 3.48 |
| 332.31 | 3.57 | 3.57 |
| 316.31 | 3.87 | 3.87 |
| 312.76 | 3.88 | 3.88 |
| 584.70 | 2.88 | 2.88 |
| 350.37 | 3.18 | 3.18 |
| 545.27 | 4.26 | 4.26 |
| 371.78 | 4.11 | 4.11 |
| 323.39 | 3.92 | 3.92 |
| 386.27 | 2.55 | 2.55 |
| 322.15 | 4.57 | 4.57 |
| 370.50 | 2.74 | 2.74 |
| 329.38 | 3.35 | 3.35 |
| 333.44 | 3.10 | 3.10 |
| 451.53 | 4.61 | 4.61 |
| 394.38 | 2.53 | 2.53 |
| 368.51 | 3.13 | 3.13 |
| 365.01 | 4.22 | 4.22 |
| 376.41 | 1.58 | 1.58 |
| 331.80 | 3.70 | 3.70 |
| 484.58 | 4.88 | 4.88 |
| 353.85 | 5.16 | 5.16 |
| 457.58 | 3.13 | 3.13 |
| 440.51 | 4.97 | 4.97 |
| 362.35 | 2.70 | 2.70 |
| 382.45 | 3.29 | 3.29 |
| 415.88 | 4.57 | 4.57 |
| 473.92 | 4.11 | 4.11 |
| 330.34 | 4.17 | 4.17 |
| 338.32 | 2.91 | 2.91 |
| 400.48 | 3.00 | 3.00 |
| 367.88 | 1.10 | 1.10 |
| 321.33 | 3.08 | 3.08 |
| 277.75 | 3.52 | 3.52 |
| 228.25 | 2.22 | 2.22 |
| 313.31 | 4.83 | 4.83 |
| 355.44 | 4.83 | 4.83 |
| 423.90 | 4.18 | 4.18 |
| 224.30 | 1.22 | 1.22 |
| 339.40 | 4.01 | 4.01 |
| 325.39 | 3.77 | 3.77 |
| 415.23 | 2.90 | 2.90 |
| 343.43 | 4.78 | 4.78 |
| 539.66 | 4.75 | 4.75 |
| 291.78 | 3.91 | 3.91 |
| 431.45 | 4.30 | 4.30 |
| 179.20 | 1.99 | 1.99 |
| 348.32 | 2.40 | 2.40 |
| 338.33 | 3.31 | 3.31 |
| 362.35 | 2.70 | 2.70 |
| 319.74 | 2.31 | 2.31 |
| 270.29 | 1.74 | 1.74 |
| 436.42 | 4.26 | 4.26 |
| 424.20 | 3.08 | 3.08 |
| 469.56 | 2.55 | 2.55 |
| 277.28 | 3.26 | 3.26 |
| 350.41 | 2.41 | 2.41 |
| 364.78 | 3.60 | 3.60 |
| 505.00 | 5.23 | 5.23 |
| 308.34 | 2.74 | 2.74 |
| 250.21 | -0.24 | -0.24 |
| 284.70 | 3.60 | 3.60 |
| 506.97 | 5.43 | 5.43 |
| 315.35 | 2.67 | 2.67 |
| 274.24 | 1.85 | 1.85 |
| 277.71 | 2.43 | 2.43 |
| 198.17 | 0.17 | 0.17 |
| 424.53 | 5.16 | 5.16 |
| 286.37 | 4.49 | 4.49 |
| 317.35 | 2.55 | 2.55 |
| 313.36 | 3.45 | 3.45 |
| 237.26 | 2.57 | 2.57 |
| 323.42 | 3.94 | 3.94 |
| 268.07 | 1.71 | 1.71 |
| 351.20 | 3.43 | 3.43 |
| 296.17 | 4.83 | 4.83 |
| 277.28 | 2.38 | 2.38 |
| 300.31 | 3.74 | 3.74 |
| 273.29 | 2.50 | 2.50 |
| 438.53 | 3.98 | 3.98 |
| 311.77 | 3.35 | 3.35 |
| 268.32 | 3.19 | 3.19 |
| 323.29 | 2.82 | 2.82 |
| 455.54 | 2.71 | 2.71 |
| 454.57 | 4.92 | 4.92 |
| 255.23 | 1.12 | 1.12 |
| 326.37 | 3.47 | 3.47 |
| 478.48 | 3.02 | 3.02 |
| 316.27 | 1.04 | 1.04 |
| 315.35 | 3.54 | 3.54 |
| 305.76 | 2.63 | 2.63 |
| 253.06 | 1.03 | 1.03 |
| 1486.09 | ||
| 304.37 | 3.81 | 3.81 |
| 396.83 | 5.31 | 5.31 |
| 410.48 | 3.16 | 3.16 |
| 460.51 | 4.37 | 4.37 |
| 446.48 | 4.06 | 4.06 |
| 390.86 | 4.30 | 4.30 |
| 451.53 | 4.08 | 4.08 |
| 432.46 | 3.76 | 3.76 |
| 446.48 | 4.06 | 4.06 |
| 410.48 | 3.82 | 3.82 |
| 450.45 | 3.89 | 3.89 |
| 879.86 | 6.39 | 6.39 |
| 394.48 | 4.12 | 4.12 |
| 460.51 | 4.32 | 4.32 |
| 388.41 | -0.33 | -0.33 |
| 291.31 | 3.99 | 3.99 |
| 371.35 | 0.75 | 0.75 |
| 293.28 | 2.60 | 2.60 |
| 460.51 | 4.32 | 4.32 |
| 452.51 | 3.91 | 3.91 |
| 288.33 | 1.81 | 1.81 |
| 474.54 | 4.68 | 4.68 |
| 490.49 | 3.54 | 3.54 |
| 309.12 | 2.10 | 2.10 |