Basic Information
ID: ALA1738612
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose Response screen for agonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule agonists hits of the APJ receptor. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2520, AID2580]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1738612
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 303.77 | 4.08 | 4.08 |
| 330.43 | 3.92 | 3.92 |
| 477.59 | 3.00 | 3.00 |
| 456.55 | 4.82 | 4.82 |
| 631.22 | 4.66 | 4.66 |
| 599.22 | 5.26 | 5.26 |
| 270.40 | 2.98 | 2.98 |
| 437.56 | 4.80 | 4.80 |
| 344.44 | 3.15 | 3.15 |
| 404.47 | 3.52 | 3.52 |
| 557.72 | 4.58 | 4.58 |
| 589.16 | 4.78 | 4.78 |
| 492.63 | 4.42 | 4.42 |
| 616.05 | 5.22 | 5.22 |
| 450.61 | 3.98 | 3.98 |
| 402.55 | 4.08 | 4.08 |
| 453.56 | 3.83 | 3.83 |
| 498.59 | 5.12 | 5.12 |
| 368.50 | 4.32 | 4.32 |
| 476.58 | 4.04 | 4.04 |
| 327.37 | 2.47 | 2.47 |
| 472.55 | 3.26 | 3.26 |
| 585.20 | 4.95 | 4.95 |
| 468.60 | 4.02 | 4.02 |
| 478.60 | 4.11 | 4.11 |
| 296.80 | 4.38 | 4.38 |
| 603.21 | 5.11 | 5.11 |
| 362.45 | 4.00 | 4.00 |
| 693.93 | 4.76 | 4.76 |
| 459.58 | 3.87 | 3.87 |
| 601.19 | 4.65 | 4.65 |
| 379.46 | 4.25 | 4.25 |
| 493.52 | 4.11 | 4.11 |
| 585.20 | 4.95 | 4.95 |
| 324.39 | 2.36 | 2.36 |
| 256.37 | 2.59 | 2.59 |
| 459.51 | 6.77 | 6.77 |
| 426.47 | 2.92 | 2.92 |
| 351.36 | 4.16 | 4.16 |
| 268.38 | 2.76 | 2.76 |
| 264.31 | 1.67 | 1.67 |
| 492.63 | 4.42 | 4.42 |
| 615.22 | 5.04 | 5.04 |
| 362.34 | 4.76 | 4.76 |
| 330.48 | 3.85 | 3.85 |
| 377.51 | 3.34 | 3.34 |
| 442.54 | 3.35 | 3.35 |
| 495.58 | 3.14 | 3.14 |
| 615.22 | 5.04 | 5.04 |
| 483.59 | 4.50 | 4.50 |
| 535.05 | 4.79 | 4.79 |
| 385.50 | 4.38 | 4.38 |
| 630.62 | 4.01 | 4.01 |
| 344.41 | 3.54 | 3.54 |
| 488.59 | 4.12 | 4.12 |
| 405.56 | 4.12 | 4.12 |
| 348.41 | 3.54 | 3.54 |
| 459.51 | 6.77 | 6.77 |
| 294.27 | 3.44 | 3.44 |
| 601.19 | 4.65 | 4.65 |
| 589.16 | 4.78 | 4.78 |
| 480.52 | 5.36 | 5.36 |
| 499.53 | 6.20 | 6.20 |
| 322.15 | 4.57 | 4.57 |
| 498.59 | 4.98 | 4.98 |
| 390.44 | 3.13 | 3.13 |
| 509.68 | 3.79 | 3.79 |
| 599.22 | 5.20 | 5.20 |
| 436.63 | 5.80 | 5.80 |
| 415.50 | 3.87 | 3.87 |
| 391.54 | 3.59 | 3.59 |
| 368.50 | 4.32 | 4.32 |
| 351.41 | 4.02 | 4.02 |
| 319.38 | 2.86 | 2.86 |
| 335.41 | 4.31 | 4.31 |
| 451.94 | 4.73 | 4.73 |
| 451.94 | 4.73 | 4.73 |