Basic Information
ID: ALA1738632
Type: Functional
Description: PUBCHEM_BIOASSAY: SAR analysis of compounds that are cytotoxic to HEK293 revised. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1566, AID1575, AID1578, AID1579, AID1848, AID1849, AID2001, AID2333, AID2466, AID2469, AID2475, AID2483, AID2798, AID2799, AID2800, AID2801]
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1738632
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 283.42 | 3.77 | 3.77 |
| 308.29 | 3.71 | 3.71 |
| 225.32 | 4.27 | 4.27 |
| 307.40 | 3.64 | 3.64 |
| 310.38 | 2.19 | 2.19 |
| 265.19 | 0.64 | 0.64 |
| 531.43 | 3.78 | 3.78 |
| 353.42 | 3.88 | 3.88 |
| 500.96 | 3.58 | 3.58 |
| 255.35 | 3.86 | 3.86 |
| 343.22 | 4.27 | 4.27 |
| 366.44 | 2.25 | 2.25 |
| 347.46 | 4.28 | 4.28 |
| 335.11 | 4.68 | 4.68 |
| 524.40 | 4.64 | 4.64 |
| 257.72 | 3.32 | 3.32 |
| 303.34 | 1.86 | 1.86 |
| 478.55 | 2.57 | 2.57 |
| 345.42 | 3.64 | 3.64 |
| 273.32 | 1.86 | 1.86 |
| 397.62 | 3.75 | 3.75 |
| 435.53 | 5.07 | 5.07 |
| 337.41 | 3.68 | 3.68 |
| 331.37 | 2.50 | 2.50 |
| 381.43 | 3.30 | 3.30 |
| 362.39 | 4.66 | 4.66 |
| 374.42 | 3.82 | 3.82 |
| 351.79 | 4.58 | 4.58 |
| 299.76 | 3.70 | 3.70 |
| 492.35 | 5.15 | 5.15 |
| 393.49 | 4.79 | 4.79 |
| 317.27 | 5.37 | 5.37 |
| 338.37 | 2.55 | 2.55 |
| 405.47 | 3.85 | 3.85 |
| 458.34 | 4.76 | 4.76 |
| 345.66 | 3.93 | 3.93 |
| 356.47 | 4.81 | 4.81 |
| 335.81 | 4.23 | 4.23 |
| 321.42 | 3.88 | 3.88 |
| 460.00 | 3.54 | 3.54 |
| 325.25 | 3.33 | 3.33 |
| 494.57 | 3.34 | 3.34 |
| 399.49 | 4.46 | 4.46 |
| 315.40 | 2.78 | 2.78 |
| 458.54 | 2.79 | 2.79 |
| 457.56 | 3.46 | 3.46 |
| 318.41 | 4.37 | 4.37 |
| 331.38 | 4.24 | 4.24 |
| 354.79 | 3.82 | 3.82 |
| 252.27 | 3.47 | 3.47 |
| 486.94 | 3.44 | 3.44 |
| 360.46 | 3.45 | 3.45 |
| 429.50 | 2.80 | 2.80 |
| 359.31 | 4.54 | 4.54 |
| 387.89 | 4.97 | 4.97 |
| 390.42 | 1.20 | 1.20 |
| 472.36 | 5.07 | 5.07 |
| 451.58 | 1.94 | 1.94 |
| 400.50 | 2.86 | 2.86 |
| 299.76 | 3.70 | 3.70 |
| 331.39 | 3.55 | 3.55 |
| 413.43 | 1.88 | 1.88 |
| 324.43 | 4.43 | 4.43 |
| 354.37 | 3.81 | 3.81 |
| 369.44 | 3.96 | 3.96 |
| 542.06 | 4.82 | 4.82 |
| 406.46 | 2.75 | 2.75 |
| 428.60 | 2.62 | 2.62 |
| 247.32 | 3.12 | 3.12 |
| 492.50 | 4.23 | 4.23 |
| 318.31 | 1.76 | 1.76 |
| 360.40 | 3.43 | 3.43 |
| 313.79 | 4.09 | 4.09 |
| 399.54 | 4.60 | 4.60 |
| 442.50 | 3.38 | 3.38 |
| 286.36 | 2.89 | 2.89 |
| 491.61 | 3.52 | 3.52 |
| 287.34 | 2.16 | 2.16 |
| 363.47 | 3.34 | 3.34 |
| 394.27 | 3.55 | 3.55 |
| 441.55 | 2.70 | 2.70 |
| 285.74 | 3.09 | 3.09 |
| 365.48 | 4.09 | 4.09 |
| 333.42 | 4.32 | 4.32 |
| 289.22 | 3.43 | 3.43 |
| 281.32 | 2.51 | 2.51 |
| 400.91 | 2.86 | 2.86 |
| 318.42 | 3.55 | 3.55 |
| 450.52 | 4.09 | 4.09 |
| 365.84 | 4.20 | 4.20 |
| 415.47 | 4.84 | 4.84 |
| 423.65 | 3.28 | 3.28 |
| 385.33 | 3.74 | 3.74 |
| 523.56 | 4.03 | 4.03 |
| 263.73 | 2.55 | 2.55 |
| 335.81 | 4.23 | 4.23 |
| 445.56 | 3.27 | 3.27 |
| 455.58 | 2.89 | 2.89 |
| 352.39 | 2.94 | 2.94 |
| 421.45 | 4.19 | 4.19 |
| 377.49 | 3.71 | 3.71 |
| 387.39 | 5.03 | 5.03 |
| 376.41 | 5.15 | 5.15 |
| 475.61 | 4.28 | 4.28 |
| 466.42 | 5.82 | 5.82 |
| 297.36 | 2.86 | 2.86 |
| 433.56 | 2.64 | 2.64 |
| 453.93 | 3.54 | 3.54 |
| 374.40 | 3.47 | 3.47 |
| 445.36 | 3.12 | 3.12 |
| 377.40 | 4.71 | 4.71 |
| 269.30 | 2.18 | 2.18 |
| 279.34 | 3.43 | 3.43 |
| 394.46 | 3.84 | 3.84 |
| 349.46 | 2.72 | 2.72 |
| 560.68 | 3.07 | 3.07 |
| 391.52 | 4.02 | 4.02 |
| 363.47 | 3.34 | 3.34 |
| 265.32 | 3.04 | 3.04 |
| 287.75 | 3.35 | 3.35 |
| 334.22 | 4.39 | 4.39 |
| 481.62 | 2.55 | 2.55 |
| 357.36 | 2.69 | 2.69 |
| 359.41 | 4.58 | 4.58 |
| 305.36 | 3.48 | 3.48 |
| 330.36 | 3.45 | 3.45 |
| 470.60 | 4.46 | 4.46 |
| 479.60 | 3.44 | 3.44 |
| 412.50 | 4.24 | 4.24 |
| 370.48 | 2.72 | 2.72 |
| 272.33 | 2.58 | 2.58 |
| 307.76 | 2.51 | 2.51 |
| 377.49 | 3.59 | 3.59 |
| 253.33 | 3.31 | 3.31 |
| 494.04 | 4.12 | 4.12 |
| 445.47 | 4.02 | 4.02 |
| 333.43 | 4.04 | 4.04 |
| 329.42 | 3.90 | 3.90 |
| 249.71 | 2.24 | 2.24 |
| 377.49 | 3.82 | 3.82 |
| 436.94 | 4.53 | 4.53 |
| 367.45 | 3.26 | 3.26 |
| 480.01 | 3.81 | 3.81 |
| 339.37 | 2.55 | 2.55 |
| 338.39 | 1.12 | 1.12 |
| 360.43 | 4.64 | 4.64 |
| 317.35 | 3.93 | 3.93 |
| 255.25 | 2.45 | 2.45 |
| 456.57 | 2.73 | 2.73 |
| 431.49 | 3.31 | 3.31 |
| 467.59 | 3.09 | 3.09 |
| 399.86 | 4.34 | 4.34 |
| 442.59 | 2.43 | 2.43 |
| 426.49 | 4.03 | 4.03 |
| 372.38 | 3.87 | 3.87 |
| 356.45 | 3.58 | 3.58 |
| 306.15 | 3.61 | 3.61 |
| 321.35 | 3.14 | 3.14 |
| 343.60 | 3.66 | 3.66 |
| 313.79 | 4.09 | 4.09 |
| 330.32 | 3.27 | 3.27 |
| 271.35 | 3.31 | 3.31 |
| 436.49 | 2.76 | 2.76 |
| 308.29 | 3.71 | 3.71 |
| 414.51 | 4.67 | 4.67 |
| 386.50 | 4.90 | 4.90 |
| 296.37 | 3.46 | 3.46 |
| 352.44 | 2.25 | 2.25 |
| 331.39 | 3.59 | 3.59 |
| 307.76 | 3.02 | 3.02 |
| 499.98 | 4.04 | 4.04 |
| 382.48 | 2.05 | 2.05 |
| 381.28 | 5.32 | 5.32 |
| 409.51 | 4.39 | 4.39 |
| 274.32 | 2.24 | 2.24 |
| 420.30 | 4.09 | 4.09 |
| 489.60 | 5.04 | 5.04 |
| 367.45 | 4.08 | 4.08 |
| 393.47 | 4.31 | 4.31 |
| 260.30 | 2.13 | 2.13 |
| 457.53 | 3.98 | 3.98 |
| 489.64 | 4.67 | 4.67 |
| 301.37 | 3.32 | 3.32 |
| 380.45 | 3.72 | 3.72 |
| 376.89 | 5.15 | 5.15 |
| 312.76 | 4.03 | 4.03 |
| 379.82 | 5.13 | 5.13 |
| 447.49 | 4.51 | 4.51 |
| 267.40 | 5.26 | 5.26 |
| 433.96 | 3.15 | 3.15 |
| 444.51 | 2.40 | 2.40 |
| 391.86 | 5.00 | 5.00 |
| 372.47 | 4.51 | 4.51 |
| 257.72 | 3.32 | 3.32 |
| 372.47 | 4.90 | 4.90 |
| 399.52 | 2.50 | 2.50 |
| 396.28 | 5.64 | 5.64 |
| 436.49 | 3.96 | 3.96 |
| 356.77 | 4.67 | 4.67 |
| 353.40 | 2.86 | 2.86 |
| 349.80 | 2.89 | 2.89 |
| 445.50 | 4.23 | 4.23 |
| 388.54 | 5.22 | 5.22 |
| 375.86 | 5.30 | 5.30 |
| 440.91 | 4.60 | 4.60 |
| 415.50 | 3.92 | 3.92 |
| 410.50 | 1.98 | 1.98 |
| 461.49 | 5.40 | 5.40 |
| 337.47 | 3.99 | 3.99 |
| 424.53 | 2.37 | 2.37 |
| 394.29 | 4.59 | 4.59 |
| 411.33 | 5.80 | 5.80 |
| 324.42 | 3.93 | 3.93 |
| 329.38 | 2.54 | 2.54 |
| 449.92 | 4.87 | 4.87 |
| 339.37 | 2.55 | 2.55 |
| 447.99 | 3.54 | 3.54 |
| 421.34 | 5.26 | 5.26 |
| 390.91 | 5.19 | 5.19 |
| 349.84 | 4.48 | 4.48 |
| 379.44 | 4.22 | 4.22 |
| 425.55 | 2.89 | 2.89 |
| 349.39 | 3.26 | 3.26 |
| 426.44 | 5.40 | 5.40 |
| 401.45 | 4.00 | 4.00 |
| 349.84 | 4.32 | 4.32 |
| 358.44 | 4.51 | 4.51 |
| 380.47 | 2.34 | 2.34 |
| 441.55 | 2.70 | 2.70 |
| 430.49 | 2.01 | 2.01 |
| 429.54 | 2.50 | 2.50 |
| 456.52 | 2.40 | 2.40 |
| 396.28 | 5.64 | 5.64 |
| 367.86 | 5.05 | 5.05 |
| 419.93 | 2.76 | 2.76 |
| 361.49 | 4.37 | 4.37 |
| 367.88 | 5.26 | 5.26 |
| 380.26 | 4.34 | 4.34 |
| 354.39 | 3.37 | 3.37 |
| 376.89 | 5.15 | 5.15 |
| 427.53 | 2.31 | 2.31 |
| 433.96 | 3.15 | 3.15 |
| 400.52 | 4.94 | 4.94 |
| 347.41 | 4.05 | 4.05 |
| 312.39 | 4.06 | 4.06 |
| 455.58 | 3.09 | 3.09 |
| 367.86 | 5.05 | 5.05 |
| 346.41 | 4.64 | 4.64 |
| 351.79 | 4.58 | 4.58 |
| 439.58 | 3.19 | 3.19 |
| 310.42 | 2.65 | 2.65 |
| 338.45 | 4.32 | 4.32 |
| 340.49 | 4.65 | 4.65 |
| 372.38 | 3.51 | 3.51 |
| 391.45 | 3.57 | 3.57 |
| 342.74 | 4.36 | 4.36 |
| 386.50 | 4.90 | 4.90 |
| 361.83 | 4.99 | 4.99 |
| 428.53 | 4.72 | 4.72 |
| 251.29 | 2.50 | 2.50 |
| 409.15 | 2.78 | 2.78 |
| 422.34 | 5.06 | 5.06 |
| 341.37 | 3.37 | 3.37 |
| 374.51 | 5.22 | 5.22 |
| 445.97 | 3.15 | 3.15 |
| 339.37 | 2.85 | 2.85 |
| 327.82 | 4.33 | 4.33 |
| 453.56 | 2.70 | 2.70 |
| 371.48 | 4.57 | 4.57 |
| 339.37 | 2.55 | 2.55 |
| 470.55 | 2.79 | 2.79 |
| 406.47 | 3.95 | 3.95 |
| 433.49 | 4.06 | 4.06 |
| 404.90 | 5.06 | 5.06 |
| 436.54 | 2.37 | 2.37 |
| 401.45 | 4.21 | 4.21 |
| 413.54 | 2.80 | 2.80 |
| 367.88 | 5.26 | 5.26 |
| 385.51 | 4.56 | 4.56 |
| 418.50 | 4.25 | 4.25 |
| 375.86 | 4.92 | 4.92 |
| 444.51 | 2.40 | 2.40 |
| 386.84 | 4.86 | 4.86 |
| 422.51 | 3.74 | 3.74 |
| 342.40 | 4.08 | 4.08 |