Basic Information
ID: ALA1738640
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS small molecule inhibitors of tim10-1: a luminescent tim23-1 yeast counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463190, AID463194, AID493003]
Organism: Saccharomyces cerevisiae S288c
Activity Charts
Bioactivity
Activity Types for Assay ALA1738640
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 274.18 | ||
| 331.35 | 2.62 | 2.62 |
| 346.42 | 4.25 | 4.25 |
| 406.46 | 2.13 | 2.13 |
| 426.35 | 5.37 | 5.37 |
| 333.39 | 3.54 | 3.54 |
| 545.93 | 5.49 | 5.49 |
| 304.85 | 4.26 | 4.26 |
| 422.46 | 3.24 | 3.24 |
| 188.19 | 0.94 | 0.94 |
| 353.47 | 3.00 | 3.00 |
| 421.38 | 1.34 | 1.34 |
| 371.80 | 3.98 | 3.98 |
| 405.52 | 5.32 | 5.32 |
| 374.46 | 2.80 | 2.80 |
| 423.25 | 2.31 | 2.31 |
| 394.46 | 3.21 | 3.21 |
| 541.92 | 4.18 | 4.18 |
| 260.34 | 3.03 | 3.03 |
| 377.24 | 5.93 | 5.93 |
| 349.18 | 2.94 | 2.94 |
| 329.43 | 4.19 | 4.19 |
| 296.32 | 3.45 | 3.45 |
| 398.44 | 2.97 | 2.97 |
| 383.23 | 3.68 | 3.68 |
| 466.35 | 4.05 | 4.05 |
| 279.30 | 2.94 | 2.94 |
| 260.34 | 5.17 | 5.17 |
| 314.30 | 2.11 | 2.11 |
| 334.76 | 2.83 | 2.83 |
| 276.37 | 4.04 | 4.04 |
| 401.47 | 3.78 | 3.78 |
| 386.41 | 2.74 | 2.74 |
| 234.25 | 1.07 | 1.07 |
| 305.33 | 2.73 | 2.73 |
| 248.28 | 1.46 | 1.46 |
| 315.17 | 3.34 | 3.34 |
| 327.34 | 2.87 | 2.87 |
| 431.90 | 3.70 | 3.70 |
| 367.30 | 5.65 | 5.65 |
| 378.51 | 4.21 | 4.21 |
| 353.45 | 5.20 | 5.20 |
| 334.37 | 1.44 | 1.44 |
| 350.42 | 3.83 | 3.83 |
| 261.33 | 4.57 | 4.57 |
| 267.28 | 2.89 | 2.89 |
| 417.83 | 2.80 | 2.80 |
| 451.00 | 5.46 | 5.46 |
| 414.57 | 3.07 | 3.07 |
| 373.79 | 4.40 | 4.40 |
| 370.43 | 3.32 | 3.32 |
| 445.52 | 3.54 | 3.54 |
| 401.48 | 6.00 | 6.00 |
| 289.29 | 3.35 | 3.35 |
| 491.54 | 4.00 | 4.00 |
| 430.51 | 3.14 | 3.14 |
| 338.79 | 4.37 | 4.37 |
| 276.33 | 4.20 | 4.20 |
| 297.27 | 2.61 | 2.61 |
| 340.77 | 3.33 | 3.33 |
| 298.32 | 2.43 | 2.43 |
| 385.84 | 2.74 | 2.74 |
| 274.32 | 4.84 | 4.84 |
| 330.82 | 4.07 | 4.07 |
| 365.61 | 4.73 | 4.73 |
| 368.46 | 4.52 | 4.52 |
| 476.50 | 4.11 | 4.11 |
| 394.46 | 3.29 | 3.29 |
| 422.36 | 3.94 | 3.94 |
| 347.37 | 2.16 | 2.16 |
| 280.75 | 2.31 | 2.31 |
| 349.45 | 5.19 | 5.19 |
| 338.84 | 4.24 | 4.24 |
| 365.35 | 4.12 | 4.12 |
| 341.32 | 2.45 | 2.45 |
| 406.01 | 2.72 | 2.72 |
| 379.45 | 2.70 | 2.70 |
| 328.33 | 4.74 | 4.74 |
| 336.05 | 3.15 | 3.15 |
| 425.36 | 4.32 | 4.32 |
| 298.30 | 2.41 | 2.41 |
| 325.46 | 3.94 | 3.94 |
| 316.79 | 3.74 | 3.74 |
| 266.37 | 4.86 | 4.86 |
| 371.65 | 4.46 | 4.46 |
| 408.23 | 5.05 | 5.05 |
| 322.27 | 1.20 | 1.20 |
| 257.25 | 3.39 | 3.39 |
| 264.24 | 1.65 | 1.65 |
| 245.23 | 1.29 | 1.29 |
| 333.42 | 4.38 | 4.38 |
| 328.33 | 4.74 | 4.74 |
| 503.08 | 5.74 | 5.74 |
| 337.15 | 3.28 | 3.28 |
| 332.40 | 2.82 | 2.82 |
| 304.73 | 2.83 | 2.83 |
| 321.41 | 4.30 | 4.30 |
| 305.71 | 3.46 | 3.46 |
| 369.42 | 4.38 | 4.38 |
| 381.50 | 3.91 | 3.91 |
| 405.57 | 6.81 | 6.81 |
| 461.52 | 3.99 | 3.99 |
| 389.76 | 4.64 | 4.64 |
| 297.14 | 3.43 | 3.43 |
| 411.52 | 6.19 | 6.19 |
| 535.05 | 4.79 | 4.79 |
| 601.19 | 5.04 | 5.04 |
| 372.22 | 4.59 | 4.59 |
| 278.31 | 3.28 | 3.28 |
| 357.84 | 4.03 | 4.03 |
| 416.52 | 4.56 | 4.56 |
| 298.88 | 4.87 | 4.87 |
| 263.28 | 2.61 | 2.61 |
| 321.42 | 4.58 | 4.58 |
| 309.15 | 3.68 | 3.68 |
| 299.33 | 3.60 | 3.60 |
| 769.90 | 5.31 | 5.31 |
| 323.37 | 2.60 | 2.60 |
| 332.79 | 3.09 | 3.09 |
| 278.32 | 4.50 | 4.50 |
| 364.43 | 4.03 | 4.03 |
| 317.78 | 1.38 | 1.38 |
| 331.38 | 4.19 | 4.19 |
| 426.35 | 5.51 | 5.51 |
| 318.33 | 4.53 | 4.53 |
| 384.23 | 3.12 | 3.12 |
| 342.36 | 4.31 | 4.31 |
| 323.23 | 3.76 | 3.76 |
| 344.37 | 2.50 | 2.50 |
| 280.29 | 3.52 | 3.52 |
| 425.46 | 2.67 | 2.67 |
| 462.15 | 4.66 | 4.66 |
| 327.45 | 3.13 | 3.13 |
| 323.87 | 3.79 | 3.79 |
| 300.79 | 3.27 | 3.27 |
| 291.33 | 2.22 | 2.22 |
| 275.42 | 2.99 | 2.99 |
| 305.45 | 3.94 | 3.94 |
| 288.25 | 2.16 | 2.16 |
| 374.83 | 4.65 | 4.65 |
| 422.53 | 4.74 | 4.74 |
| 342.24 | 4.77 | 4.77 |
| 437.32 | 4.57 | 4.57 |
| 277.30 | 1.83 | 1.83 |
| 323.46 | 4.41 | 4.41 |