Basic Information
ID: ALA1738670
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504462, AID504475]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1738670
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 278.44 | 5.66 | 5.66 |
| 310.40 | 5.19 | 5.19 |
| 309.15 | 4.88 | 4.88 |
| 208.22 | 2.73 | 2.73 |
| 223.23 | 2.31 | 2.31 |
| 384.45 | 6.46 | 6.46 |
| 261.71 | 4.09 | 4.09 |
| 294.15 | 2.99 | 2.99 |
| 416.55 | 3.73 | 3.73 |
| 310.40 | 1.73 | 1.73 |
| 372.38 | 4.25 | 4.25 |
| 287.17 | 4.56 | 4.56 |
| 324.41 | 4.54 | 4.54 |
| 506.48 | 6.09 | 6.09 |
| 360.64 | 5.10 | 5.10 |
| 324.81 | 4.79 | 4.79 |
| 207.19 | -1.32 | -1.32 |
| 309.33 | 1.03 | 1.03 |
| 374.51 | 4.02 | 4.02 |
| 290.75 | 1.76 | 1.76 |
| 329.36 | 4.73 | 4.73 |
| 544.99 | -0.35 | -0.35 |
| 381.48 | 4.74 | 4.74 |
| 364.40 | 3.95 | 3.95 |
| 428.87 | 4.00 | 4.00 |
| 425.52 | 5.48 | 5.48 |
| 330.69 | 2.67 | 2.67 |
| 466.73 | 4.56 | 4.56 |
| 313.38 | 3.95 | 3.95 |
| 430.46 | 3.97 | 3.97 |
| 457.49 | 3.43 | 3.43 |
| 377.50 | 3.02 | 3.02 |
| 433.58 | 5.38 | 5.38 |
| 246.33 | 3.92 | 3.92 |
| 524.40 | 4.64 | 4.64 |
| 476.55 | 5.02 | 5.02 |
| 406.94 | 3.37 | 3.37 |
| 292.71 | 2.23 | 2.23 |
| 475.57 | 5.94 | 5.94 |
| 350.46 | 4.11 | 4.11 |
| 456.96 | 4.85 | 4.85 |
| 351.83 | 4.70 | 4.70 |
| 321.38 | 2.70 | 2.70 |
| 399.26 | 4.25 | 4.25 |
| 235.25 | -0.67 | -0.67 |
| 331.78 | 4.46 | 4.46 |
| 363.37 | 3.44 | 3.44 |
| 457.33 | 3.66 | 3.66 |
| 462.51 | 4.81 | 4.81 |
| 390.49 | 3.42 | 3.42 |
| 321.25 | 4.32 | 4.32 |
| 371.85 | 3.89 | 3.89 |
| 300.36 | 4.48 | 4.48 |
| 323.13 | 4.49 | 4.49 |
| 477.01 | 5.27 | 5.27 |
| 434.52 | 5.67 | 5.67 |
| 417.63 | 4.03 | 4.03 |
| 348.79 | 4.88 | 4.88 |
| 274.36 | 3.40 | 3.40 |
| 366.44 | 5.24 | 5.24 |
| 253.68 | 4.23 | 4.23 |
| 499.79 | 5.34 | 5.34 |
| 427.51 | 2.66 | 2.66 |
| 385.92 | 4.64 | 4.64 |
| 412.47 | 5.05 | 5.05 |
| 350.87 | 4.84 | 4.84 |
| 306.46 | 3.89 | 3.89 |
| 546.57 | 5.70 | 5.70 |
| 376.48 | 5.60 | 5.60 |
| 260.36 | 4.40 | 4.40 |
| 403.46 | 4.57 | 4.57 |
| 387.88 | 5.42 | 5.42 |
| 475.55 | 4.29 | 4.29 |
| 284.14 | 3.53 | 3.53 |
| 388.83 | 5.26 | 5.26 |
| 351.49 | 4.53 | 4.53 |
| 424.83 | 5.81 | 5.81 |
| 470.53 | 3.06 | 3.06 |
| 369.83 | 5.34 | 5.34 |
| 488.46 | 4.66 | 4.66 |
| 476.55 | 5.02 | 5.02 |
| 371.36 | 5.21 | 5.21 |
| 364.86 | 5.45 | 5.45 |
| 485.06 | 4.83 | 4.83 |
| 457.27 | 5.04 | 5.04 |
| 326.34 | 4.48 | 4.48 |
| 405.54 | 4.26 | 4.26 |
| 385.51 | 3.72 | 3.72 |
| 368.44 | 4.52 | 4.52 |
| 365.40 | 4.34 | 4.34 |
| 314.80 | 4.77 | 4.77 |
| 336.44 | 4.67 | 4.67 |
| 325.87 | 3.55 | 3.55 |
| 417.45 | 3.75 | 3.75 |
| 451.94 | 4.25 | 4.25 |
| 292.32 | 1.48 | 1.48 |
| 370.41 | 4.59 | 4.59 |
| 348.15 | 4.94 | 4.94 |
| 318.13 | 3.96 | 3.96 |
| 346.27 | 2.07 | 2.07 |
| 463.56 | 4.94 | 4.94 |
| 361.24 | 3.16 | 3.16 |
| 329.49 | 5.03 | 5.03 |
| 452.15 | 4.67 | 4.67 |
| 388.28 | 6.16 | 6.16 |
| 357.42 | 2.78 | 2.78 |
| 437.30 | 3.30 | 3.30 |
| 404.44 | 4.44 | 4.44 |
| 236.27 | 3.68 | 3.68 |
| 389.46 | 4.25 | 4.25 |
| 352.84 | 3.43 | 3.43 |
| 317.39 | 4.68 | 4.68 |
| 351.19 | 2.98 | 2.98 |
| 368.86 | 4.55 | 4.55 |
| 354.50 | 4.37 | 4.37 |
| 473.91 | 5.69 | 5.69 |
| 546.45 | 6.51 | 6.51 |
| 306.43 | 2.21 | 2.21 |
| 392.48 | 2.93 | 2.93 |
| 464.19 | 4.26 | 4.26 |
| 473.49 | 3.13 | 3.13 |
| 423.50 | 5.04 | 5.04 |
| 437.35 | 4.52 | 4.52 |
| 368.39 | 4.16 | 4.16 |
| 333.42 | 4.32 | 4.32 |
| 570.35 | 7.38 | 7.38 |
| 345.49 | 3.98 | 3.98 |
| 593.38 | 5.51 | 5.51 |
| 387.39 | 2.43 | 2.43 |
| 419.52 | 3.79 | 3.79 |
| 358.24 | 3.22 | 3.22 |
| 433.58 | 5.46 | 5.46 |
| 316.31 | 0.62 | 0.62 |
| 360.81 | 4.68 | 4.68 |
| 389.20 | 4.56 | 4.56 |
| 498.81 | 4.97 | 4.97 |
| 302.37 | 3.86 | 3.86 |
| 331.38 | 4.03 | 4.03 |
| 340.39 | 5.86 | 5.86 |
| 464.57 | 4.86 | 4.86 |
| 432.34 | 2.45 | 2.45 |
| 321.25 | 5.21 | 5.21 |
| 394.50 | 4.48 | 4.48 |
| 387.45 | 5.79 | 5.79 |
| 444.53 | 5.17 | 5.17 |
| 311.18 | 3.88 | 3.88 |
| 318.40 | 4.42 | 4.42 |
| 394.48 | 3.90 | 3.90 |
| 323.35 | 3.30 | 3.30 |
| 243.26 | 1.13 | 1.13 |
| 332.66 | 3.82 | 3.82 |
| 388.45 | 4.93 | 4.93 |
| 476.58 | 4.79 | 4.79 |
| 488.45 | 2.76 | 2.76 |
| 455.94 | 5.63 | 5.63 |
| 382.89 | 2.95 | 2.95 |
| 270.25 | -0.56 | -0.56 |
| 271.36 | 3.35 | 3.35 |
| 309.39 | 3.13 | 3.13 |
| 336.46 | 4.90 | 4.90 |
| 352.48 | 3.74 | 3.74 |
| 352.38 | 4.45 | 4.45 |
| 406.57 | 4.89 | 4.89 |
| 459.73 | 5.34 | 5.34 |
| 375.52 | 4.43 | 4.43 |
| 476.51 | 4.94 | 4.94 |
| 381.48 | 3.71 | 3.71 |
| 347.46 | 3.70 | 3.70 |
| 487.65 | 3.81 | 3.81 |
| 459.98 | 3.78 | 3.78 |
| 545.27 | 4.26 | 4.26 |
| 466.58 | 4.95 | 4.95 |
| 321.42 | 4.04 | 4.04 |
| 336.44 | 3.73 | 3.73 |
| 367.90 | 6.13 | 6.13 |
| 444.92 | 5.97 | 5.97 |
| 466.63 | 5.43 | 5.43 |
| 505.87 | 5.49 | 5.49 |
| 393.60 | 4.96 | 4.96 |
| 493.54 | 4.43 | 4.43 |
| 339.46 | 4.10 | 4.10 |
| 276.79 | 3.83 | 3.83 |
| 269.32 | 3.41 | 3.41 |
| 496.54 | 3.17 | 3.17 |
| 292.34 | 2.34 | 2.34 |
| 418.45 | 2.91 | 2.91 |
| 313.40 | 5.17 | 5.17 |
| 355.80 | 5.01 | 5.01 |
| 450.95 | 4.65 | 4.65 |
| 363.46 | 4.91 | 4.91 |
| 379.03 | 5.46 | 5.46 |
| 470.55 | 4.29 | 4.29 |
| 481.30 | 4.11 | 4.11 |
| 472.55 | 2.00 | 2.00 |
| 385.39 | 4.58 | 4.58 |
| 353.35 | 2.71 | 2.71 |
| 278.32 | 3.45 | 3.45 |
| 459.53 | 6.38 | 6.38 |
| 318.38 | 3.85 | 3.85 |
| 484.60 | 5.43 | 5.43 |
| 445.44 | 3.06 | 3.06 |
| 324.38 | 3.92 | 3.92 |
| 335.43 | 5.21 | 5.21 |
| 495.56 | 4.79 | 4.79 |
| 264.32 | 3.76 | 3.76 |
| 341.80 | 4.63 | 4.63 |
| 457.91 | 5.27 | 5.27 |
| 388.49 | 5.49 | 5.49 |
| 515.35 | 0.44 | 0.44 |
| 430.53 | 5.20 | 5.20 |
| 487.67 | 3.28 | 3.28 |
| 374.32 | 5.22 | 5.22 |
| 481.57 | 3.53 | 3.53 |
| 311.36 | 3.59 | 3.59 |
| 452.54 | 4.41 | 4.41 |
| 518.55 | 7.38 | 7.38 |
| 595.46 | 4.07 | 4.07 |
| 404.43 | 2.52 | 2.52 |
| 444.56 | 5.49 | 5.49 |
| 352.46 | 3.98 | 3.98 |
| 339.89 | 3.94 | 3.94 |
| 322.33 | 3.18 | 3.18 |
| 467.39 | 5.19 | 5.19 |
| 286.36 | 3.14 | 3.14 |
| 451.57 | 3.46 | 3.46 |
| 335.64 | 4.74 | 4.74 |
| 331.18 | 3.09 | 3.09 |
| 459.51 | 2.41 | 2.41 |
| 288.73 | 3.81 | 3.81 |
| 454.70 | 7.75 | 7.75 |
| 326.80 | 4.56 | 4.56 |
| 357.46 | 4.27 | 4.27 |
| 383.49 | 3.89 | 3.89 |
| 327.38 | 4.56 | 4.56 |
| 357.27 | 3.54 | 3.54 |
| 337.42 | 3.90 | 3.90 |
| 252.25 | 1.05 | 1.05 |
| 316.36 | 3.90 | 3.90 |
| 430.53 | 4.30 | 4.30 |
| 489.58 | 4.89 | 4.89 |
| 408.52 | 3.44 | 3.44 |
| 323.40 | 1.87 | 1.87 |
| 416.43 | 3.66 | 3.66 |
| 444.51 | 5.78 | 5.78 |
| 306.70 | 3.56 | 3.56 |
| 396.19 | 3.70 | 3.70 |
| 341.16 | 4.35 | 4.35 |
| 364.40 | 4.17 | 4.17 |
| 504.91 | 3.96 | 3.96 |
| 323.44 | 4.38 | 4.38 |
| 401.54 | 5.35 | 5.35 |
| 292.35 | 3.54 | 3.54 |
| 415.49 | 4.74 | 4.74 |
| 372.47 | 4.98 | 4.98 |
| 335.43 | 4.85 | 4.85 |
| 366.72 | 5.35 | 5.35 |
| 586.11 | 5.54 | 5.54 |
| 340.36 | 4.82 | 4.82 |
| 459.73 | 5.34 | 5.34 |
| 461.43 | 3.51 | 3.51 |
| 505.00 | 5.23 | 5.23 |
| 354.35 | 4.54 | 4.54 |
| 513.54 | 4.16 | 4.16 |
| 546.87 | 6.30 | 6.30 |
| 311.43 | 4.14 | 4.14 |
| 471.51 | 4.90 | 4.90 |
| 327.21 | 3.03 | 3.03 |
| 265.34 | 3.77 | 3.77 |
| 379.32 | 3.40 | 3.40 |
| 354.45 | 6.74 | 6.74 |
| 268.07 | 1.71 | 1.71 |
| 803.86 | 4.01 | 4.01 |
| 306.20 | 3.19 | 3.19 |
| 458.04 | 5.09 | 5.09 |
| 255.23 | 1.12 | 1.12 |
| 396.06 | 3.87 | 3.87 |
| 385.44 | 3.13 | 3.13 |
| 354.50 | 4.30 | 4.30 |
| 408.52 | 4.62 | 4.62 |
| 533.04 | 5.11 | 5.11 |
| 295.77 | 4.64 | 4.64 |
| 324.61 | 4.87 | 4.87 |
| 430.42 | 3.78 | 3.78 |
| 458.54 | 4.07 | 4.07 |
| 422.85 | 4.07 | 4.07 |
| 380.41 | 4.32 | 4.32 |
| 541.63 | 5.88 | 5.88 |
| 372.38 | 3.35 | 3.35 |
| 522.63 | 4.74 | 4.74 |
| 371.74 | 2.66 | 2.66 |
| 432.46 | 3.76 | 3.76 |
| 446.48 | 4.06 | 4.06 |
| 472.64 | 5.02 | 5.02 |
| 324.16 | 4.22 | 4.22 |
| 457.49 | 3.94 | 3.94 |
| 279.34 | 3.89 | 3.89 |
| 372.76 | 2.92 | 2.92 |
| 401.51 | 3.89 | 3.89 |
| 427.34 | 4.01 | 4.01 |
| 392.84 | 5.38 | 5.38 |
| 349.45 | 3.80 | 3.80 |
| 414.46 | 3.09 | 3.09 |
| 350.37 | 4.54 | 4.54 |
| 410.59 | 5.32 | 5.32 |
| 454.15 | 4.35 | 4.35 |
| 365.43 | 4.11 | 4.11 |
| 399.04 | 4.40 | 4.40 |
| 413.07 | 4.67 | 4.67 |
| 519.97 | 4.85 | 4.85 |
| 356.40 | 5.19 | 5.19 |
| 287.43 | 4.84 | 4.84 |
| 283.35 | 3.74 | 3.74 |
| 288.39 | 5.28 | 5.28 |
| 479.49 | 2.59 | 2.59 |
| 499.55 | 4.51 | 4.51 |
| 432.55 | 5.48 | 5.48 |