PUBCHEM_BIOASSAY: Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B. (Class of assay: confirmatory) [...

Basic Information

ID: ALA1738670

Type: Functional

Description: PUBCHEM_BIOASSAY: Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504462, AID504475]

Format: BAO_0000019

Organism: Homo sapiens

Target: Cysteine protease ATG4B(ALA1741221)

Document: ALA1201862

PubChem Source: AID:504756

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA1738670

IC50

Total(318)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
278.44	5.66	5.66
310.40	5.19	5.19
309.15	4.88	4.88
208.22	2.73	2.73
223.23	2.31	2.31
384.45	6.46	6.46
261.71	4.09	4.09
294.15	2.99	2.99
416.55	3.73	3.73
310.40	1.73	1.73
372.38	4.25	4.25
287.17	4.56	4.56
324.41	4.54	4.54
506.48	6.09	6.09
360.64	5.10	5.10
324.81	4.79	4.79
207.19	-1.32	-1.32
309.33	1.03	1.03
374.51	4.02	4.02
290.75	1.76	1.76
329.36	4.73	4.73
544.99	-0.35	-0.35
381.48	4.74	4.74
364.40	3.95	3.95
428.87	4.00	4.00
425.52	5.48	5.48
330.69	2.67	2.67
466.73	4.56	4.56
313.38	3.95	3.95
430.46	3.97	3.97
457.49	3.43	3.43
377.50	3.02	3.02
433.58	5.38	5.38
246.33	3.92	3.92
524.40	4.64	4.64
476.55	5.02	5.02
406.94	3.37	3.37
292.71	2.23	2.23
475.57	5.94	5.94
350.46	4.11	4.11
456.96	4.85	4.85
351.83	4.70	4.70
321.38	2.70	2.70
399.26	4.25	4.25
235.25	-0.67	-0.67
331.78	4.46	4.46
363.37	3.44	3.44
457.33	3.66	3.66
462.51	4.81	4.81
390.49	3.42	3.42
321.25	4.32	4.32
371.85	3.89	3.89
300.36	4.48	4.48
323.13	4.49	4.49
477.01	5.27	5.27
434.52	5.67	5.67
417.63	4.03	4.03
348.79	4.88	4.88
274.36	3.40	3.40
366.44	5.24	5.24
253.68	4.23	4.23
499.79	5.34	5.34
427.51	2.66	2.66
385.92	4.64	4.64
412.47	5.05	5.05
350.87	4.84	4.84
306.46	3.89	3.89
546.57	5.70	5.70
376.48	5.60	5.60
260.36	4.40	4.40
403.46	4.57	4.57
387.88	5.42	5.42
475.55	4.29	4.29
284.14	3.53	3.53
388.83	5.26	5.26
351.49	4.53	4.53
424.83	5.81	5.81
470.53	3.06	3.06
369.83	5.34	5.34
488.46	4.66	4.66
476.55	5.02	5.02
371.36	5.21	5.21
364.86	5.45	5.45
485.06	4.83	4.83
457.27	5.04	5.04
326.34	4.48	4.48
405.54	4.26	4.26
385.51	3.72	3.72
368.44	4.52	4.52
365.40	4.34	4.34
314.80	4.77	4.77
336.44	4.67	4.67
325.87	3.55	3.55
417.45	3.75	3.75
451.94	4.25	4.25
292.32	1.48	1.48
370.41	4.59	4.59
348.15	4.94	4.94
318.13	3.96	3.96
346.27	2.07	2.07
463.56	4.94	4.94
361.24	3.16	3.16
329.49	5.03	5.03
452.15	4.67	4.67
388.28	6.16	6.16
357.42	2.78	2.78
437.30	3.30	3.30
404.44	4.44	4.44
236.27	3.68	3.68
389.46	4.25	4.25
352.84	3.43	3.43
317.39	4.68	4.68
351.19	2.98	2.98
368.86	4.55	4.55
354.50	4.37	4.37
473.91	5.69	5.69
546.45	6.51	6.51
306.43	2.21	2.21
392.48	2.93	2.93
464.19	4.26	4.26
473.49	3.13	3.13
423.50	5.04	5.04
437.35	4.52	4.52
368.39	4.16	4.16
333.42	4.32	4.32
570.35	7.38	7.38
345.49	3.98	3.98
593.38	5.51	5.51
387.39	2.43	2.43
419.52	3.79	3.79
358.24	3.22	3.22
433.58	5.46	5.46
316.31	0.62	0.62
360.81	4.68	4.68
389.20	4.56	4.56
498.81	4.97	4.97
302.37	3.86	3.86
331.38	4.03	4.03
340.39	5.86	5.86
464.57	4.86	4.86
432.34	2.45	2.45
321.25	5.21	5.21
394.50	4.48	4.48
387.45	5.79	5.79
444.53	5.17	5.17
311.18	3.88	3.88
318.40	4.42	4.42
394.48	3.90	3.90
323.35	3.30	3.30
243.26	1.13	1.13
332.66	3.82	3.82
388.45	4.93	4.93
476.58	4.79	4.79
488.45	2.76	2.76
455.94	5.63	5.63
382.89	2.95	2.95
270.25	-0.56	-0.56
271.36	3.35	3.35
309.39	3.13	3.13
336.46	4.90	4.90
352.48	3.74	3.74
352.38	4.45	4.45
406.57	4.89	4.89
459.73	5.34	5.34
375.52	4.43	4.43
476.51	4.94	4.94
381.48	3.71	3.71
347.46	3.70	3.70
487.65	3.81	3.81
459.98	3.78	3.78
545.27	4.26	4.26
466.58	4.95	4.95
321.42	4.04	4.04
336.44	3.73	3.73
367.90	6.13	6.13
444.92	5.97	5.97
466.63	5.43	5.43
505.87	5.49	5.49
393.60	4.96	4.96
493.54	4.43	4.43
339.46	4.10	4.10
276.79	3.83	3.83
269.32	3.41	3.41
496.54	3.17	3.17
292.34	2.34	2.34
418.45	2.91	2.91
313.40	5.17	5.17
355.80	5.01	5.01
450.95	4.65	4.65
363.46	4.91	4.91
379.03	5.46	5.46
470.55	4.29	4.29
481.30	4.11	4.11
472.55	2.00	2.00
385.39	4.58	4.58
353.35	2.71	2.71
278.32	3.45	3.45
459.53	6.38	6.38
318.38	3.85	3.85
484.60	5.43	5.43
445.44	3.06	3.06
324.38	3.92	3.92
335.43	5.21	5.21
495.56	4.79	4.79
264.32	3.76	3.76
341.80	4.63	4.63
457.91	5.27	5.27
388.49	5.49	5.49
515.35	0.44	0.44
430.53	5.20	5.20
487.67	3.28	3.28
374.32	5.22	5.22
481.57	3.53	3.53
311.36	3.59	3.59
452.54	4.41	4.41
518.55	7.38	7.38
595.46	4.07	4.07
404.43	2.52	2.52
444.56	5.49	5.49
352.46	3.98	3.98
339.89	3.94	3.94
322.33	3.18	3.18
467.39	5.19	5.19
286.36	3.14	3.14
451.57	3.46	3.46
335.64	4.74	4.74
331.18	3.09	3.09
459.51	2.41	2.41
288.73	3.81	3.81
454.70	7.75	7.75
326.80	4.56	4.56
357.46	4.27	4.27
383.49	3.89	3.89
327.38	4.56	4.56
357.27	3.54	3.54
337.42	3.90	3.90
252.25	1.05	1.05
316.36	3.90	3.90
430.53	4.30	4.30
489.58	4.89	4.89
408.52	3.44	3.44
323.40	1.87	1.87
416.43	3.66	3.66
444.51	5.78	5.78
306.70	3.56	3.56
396.19	3.70	3.70
341.16	4.35	4.35
364.40	4.17	4.17
504.91	3.96	3.96
323.44	4.38	4.38
401.54	5.35	5.35
292.35	3.54	3.54
415.49	4.74	4.74
372.47	4.98	4.98
335.43	4.85	4.85
366.72	5.35	5.35
586.11	5.54	5.54
340.36	4.82	4.82
459.73	5.34	5.34
461.43	3.51	3.51
505.00	5.23	5.23
354.35	4.54	4.54
513.54	4.16	4.16
546.87	6.30	6.30
311.43	4.14	4.14
471.51	4.90	4.90
327.21	3.03	3.03
265.34	3.77	3.77
379.32	3.40	3.40
354.45	6.74	6.74
268.07	1.71	1.71
803.86	4.01	4.01
306.20	3.19	3.19
458.04	5.09	5.09
255.23	1.12	1.12
396.06	3.87	3.87
385.44	3.13	3.13
354.50	4.30	4.30
408.52	4.62	4.62
533.04	5.11	5.11
295.77	4.64	4.64
324.61	4.87	4.87
430.42	3.78	3.78
458.54	4.07	4.07
422.85	4.07	4.07
380.41	4.32	4.32
541.63	5.88	5.88
372.38	3.35	3.35
522.63	4.74	4.74
371.74	2.66	2.66
432.46	3.76	3.76
446.48	4.06	4.06
472.64	5.02	5.02
324.16	4.22	4.22
457.49	3.94	3.94
279.34	3.89	3.89
372.76	2.92	2.92
401.51	3.89	3.89
427.34	4.01	4.01
392.84	5.38	5.38
349.45	3.80	3.80
414.46	3.09	3.09
350.37	4.54	4.54
410.59	5.32	5.32
454.15	4.35	4.35
365.43	4.11	4.11
399.04	4.40	4.40
413.07	4.67	4.67
519.97	4.85	4.85
356.40	5.19	5.19
287.43	4.84	4.84
283.35	3.74	3.74
288.39	5.28	5.28
479.49	2.59	2.59
499.55	4.51	4.51
432.55	5.48	5.48