Basic Information
ID: ALA1738673
Type: Functional
Description: PUBCHEM_BIOASSAY: HSF-1 induced GFP reporter and Doxycycline induced RFP reporter Measured in Cell-Based System Using Plate Reader - 2038-03_Inhibitor_DoseNoFile_CherryPick_Internal-Standard_Set3. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2118]
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA1738673
AC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 266.26 | -1.38 | -1.38 |
| 285.24 | -1.84 | -1.84 |
| 348.43 | 2.53 | 2.53 |
| 238.24 | 3.17 | 3.17 |
| 287.10 | 2.77 | 2.77 |
| 265.31 | 0.50 | 0.50 |
| 328.35 | 1.55 | 1.55 |
| 320.41 | 2.87 | 2.87 |
| 290.43 | 3.09 | 3.09 |
| 252.27 | 3.47 | 3.47 |
| 346.48 | 4.04 | 4.04 |
| 517.11 | 4.94 | 4.94 |
| 232.32 | 2.77 | 2.77 |
| 343.79 | 3.87 | 3.87 |
| 365.85 | 4.93 | 4.93 |
| 346.34 | 2.69 | 2.69 |
| 241.08 | 2.54 | 2.54 |
| 215.22 | 1.21 | 1.21 |
| 409.85 | 4.68 | 4.68 |
| 280.17 | 3.24 | 3.24 |
| 343.18 | 3.69 | 3.69 |
| 478.62 | 4.22 | 4.22 |
| 340.45 | 5.33 | 5.33 |
| 507.57 | 4.31 | 4.31 |
| 255.35 | 3.86 | 3.86 |
| 437.53 | 1.98 | 1.98 |
| 392.24 | 3.82 | 3.82 |
| 422.46 | 2.52 | 2.52 |
| 245.71 | 3.53 | 3.53 |
| 262.33 | 2.94 | 2.94 |
| 313.31 | 0.80 | 0.80 |
| 281.31 | 0.98 | 0.98 |
| 340.41 | 3.42 | 3.42 |
| 375.45 | 2.00 | 2.00 |
| 287.32 | 2.91 | 2.91 |
| 329.38 | 2.82 | 2.82 |
| 356.82 | 3.12 | 3.12 |
| 351.41 | 3.93 | 3.93 |
| 424.51 | 2.77 | 2.77 |
| 469.61 | 3.92 | 3.92 |
| 356.49 | 3.63 | 3.63 |
| 445.36 | 3.12 | 3.12 |
| 423.52 | 4.07 | 4.07 |
| 373.55 | 4.45 | 4.45 |
| 302.40 | 3.31 | 3.31 |
| 368.39 | 3.89 | 3.89 |
| 393.42 | 1.76 | 1.76 |
| 463.54 | 1.98 | 1.98 |
| 464.53 | 6.21 | 6.21 |
| 528.65 | 4.17 | 4.17 |
| 557.69 | 3.47 | 3.47 |
| 259.27 | 1.02 | 1.02 |
| 285.34 | 3.51 | 3.51 |
| 340.69 | 3.97 | 3.97 |
| 417.92 | 3.53 | 3.53 |
| 300.75 | 2.40 | 2.40 |
| 200.28 | 2.46 | 2.46 |
| 271.34 | 4.00 | 4.00 |
| 354.45 | 2.85 | 2.85 |
| 428.47 | 3.69 | 3.69 |
| 382.51 | 2.60 | 2.60 |
| 267.24 | 3.33 | 3.33 |
| 369.27 | 4.19 | 4.19 |
| 487.00 | 2.60 | 2.60 |
| 475.57 | 2.15 | 2.15 |
| 278.29 | 2.13 | 2.13 |
| 273.38 | 3.42 | 3.42 |
| 225.25 | 2.43 | 2.43 |
| 266.34 | 4.37 | 4.37 |
| 467.39 | 2.58 | 2.58 |
| 363.26 | 3.52 | 3.52 |
| 563.62 | 6.14 | 6.14 |
| 319.41 | 4.59 | 4.59 |
| 371.41 | 4.43 | 4.43 |
| 426.54 | 2.35 | 2.35 |
| 357.31 | 1.65 | 1.65 |
| 149.22 | 2.20 | 2.20 |
| 322.46 | 4.47 | 4.47 |
| 445.56 | 5.35 | 5.35 |
| 482.36 | 4.37 | 4.37 |
| 345.21 | 3.53 | 3.53 |
| 489.62 | 3.24 | 3.24 |
| 349.44 | 3.82 | 3.82 |
| 355.42 | 3.04 | 3.04 |
| 349.88 | 4.08 | 4.08 |
| 253.37 | 5.09 | 5.09 |
| 342.40 | 1.97 | 1.97 |
| 502.42 | 5.28 | 5.28 |
| 464.50 | 5.43 | 5.43 |
| 379.41 | 3.70 | 3.70 |
| 425.58 | 3.94 | 3.94 |
| 560.73 | 3.29 | 3.29 |
| 330.34 | 2.58 | 2.58 |
| 360.44 | 2.66 | 2.66 |
| 351.82 | 3.27 | 3.27 |
| 479.56 | 2.89 | 2.89 |
| 251.24 | 1.88 | 1.88 |
| 473.96 | 2.50 | 2.50 |
| 297.75 | 3.14 | 3.14 |
| 353.42 | 3.39 | 3.39 |
| 403.51 | 4.08 | 4.08 |
| 287.43 | 4.46 | 4.46 |
| 377.33 | 3.02 | 3.02 |
| 380.52 | 4.32 | 4.32 |
| 453.52 | 2.95 | 2.95 |
| 204.19 | 1.69 | 1.69 |
| 337.40 | 3.80 | 3.80 |
| 402.28 | 5.66 | 5.66 |
| 234.21 | 2.61 | 2.61 |
| 243.27 | 2.74 | 2.74 |
| 293.37 | 4.13 | 4.13 |
| 475.35 | 3.47 | 3.47 |
| 431.88 | 5.78 | 5.78 |
| 431.42 | 3.15 | 3.15 |
| 451.53 | 1.22 | 1.22 |
| 345.44 | 3.57 | 3.57 |
| 397.86 | 2.91 | 2.91 |
| 353.49 | 4.76 | 4.76 |
| 269.31 | 2.47 | 2.47 |
| 498.98 | 3.93 | 3.93 |
| 425.96 | 4.82 | 4.82 |
| 297.35 | 2.82 | 2.82 |
| 358.49 | 3.87 | 3.87 |
| 417.51 | 5.17 | 5.17 |
| 407.56 | 3.83 | 3.83 |
| 218.22 | 1.67 | 1.67 |
| 398.30 | 3.25 | 3.25 |
| 283.28 | 2.55 | 2.55 |
| 400.31 | 4.31 | 4.31 |
| 308.41 | 4.22 | 4.22 |
| 351.41 | 3.54 | 3.54 |
| 311.17 | 3.00 | 3.00 |
| 473.64 | 3.03 | 3.03 |
| 230.27 | 2.19 | 2.19 |
| 251.76 | 3.59 | 3.59 |
| 299.39 | 1.80 | 1.80 |
| 262.70 | 3.08 | 3.08 |
| 424.52 | 4.01 | 4.01 |
| 426.54 | 2.33 | 2.33 |
| 293.32 | 2.92 | 2.92 |
| 303.67 | 4.51 | 4.51 |
| 366.38 | 2.95 | 2.95 |
| 404.47 | 4.06 | 4.06 |
| 444.58 | 3.58 | 3.58 |
| 430.51 | 4.81 | 4.81 |
| 381.50 | 3.39 | 3.39 |
| 391.46 | 3.43 | 3.43 |
| 358.42 | 3.53 | 3.53 |
| 352.43 | 3.64 | 3.64 |
| 417.51 | 4.74 | 4.74 |
| 381.43 | 1.85 | 1.85 |
| 442.71 | 4.32 | 4.32 |
| 418.49 | 2.06 | 2.06 |
| 417.49 | 2.09 | 2.09 |
| 350.51 | 3.94 | 3.94 |
| 346.43 | 3.62 | 3.62 |
| 278.33 | 3.29 | 3.29 |
| 264.33 | 2.72 | 2.72 |
| 429.50 | 3.44 | 3.44 |
| 329.83 | 2.50 | 2.50 |
| 472.88 | 5.09 | 5.09 |
| 447.61 | 4.69 | 4.69 |
| 417.87 | 3.36 | 3.36 |
| 399.45 | 3.43 | 3.43 |
| 240.27 | 1.99 | 1.99 |
| 373.28 | 3.85 | 3.85 |
| 389.50 | 3.69 | 3.69 |
| 324.34 | 3.23 | 3.23 |
| 311.39 | 2.95 | 2.95 |
| 330.73 | 3.56 | 3.56 |
| 457.46 | -0.17 | -0.17 |
| 453.45 | 5.06 | 5.06 |
| 413.57 | 3.90 | 3.90 |
| 283.37 | 4.43 | 4.43 |
| 322.75 | 1.49 | 1.49 |
| 368.40 | 0.29 | 0.29 |
| 379.42 | 4.21 | 4.21 |
| 425.92 | 4.79 | 4.79 |
| 369.40 | 0.48 | 0.48 |
| 422.52 | 5.83 | 5.83 |
| 363.24 | 4.71 | 4.71 |
| 387.39 | 1.72 | 1.72 |
| 468.53 | 3.76 | 3.76 |
| 384.46 | 2.74 | 2.74 |
| 445.38 | 4.73 | 4.73 |
| 239.30 | 3.21 | 3.21 |
| 313.36 | 3.96 | 3.96 |
| 481.62 | 4.64 | 4.64 |
| 438.90 | 5.25 | 5.25 |
| 475.30 | 5.60 | 5.60 |
| 250.26 | 1.46 | 1.46 |
| 290.37 | 3.89 | 3.89 |
| 384.46 | 4.34 | 4.34 |
| 328.39 | 3.35 | 3.35 |
| 376.32 | 3.24 | 3.24 |
| 480.98 | 5.21 | 5.21 |
| 298.30 | 1.89 | 1.89 |
| 392.39 | 2.10 | 2.10 |
| 268.32 | 2.63 | 2.63 |
| 510.64 | 4.73 | 4.73 |
| 357.41 | 3.75 | 3.75 |
| 301.39 | 5.36 | 5.36 |
| 354.83 | 2.34 | 2.34 |
| 400.91 | 3.01 | 3.01 |
| 397.53 | 4.01 | 4.01 |
| 362.82 | 4.08 | 4.08 |
| 445.53 | 3.12 | 3.12 |
| 310.27 | 3.44 | 3.44 |
| 427.51 | 3.62 | 3.62 |
| 409.83 | 2.45 | 2.45 |
| 327.38 | 3.75 | 3.75 |
| 324.43 | 3.35 | 3.35 |
| 294.24 | 2.82 | 2.82 |
| 395.46 | 3.49 | 3.49 |
| 391.47 | 3.98 | 3.98 |
| 394.47 | 4.68 | 4.68 |
| 402.55 | 3.42 | 3.42 |
| 265.24 | 3.32 | 3.32 |
| 473.56 | 1.06 | 1.06 |
| 300.32 | 2.80 | 2.80 |
| 431.47 | 2.03 | 2.03 |
| 396.85 | 3.23 | 3.23 |
| 419.57 | 4.21 | 4.21 |
| 484.53 | 3.09 | 3.09 |
| 331.41 | 3.96 | 3.96 |
| 341.37 | 3.89 | 3.89 |
| 222.25 | 2.49 | 2.49 |
| 390.45 | 3.52 | 3.52 |
| 332.37 | 2.43 | 2.43 |
| 258.51 | 2.63 | 2.63 |
| 330.47 | 4.26 | 4.26 |
| 432.57 | 3.38 | 3.38 |
| 300.37 | 3.95 | 3.95 |
| 604.63 | 4.37 | 4.37 |
| 361.46 | 3.91 | 3.91 |
| 297.38 | 0.90 | 0.90 |
| 444.51 | 0.83 | 0.83 |
| 434.01 | 5.09 | 5.09 |
| 473.57 | 0.79 | 0.79 |
| 314.82 | 4.61 | 4.61 |
| 476.64 | 3.31 | 3.31 |
| 308.36 | 1.32 | 1.32 |
| 467.99 | 5.50 | 5.50 |
| 324.85 | 3.14 | 3.14 |
| 423.49 | 4.32 | 4.32 |
| 279.34 | 3.59 | 3.59 |
| 437.82 | 3.06 | 3.06 |
| 353.45 | 3.32 | 3.32 |
| 331.84 | 5.23 | 5.23 |
| 307.42 | 3.49 | 3.49 |
| 298.77 | 1.84 | 1.84 |
| 452.53 | 1.85 | 1.85 |
| 302.28 | 2.57 | 2.57 |
| 396.52 | 3.26 | 3.26 |
| 350.42 | 3.91 | 3.91 |
| 308.23 | 2.38 | 2.38 |
| 487.50 | 4.96 | 4.96 |
| 218.26 | 2.13 | 2.13 |
| 403.53 | 4.97 | 4.97 |
| 370.22 | 2.77 | 2.77 |
| 359.41 | 4.58 | 4.58 |
| 359.52 | 4.22 | 4.22 |
| 382.42 | 1.25 | 1.25 |
| 512.64 | 4.71 | 4.71 |
| 398.47 | 4.55 | 4.55 |
| 343.48 | 3.97 | 3.97 |
| 289.77 | 2.59 | 2.59 |
| 477.55 | 2.26 | 2.26 |
| 284.31 | 4.40 | 4.40 |
| 373.84 | 1.50 | 1.50 |
| 238.63 | 2.10 | 2.10 |
| 329.76 | 3.86 | 3.86 |
| 511.50 | 4.18 | 4.18 |
| 398.46 | 2.25 | 2.25 |
| 365.39 | 3.97 | 3.97 |
| 473.49 | 3.04 | 3.04 |
| 269.34 | 3.69 | 3.69 |
| 294.35 | 3.73 | 3.73 |
| 386.48 | 2.45 | 2.45 |
| 363.40 | 3.82 | 3.82 |
| 437.52 | 3.48 | 3.48 |
| 334.40 | 1.95 | 1.95 |
| 345.36 | 3.21 | 3.21 |
| 321.45 | 2.99 | 2.99 |
| 300.36 | 3.11 | 3.11 |
| 283.33 | 3.33 | 3.33 |
| 301.78 | 3.59 | 3.59 |
| 439.32 | 3.54 | 3.54 |
| 386.40 | 4.57 | 4.57 |
| 352.24 | 2.52 | 2.52 |
| 323.74 | 3.50 | 3.50 |
| 356.38 | 2.88 | 2.88 |
| 433.49 | 1.85 | 1.85 |
| 264.26 | 1.82 | 1.82 |
| 407.56 | 4.28 | 4.28 |
| 364.50 | 2.44 | 2.44 |
| 481.09 | 3.12 | 3.12 |
| 367.37 | 3.26 | 3.26 |
| 549.74 | 4.42 | 4.42 |
| 322.36 | 3.81 | 3.81 |
| 418.48 | 1.30 | 1.30 |
| 274.28 | 2.99 | 2.99 |
| 266.33 | 1.01 | 1.01 |
| 314.77 | 4.42 | 4.42 |
| 381.46 | 3.73 | 3.73 |
| 418.49 | 3.83 | 3.83 |
| 350.42 | 3.81 | 3.81 |
| 351.40 | 4.47 | 4.47 |
| 427.29 | 2.01 | 2.01 |
| 196.21 | 2.51 | 2.51 |
| 205.21 | 2.18 | 2.18 |
| 413.36 | 0.88 | 0.88 |
| 283.25 | 3.90 | 3.90 |
| 416.32 | 4.53 | 4.53 |
| 422.44 | 5.25 | 5.25 |
| 271.28 | 1.91 | 1.91 |
| 277.39 | 2.58 | 2.58 |
| 406.49 | 4.53 | 4.53 |
| 329.38 | 2.00 | 2.00 |
| 273.72 | 3.37 | 3.37 |
| 373.37 | 1.38 | 1.38 |
| 498.56 | 2.93 | 2.93 |
| 348.86 | 3.41 | 3.41 |
| 344.01 | 3.07 | 3.07 |
| 495.63 | 4.81 | 4.81 |
| 430.36 | 3.59 | 3.59 |
| 334.72 | 0.49 | 0.49 |
| 357.58 | 3.30 | 3.30 |
| 319.36 | 2.53 | 2.53 |
| 312.40 | 3.33 | 3.33 |
| 361.47 | 5.22 | 5.22 |
| 222.29 | 3.64 | 3.64 |
| 340.49 | 4.65 | 4.65 |
| 455.63 | 5.35 | 5.35 |
| 378.48 | 3.32 | 3.32 |
| 320.39 | 4.12 | 4.12 |
| 428.33 | 4.03 | 4.03 |
| 303.40 | 2.98 | 2.98 |
| 374.42 | 4.06 | 4.06 |
| 440.93 | 2.36 | 2.36 |
| 316.18 | 3.13 | 3.13 |
| 381.43 | 3.44 | 3.44 |
| 294.36 | 3.39 | 3.39 |
| 362.48 | 2.61 | 2.61 |
| 258.32 | 3.52 | 3.52 |
| 455.39 | 3.35 | 3.35 |
| 383.35 | 4.24 | 4.24 |
| 394.50 | 3.84 | 3.84 |
| 381.43 | 4.95 | 4.95 |
| 283.39 | 2.60 | 2.60 |
| 297.31 | 2.84 | 2.84 |
| 382.38 | 3.79 | 3.79 |
| 327.72 | 3.33 | 3.33 |
| 309.37 | 4.39 | 4.39 |
| 280.40 | 4.44 | 4.44 |
| 354.77 | 4.83 | 4.83 |
| 318.42 | 2.49 | 2.49 |
| 358.40 | 3.92 | 3.92 |
| 462.53 | 1.64 | 1.64 |
| 272.38 | 3.35 | 3.35 |
| 408.85 | 3.75 | 3.75 |
| 281.79 | 2.95 | 2.95 |
| 445.88 | 2.76 | 2.76 |
| 269.35 | 2.64 | 2.64 |
| 422.47 | 2.93 | 2.93 |
| 288.39 | 3.88 | 3.88 |
| 415.30 | 3.27 | 3.27 |
| 497.65 | 3.90 | 3.90 |
| 274.32 | 2.24 | 2.24 |
| 486.49 | 1.01 | 1.01 |
| 524.04 | 5.86 | 5.86 |
| 402.43 | 3.96 | 3.96 |
| 463.60 | 5.03 | 5.03 |
| 453.50 | 3.87 | 3.87 |
| 323.38 | 2.05 | 2.05 |
| 434.52 | 2.37 | 2.37 |
| 382.49 | 1.74 | 1.74 |
| 436.56 | 3.54 | 3.54 |
| 407.33 | 4.02 | 4.02 |
| 384.36 | 2.93 | 2.93 |
| 369.90 | 3.24 | 3.24 |
| 368.35 | 2.76 | 2.76 |
| 306.37 | 3.79 | 3.79 |
| 412.51 | 3.53 | 3.53 |
| 360.21 | 4.15 | 4.15 |
| 459.55 | 3.68 | 3.68 |
| 375.52 | 3.62 | 3.62 |
| 292.34 | 1.48 | 1.48 |
| 437.54 | 2.87 | 2.87 |
| 320.75 | 1.22 | 1.22 |
| 418.49 | 4.87 | 4.87 |
| 383.28 | 5.14 | 5.14 |
| 400.50 | 5.36 | 5.36 |
| 432.50 | 4.32 | 4.32 |
| 315.35 | 2.63 | 2.63 |
| 394.48 | 4.12 | 4.12 |
| 308.34 | 3.01 | 3.01 |
| 501.54 | 4.71 | 4.71 |
| 370.41 | 3.91 | 3.91 |
| 531.48 | 5.41 | 5.41 |
| 438.55 | 3.00 | 3.00 |
| 272.31 | 3.25 | 3.25 |
| 518.59 | 1.34 | 1.34 |
| 422.53 | 4.74 | 4.74 |
| 270.38 | 4.18 | 4.18 |
| 305.34 | 3.45 | 3.45 |
| 327.38 | 2.60 | 2.60 |
| 387.94 | 5.10 | 5.10 |
| 318.38 | 3.24 | 3.24 |
| 309.33 | 2.63 | 2.63 |
| 343.43 | 3.77 | 3.77 |
| 474.54 | 4.68 | 4.68 |
| 350.38 | 3.32 | 3.32 |
| 315.42 | 3.40 | 3.40 |
| 401.49 | 0.85 | 0.85 |
| 314.36 | 3.31 | 3.31 |