Basic Information
ID: ALA1738675
Type: Functional
Description: PUBCHEM_BIOASSAY: Validation screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493125, AID504467]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1738675
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 317.18 | 4.50 | 4.50 |
| 383.41 | 1.78 | 1.78 |
| 160.22 | 1.67 | 1.67 |
| 264.37 | 3.08 | 3.08 |
| 391.56 | 6.86 | 6.86 |
| 167.30 | 2.42 | 2.42 |
| 314.86 | 4.53 | 4.53 |
| 290.32 | 1.26 | 1.26 |
| 407.51 | 4.95 | 4.95 |
| 341.43 | 0.56 | 0.56 |
| 270.24 | 2.58 | 2.58 |
| 328.41 | 2.14 | 2.14 |
| 169.18 | 0.09 | 0.09 |
| 297.75 | -0.35 | -0.35 |
| 326.83 | 3.72 | 3.72 |
| 263.38 | 3.83 | 3.83 |
| 399.97 | 5.97 | 5.97 |
| 393.47 | 4.51 | 4.51 |
| 270.24 | 2.58 | 2.58 |
| 329.36 | 4.06 | 4.06 |
| 394.42 | 3.70 | 3.70 |
| 315.76 | 4.04 | 4.04 |
| 232.28 | 1.86 | 1.86 |
| 196.20 | 0.64 | 0.64 |
| 214.22 | 0.73 | 0.73 |
| 254.24 | 2.87 | 2.87 |
| 302.24 | 1.99 | 1.99 |
| 267.33 | 2.85 | 2.85 |
| 375.87 | 4.43 | 4.43 |
| 361.53 | 4.84 | 4.84 |
| 272.18 | 3.33 | 3.33 |
| 444.49 | -0.14 | -0.14 |
| 395.48 | 3.22 | 3.22 |
| 348.36 | 2.08 | 2.08 |
| 369.37 | 3.52 | 3.52 |
| 318.87 | 4.89 | 4.89 |
| 1202.63 | ||
| 376.50 | 4.72 | 4.72 |
| 329.37 | 3.33 | 3.33 |
| 396.45 | 4.55 | 4.55 |
| 351.41 | 1.56 | 1.56 |
| 204.23 | 0.83 | 0.83 |
| 473.59 | 6.08 | 6.08 |
| 654.61 | 3.19 | 3.19 |
| 853.92 | 3.74 | 3.74 |
| 160.18 | 0.92 | 0.92 |
| 198.27 | 2.70 | 2.70 |
| 182.23 | 3.02 | 3.02 |
| 285.39 | 2.66 | 2.66 |
| 477.58 | 5.48 | 5.48 |
| 332.34 | 3.43 | 3.43 |
| 240.27 | 1.49 | 1.49 |
| 422.35 | 2.45 | 2.45 |
| 314.47 | 4.72 | 4.72 |
| 110.11 | 1.10 | 1.10 |
| 300.44 | 5.60 | 5.60 |
| 394.86 | 5.13 | 5.13 |
| 270.33 | 3.01 | 3.01 |
| 409.42 | 4.79 | 4.79 |
| 144.21 | 2.29 | 2.29 |
| 242.27 | 2.75 | 2.75 |
| 325.54 | 5.13 | 5.13 |
| 284.43 | 4.24 | 4.24 |
| 497.60 | 5.03 | 5.03 |
| 352.43 | 5.26 | 5.26 |
| 253.27 | 0.83 | 0.83 |
| 285.69 | 2.77 | 2.77 |
| 331.35 | 4.65 | 4.65 |
| 360.35 | 4.85 | 4.85 |
| 471.69 | 6.45 | 6.45 |
| 155.16 | -0.64 | -0.64 |
| 281.36 | 2.84 | 2.84 |
| 371.40 | 0.36 | 0.36 |
| 393.46 | 3.28 | 3.28 |
| 283.33 | 2.56 | 2.56 |
| 403.53 | 4.06 | 4.06 |
| 170.24 | 0.58 | 0.58 |
| 246.31 | 4.49 | 4.49 |
| 123.11 | -0.42 | -0.42 |
| 145.25 | -0.34 | -0.34 |
| 450.57 | 5.32 | 5.32 |
| 278.31 | 0.19 | 0.19 |
| 645.32 | 6.94 | 6.94 |
| 325.45 | 2.37 | 2.37 |
| 277.41 | 4.21 | 4.21 |
| 231.04 | 2.35 | 2.35 |
| 360.84 | 4.68 | 4.68 |
| 320.43 | 5.17 | 5.17 |
| 215.03 | 3.10 | 3.10 |
| 213.66 | 1.86 | 1.86 |
| 451.48 | 1.72 | 1.72 |
| 353.51 | 4.66 | 4.66 |
| 414.59 | 5.04 | 5.04 |
| 406.48 | 3.74 | 3.74 |
| 404.50 | 5.39 | 5.39 |
| 234.20 | 2.78 | 2.78 |
| 550.76 | 5.98 | 5.98 |
| 522.71 | 5.20 | 5.20 |
| 542.42 | 4.16 | 4.16 |
| 434.52 | 3.70 | 3.70 |
| 395.47 | 4.23 | 4.23 |
| 608.69 | 4.17 | 4.17 |
| 405.50 | 3.58 | 3.58 |
| 267.28 | 3.05 | 3.05 |
| 342.44 | 3.48 | 3.48 |
| 516.55 | 5.40 | 5.40 |
| 306.24 | 5.18 | 5.18 |
| 180.21 | 2.78 | 2.78 |
| 582.79 | 6.80 | 6.80 |
| 145.11 | -1.11 | -1.11 |
| 145.11 | -1.11 | -1.11 |
| 329.44 | 3.26 | 3.26 |
| 338.21 | 4.10 | 4.10 |
| 475.58 | 5.31 | 5.31 |
| 334.42 | 2.38 | 2.38 |
| 370.46 | 5.59 | 5.59 |
| 274.27 | 2.32 | 2.32 |
| 277.33 | 3.29 | 3.29 |
| 349.39 | 0.18 | 0.18 |
| 495.64 | 5.27 | 5.27 |
| 308.37 | 0.94 | 0.94 |
| 302.41 | 3.62 | 3.62 |
| 274.18 | ||
| 480.65 | 4.94 | 4.94 |
| 327.18 | 4.09 | 4.09 |
| 518.56 | 6.38 | 6.38 |
| 225.25 | 2.03 | 2.03 |
| 434.53 | 4.60 | 4.60 |
| 504.64 | -0.02 | -0.02 |
| 322.36 | 2.75 | 2.75 |
| 418.28 | 3.49 | 3.49 |
| 379.46 | 2.25 | 2.25 |
| 216.28 | 1.77 | 1.77 |
| 270.21 | 3.25 | 3.25 |
| 419.42 | 0.64 | 0.64 |
| 296.55 | 3.62 | 3.62 |
| 291.44 | 4.56 | 4.56 |
| 351.86 | 2.69 | 2.69 |
| 331.80 | 3.33 | 3.33 |
| 344.91 | 4.34 | 4.34 |
| 182.08 | ||
| 193.25 | 2.79 | 2.79 |
| 463.34 | 3.94 | 3.94 |
| 290.41 | 3.79 | 3.79 |
| 448.44 | 1.65 | 1.65 |
| 228.25 | 2.97 | 2.97 |
| 307.40 | 2.77 | 2.77 |
| 325.45 | 3.77 | 3.77 |
| 214.18 | 0.16 | 0.16 |
| 244.25 | 2.68 | 2.68 |
| 304.31 | 3.37 | 3.37 |
| 382.89 | 4.89 | 4.89 |
| 350.46 | 4.15 | 4.15 |
| 469.67 | 7.22 | 7.22 |
| 366.55 | 4.83 | 4.83 |
| 326.44 | 3.52 | 3.52 |
| 279.34 | 0.98 | 0.98 |
| 447.36 | 4.83 | 4.83 |
| 385.51 | 1.20 | 1.20 |
| 282.39 | 4.42 | 4.42 |
| 131.18 | 0.59 | 0.59 |
| 287.32 | 3.10 | 3.10 |
| 304.39 | 3.15 | 3.15 |
| 316.33 | 3.79 | 3.79 |
| 364.42 | 3.04 | 3.04 |
| 445.55 | 2.08 | 2.08 |
| 253.72 | 1.72 | 1.72 |
| 264.33 | 3.25 | 3.25 |
| 195.26 | 3.56 | 3.56 |
| 213.24 | 3.51 | 3.51 |
| 302.37 | 3.57 | 3.57 |
| 303.41 | 4.89 | 4.89 |
| 136.20 | 0.69 | 0.69 |
| 179.22 | 0.72 | 0.72 |
| 650.76 | 3.93 | 3.93 |
| 373.88 | 2.90 | 2.90 |
| 249.32 | 2.47 | 2.47 |
| 286.36 | 3.59 | 3.59 |
| 293.37 | 3.41 | 3.41 |
| 356.56 | 4.40 | 4.40 |
| 256.69 | 3.66 | 3.66 |
| 307.35 | 3.30 | 3.30 |
| 181.22 | 0.57 | 0.57 |
| 291.38 | 1.22 | 1.22 |
| 380.50 | 3.12 | 3.12 |
| 497.50 | 1.02 | 1.02 |
| 371.22 | 4.05 | 4.05 |
| 176.31 | 1.17 | 1.17 |
| 284.31 | 2.90 | 2.90 |
| 327.34 | 3.05 | 3.05 |
| 359.73 | 2.43 | 2.43 |
| 456.68 | 6.17 | 6.17 |
| 317.43 | 3.24 | 3.24 |
| 138.17 | 0.40 | 0.40 |
| 510.29 | 0.41 | 0.41 |
| 345.53 | 3.57 | 3.57 |
| 248.28 | 1.56 | 1.56 |
| 604.70 | 3.54 | 3.54 |
| 277.28 | 4.42 | 4.42 |
| 256.26 | 2.70 | 2.70 |
| 404.16 | -2.62 | -2.62 |
| 553.28 | -0.91 | -0.91 |
| 354.46 | 3.20 | 3.20 |
| 385.42 | 0.48 | 0.48 |
| 392.50 | 3.41 | 3.41 |
| 265.34 | 0.73 | 0.73 |
| 292.21 | 4.79 | 4.79 |
| 531.44 | 4.21 | 4.21 |
| 281.36 | 3.15 | 3.15 |
| 244.29 | 2.29 | 2.29 |
| 116.12 | -1.06 | -1.06 |
| 324.44 | 3.60 | 3.60 |
| 356.18 | 5.18 | 5.18 |
| 385.90 | 3.93 | 3.93 |
| 573.64 | ||
| 434.71 | 4.01 | 4.01 |
| 406.50 | 3.21 | 3.21 |
| 606.78 | 8.68 | 8.68 |
| 592.69 | 2.88 | 2.88 |
| 244.24 | 3.42 | 3.42 |
| 279.10 | -0.20 | -0.20 |
| 337.42 | 4.41 | 4.41 |
| 395.42 | 2.53 | 2.53 |
| 305.29 | 3.12 | 3.12 |
| 305.73 | 1.07 | 1.07 |
| 461.56 | 5.86 | 5.86 |
| 425.92 | 3.35 | 3.35 |
| 478.55 | 5.18 | 5.18 |
| 418.45 | 2.97 | 2.97 |
| 304.39 | 2.36 | 2.36 |
| 584.66 | -1.51 | -1.51 |
| 433.72 | 4.61 | 4.61 |
| 476.79 | 4.68 | 4.68 |
| 451.68 | 5.28 | 5.28 |
| 362.47 | 1.78 | 1.78 |
| 426.52 | 4.60 | 4.60 |
| 360.01 | 3.51 | 3.51 |
| 327.12 | 3.86 | 3.86 |
| 396.83 | 3.76 | 3.76 |
| 434.28 | 6.35 | 6.35 |
| 276.68 | 3.50 | 3.50 |
| 481.68 | 6.23 | 6.23 |
| 178.14 | 1.20 | 1.20 |
| 384.26 | 3.96 | 3.96 |
| 434.43 | 0.22 | 0.22 |
| 479.53 | 3.68 | 3.68 |
| 266.69 | 1.29 | 1.29 |
| 376.91 | 3.62 | 3.62 |
| 310.40 | 1.73 | 1.73 |
| 416.28 | 2.43 | 2.43 |
| 324.83 | 2.48 | 2.48 |
| 417.63 | 6.79 | 6.79 |
| 244.21 | -3.17 | -3.17 |
| 611.74 | 6.48 | 6.48 |
| 346.47 | 2.81 | 2.81 |
| 346.34 | 2.18 | 2.18 |
| 248.31 | 1.96 | 1.96 |
| 260.25 | 0.37 | 0.37 |
| 241.25 | 1.91 | 1.91 |
| 249.34 | 3.06 | 3.06 |
| 343.43 | 4.69 | 4.69 |
| 207.25 | 1.81 | 1.81 |
| 249.34 | 2.80 | 2.80 |
| 182.18 | 1.03 | 1.03 |
| 471.56 | 2.88 | 2.88 |
| 492.53 | 4.28 | 4.28 |
| 372.42 | 4.03 | 4.03 |
| 360.37 | 2.57 | 2.57 |
| 373.50 | 3.64 | 3.64 |
| 248.32 | 2.76 | 2.76 |
| 343.90 | 5.10 | 5.10 |
| 264.13 | 2.99 | 2.99 |
| 257.68 | -0.60 | -0.60 |
| 332.85 | 1.58 | 1.58 |
| 263.34 | 4.05 | 4.05 |
| 264.22 | 0.41 | 0.41 |
| 311.34 | 3.21 | 3.21 |
| 415.42 | -1.13 | -1.13 |
| 384.31 | 1.45 | 1.45 |
| 285.40 | 3.33 | 3.33 |
| 583.69 | 2.08 | 2.08 |
| 376.58 | 5.66 | 5.66 |
| 316.47 | 4.18 | 4.18 |
| 357.16 | ||
| 496.68 | 3.80 | 3.80 |
| 490.65 | 3.87 | 3.87 |
| 257.27 | 1.95 | 1.95 |
| 176.22 | 1.37 | 1.37 |
| 361.53 | 5.53 | 5.53 |
| 611.74 | 2.72 | 2.72 |
| 193.16 | 1.66 | 1.66 |
| 371.46 | 2.64 | 2.64 |
| 331.46 | 5.32 | 5.32 |
| 306.37 | 1.07 | 1.07 |
| 452.56 | 3.91 | 3.91 |
| 203.24 | 0.85 | 0.85 |
| 774.17 | 3.85 | 3.85 |
| 228.38 | 3.04 | 3.04 |
| 836.39 | -2.45 | -2.45 |
| 368.50 | 4.73 | 4.73 |
| 267.36 | 3.13 | 3.13 |
| 170.17 | -0.39 | -0.39 |
| 33.03 | -0.67 | -0.67 |
| 652.26 | 10.29 | 10.29 |
| 149.10 | -2.16 | -2.16 |
| 285.23 | 2.33 | 2.33 |
| 183.18 | 0.78 | 0.78 |
| 244.23 | 1.82 | 1.82 |
| 181.22 | 0.28 | 0.28 |
| 247.29 | 2.08 | 2.08 |
| 231.08 | 2.66 | 2.66 |
| 249.63 | 1.56 | 1.56 |
| 101.11 | 0.43 | 0.43 |
| 555.66 | 4.26 | 4.26 |
| 277.21 | 2.38 | 2.38 |
| 358.36 | -0.24 | -0.24 |
| 523.63 | 5.53 | 5.53 |
| 398.42 | 2.91 | 2.91 |
| 429.60 | 5.41 | 5.41 |
| 650.78 | 3.28 | 3.28 |
| 522.61 | 2.97 | 2.97 |
| 277.35 | 0.83 | 0.83 |
| 404.43 | 2.96 | 2.96 |
| 366.46 | 4.15 | 4.15 |
| 344.41 | 1.82 | 1.82 |
| 211.20 | 1.35 | 1.35 |
| 327.43 | 5.74 | 5.74 |
| 213.66 | 1.38 | 1.38 |
| 491.65 | 5.96 | 5.96 |
| 198.23 | 1.87 | 1.87 |
| 287.75 | 4.00 | 4.00 |
| 438.58 | 5.32 | 5.32 |
| 467.42 | 3.81 | 3.81 |
| 481.48 | 3.98 | 3.98 |
| 252.23 | -1.56 | -1.56 |
| 394.49 | 4.04 | 4.04 |
| 379.44 | 3.89 | 3.89 |
| 220.28 | 3.48 | 3.48 |
| 261.39 | 2.71 | 2.71 |
| 610.85 | 5.21 | 5.21 |
| 269.43 | 3.81 | 3.81 |
| 160.18 | 1.27 | 1.27 |
| 810.99 | 3.99 | 3.99 |
| 319.14 | 1.02 | 1.02 |
| 350.47 | 5.16 | 5.16 |
| 268.32 | 2.72 | 2.72 |
| 416.58 | 4.85 | 4.85 |
| 586.68 | -1.44 | -1.44 |
| 250.26 | 1.87 | 1.87 |
| 419.35 | 3.74 | 3.74 |
| 337.46 | 4.22 | 4.22 |
| 508.45 | 5.68 | 5.68 |
| 291.38 | 1.22 | 1.22 |
| 280.36 | 2.11 | 2.11 |
| 249.36 | 2.74 | 2.74 |
| 310.46 | 5.07 | 5.07 |
| 351.36 | -1.24 | -1.24 |
| 375.17 | -0.39 | -0.39 |
| 745.42 | -2.57 | -2.57 |
| 222.31 | 0.64 | 0.64 |
| 70.09 | -0.14 | -0.14 |
| 466.67 | 5.22 | 5.22 |
| 247.34 | 2.17 | 2.17 |
| 616.84 | 5.75 | 5.75 |
| 392.50 | 2.39 | 2.39 |
| 875.11 | 5.60 | 5.60 |