Basic Information
ID: ALA1738684
Type: Binding
Description: PUBCHEM_BIOASSAY: SAR assay for compounds activating TNAP in the presence of 100 mM DEA performed in a luminescence assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1001, AID1056, AID1450, AID1548, AID1941, AID518, AID813]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1738684
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 223.24 | 1.93 | 1.93 |
| 295.35 | 3.04 | 3.04 |
| 610.73 | 7.85 | 7.85 |
| 357.40 | 1.88 | 1.88 |
| 332.16 | 2.56 | 2.56 |
| 351.38 | 3.64 | 3.64 |
| 334.34 | 2.44 | 2.44 |
| 266.69 | 1.78 | 1.78 |
| 399.46 | 1.35 | 1.35 |
| 276.30 | 1.61 | 1.61 |
| 204.19 | 0.76 | 0.76 |
| 293.33 | 2.74 | 2.74 |
| 369.84 | 3.87 | 3.87 |
| 371.40 | 0.57 | 0.57 |
| 373.72 | 3.22 | 3.22 |
| 412.26 | 3.16 | 3.16 |
| 284.49 | 1.47 | 1.47 |
| 383.86 | 2.28 | 2.28 |
| 282.31 | 1.59 | 1.59 |
| 337.45 | 2.56 | 2.56 |
| 246.27 | 1.38 | 1.38 |
| 246.27 | 1.44 | 1.44 |
| 325.37 | 2.89 | 2.89 |
| 298.46 | 4.00 | 4.00 |
| 268.41 | 1.87 | 1.87 |
| 208.26 | 1.71 | 1.71 |
| 369.79 | 0.19 | 0.19 |
| 303.39 | 2.08 | 2.08 |
| 292.34 | 2.97 | 2.97 |
| 208.26 | 1.71 | 1.71 |
| 337.36 | 0.08 | 0.08 |
| 337.36 | 0.08 | 0.08 |
| 426.53 | 1.66 | 1.66 |
| 257.08 | 2.36 | 2.36 |
| 267.63 | 1.62 | 1.62 |
| 327.48 | 2.32 | 2.32 |
| 294.38 | 3.81 | 3.81 |
| 337.84 | 2.73 | 2.73 |
| 411.53 | 5.60 | 5.60 |
| 246.27 | 1.44 | 1.44 |
| 298.37 | 3.21 | 3.21 |
| 320.35 | 2.25 | 2.25 |
| 214.23 | 1.46 | 1.46 |
| 368.26 | 3.70 | 3.70 |
| 279.30 | 0.45 | 0.45 |
| 337.84 | 2.73 | 2.73 |
| 298.26 | 1.71 | 1.71 |
| 310.31 | 2.41 | 2.41 |
| 354.39 | 2.94 | 2.94 |
| 443.92 | 2.50 | 2.50 |
| 218.22 | 0.82 | 0.82 |
| 268.35 | 3.65 | 3.65 |
| 327.41 | 1.86 | 1.86 |
| 445.81 | 3.53 | 3.53 |
| 309.37 | 3.36 | 3.36 |
| 445.79 | 2.78 | 2.78 |
| 302.33 | 1.17 | 1.17 |
| 222.29 | 2.10 | 2.10 |
| 464.62 | 5.53 | 5.53 |
| 340.69 | 2.27 | 2.27 |
| 281.31 | 2.21 | 2.21 |
| 332.37 | 2.81 | 2.81 |
| 389.35 | 1.45 | 1.45 |
| 402.05 | 2.02 | 2.02 |
| 303.82 | 1.70 | 1.70 |
| 274.32 | 1.49 | 1.49 |
| 206.18 | 1.20 | 1.20 |
| 301.30 | 0.93 | 0.93 |
| 349.42 | 1.54 | 1.54 |
| 216.24 | 1.38 | 1.38 |
| 248.31 | 1.84 | 1.84 |
| 314.41 | 2.65 | 2.65 |
| 353.22 | 2.88 | 2.88 |
| 247.21 | 1.27 | 1.27 |
| 348.37 | 2.78 | 2.78 |
| 244.30 | 2.35 | 2.35 |
| 262.34 | 2.23 | 2.23 |
| 347.17 | 2.74 | 2.74 |
| 408.76 | 2.88 | 2.88 |
| 343.39 | 3.40 | 3.40 |
| 414.55 | 6.05 | 6.05 |
| 398.29 | 2.35 | 2.35 |
| 311.14 | 1.89 | 1.89 |
| 280.72 | 2.26 | 2.26 |
| 247.21 | 1.27 | 1.27 |
| 248.24 | 1.07 | 1.07 |
| 278.27 | 1.08 | 1.08 |
| 262.27 | 1.22 | 1.22 |
| 427.55 | 4.90 | 4.90 |
| 412.26 | 3.16 | 3.16 |
| 339.19 | 2.71 | 2.71 |
| 246.27 | 1.38 | 1.38 |
| 323.39 | 3.75 | 3.75 |
| 443.21 | 3.53 | 3.53 |
| 375.13 | 2.93 | 2.93 |
| 160.56 | -0.02 | -0.02 |
| 202.22 | 1.37 | 1.37 |
| 297.11 | 1.58 | 1.58 |
| 280.72 | 2.09 | 2.09 |
| 235.07 | 1.33 | 1.33 |
| 206.21 | -0.13 | -0.13 |
| 278.72 | 2.93 | 2.93 |
| 413.53 | 4.60 | 4.60 |
| 268.28 | 1.98 | 1.98 |
| 223.62 | 1.11 | 1.11 |
| 248.24 | 0.83 | 0.83 |
| 248.24 | 0.83 | 0.83 |
| 267.63 | 1.62 | 1.62 |
| 262.27 | 1.00 | 1.00 |