Basic Information
ID: ALA1743273
Type: ADME
Description: Clinically relevant substrates of human liver microsomal P450 enzymes, isoform CYP3A4
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1743273
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 914.19 | 6.18 | 6.18 |
| 804.03 | 4.64 | 4.64 |
| 581.67 | 1.99 | 1.99 |
| 385.51 | 2.09 | 2.09 |
| 358.85 | 4.18 | 4.18 |
| 404.55 | 4.20 | 4.20 |
| 339.48 | 3.36 | 3.36 |
| 749.00 | 1.90 | 1.90 |
| 733.94 | 1.79 | 1.79 |
| 426.56 | 4.13 | 4.13 |
| 398.48 | 3.33 | 3.33 |
| 313.40 | 3.19 | 3.19 |
| 393.44 | 3.41 | 3.41 |
| 236.27 | 3.39 | 3.39 |
| 670.86 | 3.09 | 3.09 |
| 613.80 | 2.87 | 2.87 |
| 505.64 | 2.40 | 2.40 |
| 369.43 | 2.74 | 2.74 |
| 471.69 | 6.45 | 6.45 |
| 336.48 | 4.14 | 4.14 |
| 416.53 | 1.38 | 1.38 |
| 343.22 | 4.23 | 4.23 |
| 374.48 | 1.80 | 1.80 |
| 325.77 | 4.32 | 4.32 |
| 308.77 | 3.58 | 3.58 |
| 296.41 | 3.61 | 3.61 |
| 141.17 | 0.45 | 0.45 |
| 412.95 | 3.81 | 3.81 |
| 389.46 | 1.35 | 1.35 |
| 383.52 | 2.86 | 2.86 |
| 628.81 | 4.33 | 4.33 |
| 237.73 | 2.90 | 2.90 |
| 212.23 | 0.62 | 0.62 |
| 389.41 | 2.21 | 2.21 |
| 393.70 | 4.40 | 4.40 |
| 359.47 | 1.55 | 1.55 |
| 369.47 | 3.46 | 3.46 |
| 312.42 | 2.32 | 2.32 |
| 528.95 | 9.15 | 9.15 |
| 477.05 | 5.09 | 5.09 |
| 458.58 | 5.35 | 5.35 |
| 810.99 | 3.99 | 3.99 |
| 1202.63 | ||
| 271.40 | 3.38 | 3.38 |
| 484.64 | 5.10 | 5.10 |
| 638.83 | 5.91 | 5.91 |
| 720.96 | 5.91 | 5.91 |
| 446.91 | 4.28 | 4.28 |
| 493.62 | 4.59 | 4.59 |
| 421.90 | 3.09 | 3.09 |
| 705.65 | 5.58 | 5.58 |
| 312.41 | 2.53 | 2.53 |
| 356.81 | 3.56 | 3.56 |
| 469.67 | 7.22 | 7.22 |
| 348.49 | 6.10 | 6.10 |
| 375.56 | 5.04 | 5.04 |
| 418.57 | 4.59 | 4.59 |
| 262.36 | 2.99 | 2.99 |
| 824.97 | 3.52 | 3.52 |
| 468.56 | 3.51 | 3.51 |
| 500.43 | 8.64 | 8.64 |
| 812.02 | 4.93 | 4.93 |
| 384.25 | ||
| 298.43 | 3.49 | 3.49 |
| 704.87 | 4.21 | 4.21 |
| 357.49 | 3.34 | 3.34 |
| 415.57 | 4.11 | 4.11 |
| 540.71 | 1.43 | 1.43 |
| 324.42 | 3.17 | 3.17 |
| 324.42 | 3.17 | 3.17 |
| 430.54 | 2.72 | 2.72 |
| 451.38 | 5.50 | 5.50 |
| 344.50 | 4.08 | 4.08 |
| 279.86 | 4.74 | 4.74 |
| 461.56 | 5.86 | 5.86 |
| 288.43 | 3.88 | 3.88 |
| 425.92 | 3.35 | 3.35 |
| 418.45 | 2.97 | 2.97 |
| 392.47 | 1.90 | 1.90 |
| 602.68 | 7.33 | 7.33 |
| 847.02 | 4.62 | 4.62 |
| 534.43 | 4.95 | 4.95 |
| 384.26 | 3.96 | 3.96 |
| 479.53 | 3.68 | 3.68 |
| 474.59 | 1.61 | 1.61 |
| 558.65 | 6.31 | 6.31 |
| 408.88 | 2.27 | 2.27 |
| 382.46 | 4.44 | 4.44 |
| 481.55 | 2.40 | 2.40 |
| 346.34 | 2.18 | 2.18 |
| 382.53 | 3.82 | 3.82 |
| 353.51 | 4.65 | 4.65 |
| 488.61 | 2.07 | 2.07 |
| 360.37 | 2.57 | 2.57 |
| 371.39 | 2.58 | 2.58 |
| 388.42 | 3.20 | 3.20 |
| 465.95 | 3.36 | 3.36 |
| 778.95 | 4.75 | 4.75 |
| 747.96 | 2.44 | 2.44 |
| 298.38 | 2.84 | 2.84 |
| 424.99 | 0.39 | 0.39 |
| 321.83 | 3.67 | 3.67 |
| 414.50 | 3.12 | 3.12 |
| 448.48 | 4.26 | 4.26 |
| 528.54 | 6.58 | 6.58 |
| 444.52 | 3.47 | 3.47 |
| 310.44 | 3.66 | 3.66 |
| 429.60 | 5.41 | 5.41 |
| 426.59 | 3.37 | 3.37 |
| 624.87 | 5.46 | 5.46 |
| 1163.35 | 1.99 | 1.99 |
| 377.92 | 2.49 | 2.49 |
| 448.60 | ||
| 363.24 | 3.87 | 3.87 |
| 577.73 | 2.52 | 2.52 |
| 958.24 | 6.20 | 6.20 |
| 491.54 | 3.82 | 3.82 |
| 861.94 | 3.26 | 3.26 |