Basic Information
ID: ALA1763144
Type: Functional
Description: Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium level by aequorin bioluminescence assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA1763144
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 397.86 | 3.97 | 3.97 |
| 410.86 | 3.23 | 3.23 |
| 430.43 | 4.07 | 4.07 |
| 391.86 | 3.56 | 3.56 |
| 362.43 | 3.05 | 3.05 |
| 398.49 | 2.60 | 2.60 |
| 410.91 | 4.09 | 4.09 |
| 410.91 | 4.09 | 4.09 |
| 424.93 | 4.48 | 4.48 |
| 410.91 | 3.71 | 3.71 |
| 410.91 | 3.71 | 3.71 |
| 409.92 | 4.61 | 4.61 |
| 363.42 | 3.31 | 3.31 |
| 446.43 | 3.95 | 3.95 |
| 376.46 | 3.36 | 3.36 |
| 440.53 | 2.45 | 2.45 |
| 387.44 | 2.92 | 2.92 |
| 431.32 | 4.35 | 4.35 |
| 363.42 | 2.44 | 2.44 |
| 363.42 | 2.44 | 2.44 |
| 363.42 | 2.44 | 2.44 |
| 368.48 | 3.43 | 3.43 |
| 382.85 | 3.40 | 3.40 |
| 409.88 | 2.79 | 2.79 |
| 431.32 | 4.35 | 4.35 |
| 490.97 | 5.41 | 5.41 |
| 439.90 | 2.56 | 2.56 |
| 376.46 | 2.97 | 2.97 |
| 380.42 | 3.19 | 3.19 |
| 380.42 | 3.19 | 3.19 |
| 380.42 | 3.19 | 3.19 |
| 396.88 | 3.70 | 3.70 |
| 410.91 | 3.70 | 3.70 |
| 381.87 | 3.08 | 3.08 |
| 381.87 | 3.08 | 3.08 |
| 381.87 | 3.08 | 3.08 |
| 386.93 | 4.07 | 4.07 |
| 396.88 | 3.70 | 3.70 |
| 396.88 | 3.70 | 3.70 |
| 434.85 | 4.71 | 4.71 |
| 380.88 | 4.00 | 4.00 |
| 408.51 | 4.71 | 4.71 |
| 394.91 | 4.25 | 4.25 |
| 332.41 | 3.04 | 3.04 |