Basic Information
ID: ALA1763551
Type: Binding
Description: Inhibition of CDK5/p25 assessed as [33P]gamma-ATP incorporation into peptide PKTPKKAKKL substrate after 45 mins by scintillation counter
Format: BAO_0000223
Target: Cyclin-dependent kinase 5/CDK5 activator 1(ALA1907600)
Document: ALA1759882
Inhibition of CDK5/p25 assessed as [33P]gamma-ATP incorporation into peptide PKTPKKAKKL substrate after 45 mins by scintillation counter: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1763551
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 354.46 | 3.20 | 3.20 |
| 374.81 | 4.26 | 4.26 |
| 347.80 | 4.49 | 4.49 |
| 359.84 | 4.36 | 4.36 |
| 320.39 | 2.26 | 2.26 |
| 320.39 | 2.26 | 2.26 |
| 328.37 | 3.42 | 3.42 |
| 342.40 | 3.88 | 3.88 |
| 356.43 | 3.91 | 3.91 |
| 314.35 | 3.23 | 3.23 |
| 314.35 | 3.23 | 3.23 |
| 314.35 | 3.23 | 3.23 |
| 326.38 | 3.10 | 3.10 |
| 326.38 | 3.10 | 3.10 |
| 326.38 | 3.10 | 3.10 |
| 314.35 | 3.23 | 3.23 |
| 314.35 | 3.23 | 3.23 |
| 314.35 | 3.23 | 3.23 |
| 296.36 | 3.09 | 3.09 |
| 341.35 | 3.00 | 3.00 |
| 326.38 | 3.10 | 3.10 |
| 326.38 | 3.10 | 3.10 |
| 326.38 | 3.10 | 3.10 |
| 314.35 | 3.23 | 3.23 |
| 314.35 | 3.23 | 3.23 |
| 314.35 | 3.23 | 3.23 |
| 326.38 | 3.10 | 3.10 |
| 326.38 | 3.10 | 3.10 |
| 326.38 | 3.10 | 3.10 |
| 297.34 | 2.49 | 2.49 |
| 297.34 | 2.49 | 2.49 |
| 297.34 | 2.49 | 2.49 |
| 328.37 | 3.69 | 3.69 |
| 382.34 | 4.25 | 4.25 |