Basic Information
ID: ALA1763680
Type: ADME
Description: Inhibition of CYP3A4 in human liver microsomes at 10 uM preincubated with compound for 30 mins in presence of NADPH followed by incubation with substrate
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA1763680
TDI
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 510.98 | 4.02 | 4.02 |
| 486.58 | 3.54 | 3.54 |
| 490.61 | 3.46 | 3.46 |