Basic Information
ID: ALA1763684
Type: ADME
Description: Inhibition of CYP2D6 in human liver microsomes at 10 uM preincubated with compound for 30 mins in presence of NADPH followed by incubation with substrate
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Target: Cytochrome P450 2D6(ALA289)
Document: ALA1759854
Inhibition of CYP2D6 in human liver microsomes at 10 uM preincubated with compound for 30 mins in presence of NADPH followed by incubation with substrate: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1763684
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 490.61 | 3.46 | 3.46 |