Basic Information
ID: ALA1763978
Type: Functional
Description: Inhibition of hepatic cholesterol biosynthesis in NMRI mouse at 3 mg/kg, po administered 1 hr before administering [14C]mevalonate as substrate measured after 10 mins
Organism: Mus musculus
Strain: NMRI
Activity Charts
Bioactivity
Activity Types for Assay ALA1763978
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 420.34 | 5.18 | 5.18 |
| 448.39 | 5.66 | 5.66 |
| 399.92 | 4.84 | 4.84 |
| 403.88 | 4.67 | 4.67 |
| 385.89 | 4.53 | 4.53 |
| 418.32 | 5.10 | 5.10 |
| 436.34 | 4.30 | 4.30 |
| 454.35 | 5.38 | 5.38 |
| 385.89 | 4.53 | 4.53 |
| 464.79 | 5.29 | 5.29 |
| 415.92 | 4.54 | 4.54 |
| 445.94 | 4.55 | 4.55 |
| 533.50 | 5.86 | 5.86 |
| 545.51 | 5.81 | 5.81 |
| 531.48 | 5.42 | 5.42 |
| 483.05 | 5.46 | 5.46 |
| 527.06 | 4.78 | 4.78 |
| 557.09 | 4.78 | 4.78 |
| 557.09 | 4.78 | 4.78 |
| 557.09 | 4.78 | 4.78 |