Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current response at 100 nM by voltage clam...

Basic Information

ID: ALA1763990

Type: Functional

Description: Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current response at 100 nM by voltage clamp electrophysiology assay

Format: BAO_0000019

Target: Neuronal acetylcholine receptor; alpha9/alpha10(ALA2109238)

Document: ALA1759897

Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current response at 100 nM by voltage clamp electrophysiology assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA1763990

Activity

Total(40)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
834.58	6.90	6.90
834.58	6.90	6.90
900.60	8.50	8.50
978.71	10.05	10.05
918.74	9.07	9.07
846.68	8.64	8.64
846.68	8.64	8.64
912.69	10.25	10.25
912.69	10.25	10.25
990.81	11.79	11.79
930.84	10.82	10.82
1086.73	8.63	8.63
1086.73	8.63	8.63
1174.76	10.78	10.78
1278.91	12.83	12.83
1102.86	10.96	10.96
1102.86	10.96	10.96
1190.89	13.10	13.10
1295.04	15.16	15.16
554.37	4.38	4.38
554.37	4.38	4.38
610.48	6.43	6.43
562.43	5.54	5.54
626.44	6.23	6.23
582.42	5.16	5.16
582.42	5.16	5.16
582.42	5.16	5.16
626.44	6.23	6.23
626.44	6.23	6.23
678.51	7.26	7.26
602.41	5.27	5.27
590.49	6.32	6.32
590.49	6.32	6.32
634.50	7.39	7.39
634.50	7.39	7.39
590.49	6.32	6.32
634.50	7.39	7.39
634.50	7.39	7.39
562.43	5.54	5.54
610.48	6.43	6.43