Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiology...

Basic Information

ID: ALA1763991

Type: Functional

Description: Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiology assay

Format: BAO_0000019

Target: Neuronal acetylcholine receptor; alpha9/alpha10(ALA2109238)

Document: ALA1759897

Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiology assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA1763991

IC50

Total(8)

Parent Molecular Weight	ALogP	Polar Surface Area
978.71	10.05	10.05
912.69	10.25	10.25
912.69	10.25	10.25
990.81	11.79	11.79
1278.91	12.83	12.83
1295.04	15.16	15.16
610.48	6.43	6.43
602.41	5.27	5.27

Parent Molecular Weight

ALogP

Polar Surface Area

978.71

10.05

912.69

10.25

912.69

10.25

990.81

11.79

1278.91

12.83

1295.04

15.16

610.48

6.43

602.41

5.27

Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiology...

Basic Information

Activity Charts

Compound Summary