Basic Information
ID: ALA1764035
Type: Functional
Description: Inhibition of 11beta-HSD1 in ICR mouse assessed as inhibition of conversion of [3H]-cortisone to [3H]-cortisol at 10 mg/kg, po administered 16 hrs before [3H]-cortisone challenge
Organism: Mus musculus
Strain: ICR
Activity Charts
Bioactivity
Activity Types for Assay ALA1764035
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 419.49 | 5.85 | 5.85 |
| 423.50 | 6.62 | 6.62 |
| 441.49 | 6.92 | 6.92 |
| 421.51 | 5.91 | 5.91 |
| 393.45 | 5.13 | 5.13 |
| 475.94 | 6.83 | 6.83 |
| 519.59 | 5.58 | 5.58 |
| 442.51 | 3.64 | 3.64 |
| 456.53 | 4.03 | 4.03 |
| 470.56 | 4.42 | 4.42 |
| 423.55 | 6.24 | 6.24 |
| 439.55 | 5.25 | 5.25 |
| 455.55 | 4.92 | 4.92 |
| 441.52 | 4.53 | 4.53 |
| 469.57 | 5.31 | 5.31 |
| 469.57 | 5.31 | 5.31 |
| 483.60 | 5.70 | 5.70 |
| 503.59 | 5.96 | 5.96 |
| 521.58 | 6.10 | 6.10 |
| 495.49 | 5.42 | 5.42 |
| 509.52 | 5.46 | 5.46 |
| 441.52 | 4.53 | 4.53 |
| 469.57 | 5.31 | 5.31 |
| 483.60 | 5.70 | 5.70 |
| 421.99 | 4.55 | 4.55 |
| 437.99 | 4.26 | 4.26 |
| 466.45 | 4.66 | 4.66 |
| 401.58 | 4.21 | 4.21 |